Annotation Summary for Cell Line: NCI-H1355  

Cell line primary name: NCI-H1355
Cell line aliases: H1355
Gender: M
Site Primary: lung
Histology: carcinoma
Hist Subtype1: adenocarcinoma
Notes:
Source: ATCC
Expression arrays: CASED_p_NCLE_RNA4_HG-U133_Plus_2_H09_383782
SNP arrays: LOBBY_p_NCLE_DNAAffy6_GenomeWideSNP_6_C04_437326
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in NCI-H1355

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 NCIH1355_LUNG 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ADAM28 8 24211994 24211997 NCIH1355_LUNG 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 NCIH1355_LUNG 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 NCIH1355_LUNG 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ALPK2 p.R121S 18 56247645 56247645 NCIH1355_LUNG 37 Missense_Mutation SNP C A uc002lhj.3 Hybrid_Cap... view
ARAF p.A205D X 47426094 47426094 NCIH1355_LUNG 37 Missense_Mutation SNP C A uc011mlq.1 ARAF_uc011mln.1... Hybrid_Cap... view
C17ORF37 17 37885640 37885641 NCIH1355_LUNG 37 3'UTR Ins - G rs75811535 uc002hsq.2 Hybrid_Cap...
CACNA1F p.815_815E>EE X 49076224 49076225 NCIH1355_LUNG 37 In_Frame_Ins Ins - TCC uc004dnb.2 CACNA1F_uc010ni... Hybrid_Cap...
CDC5L p.P462S 6 44390526 44390526 NCIH1355_LUNG 37 Missense_Mutation SNP C T uc003oxl.2 Hybrid_Cap... view
CDC5L p.A632_splice 6 44397449 44397449 NCIH1355_LUNG 37 Splice_Site_SNP SNP G T uc003oxl.2 Hybrid_Cap... view
CDK12 p.K591E 17 37627856 37627856 NCIH1355_LUNG 37 Missense_Mutation SNP A G uc010cvv.2 CDK12_uc010wef.... Hybrid_Cap... view
CDK18 1 205495890 205495891 NCIH1355_LUNG 37 Intron Del CT - uc001hcr.2 CDK18_uc010pri.... Hybrid_Cap...
CDKL3 5 133541415 133541419 NCIH1355_LUNG 37 3'UTR Del TTTTG - uc011cxm.1 PPP2CA_uc003kze... Hybrid_Cap...
CHD5 p.K52N 1 6228261 6228261 NCIH1355_LUNG 37 Missense_Mutation SNP T A uc001amb.1 Hybrid_Cap... view
CHIC2 4 54876121 54876122 NCIH1355_LUNG 37 3'UTR Ins - A rs34881525 uc003haj.1 PDGFRA_uc003haa... Hybrid_Cap...
CNTN5 p.T686T 11 100126544 100126544 NCIH1355_LUNG 37 Silent SNP G T uc001pga.2 CNTN5_uc001pfz.... Hybrid_Cap... view
CNTN6 3 1339681 1339686 NCIH1355_LUNG 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
COL3A1 p.G675C 2 189864011 189864011 NCIH1355_LUNG 37 Missense_Mutation SNP G T uc002uqj.1 Hybrid_Cap... view
CREB3L2 p.T100del 7 137612914 137612916 NCIH1355_LUNG 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CSMD3 p.L958Q 8 113668514 113668514 NCIH1355_LUNG 37 Missense_Mutation SNP A T uc003ynu.2 CSMD3_uc003yns.... Hybrid_Cap... view
CSNK1E p.D110Y 22 38698874 38698874 NCIH1355_LUNG 37 Missense_Mutation SNP C A uc003avj.2 CSNK1E_uc003avk... Hybrid_Cap... view
CTBP2 p.K974fs 10 126678123 126678123 NCIH1355_LUNG 37 Frame_Shift_Del Del T - uc001lie.3 CTBP2_uc009yak.... Hybrid_Cap...
