Annotation Summary for Cell Line: NCI-H1781  

Cell line primary name: NCI-H1781
Cell line aliases: H1781
Gender: F
Site Primary: lung
Histology: carcinoma
Hist Subtype1: bronchioloalveolar_adenocarcinoma
Notes:
Source: ATCC
Expression arrays: NIECE_p_NCLE_RNA3_HG-U133_Plus_2_G04_296140
SNP arrays: FASTS_p_NCLE_DNAAffy4_S_GenomeWideSNP_6_C03_335240
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in NCI-H1781

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ADAM17 2 9630245 9630245 NCIH1781_LUNG 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 NCIH1781_LUNG 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 NCIH1781_LUNG 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP9 p.1335_1336insQ 7 91652178 91652179 NCIH1781_LUNG 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 NCIH1781_LUNG 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ALS2 2 202587706 202587707 NCIH1781_LUNG 37 Intron Ins - A rs3219165 uc002uyo.2 ALS2_uc002uyp.3... Hybrid_Cap...
ATR p.Y575C 3 142278101 142278101 NCIH1781_LUNG 37 Missense_Mutation SNP T C uc003eux.3 Hybrid_Cap... view
BAX 19 49464508 49464508 NCIH1781_LUNG 37 3'UTR Del T - uc002plf.1 BAX_uc002plg.1_... Hybrid_Cap...
C15ORF2 p.T617I 15 24922864 24922864 NCIH1781_LUNG 37 Missense_Mutation SNP C T uc001ywo.2 Hybrid_Cap... view
CACNB2 10 18828721 18828722 NCIH1781_LUNG 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CDC7 p.D526H 1 91989843 91989843 NCIH1781_LUNG 37 Missense_Mutation SNP G C uc001doe.2 CDC7_uc001dof.2... Hybrid_Cap... view
CDC73 p.R139Q 1 193104712 193104712 NCIH1781_LUNG 37 Missense_Mutation SNP G A uc001gtb.2 MIR1278_hsa-mir... Hybrid_Cap... view
CHD1 p.P1684del 5 98192165 98192167 NCIH1781_LUNG 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 NCIH1781_LUNG 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CSMD3 p.G499V 8 113960031 113960031 NCIH1781_LUNG 37 Missense_Mutation SNP C A uc003ynu.2 CSMD3_uc003ynt.... Hybrid_Cap... view
CXCL12 10 44873992 44873993 NCIH1781_LUNG 37 Intron Ins - CT rs117617571 uc001jbh.2 CXCL12_uc001jbf... Hybrid_Cap...
DACH1 13 72014625 72014626 NCIH1781_LUNG 37 3'UTR Ins - T rs117109529 uc010thn.1 DACH1_uc010tho.... Hybrid_Cap...
DYRK1A 21 38884966 38884967 NCIH1781_LUNG 37 3'UTR Ins - T rs72430212 uc002ywk.2 DYRK1A_uc002ywi... Hybrid_Cap...
ECM1 p.Y431F 1 150484949 150484949 NCIH1781_LUNG 37 Missense_Mutation SNP A T uc001euu.2 ECM1_uc001eus.2... Hybrid_Cap... view
EDN1 6 12290729 12290729 NCIH1781_LUNG 37 5'UTR Del A - uc003nae.3 EDN1_uc010jpb.2... Hybrid_Cap...
EP300 22 41574970 41574972 NCIH1781_LUNG 37 3'UTR Del GTA - rs76489032 uc003azl.3 Hybrid_Cap...
EPHA5 4 66189753 66189754 NCIH1781_LUNG 37 3'UTR Ins - T rs67487372 uc011cah.1 EPHA5_uc003hcx.... Hybrid_Cap...
EPHA6 3 97367230 97367231 NCIH1781_LUNG 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
EPHB1 p.N328I 3 134851577 134851577 NCIH1781_LUNG 37 Missense_Mutation SNP A T uc003eqt.2 EPHB1_uc010htz.... Hybrid_Cap... view
ERBB2 p.776_776G>VC 17 37880997 37880998 NCIH1781_LUNG 37 In_Frame_Ins Ins - TGT rs28933369 uc002hso.2 ERBB2_uc002hsm.... Hybrid_Cap...
FANCM p.D1139V 14 45645373 45645373 NCIH1781_LUNG 37 Missense_Mutation SNP A T uc001wwd.3 FANCM_uc010anf.... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 NCIH1781_LUNG 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 NCIH1781_LUNG 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLI1 11 128638217 128638217 NCIH1781_LUNG 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FMO4 p.I8T 1 171288987 171288987 NCIH1781_LUNG 37 Missense_Mutation SNP T C uc001gho.2 Hybrid_Cap... view
FN1 2 216244182 216244185 NCIH1781_LUNG 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
FNBP1 9 132658078 132658079 NCIH1781_LUNG 37 Intron Ins - T rs71738364 uc004byw.1 FNBP1_uc011mbv.... Hybrid_Cap...
