Annotation Summary for Cell Line: NCI-H1341  

Cell line primary name: NCI-H1341
Cell line aliases: H1341
Gender: F
Site Primary: lung
Histology: carcinoma
Hist Subtype1: small_cell_carcinoma
Notes:
Source: ATCC
Expression arrays: AGENT_p_NCLE_RNA6_HG-U133_Plus_2_E04_436560
SNP arrays: LOBBY_p_NCLE_DNAAffy6_GenomeWideSNP_6_G08_437374
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in NCI-H1341

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ACACA 17 35766564 35766564 NCIH1341_LUNG 37 5'UTR Del A - uc002hno.2 ACACA_uc002hnn.... Hybrid_Cap...
ADAM17 2 9630245 9630245 NCIH1341_LUNG 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 NCIH1341_LUNG 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADCK1 14 78390632 78390637 NCIH1341_LUNG 37 Intron Del AAACT... - rs78274857;rs74969652 uc001xui.2 ADCK1_uc010tvo.... Hybrid_Cap...
AKAP9 p.1335_1336insQ 7 91652178 91652179 NCIH1341_LUNG 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 NCIH1341_LUNG 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ASPH p.A264_splice 8 62550924 62550925 NCIH1341_LUNG 37 Splice_Site_Ins Ins - A rs5891816 uc003xuj.2 ASPH_uc011leg.1... Hybrid_Cap...
BCR 22 23631813 23631814 NCIH1341_LUNG 37 Intron Ins - C rs66503844 uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BCR 22 23632777 23632778 NCIH1341_LUNG 37 Intron Ins - T uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BNIP3 p.H173Y 10 133784164 133784164 NCIH1341_LUNG 37 Missense_Mutation SNP G A uc001lkv.1 BNIP3_uc001lku.... Hybrid_Cap... view
BRCA2 p.A75P 13 32893369 32893369 NCIH1341_LUNG 37 Missense_Mutation SNP G C rs28897701 uc001uub.1 BRCA2_uc001uua.... Hybrid_Cap... view
CABC1 1 227171585 227171585 NCIH1341_LUNG 37 Intron Del T - uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CACNB2 10 18828721 18828722 NCIH1341_LUNG 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 NCIH1341_LUNG 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CREB3L2 p.T100del 7 137612914 137612916 NCIH1341_LUNG 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CSMD3 p.G2851D 8 113308124 113308124 NCIH1341_LUNG 37 Missense_Mutation SNP C T uc003ynu.2 CSMD3_uc003yns.... Hybrid_Cap... view
CSNK1G3 5 122950254 122950255 NCIH1341_LUNG 37 3'UTR Ins - T rs117378469 uc003ktl.2 CSNK1G3_uc003kt... Hybrid_Cap...
CSPG4 15 75967853 75967853 NCIH1341_LUNG 37 3'UTR SNP G T uc002baw.2 Hybrid_Cap... view
CXCR2 p.A91V 2 218999796 218999796 NCIH1341_LUNG 37 Missense_Mutation SNP C T uc002vgz.1 CXCR2_uc002vha.... Hybrid_Cap... view
DFNA5 7 24783982 24783982 NCIH1341_LUNG 37 Intron Del C - uc010kus.1 DFNA5_uc003swz.... Hybrid_Cap...
DYRK1A 21 38884966 38884967 NCIH1341_LUNG 37 3'UTR Ins - T rs72430212 uc002ywk.2 DYRK1A_uc002ywi... Hybrid_Cap...
EPHA6 3 97367230 97367231 NCIH1341_LUNG 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
ERC1 p.L464F 12 1221453 1221453 NCIH1341_LUNG 37 Missense_Mutation SNP C T uc001qjb.2 ERC1_uc001qiz.2... Hybrid_Cap... view
ETV1 p.A61A 7 14017104 14017104 NCIH1341_LUNG 37 Silent SNP A T uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap... view
ETV1 7 14028708 14028708 NCIH1341_LUNG 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FGFR1OP 6 167453519 167453520 NCIH1341_LUNG 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 NCIH1341_LUNG 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLI1 11 128638217 128638217 NCIH1341_LUNG 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLNC p.E1137Q 7 128484928 128484928 NCIH1341_LUNG 37 Missense_Mutation SNP G C uc003vnz.3 FLNC_uc003voa.3... Hybrid_Cap... view
FZD1 p.93_94insP 7 90894459 90894460 NCIH1341_LUNG 37 In_Frame_Ins Ins - CCG uc003ula.2 Hybrid_Cap...
