Annotation Summary for Cell Line: NCI-H1299  

Cell line primary name: NCI-H1299
Cell line aliases: H1299
Gender: M
Site Primary: lung
Histology: carcinoma
Hist Subtype1: non_small_cell_carcinoma
Notes:
Source: ATCC
Expression arrays: PARES_p_NCLE_RNA_Redo_HG-U133_Plus_2_E09_257710
SNP arrays: FASTS_p_NCLE_DNAAffy4_S_GenomeWideSNP_6_A01_335188
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in NCI-H1299

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ACACB p.D1383Y 12 109671560 109671560 NCIH1299_LUNG 37 Missense_Mutation SNP G T uc001tob.2 ACACB_uc001toc.... Hybrid_Cap... view
ADAM28 8 24211994 24211997 NCIH1299_LUNG 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 NCIH1299_LUNG 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP9 p.1335_1336insQ 7 91652178 91652179 NCIH1299_LUNG 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ALPK1 4 113347609 113347610 NCIH1299_LUNG 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
ARID1A 1 27107263 27107264 NCIH1299_LUNG 37 3'UTR Ins - C rs3841356 uc001bmv.1 ARID1A_uc001bmu... Hybrid_Cap...
ASTN1 1 177133895 177133895 NCIH1299_LUNG 37 5'UTR SNP G T uc001glc.2 ASTN1_uc001glb.... Hybrid_Cap... view
CACNB2 p.K8N 10 18429689 18429689 NCIH1299_LUNG 37 Missense_Mutation SNP G C uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap... view
CACNB2 10 18828704 18828705 NCIH1299_LUNG 37 3'UTR Ins - AACA uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CD40LG p.I98M X 135736537 135736537 NCIH1299_LUNG 37 Missense_Mutation SNP A G uc004faa.2 CD40LG_uc010nsd... Hybrid_Cap... view
CD44 p.S612fs 11 35236423 35236424 NCIH1299_LUNG 37 Frame_Shift_Ins Ins - T uc001mvu.2 CD44_uc001mvv.2... Hybrid_Cap...
CDKN1A 6 36653802 36653802 NCIH1299_LUNG 37 3'UTR SNP G T uc011dtq.1 CDKN1A_uc003omm... Hybrid_Cap... view
CHD8 p.R1058Q 14 21870168 21870168 NCIH1299_LUNG 37 Missense_Mutation SNP C T uc001was.1 CHD8_uc001war.1... Hybrid_Cap... view
CLTC p.E1628del 17 57768031 57768033 NCIH1299_LUNG 37 In_Frame_Del Del AAG - uc002ixr.1 CLTC_uc002ixp.2... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 NCIH1299_LUNG 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN6 p.L105R 3 1269633 1269633 NCIH1299_LUNG 37 Missense_Mutation SNP T G uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap... view
CNTN6 3 1339681 1339686 NCIH1299_LUNG 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
COL3A1 p.P245fs 2 189854864 189854864 NCIH1299_LUNG 37 Frame_Shift_Del Del C - uc002uqj.1 COL3A1_uc010frw... Hybrid_Cap...
CREB3L2 p.T100del 7 137612914 137612916 NCIH1299_LUNG 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CTDSPL 3 38022581 38022581 NCIH1299_LUNG 37 3'UTR SNP G C uc003chg.2 CTDSPL_uc003chh... Hybrid_Cap... view
DYRK1A 21 38884966 38884967 NCIH1299_LUNG 37 3'UTR Ins - T rs72430212 uc002ywk.2 DYRK1A_uc002ywi... Hybrid_Cap...
EPHA6 3 97367230 97367231 NCIH1299_LUNG 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
EPHA7 6 93953014 93953014 NCIH1299_LUNG 37 3'UTR SNP T G uc003poe.2 EPHA7_uc003pof.... Hybrid_Cap... view
ERN2 16 23712275 23712275 NCIH1299_LUNG 37 Intron Del C - uc002dma.3 ERN2_uc010bxp.2... Hybrid_Cap...