FZD1 p.93_94insP 7 90894459 90894460 NCIH1781_LUNG 37 In_Frame_Ins Ins - CCG uc003ula.2 Hybrid_Cap...
GATA2 p.S464R 3 128199913 128199913 NCIH1781_LUNG 37 Missense_Mutation SNP G T uc003ekm.3 GATA2_uc003ekn.... Hybrid_Cap... view
GRIA3 X 122318386 122318387 NCIH1781_LUNG 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 NCIH1781_LUNG 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HIF1A 14 62213929 62213930 NCIH1781_LUNG 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HMGA2 12 66345301 66345301 NCIH1781_LUNG 37 3'UTR SNP G A uc001ssw.1 HMGA2_uc001ssx.... Hybrid_Cap... view
HNF1A 12 121434630 121434631 NCIH1781_LUNG 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
HSP90B1 p.R414C 12 104335416 104335416 NCIH1781_LUNG 37 Missense_Mutation SNP C T uc001tkb.1 HSP90B1_uc010sw... Hybrid_Cap... view
ILK 11 6630029 6630029 NCIH1781_LUNG 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
KDM5A p.E235Q 12 465673 465673 NCIH1781_LUNG 37 Missense_Mutation SNP C G uc001qif.1 KDM5A_uc001qie.... Hybrid_Cap... view
LCP1 13 46701614 46701614 NCIH1781_LUNG 37 3'UTR SNP T G uc001vaz.3 LCP1_uc010ack.2... Hybrid_Cap... view
LRP1B p.D2204E 2 141458006 141458006 NCIH1781_LUNG 37 Missense_Mutation SNP A T uc002tvj.1 Hybrid_Cap... view
LRP6 12 12419797 12419797 NCIH1781_LUNG 37 5'UTR SNP G A uc001rah.3 LRP6_uc010shl.1... Hybrid_Cap... view
MAF 16 79628537 79628537 NCIH1781_LUNG 37 Intron Del T - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 NCIH1781_LUNG 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 NCIH1781_LUNG 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 NCIH1781_LUNG 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MLH1 3 37092174 37092176 NCIH1781_LUNG 37 3'UTR Del TTC - uc003cgl.2 MLH1_uc011aye.1... Hybrid_Cap...
MLL3 p.D597H 7 151946985 151946985 NCIH1781_LUNG 37 Missense_Mutation SNP C G uc003wla.2 Hybrid_Cap... view
MLLT3 9 20346377 20346378 NCIH1781_LUNG 37 3'UTR Ins - A rs66943046 uc003zoe.2 MLLT3_uc011lne.... Hybrid_Cap...
MSH6 p.L1081F 2 48030629 48030629 NCIH1781_LUNG 37 Missense_Mutation SNP G T uc002rwd.3 MSH6_uc010fbj.2... Hybrid_Cap... view
MTUS2 13 30002822 30002822 NCIH1781_LUNG 37 Intron SNP C A rs112023852 uc001usl.3 MTUS2_uc001usm.... Hybrid_Cap... view
MYLK 3 123332876 123332876 NCIH1781_LUNG 37 3'UTR Del T - rs115544676 uc003ego.2 MYLK_uc003egl.2... Hybrid_Cap...
MYLK p.E1430_splice 3 123368043 123368044 NCIH1781_LUNG 37 Splice_Site_Ins Ins - G rs41431347 uc003ego.2 MYLK_uc010hrr.2... Hybrid_Cap...
NCAM1 11 112832307 112832308 NCIH1781_LUNG 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 NCIH1781_LUNG 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA3 p.Q1276del 20 46279837 46279839 NCIH1781_LUNG 37 In_Frame_Del Del CAG - rs2664555 uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 NCIH1781_LUNG 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NFIA 1 61921185 61921186 NCIH1781_LUNG 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NLRP3 p.S968I 1 247608015 247608015 NCIH1781_LUNG 37 Missense_Mutation SNP G T uc001icr.2 NLRP3_uc001ics.... Hybrid_Cap... view
NOTCH4 p.15_16LL>L 6 32191659 32191661 NCIH1781_LUNG 37 In_Frame_Del Del AGC - uc003obb.2 NOTCH4_uc011dpu... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 NCIH1781_LUNG 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NTRK3 p.P634T 15 88472655 88472655 NCIH1781_LUNG 37 Missense_Mutation SNP G T uc002bme.1 NTRK3_uc002bmh.... Hybrid_Cap... view
PAX3 2 223158653 223158653 NCIH1781_LUNG 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PDGFA p.R158H 7 550468 550468 NCIH1781_LUNG 37 Missense_Mutation SNP C T uc003sit.1 PDGFA_uc003sir.... Hybrid_Cap... view
PDZRN4 p.N317K 12 41961665 41961665 NCIH1781_LUNG 37 Missense_Mutation SNP T G uc010skn.1 PDZRN4_uc001rmq... Hybrid_Cap... view
PGR 11 100933598 100933599 NCIH1781_LUNG 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PIKFYVE p.I667M 2 209180091 209180091 NCIH1781_LUNG 37 Missense_Mutation SNP C G rs35180719 uc002vcz.2 PIKFYVE_uc010fu... Hybrid_Cap... view
PLCB2 p.T111S 15 40594711 40594711 NCIH1781_LUNG 37 Missense_Mutation SNP T A uc001zld.2 PLCB2_uc010bbo.... Hybrid_Cap... view
PREX2 8 69143713 69143713 NCIH1781_LUNG 37 3'UTR Del T - uc003xxv.1 Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 NCIH1781_LUNG 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PRKG1 10 52751071 52751079 NCIH1781_LUNG 37 5'UTR Del GCCGC... - uc001jjm.2 PRKG1_uc010qhp.... Hybrid_Cap...