CUBN p.E980* 10 17110133 17110133 NCIH1355_LUNG 37 Nonsense_Mutation SNP C A uc001ioo.2 Hybrid_Cap... view
CXCL12 10 44873992 44873993 NCIH1355_LUNG 37 Intron Ins - CT rs117617571 uc001jbh.2 CXCL12_uc001jbf... Hybrid_Cap...
DACH1 p.G501R 13 72131225 72131225 NCIH1355_LUNG 37 Missense_Mutation SNP C T uc010thn.1 DACH1_uc010tho.... Hybrid_Cap... view
DDR2 1 162750211 162750212 NCIH1355_LUNG 37 3'UTR Del TT - uc001gcf.2 DDR2_uc001gcg.2... Hybrid_Cap...
DGKB 7 14188722 14188722 NCIH1355_LUNG 37 3'UTR SNP C T uc003ssz.2 DGKB_uc011jxt.1... Hybrid_Cap... view
DIABLO p.W7R 12 122710543 122710543 NCIH1355_LUNG 37 Missense_Mutation SNP A T uc010tab.1 DIABLO_uc010taa... Hybrid_Cap... view
DNAH8 6 38952247 38952250 NCIH1355_LUNG 37 Intron Del CACA - uc003ooe.1 DNAH8_uc003oog.... Hybrid_Cap...
DYRK1A 21 38884966 38884967 NCIH1355_LUNG 37 3'UTR Ins - T rs72430212 uc002ywk.2 DYRK1A_uc002ywi... Hybrid_Cap...
EGFR p.Q1159H 7 55273154 55273154 NCIH1355_LUNG 37 Missense_Mutation SNP G C uc003tqk.2 EGFR_uc011kco.1... Hybrid_Cap... view
EIF2AK4 p.Q953E 15 40289255 40289255 NCIH1355_LUNG 37 Missense_Mutation SNP C G uc001zkm.1 EIF2AK4_uc010bb... Hybrid_Cap... view
ERG p.M125I 21 39795366 39795366 NCIH1355_LUNG 37 Missense_Mutation SNP C T uc010gnw.2 ERG_uc002yxa.2_... Hybrid_Cap... view
ETV1 7 14028708 14028708 NCIH1355_LUNG 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
EXT1 8 118811807 118811807 NCIH1355_LUNG 37 3'UTR Del T - uc003yok.1 Hybrid_Cap...
FLI1 11 128638217 128638217 NCIH1355_LUNG 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FMN2 p.PPLPGAGIPPP939del 1 240370914 240370946 NCIH1355_LUNG 37 In_Frame_Del Del GCCCC... - rs4997328;rs4997329 uc010pye.1 FMN2_uc010pyd.1... Hybrid_Cap...
GLI2 2 121554895 121554895 NCIH1355_LUNG 37 5'UTR SNP A T uc010flp.2 GLI2_uc010yyu.1... Hybrid_Cap... view
GRIA3 X 122318386 122318387 NCIH1355_LUNG 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
HDAC4 2 240011625 240011625 NCIH1355_LUNG 37 Intron SNP C A uc002vyk.3 HDAC4_uc010fyz.... Hybrid_Cap... view
HNF1A 12 121434630 121434631 NCIH1355_LUNG 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
INHBA p.T361K 7 41729447 41729447 NCIH1355_LUNG 37 Missense_Mutation SNP G T uc003thq.2 INHBA_uc003thr.... Hybrid_Cap... view
INPP4B p.T840N 4 143003307 143003307 NCIH1355_LUNG 37 Missense_Mutation SNP G T uc003iix.3 INPP4B_uc003iiw... Hybrid_Cap... view
ITGA5 p.L561M 12 54797504 54797504 NCIH1355_LUNG 37 Missense_Mutation SNP G T uc001sga.2 Hybrid_Cap... view
KRAS p.G13C 12 25398282 25398282 NCIH1355_LUNG 37 Missense_Mutation SNP C A uc001rgp.1 KRAS_uc001rgq.1... Hybrid_Cap... view
LMTK3 p.E1007K 19 49001394 49001394 NCIH1355_LUNG 37 Missense_Mutation SNP C T uc002pjk.2 Hybrid_Cap... view
MAP3K1 p.T949del 5 56177849 56177851 NCIH1355_LUNG 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K2 p.A607T 2 128065196 128065196 NCIH1355_LUNG 37 Missense_Mutation SNP C T uc002toj.1 Hybrid_Cap... view
MAPKAPK3 3 50685575 50685575 NCIH1355_LUNG 37 3'UTR Del A - rs76026164 uc003day.1 MAPKAPK3_uc003d... Hybrid_Cap...