FGFR1OP 6 167453519 167453520 NCIH1299_LUNG 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 NCIH1299_LUNG 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLI1 11 128638217 128638217 NCIH1299_LUNG 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FN1 2 216244182 216244185 NCIH1299_LUNG 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GCK p.M225I 7 44189366 44189366 NCIH1299_LUNG 37 Missense_Mutation SNP C T uc003tkk.1 GCK_uc003tkj.1_... Hybrid_Cap... view
GPR112 p.D2657del X 135474445 135474447 NCIH1299_LUNG 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 NCIH1299_LUNG 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GRK7 p.P117H 3 141497476 141497476 NCIH1299_LUNG 37 Missense_Mutation SNP C A uc011bnd.1 Hybrid_Cap... view
HGF 7 81372123 81372123 NCIH1299_LUNG 37 Intron SNP C G uc003uhl.2 HGF_uc003uhm.2_... Hybrid_Cap... view
HIF1A 14 62213929 62213930 NCIH1299_LUNG 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HNF1A 12 121434630 121434631 NCIH1299_LUNG 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
HUNK p.K358E 21 33346928 33346928 NCIH1299_LUNG 37 Missense_Mutation SNP A G uc002yph.2 Hybrid_Cap... view
ILK 11 6630029 6630029 NCIH1299_LUNG 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 NCIH1299_LUNG 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KIAA2022 p.E565G X 73962698 73962698 NCIH1299_LUNG 37 Missense_Mutation SNP T C uc004eby.2 Hybrid_Cap... view
KLK7 19 51480672 51480675 NCIH1299_LUNG 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LRGUK p.P683L 7 133932372 133932372 NCIH1299_LUNG 37 Missense_Mutation SNP C T uc003vrm.1 Hybrid_Cap... view
LRP2 p.E4293D 2 170002366 170002366 NCIH1299_LUNG 37 Missense_Mutation SNP T A uc002ues.2 Hybrid_Cap... view
LTK p.P463R 15 41799446 41799446 NCIH1299_LUNG 37 Missense_Mutation SNP G C uc001zoa.3 LTK_uc001zob.3_... Hybrid_Cap... view
MAML2 p.604_607QQQQ>Q 11 95825375 95825383 NCIH1299_LUNG 37 In_Frame_Del Del TGCTG... - rs113349418 uc001pfw.1 Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 NCIH1299_LUNG 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 NCIH1299_LUNG 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 NCIH1299_LUNG 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAPKBP1 15 42111753 42111754 NCIH1299_LUNG 37 Intron Ins - C rs3034891 uc001zok.3 MAPKBP1_uc001zo... Hybrid_Cap...
MYO3B p.I227V 2 171092576 171092576 NCIH1299_LUNG 37 Missense_Mutation SNP A G uc002ufy.2 MYO3B_uc002ufv.... Hybrid_Cap... view
MYT1 20 62871868 62871868 NCIH1299_LUNG 37 3'UTR SNP G A uc002yii.2 MYT1_uc002yij.2... Hybrid_Cap... view
NCAM1 11 112832307 112832308 NCIH1299_LUNG 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 NCIH1299_LUNG 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA3 p.Q1276del 20 46279837 46279839 NCIH1299_LUNG 37 In_Frame_Del Del CAG - rs2664555 uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NEK1 p.E346G 4 170483331 170483331 NCIH1299_LUNG 37 Missense_Mutation SNP T C uc003isd.1 NEK1_uc003isb.1... Hybrid_Cap... view
NEK3 p.K313_splice 13 52718050 52718051 NCIH1299_LUNG 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NIN p.T1742M 14 51210210 51210210 NCIH1299_LUNG 37 Missense_Mutation SNP G A uc001wyi.2 NIN_uc001wyj.2_... Hybrid_Cap... view
NOTCH4 p.16_16L>LL 6 32191658 32191659 NCIH1299_LUNG 37 In_Frame_Ins Ins - AGC rs67287835 uc003obb.2 NOTCH4_uc011dpu... Hybrid_Cap...
NPR1 1 153652964 153652964 NCIH1299_LUNG 37 Intron SNP C T uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap... view
NPR1 1 153665919 153665920 NCIH1299_LUNG 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 NCIH1299_LUNG 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NRAS p.Q61K 1 115256530 115256530 NCIH1299_LUNG 37 Missense_Mutation SNP G T uc009wgu.2 Hybrid_Cap... view
NUAK1 p.V577M 12 106460837 106460837 NCIH1299_LUNG 37 Missense_Mutation SNP C T uc001tlj.1 Hybrid_Cap... view
PAX3 2 223158653 223158653 NCIH1299_LUNG 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PDE4DIP 1 144931738 144931738 NCIH1299_LUNG 37 Intron SNP G A rs3839010 uc001elw.3 NBPF10_uc009wir... Hybrid_Cap... view
PEX5L p.D113N 3 179597885 179597885 NCIH1299_LUNG 37 Missense_Mutation SNP C T uc003fki.1 PEX5L_uc011bqd.... Hybrid_Cap... view
PMS1 2 190670539 190670540 NCIH1299_LUNG 37 Intron Ins - A rs3214425 uc002urh.3 PMS1_uc010zga.1... Hybrid_Cap...
