Annotation Summary for Cell Line: NCI-H1650  

Cell line primary name: NCI-H1650
Cell line aliases: H1650
Gender: M
Site Primary: lung
Histology: carcinoma
Hist Subtype1: bronchioloalveolar_adenocarcinoma
Notes:
Source: ATCC
Expression arrays: CASED_p_NCLE_RNA4_HG-U133_Plus_2_B09_383752
SNP arrays: FIEFS_p_NCLE_DNA_Affy5_GenomeWideSNP_6_B06_410890
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in NCI-H1650

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ABCA3 16 2339311 2339311 NCIH1650_LUNG 37 Intron SNP G A uc002cpy.1 ABCA3_uc010bsk.... Hybrid_Cap... view
ACACA 17 35766564 35766564 NCIH1650_LUNG 37 5'UTR Del A - uc002hno.2 ACACA_uc002hnn.... Hybrid_Cap...
ADAM17 2 9630245 9630245 NCIH1650_LUNG 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 NCIH1650_LUNG 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADAM29 p.L691del 4 175898744 175898746 NCIH1650_LUNG 37 In_Frame_Del Del TTA - uc003iuc.2 ADAM29_uc003iud... Hybrid_Cap...
ADAMTS2 p.E635K 5 178564818 178564818 NCIH1650_LUNG 37 Missense_Mutation SNP C T uc003mjw.2 Hybrid_Cap... view
AKAP12 p.1531_1532insE 6 151674116 151674117 NCIH1650_LUNG 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ALPK1 4 113347609 113347610 NCIH1650_LUNG 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 NCIH1650_LUNG 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
AURKC 19 57742494 57742507 NCIH1650_LUNG 37 5'UTR Del GGACG... - rs67926438;rs112039303;rs59094959 uc002qoe.2 AURKC_uc002qoc.... Hybrid_Cap...
BCR 22 23631813 23631814 NCIH1650_LUNG 37 Intron Ins - C rs66503844 uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BCR 22 23632777 23632778 NCIH1650_LUNG 37 Intron Ins - T uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
CABC1 1 227171736 227171737 NCIH1650_LUNG 37 Intron Ins - T rs1574184 uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CACNB2 10 18828721 18828722 NCIH1650_LUNG 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CARD10 p.KE272del 22 37906309 37906314 NCIH1650_LUNG 37 In_Frame_Del Del CTCCT... - uc003asx.1 CARD10_uc003ast... Hybrid_Cap...
CCR5 3 46415525 46415525 NCIH1650_LUNG 37 3'UTR SNP G A uc003cpo.3 CCR5_uc010hjd.2... Hybrid_Cap... view
CDK11B p.E107* 1 1650803 1650803 NCIH1650_LUNG 37 Nonsense_Mutation SNP C A uc001agv.1 CDK11B_uc001ags... Hybrid_Cap... view
CIITA p.E372D 16 11000462 11000462 NCIH1650_LUNG 37 Missense_Mutation SNP G C uc002daj.3 CIITA_uc002dai.... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 NCIH1650_LUNG 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN6 3 1339681 1339686 NCIH1650_LUNG 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
CREB3L2 p.T100del 7 137612914 137612916 NCIH1650_LUNG 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CRP p.R206W 1 159683374 159683374 NCIH1650_LUNG 37 Missense_Mutation SNP G A uc001ftw.2 CRP_uc001ftx.1_... Hybrid_Cap... view
CSF1R 5 149433400 149433401 NCIH1650_LUNG 37 3'UTR Ins - C rs66970099;rs78449650 uc003lrl.2 CSF1R_uc011dcd.... Hybrid_Cap...
DFNA5 p.S23L 7 24789326 24789326 NCIH1650_LUNG 37 Missense_Mutation SNP G A uc010kus.1 DFNA5_uc003swz.... Hybrid_Cap... view
EDNRA p.S289I 4 148457147 148457147 NCIH1650_LUNG 37 Missense_Mutation SNP G T uc003iky.2 EDNRA_uc011cid.... Hybrid_Cap... view
EGF 4 110834446 110834446 NCIH1650_LUNG 37 5'UTR SNP G A uc003hzy.3 EGF_uc011cfu.1_... Hybrid_Cap... view
EGFR p.ELREA746del 7 55242465 55242479 NCIH1650_LUNG 37 In_Frame_Del Del GGAAT... - uc003tqk.2 EGFR_uc010kzg.1... Hybrid_Cap...
EIF4E 4 99808137 99808141 NCIH1650_LUNG 37 Intron Del TTAAA - uc011ceb.1 EIF4E_uc011cea.... Hybrid_Cap...
