Annotation Summary for Cell Line: NCI-H1869  

Cell line primary name: NCI-H1869
Cell line aliases: H1869
Gender: M
Site Primary: lung
Histology: carcinoma
Hist Subtype1: squamous_cell_carcinoma
Notes:
Source: ATCC
Expression arrays: WATCH_p_NCLE_RNA8_HG-U133_Plus_2_A05_474768
SNP arrays: VAULT_p_NCLE_DNAAffy14_GenomeWideSNP_6_G02_698552
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in NCI-H1869

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AKAP12 p.1531_1532insE 6 151674116 151674117 NCIH1869_LUNG 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 NCIH1869_LUNG 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
AMHR2 p.R71W 12 53818233 53818233 NCIH1869_LUNG 37 Missense_Mutation SNP C T uc001scx.1 AMHR2_uc009zmy.... Hybrid_Cap... view
ARID1A p.G1847fs 1 27105930 27105931 NCIH1869_LUNG 37 Frame_Shift_Ins Ins - G uc001bmv.1 ARID1A_uc001bmu... Hybrid_Cap...
AURKC 19 57742494 57742507 NCIH1869_LUNG 37 5'UTR Del GGACG... - rs67926438;rs112039303;rs59094959 uc002qoe.2 AURKC_uc002qoc.... Hybrid_Cap...
BCR 22 23631813 23631814 NCIH1869_LUNG 37 Intron Ins - C rs66503844 uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
CACNB2 10 18828721 18828722 NCIH1869_LUNG 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CLTC p.Q628H 17 57743930 57743930 NCIH1869_LUNG 37 Missense_Mutation SNP G T uc002ixr.1 CLTC_uc002ixp.2... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 NCIH1869_LUNG 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CSMD3 p.W3279R 8 113275895 113275895 NCIH1869_LUNG 37 Missense_Mutation SNP A G uc003ynu.2 CSMD3_uc003yns.... Hybrid_Cap... view
CYFIP1 p.E155D 15 22929791 22929791 NCIH1869_LUNG 37 Missense_Mutation SNP A C uc001yus.2 CYFIP1_uc001yut... Hybrid_Cap... view
DDR2 1 162750052 162750052 NCIH1869_LUNG 37 3'UTR SNP G A uc001gcf.2 DDR2_uc001gcg.2... Hybrid_Cap... view
DLC1 p.E56D 8 13357413 13357413 NCIH1869_LUNG 37 Missense_Mutation SNP C A uc003wwm.2 DLC1_uc003wwn.2... Hybrid_Cap... view
DST 6 56483305 56483305 NCIH1869_LUNG 37 Intron SNP C T uc003pdf.2 DST_uc003pcz.3_... Hybrid_Cap... view
EP300 22 41574970 41574972 NCIH1869_LUNG 37 3'UTR Del GTA - rs76489032 uc003azl.3 Hybrid_Cap...
EPHA4 2 222436996 222436996 NCIH1869_LUNG 37 5'UTR SNP C T uc002vmq.2 EPHA4_uc002vmr.... Hybrid_Cap... view
EPHA6 3 97467610 97467611 NCIH1869_LUNG 37 3'UTR Ins - CT uc010how.1 Hybrid_Cap...
ERBB4 p.P1299L 2 212248371 212248371 NCIH1869_LUNG 37 Missense_Mutation SNP G A uc002veg.1 ERBB4_uc002veh.... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 NCIH1869_LUNG 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FLCN 17 17129486 17129486 NCIH1869_LUNG 37 Intron SNP T C uc002gra.3 PLD6_uc010cpn.2... Hybrid_Cap... view
FOXO1 p.P538L 13 41134015 41134015 NCIH1869_LUNG 37 Missense_Mutation SNP G A uc001uxl.3 FOXO1_uc010acc.... Hybrid_Cap... view
GPR112 p.D2657del X 135474445 135474447 NCIH1869_LUNG 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 NCIH1869_LUNG 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 NCIH1869_LUNG 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HSP90B1 p.E791del 12 104341188 104341190 NCIH1869_LUNG 37 In_Frame_Del Del GAA - rs117491163 uc001tkb.1 HSP90B1_uc010sw... Hybrid_Cap...
ILK 11 6630029 6630029 NCIH1869_LUNG 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITGAV p.S924N 2 187540395 187540395 NCIH1869_LUNG 37 Missense_Mutation SNP G A rs56316527 uc002upq.2 ITGAV_uc010frs.... Hybrid_Cap... view
ITPR2 p.R470_splice 12 26834804 26834805 NCIH1869_LUNG 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
LETM2 8 38265796 38265798 NCIH1869_LUNG 37 3'UTR Del ACT - uc003xlm.1 LETM2_uc003xll.... Hybrid_Cap...