MCM3APAS 21 47671275 47671276 NCIH1355_LUNG 37 3'UTR Ins - AAT rs67797185 uc002zin.2 MCM3APAS_uc002z... Hybrid_Cap...
MKRN3 p.G178C 15 23811461 23811461 NCIH1355_LUNG 37 Missense_Mutation SNP G T uc001ywh.3 MKRN3_uc001ywi.... Hybrid_Cap... view
MLL3 p.V4115F 7 151849973 151849973 NCIH1355_LUNG 37 Missense_Mutation SNP C A uc003wla.2 MLL3_uc003wkz.2... Hybrid_Cap... view
MSH3 p.PPA66del 5 79950742 79950750 NCIH1355_LUNG 37 In_Frame_Del Del CCCCC... - rs60484572;rs1047489 uc003kgz.2 DHFR_uc011ctl.1... Hybrid_Cap...
MYH11 p.Q1462_splice 16 15818017 15818017 NCIH1355_LUNG 37 Splice_Site_SNP SNP C G rs112669844 uc002ddx.2 MYH11_uc002ddv.... Hybrid_Cap... view
NCAM1 11 112832307 112832308 NCIH1355_LUNG 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 NCIH1355_LUNG 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NEK1 4 170476823 170476823 NCIH1355_LUNG 37 Intron SNP C T uc003isd.1 NEK1_uc003isb.1... Hybrid_Cap... view
NLK p.I265V 17 26490610 26490610 NCIH1355_LUNG 37 Missense_Mutation SNP A G uc010crj.2 NLK_uc010cri.1_... Hybrid_Cap... view
NPM1 5 170837734 170837734 NCIH1355_LUNG 37 3'UTR Del T - uc011dex.1 NPM1_uc003mbi.2... Hybrid_Cap...
NPR1 1 153665919 153665920 NCIH1355_LUNG 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
PAX3 2 223158653 223158653 NCIH1355_LUNG 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PDE4DIP 1 144892096 144892096 NCIH1355_LUNG 37 Intron SNP G A uc001elw.3 NBPF10_uc009wir... Hybrid_Cap... view
PDGFRA 4 55161524 55161524 NCIH1355_LUNG 37 3'UTR SNP G C uc003han.3 PDGFRA_uc003haa... Hybrid_Cap... view
PDK4 7 95214895 95214895 NCIH1355_LUNG 37 3'UTR SNP G A uc003uoa.2 PDK4_uc003unz.2... Hybrid_Cap... view
PGR 11 100933598 100933599 NCIH1355_LUNG 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PIP4K2A p.W43L 10 23003128 23003128 NCIH1355_LUNG 37 Missense_Mutation SNP C A uc001irl.3 Hybrid_Cap... view
PNMT p.R44C 17 37824858 37824858 NCIH1355_LUNG 37 Missense_Mutation SNP C T uc002hsi.1 Hybrid_Cap... view
PRKCB p.D475Y 16 24192139 24192139 NCIH1355_LUNG 37 Missense_Mutation SNP G T uc002dme.2 PRKCB_uc002dmd.... Hybrid_Cap... view
PTCH2 p.R561L 1 45293995 45293995 NCIH1355_LUNG 37 Missense_Mutation SNP C A uc010olf.1 PTCH2_uc010olg.... Hybrid_Cap... view
RAG1 p.K976E 11 36597780 36597780 NCIH1355_LUNG 37 Missense_Mutation SNP A G uc001mwu.3 RAG1_uc001mwt.2... Hybrid_Cap... view
RASGRF1 15 79277150 79277151 NCIH1355_LUNG 37 Intron Ins - C rs67045840;rs77640668 uc002beq.2 RASGRF1_uc002be... Hybrid_Cap...