ERG p.K96R 21 39795454 39795454 NCIH1650_LUNG 37 Missense_Mutation SNP T C uc010gnw.2 ERG_uc002yxa.2_... Hybrid_Cap... view
ETV1 7 14028708 14028708 NCIH1650_LUNG 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
EXT1 8 118811807 118811807 NCIH1650_LUNG 37 3'UTR Del T - uc003yok.1 Hybrid_Cap...
FANCD2 3 10143061 10143061 NCIH1650_LUNG 37 3'UTR SNP C T uc003bux.1 FANCD2_uc003buy... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 NCIH1650_LUNG 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 NCIH1650_LUNG 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLT4 5 180035183 180035185 NCIH1650_LUNG 37 Intron Del AGT - uc003mlz.3 FLT4_uc003mma.3... Hybrid_Cap...
FMN2 p.PPLPGAGIPPP939del 1 240370914 240370946 NCIH1650_LUNG 37 In_Frame_Del Del GCCCC... - rs4997328;rs4997329 uc010pye.1 FMN2_uc010pyd.1... Hybrid_Cap...
FN1 2 216244182 216244185 NCIH1650_LUNG 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GRIA3 X 122318386 122318387 NCIH1650_LUNG 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 NCIH1650_LUNG 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HIF1A 14 62213929 62213930 NCIH1650_LUNG 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HNF1A 12 121434630 121434631 NCIH1650_LUNG 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
ID1 20 30193778 30193778 NCIH1650_LUNG 37 Intron SNP C T uc002wwg.1 ID1_uc002wwh.1_... Hybrid_Cap... view
ILK 11 6630029 6630029 NCIH1650_LUNG 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 NCIH1650_LUNG 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
JAG2 p.R58H 14 105634338 105634338 NCIH1650_LUNG 37 Missense_Mutation SNP C T uc001yqg.2 JAG2_uc001yqh.2... Hybrid_Cap... view
KLK7 19 51480672 51480675 NCIH1650_LUNG 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
MAF 16 79628537 79628537 NCIH1650_LUNG 37 Intron Del T - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 NCIH1650_LUNG 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 NCIH1650_LUNG 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 NCIH1650_LUNG 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAP3K7 6 91246267 91246268 NCIH1650_LUNG 37 Intron Ins - A rs114677180 uc003pnz.1 MAP3K7_uc003pny... Hybrid_Cap...
MAPKAPK3 3 50685575 50685575 NCIH1650_LUNG 37 3'UTR Del A - rs76026164 uc003day.1 MAPKAPK3_uc003d... Hybrid_Cap...
MAPKBP1 15 42111753 42111754 NCIH1650_LUNG 37 Intron Ins - C rs3034891 uc001zok.3 MAPKBP1_uc001zo... Hybrid_Cap...
MAST4 p.S1913R 5 66461311 66461311 NCIH1650_LUNG 37 Missense_Mutation SNP A C uc003jut.1 MAST4_uc003juw.... Hybrid_Cap... view
MCM3APAS 21 47671275 47671276 NCIH1650_LUNG 37 3'UTR Ins - AAT rs67797185 uc002zin.2 MCM3APAS_uc002z... Hybrid_Cap...
MECOM 3 169381262 169381262 NCIH1650_LUNG 37 5'UTR SNP G C rs10581416 uc011bpj.1 MECOM_uc011bpk.... Hybrid_Cap... view
MYH1 p.I1609N 17 10399697 10399697 NCIH1650_LUNG 37 Missense_Mutation SNP A T uc002gmo.2 Hybrid_Cap... view
MYST4 p.E1104del 10 76781906 76781908 NCIH1650_LUNG 37 In_Frame_Del Del GAA - rs79644703 uc001jwn.1 MYST4_uc001jwm.... Hybrid_Cap...
NCAM1 11 112832307 112832308 NCIH1650_LUNG 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 NCIH1650_LUNG 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 p.T272_splice 11 113102366 113102366 NCIH1650_LUNG 37 Splice_Site_SNP SNP G T uc009yyq.1 Hybrid_Cap... view
NCOA3 p.QQQ1272del 20 46279815 46279823 NCIH1650_LUNG 37 In_Frame_Del Del GCAGC... - uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NFIA 1 61921185 61921186 NCIH1650_LUNG 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NOTCH4 p.15_16LL>L 6 32191659 32191661 NCIH1650_LUNG 37 In_Frame_Del Del AGC - uc003obb.2 NOTCH4_uc011dpu... Hybrid_Cap...