LRP1 p.P224L 12 57539103 57539103 NCIH1869_LUNG 37 Missense_Mutation SNP C T uc001snd.2 LRP1_uc010sre.1... Hybrid_Cap... view
MAML2 p.604_607QQQQ>Q 11 95825375 95825383 NCIH1869_LUNG 37 In_Frame_Del Del TGCTG... - rs113349418 uc001pfw.1 Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 NCIH1869_LUNG 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 NCIH1869_LUNG 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 NCIH1869_LUNG 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MET p.Y989C 7 116411927 116411927 NCIH1869_LUNG 37 Missense_Mutation SNP A G uc010lkh.2 MET_uc003vij.2_... Hybrid_Cap... view
MLL3 p.A117V 7 152027725 152027725 NCIH1869_LUNG 37 Missense_Mutation SNP G A uc003wla.2 Hybrid_Cap... view
MLLT10 p.K203N 10 21906046 21906046 NCIH1869_LUNG 37 Missense_Mutation SNP G C uc001iqs.2 MLLT10_uc001iqt... Hybrid_Cap... view
MLLT3 9 20346377 20346378 NCIH1869_LUNG 37 3'UTR Ins - A rs66943046 uc003zoe.2 MLLT3_uc011lne.... Hybrid_Cap...
MMP1 p.I191fs 11 102667447 102667447 NCIH1869_LUNG 37 Frame_Shift_Del Del A - uc001phi.2 MMP1_uc010ruv.1... Hybrid_Cap...
NCAM1 11 112832307 112832308 NCIH1869_LUNG 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 NCIH1869_LUNG 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NFIA 1 61921185 61921186 NCIH1869_LUNG 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NIPBL 5 37065069 37065070 NCIH1869_LUNG 37 3'UTR Ins - A rs71759480 uc003jkl.3 NIPBL_uc003jkk.... Hybrid_Cap...
NLRP3 p.L609M 1 247588570 247588570 NCIH1869_LUNG 37 Missense_Mutation SNP C A uc001icr.2 NLRP3_uc001ics.... Hybrid_Cap... view
NPR1 1 153665919 153665920 NCIH1869_LUNG 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 NCIH1869_LUNG 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NTRK3 p.V799L 15 88420291 88420291 NCIH1869_LUNG 37 Missense_Mutation SNP C G uc002bme.1 NTRK3_uc002bmh.... Hybrid_Cap... view
PDE4DIP p.Q1665fs 1 144873963 144873963 NCIH1869_LUNG 37 Frame_Shift_Del Del T - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDE4DIP p.V486fs 1 144917828 144917828 NCIH1869_LUNG 37 Frame_Shift_Del Del A - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDGFRA 4 55131002 55131002 NCIH1869_LUNG 37 Intron Del A - uc003han.3 PDGFRA_uc003haa... Hybrid_Cap...
PIK3C2G p.P129del 12 18435399 18435401 NCIH1869_LUNG 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PIK3R4 p.E529_splice 3 130447530 130447531 NCIH1869_LUNG 37 Splice_Site_Ins Ins - A rs5852606 uc003enj.2 Hybrid_Cap...
PPARG 3 12447693 12447693 NCIH1869_LUNG 37 Intron SNP A T uc003bwx.2 PPARG_uc003bwr.... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 NCIH1869_LUNG 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PTPRC p.S73C 1 198665964 198665964 NCIH1869_LUNG 37 Missense_Mutation SNP C G uc001gur.1 PTPRC_uc001gus.... Hybrid_Cap... view
SLC14A1 p.A325E 18 43319270 43319270 NCIH1869_LUNG 37 Missense_Mutation SNP C A uc010dnk.2 SLC14A1_uc010xc... Hybrid_Cap... view
SMURF1 p.H263Y 7 98648999 98648999 NCIH1869_LUNG 37 Missense_Mutation SNP G A uc003upu.1 SMURF1_uc003upv... Hybrid_Cap... view
SOX11 p.P128L 2 5833236 5833236 NCIH1869_LUNG 37 Missense_Mutation SNP C T uc002qyj.2 Hybrid_Cap... view
STAT5B p.F416V 17 40369406 40369406 NCIH1869_LUNG 37 Missense_Mutation SNP A C uc002hzh.2 Hybrid_Cap... view
TIAM1 p.A1350S 21 32499468 32499468 NCIH1869_LUNG 37 Missense_Mutation SNP C A uc002yow.1 TIAM1_uc011adk.... Hybrid_Cap... view
TLR4 p.I226L 9 120475082 120475082 NCIH1869_LUNG 37 Missense_Mutation SNP A C uc004bjz.2 TLR4_uc004bka.2... Hybrid_Cap... view
TP53 p.M237I 17 7577570 7577570 NCIH1869_LUNG 37 Missense_Mutation SNP C T uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TRPS1 8 116635872 116635873 NCIH1869_LUNG 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TTN 2 179612144 179612144 NCIH1869_LUNG 37 Intron SNP C G uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 NCIH1869_LUNG 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...