PTEN p.Q245fs 10 89717710 89717714 NCIH1781_LUNG 37 Frame_Shift_Del Del GCCGT - uc001kfb.2 Hybrid_Cap...
PTPN22 p.E703A 1 114372597 114372597 NCIH1781_LUNG 37 Missense_Mutation SNP T G uc001eds.2 PTPN22_uc009wgq... Hybrid_Cap... view
RANBP17 p.G343R 5 170345789 170345789 NCIH1781_LUNG 37 Missense_Mutation SNP G A uc003mba.2 RANBP17_uc003ma... Hybrid_Cap... view
RANBP17 p.R356T 5 170345829 170345829 NCIH1781_LUNG 37 Missense_Mutation SNP G C uc003mba.2 RANBP17_uc003ma... Hybrid_Cap... view
RAPGEF2 4 160189200 160189201 NCIH1781_LUNG 37 5'UTR Ins - T rs72011511 uc003iqg.3 Hybrid_Cap...
RBM15 p.P864S 1 110884617 110884617 NCIH1781_LUNG 37 Missense_Mutation SNP C T uc001dzl.1 RBM15_uc001dzm.... Hybrid_Cap... view
RBPJ p.R238* 4 26426291 26426291 NCIH1781_LUNG 37 Nonsense_Mutation SNP C T rs5007634 uc003grx.1 RBPJ_uc003gry.1... Hybrid_Cap... view
RECQL4 p.R766fs 8 145738768 145738768 NCIH1781_LUNG 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RPS6KA5 14 91360733 91360734 NCIH1781_LUNG 37 Intron Ins - T rs77438853 uc001xys.2 RPS6KA5_uc010tw... Hybrid_Cap...
SCYL3 1 169822851 169822851 NCIH1781_LUNG 37 3'UTR SNP T C uc001ggs.2 SCYL3_uc010plw.... Hybrid_Cap... view
SOS1 p.E715Q 2 39240625 39240625 NCIH1781_LUNG 37 Missense_Mutation SNP C G uc002rrk.3 SOS1_uc002rrj.3... Hybrid_Cap... view
STK4 p.P242L 20 43625841 43625841 NCIH1781_LUNG 37 Missense_Mutation SNP C T uc002xnb.2 STK4_uc010ggx.2... Hybrid_Cap... view
TCF21 6 134210497 134210498 NCIH1781_LUNG 37 5'UTR Ins - TCTC rs35199378 uc003qei.3 TCF21_uc003qej.... Hybrid_Cap...
TET1 p.N2075Y 10 70451383 70451383 NCIH1781_LUNG 37 Missense_Mutation SNP A T uc001jok.3 Hybrid_Cap... view
TGFB2 1 218519928 218519929 NCIH1781_LUNG 37 5'UTR Ins - AAAC uc001hln.2 TGFB2_uc001hll.... Hybrid_Cap...
TMEM123 11 102269398 102269398 NCIH1781_LUNG 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TNFAIP3 p.M396L 6 138199768 138199768 NCIH1781_LUNG 37 Missense_Mutation SNP A T uc003qhr.2 TNFAIP3_uc003qh... Hybrid_Cap... view
TP53 p.V157F 17 7578461 7578461 NCIH1781_LUNG 37 Missense_Mutation SNP C A uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TP63 3 189507518 189507519 NCIH1781_LUNG 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TRPM6 9 77502981 77502981 NCIH1781_LUNG 37 5'UTR SNP G A uc004ajl.1 TRPM6_uc004ajk.... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 NCIH1781_LUNG 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
VPS13B p.G567E 8 100155250 100155250 NCIH1781_LUNG 37 Missense_Mutation SNP G A uc003yiv.2 VPS13B_uc003yiw... Hybrid_Cap... view
WRN p.Q1059E 8 30999233 30999233 NCIH1781_LUNG 37 Missense_Mutation SNP C G uc003xio.3 WRN_uc010lvk.2_... Hybrid_Cap... view