NPM1 5 170837734 170837734 NCIH1650_LUNG 37 3'UTR Del T - uc011dex.1 NPM1_uc003mbi.2... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 NCIH1650_LUNG 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NUP98 11 3733612 3733618 NCIH1650_LUNG 37 Intron Del AGTAA... - uc001lyh.2 NUP98_uc001lyi.... Hybrid_Cap...
OMG p.C11Y 17 29623318 29623318 NCIH1650_LUNG 37 Missense_Mutation SNP C T uc002hgj.2 NF1_uc002hgg.2_... Hybrid_Cap... view
P2RX7 12 121622616 121622616 NCIH1650_LUNG 37 3'UTR SNP C T uc001tzm.2 P2RX7_uc001tzn.... Hybrid_Cap... view
PAX3 2 223158653 223158653 NCIH1650_LUNG 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PCDH15 p.L386V 10 55955607 55955607 NCIH1650_LUNG 37 Missense_Mutation SNP G C uc010qhy.1 PCDH15_uc010qhq... Hybrid_Cap... view
PDE4DIP 1 144930732 144930732 NCIH1650_LUNG 37 Intron SNP G A uc001elw.3 NBPF10_uc009wir... Hybrid_Cap... view
PGR 11 100933598 100933599 NCIH1650_LUNG 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PIK3C2A p.C1524R 11 17113615 17113615 NCIH1650_LUNG 37 Missense_Mutation SNP A G uc001mmq.3 PIK3C2A_uc009yg... Hybrid_Cap... view
PIK3C2G p.P129del 12 18435399 18435401 NCIH1650_LUNG 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 NCIH1650_LUNG 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
RASGRF1 p.A1001V 15 79290450 79290450 NCIH1650_LUNG 37 Missense_Mutation SNP G A uc002beq.2 RASGRF1_uc002be... Hybrid_Cap... view
RBPJ p.R238* 4 26426291 26426291 NCIH1650_LUNG 37 Nonsense_Mutation SNP C T rs5007634 uc003grx.1 RBPJ_uc003gry.1... Hybrid_Cap... view
RECQL4 p.R766fs 8 145738768 145738768 NCIH1650_LUNG 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
ROBO2 3 77666937 77666937 NCIH1650_LUNG 37 Intron Del A - rs78745603 uc003dpz.2 ROBO2_uc003dpy.... Hybrid_Cap...
SBDS p.I133V 7 66458266 66458266 NCIH1650_LUNG 37 Missense_Mutation SNP T C uc003tvm.1 Hybrid_Cap... view
SLC6A8 X 152957656 152957657 NCIH1650_LUNG 37 Intron Ins - A uc004fib.3 SLC6A8_uc004fic... Hybrid_Cap...
SMARCA4 p.N1164Y 19 11141513 11141513 NCIH1650_LUNG 37 Missense_Mutation SNP A T uc010dxo.2 SMARCA4_uc002mq... Hybrid_Cap... view
SPRY2 13 80910853 80910853 NCIH1650_LUNG 37 3'UTR SNP G A uc001vli.2 SPRY2_uc001vlj.... Hybrid_Cap... view
STAT1 2 191840353 191840353 NCIH1650_LUNG 37 Intron Del T - uc002usj.2 STAT1_uc010fse.... Hybrid_Cap...
STK31 7 23872024 23872025 NCIH1650_LUNG 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
SULF1 p.M216I 8 70501290 70501290 NCIH1650_LUNG 37 Missense_Mutation SNP G A uc010lza.1 SULF1_uc003xyd.... Hybrid_Cap... view
TCF21 6 134210497 134210498 NCIH1650_LUNG 37 5'UTR Ins - TCTC rs35199378 uc003qei.3 TCF21_uc003qej.... Hybrid_Cap...
TEC 4 48139307 48139310 NCIH1650_LUNG 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TMEM123 11 102269398 102269398 NCIH1650_LUNG 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TNRC6B p.Q1328del 22 40697177 40697179 NCIH1650_LUNG 37 In_Frame_Del Del GCA - rs114291931 uc011aor.1 TNRC6B_uc003aym... Hybrid_Cap...
TP53 p.V225_splice 17 7577610 7577610 NCIH1650_LUNG 37 Splice_Site_SNP SNP T C uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TRPS1 8 116635872 116635873 NCIH1650_LUNG 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TTN 2 179391639 179391640 NCIH1650_LUNG 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
VEGFC p.S419_splice 4 177605082 177605084 NCIH1650_LUNG 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...