RET p.L712_splice 10 43610185 43610185 NCIH1355_LUNG 37 Splice_Site_SNP SNP G T uc001jal.2 RET_uc001jak.1_... Hybrid_Cap... view
RIOK2 p.T328I 5 96503585 96503585 NCIH1355_LUNG 37 Missense_Mutation SNP G A uc003kmz.2 RIOK2_uc003kna.... Hybrid_Cap... view
ROBO2 3 77089806 77089806 NCIH1355_LUNG 37 5'UTR SNP C A uc003dpz.2 ROBO2_uc003dpy.... Hybrid_Cap... view
ROBO2 p.W351L 3 77595594 77595594 NCIH1355_LUNG 37 Missense_Mutation SNP G T uc003dpz.2 ROBO2_uc003dpy.... Hybrid_Cap... view
ROCK2 p.M859I 2 11342220 11342220 NCIH1355_LUNG 37 Missense_Mutation SNP C A uc002rbd.1 Hybrid_Cap... view
RPS6KB1 17 58024224 58024225 NCIH1355_LUNG 37 3'UTR Ins - AA rs67846207 uc002ixy.2 RPS6KB1_uc010dd... Hybrid_Cap...
SCD5 4 83552278 83552279 NCIH1355_LUNG 37 3'UTR Ins - A rs72177305 uc003hna.2 Hybrid_Cap...
STAT1 2 191840353 191840353 NCIH1355_LUNG 37 Intron Del T - uc002usj.2 STAT1_uc010fse.... Hybrid_Cap...
STIL p.S1086W 1 47717418 47717418 NCIH1355_LUNG 37 Missense_Mutation SNP G C uc001crd.1 TAL1_uc001crb.1... Hybrid_Cap... view
STK31 7 23872024 23872025 NCIH1355_LUNG 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TAB2 p.D663N 6 149730760 149730760 NCIH1355_LUNG 37 Missense_Mutation SNP G A uc003qmj.2 TAB2_uc011eec.1... Hybrid_Cap... view
TAOK2 p.E399del 16 29994531 29994533 NCIH1355_LUNG 37 In_Frame_Del Del GAG - uc010bzm.1 BOLA2_uc010bzb.... Hybrid_Cap...
TAOK2 p.S493F 16 29996568 29996568 NCIH1355_LUNG 37 Missense_Mutation SNP C T uc010bzm.1 BOLA2_uc010bzb.... Hybrid_Cap... view
TGFB3 14 76447334 76447334 NCIH1355_LUNG 37 5'UTR SNP C T uc001xsc.2 TGFB3_uc001xsd.... Hybrid_Cap... view
TNNI3K p.A774V 1 74929131 74929131 NCIH1355_LUNG 37 Missense_Mutation SNP C T uc001dge.1 TNNI3K_uc001dgd... Hybrid_Cap... view
TP53 p.E285K 17 7577085 7577085 NCIH1355_LUNG 37 Missense_Mutation SNP C T rs112431538 uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TRIM33 1 114940215 114940216 NCIH1355_LUNG 37 3'UTR Ins - G rs68133208 uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TSHR 14 81610974 81610974 NCIH1355_LUNG 37 3'UTR SNP C A uc001xvd.1 Hybrid_Cap... view
TTN p.C30841Y 2 179401248 179401248 NCIH1355_LUNG 37 Missense_Mutation SNP C T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.K10720N 2 179516394 179516394 NCIH1355_LUNG 37 Missense_Mutation SNP T A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN 2 179621171 179621171 NCIH1355_LUNG 37 Intron SNP G C uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TXK p.K88N 4 48114440 48114440 NCIH1355_LUNG 37 Missense_Mutation SNP C G uc003gxx.3 TXK_uc003gxy.1_... Hybrid_Cap... view
WHSC1 p.L761I 4 1955194 1955194 NCIH1355_LUNG 37 Missense_Mutation SNP C A uc003gdz.3 WHSC1_uc003geb.... Hybrid_Cap... view