GRIA3 X 122318386 122318387 NCIH1341_LUNG 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
HIPK4 p.R353C 19 40886841 40886841 NCIH1341_LUNG 37 Missense_Mutation SNP G A uc002onp.2 Hybrid_Cap... view
HNF1A 12 121434630 121434631 NCIH1341_LUNG 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
ILK 11 6630029 6630029 NCIH1341_LUNG 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 NCIH1341_LUNG 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KLK7 19 51480672 51480675 NCIH1341_LUNG 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LAMA1 p.R2362I 18 6965396 6965397 NCIH1341_LUNG 37 Missense_Mutation DNP TC AA uc002knm.2 LAMA1_uc002knl.... Hybrid_Cap...
MAML2 p.604_607QQQQ>Q 11 95825375 95825383 NCIH1341_LUNG 37 In_Frame_Del Del TGCTG... - rs113349418 uc001pfw.1 Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 NCIH1341_LUNG 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP4K2 p.R279W 11 64567661 64567661 NCIH1341_LUNG 37 Missense_Mutation SNP G A uc001obh.2 MAP4K2_uc001obi... Hybrid_Cap... view
MAPKBP1 15 42111753 42111754 NCIH1341_LUNG 37 Intron Ins - C rs3034891 uc001zok.3 MAPKBP1_uc001zo... Hybrid_Cap...
MSH3 p.PPA66del 5 79950742 79950750 NCIH1341_LUNG 37 In_Frame_Del Del CCCCC... - rs60484572;rs1047489 uc003kgz.2 DHFR_uc011ctl.1... Hybrid_Cap...
MTUS2 p.T814K 13 29608227 29608227 NCIH1341_LUNG 37 Missense_Mutation SNP C A uc001usl.3 Hybrid_Cap... view
MYLK 3 123332875 123332876 NCIH1341_LUNG 37 3'UTR Ins - T rs35930843;rs115544676 uc003ego.2 MYLK_uc003egl.2... Hybrid_Cap...
MYLK3 p.K35E 16 46782003 46782003 NCIH1341_LUNG 37 Missense_Mutation SNP T C uc002eei.3 MYLK3_uc010vge.... Hybrid_Cap... view
NAV3 p.R1250_splice 12 78515718 78515718 NCIH1341_LUNG 37 Splice_Site_SNP SNP A T uc001syp.2 NAV3_uc001syo.2... Hybrid_Cap... view
NCAM1 11 112832307 112832308 NCIH1341_LUNG 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 NCIH1341_LUNG 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 NCIH1341_LUNG 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NEK9 14 75572824 75572824 NCIH1341_LUNG 37 Intron SNP C T uc001xrl.2 NEK9_uc001xrk.2... Hybrid_Cap... view
NFATC1 18 77287653 77287654 NCIH1341_LUNG 37 3'UTR Del AA - uc010xfg.1 NFATC1_uc002lnd... Hybrid_Cap...
NFIA 1 61921185 61921186 NCIH1341_LUNG 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NOTCH4 6 32170465 32170465 NCIH1341_LUNG 37 Intron Del G - uc003obb.2 NOTCH4_uc003oba... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 NCIH1341_LUNG 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
PAX3 2 223158653 223158653 NCIH1341_LUNG 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAX5 9 37034095 37034095 NCIH1341_LUNG 37 5'UTR Del C - uc003zzo.1 PAX5_uc011lpw.1... Hybrid_Cap...
PEX5L p.N547K 3 179525497 179525497 NCIH1341_LUNG 37 Missense_Mutation SNP G T uc003fki.1 PEX5L_uc011bqd.... Hybrid_Cap... view
PGGT1B 5 114548071 114548072 NCIH1341_LUNG 37 3'UTR Ins - C uc003kqw.3 PGGT1B_uc003kqx... Hybrid_Cap...
PIK3C2B p.G750S 1 204418411 204418411 NCIH1341_LUNG 37 Missense_Mutation SNP C T rs114917235 uc001haw.2 PIK3C2B_uc010pq... Hybrid_Cap... view
PIK3C2G p.P129del 12 18435399 18435401 NCIH1341_LUNG 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PIK3CA p.E542K 3 178936082 178936082 NCIH1341_LUNG 37 Missense_Mutation SNP G A uc003fjk.2 Hybrid_Cap... view
PKN2 p.L384del 1 89250482 89250484 NCIH1341_LUNG 37 In_Frame_Del Del TCT - uc001dmn.2 PKN2_uc001dmm.1... Hybrid_Cap...