PREX2 p.C243F 8 68950416 68950416 NCIH1299_LUNG 37 Missense_Mutation SNP G T uc003xxv.1 PREX2_uc003xxu.... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 NCIH1299_LUNG 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
RBPJ p.R238* 4 26426291 26426291 NCIH1299_LUNG 37 Nonsense_Mutation SNP C T rs5007634 uc003grx.1 RBPJ_uc003gry.1... Hybrid_Cap... view
RECQL4 p.R766fs 8 145738768 145738768 NCIH1299_LUNG 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RPS6KA5 14 91360733 91360734 NCIH1299_LUNG 37 Intron Ins - T rs77438853 uc001xys.2 RPS6KA5_uc010tw... Hybrid_Cap...
RPS6KL1 14 75373468 75373468 NCIH1299_LUNG 37 3'UTR SNP G T uc001xqx.1 RPS6KL1_uc001xq... Hybrid_Cap... view
RPS6KL1 14 75373626 75373627 NCIH1299_LUNG 37 3'UTR Ins - TGAT uc001xqx.1 RPS6KL1_uc001xq... Hybrid_Cap...
RUNX1T1 p.P69L 8 93029507 93029507 NCIH1299_LUNG 37 Missense_Mutation SNP G A uc011lgi.1 RUNX1T1_uc003yf... Hybrid_Cap... view
SEPT9 17 75494787 75494788 NCIH1299_LUNG 37 3'UTR Ins - C rs5822173 uc002jts.3 SEPT9_uc010wtk.... Hybrid_Cap...
SOS1 p.Y215H 2 39281832 39281832 NCIH1299_LUNG 37 Missense_Mutation SNP A G uc002rrk.3 SOS1_uc010ynr.1... Hybrid_Cap... view
TACC3 4 1739519 1739527 NCIH1299_LUNG 37 Intron Del GCCAT... - rs114226356 uc003gdo.2 TACC3_uc010ibz.... Hybrid_Cap...
TCL6 p.V160V 14 96137753 96137753 NCIH1299_LUNG 37 Silent SNP G C uc001yeq.2 TCL6_uc001yep.1... Hybrid_Cap... view
TLK1 2 171850178 171850179 NCIH1299_LUNG 37 3'UTR Ins - AA rs71008739 uc002ugo.2 TLK1_uc002ugn.2... Hybrid_Cap...
TNN p.D457Y 1 175063170 175063170 NCIH1299_LUNG 37 Missense_Mutation SNP G T uc001gkl.1 TNN_uc010pmx.1_... Hybrid_Cap... view
TRIM33 1 114940215 114940216 NCIH1299_LUNG 37 3'UTR Ins - G rs68133208 uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TRIM42 3 140419844 140419844 NCIH1299_LUNG 37 3'UTR SNP G C uc003eto.1 Hybrid_Cap... view
TRPS1 8 116635872 116635873 NCIH1299_LUNG 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TTN 2 179391639 179391640 NCIH1299_LUNG 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.P20079H 2 179443817 179443817 NCIH1299_LUNG 37 Missense_Mutation SNP G T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.A12985G 2 179484385 179484386 NCIH1299_LUNG 37 Missense_Mutation DNP GG TC uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.N180S 2 179665166 179665166 NCIH1299_LUNG 37 Missense_Mutation SNP T C uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 NCIH1299_LUNG 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
WDHD1 p.R910* 14 55424327 55424327 NCIH1299_LUNG 37 Nonsense_Mutation SNP G A uc001xbm.1 WDHD1_uc010aom.... Hybrid_Cap... view
ZNF423 16 49856650 49856650 NCIH1299_LUNG 37 Splice_Site_SNP SNP C A uc002efs.2 Hybrid_Cap... view