PMS1 2 190670539 190670540 NCIH1341_LUNG 37 Intron Ins - A rs3214425 uc002urh.3 PMS1_uc010zga.1... Hybrid_Cap...
PMS2 p.C297S 7 6035178 6035178 NCIH1341_LUNG 37 Missense_Mutation SNP C G uc003spl.2 PMS2_uc003spj.2... Hybrid_Cap... view
POU5F1B p.G77fs 8 128428340 128428340 NCIH1341_LUNG 37 Frame_Shift_Del Del G - uc003ysf.2 LOC727677_uc003... Hybrid_Cap...
PPP3R1 p.F15_splice 2 68415824 68415824 NCIH1341_LUNG 37 Splice_Site_SNP SNP T A uc002sei.1 Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 NCIH1341_LUNG 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PTK6 20 62160740 62160740 NCIH1341_LUNG 37 3'UTR SNP T C uc002yfg.2 PTK6_uc011aay.1... Hybrid_Cap... view
PTPN22 p.G632_splice 1 114377062 114377062 NCIH1341_LUNG 37 Splice_Site_SNP SNP C A uc001eds.2 PTPN22_uc009wgq... Hybrid_Cap... view
RASGRF1 15 79277150 79277151 NCIH1341_LUNG 37 Intron Ins - C rs67045840;rs77640668 uc002beq.2 RASGRF1_uc002be... Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 NCIH1341_LUNG 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RPS6KA5 14 91360733 91360734 NCIH1341_LUNG 37 Intron Ins - T rs77438853 uc001xys.2 RPS6KA5_uc010tw... Hybrid_Cap...
RPS6KL1 14 75373626 75373627 NCIH1341_LUNG 37 3'UTR Ins - TGAT uc001xqx.1 RPS6KL1_uc001xq... Hybrid_Cap...
RUNX1T1 p.R42L 8 93029588 93029588 NCIH1341_LUNG 37 Missense_Mutation SNP C A uc011lgi.1 RUNX1T1_uc003yf... Hybrid_Cap... view
SETDB1 p.KSTRGFAL1162del 1 150936032 150936055 NCIH1341_LUNG 37 In_Frame_Del Del AAATC... - uc001evu.2 SETDB1_uc001evv... Hybrid_Cap...
SLC6A8 X 152957656 152957657 NCIH1341_LUNG 37 Intron Ins - A uc004fib.3 SLC6A8_uc004fic... Hybrid_Cap...
STK25 2 242435659 242435662 NCIH1341_LUNG 37 Intron Del AAGG - rs3215138;rs75497042 uc002wbm.2 STK25_uc002wbk.... Hybrid_Cap...
STK31 7 23872024 23872025 NCIH1341_LUNG 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TAOK1 p.R413K 17 27829641 27829641 NCIH1341_LUNG 37 Missense_Mutation SNP G A uc002hdz.1 TAOK1_uc010wbe.... Hybrid_Cap... view
TEC 4 48139307 48139310 NCIH1341_LUNG 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TGFB2 1 218519928 218519929 NCIH1341_LUNG 37 5'UTR Ins - AAAC uc001hln.2 TGFB2_uc001hll.... Hybrid_Cap...
TNFRSF18 p.R141* 1 1139318 1139318 NCIH1341_LUNG 37 Nonsense_Mutation SNP G A uc001add.2 TNFRSF18_uc001a... Hybrid_Cap... view
TP63 3 189507518 189507519 NCIH1341_LUNG 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TSSK2 p.A24T 22 19118982 19118982 NCIH1341_LUNG 37 Missense_Mutation SNP G A uc002zow.2 DGCR14_uc002zot... Hybrid_Cap... view
TSSK3 p.D42H 1 32828426 32828426 NCIH1341_LUNG 37 Missense_Mutation SNP G C uc001bvf.2 Hybrid_Cap... view
TTN p.K4194R 2 179597590 179597590 NCIH1341_LUNG 37 Missense_Mutation SNP T C uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 NCIH1341_LUNG 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
WIF1 p.V133_splice 12 65462686 65462686 NCIH1341_LUNG 37 Splice_Site_SNP SNP T A uc001ssk.2 Hybrid_Cap... view