Annotation Summary for Cell Line: NCI-H1915  

Cell line primary name: NCI-H1915
Cell line aliases: H1915
Gender: F
Site Primary: lung
Histology: carcinoma
Hist Subtype1: large_cell_carcinoma
Notes:
Source: ATCC
Expression arrays: BITTS_p_NCLE_RNA12_HG-U133_Plus_2_E04_698784
SNP arrays: SKATS_p_NCLE_DNAAffy13_GenomeWideSNP_6_B02_592946
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in NCI-H1915

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 NCIH1915_LUNG 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ABL1 p.R351W 9 133748333 133748333 NCIH1915_LUNG 37 Missense_Mutation SNP C T uc004bzv.2 ABL1_uc004bzw.2... Hybrid_Cap... view
ABL2 1 179086419 179086420 NCIH1915_LUNG 37 Intron Ins - A rs72207641 uc001gmj.3 ABL2_uc010pnf.1... Hybrid_Cap...
ACACA 17 35766564 35766564 NCIH1915_LUNG 37 5'UTR Del A - uc002hno.2 ACACA_uc002hnn.... Hybrid_Cap...
ACVR2B p.R482W 3 38524728 38524728 NCIH1915_LUNG 37 Missense_Mutation SNP C T uc003cif.2 ACVR2B_uc003cig... Hybrid_Cap... view
ADAM17 2 9630245 9630245 NCIH1915_LUNG 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM18 8 39468365 39468365 NCIH1915_LUNG 37 Intron SNP G T uc003xni.2 ADAM18_uc003xnh... Hybrid_Cap... view
ADAM28 8 24211994 24211997 NCIH1915_LUNG 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADAMTS20 p.G983V 12 43826255 43826255 NCIH1915_LUNG 37 Missense_Mutation SNP C A uc010skx.1 ADAMTS20_uc001r... Hybrid_Cap... view
AKAP9 p.1335_1336insQ 7 91652178 91652179 NCIH1915_LUNG 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
AKAP9 7 91670318 91670319 NCIH1915_LUNG 37 Intron Ins - T rs66490357 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 NCIH1915_LUNG 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ASPH p.A264_splice 8 62550924 62550925 NCIH1915_LUNG 37 Splice_Site_Ins Ins - A rs5891816 uc003xuj.2 ASPH_uc011leg.1... Hybrid_Cap...
ASPH 8 62602295 62602296 NCIH1915_LUNG 37 Intron Ins - A rs78500357 uc003xuj.2 ASPH_uc011leg.1... Hybrid_Cap...
BAI1 p.P629S 8 143562671 143562671 NCIH1915_LUNG 37 Missense_Mutation SNP C T uc003ywm.2 Hybrid_Cap... view
BCL11B p.A233S 14 99642476 99642476 NCIH1915_LUNG 37 Missense_Mutation SNP C A uc001yga.2 BCL11B_uc001ygb... Hybrid_Cap... view
BCR 22 23631813 23631814 NCIH1915_LUNG 37 Intron Ins - C rs66503844 uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BCR 22 23632777 23632778 NCIH1915_LUNG 37 Intron Ins - T uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
CABC1 1 227171585 227171585 NCIH1915_LUNG 37 Intron Del T - uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CARD10 p.KE272del 22 37906309 37906314 NCIH1915_LUNG 37 In_Frame_Del Del CTCCT... - uc003asx.1 CARD10_uc003ast... Hybrid_Cap...
CASP9 p.R45R 1 15844888 15844888 NCIH1915_LUNG 37 Silent SNP C G uc001awn.2 CASP9_uc001awm.... Hybrid_Cap... view
CDK11B 1 1654066 1654068 NCIH1915_LUNG 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CDK5 7 150754954 150754954 NCIH1915_LUNG 37 5'UTR SNP C A uc003wir.1 CDK5_uc003wis.1... Hybrid_Cap... view
CIT 12 120125896 120125896 NCIH1915_LUNG 37 3'UTR SNP C T uc001txj.1 CIT_uc001txh.1_... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 NCIH1915_LUNG 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
DACH1 13 72014625 72014626 NCIH1915_LUNG 37 3'UTR Ins - T rs117109529 uc010thn.1 DACH1_uc010tho.... Hybrid_Cap...
DST p.R4159P 6 56374619 56374619 NCIH1915_LUNG 37 Missense_Mutation SNP C G uc003pdf.2 DST_uc003pcz.3_... Hybrid_Cap... view
EPHA3 p.W52_splice 3 89259009 89259009 NCIH1915_LUNG 37 Splice_Site_SNP SNP G T uc003dqy.2 EPHA3_uc003dqx.... Hybrid_Cap... view
ETV1 7 14028708 14028708 NCIH1915_LUNG 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FBN1 p.S352Y 15 48812948 48812948 NCIH1915_LUNG 37 Missense_Mutation SNP G T uc001zwx.1 Hybrid_Cap... view
FBN2 p.V994A 5 127685047 127685047 NCIH1915_LUNG 37 Missense_Mutation SNP A G uc003kuu.2 FBN2_uc003kuv.2... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 NCIH1915_LUNG 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FLI1 11 128638217 128638217 NCIH1915_LUNG 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FN1 2 216244182 216244185 NCIH1915_LUNG 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GLI3 p.S850I 7 42006122 42006122 NCIH1915_LUNG 37 Missense_Mutation SNP C A uc011kbh.1 GLI3_uc011kbg.1... Hybrid_Cap... view
GPR112 p.T283N X 135426713 135426713 NCIH1915_LUNG 37 Missense_Mutation SNP C A uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap... view
GPR112 p.D2657del X 135474445 135474447 NCIH1915_LUNG 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRB7 p.R60C 17 37898841 37898841 NCIH1915_LUNG 37 Missense_Mutation SNP C T rs61638836 uc002hsr.2 GRB7_uc002hss.2... Hybrid_Cap... view
GRIA3 X 122318386 122318387 NCIH1915_LUNG 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GRIN2B p.R1216L 12 13716525 13716525 NCIH1915_LUNG 37 Missense_Mutation SNP C A uc001rbt.2 Hybrid_Cap... view
GUCY2C 12 14827464 14827466 NCIH1915_LUNG 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HDAC4 p.K737Q 2 240024481 240024481 NCIH1915_LUNG 37 Missense_Mutation SNP T G uc002vyk.3 HDAC4_uc010fyz.... Hybrid_Cap... view
HGF p.K137N 7 81386576 81386576 NCIH1915_LUNG 37 Missense_Mutation SNP C A uc003uhl.2 HGF_uc003uhm.2_... Hybrid_Cap... view
HNF1A 12 121434630 121434631 NCIH1915_LUNG 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
HRAS p.Q61L 11 533874 533874 NCIH1915_LUNG 37 Missense_Mutation SNP T A uc001lpv.2 HRAS_uc010qvw.1... Hybrid_Cap... view
HSPA1B 6 31797769 31797770 NCIH1915_LUNG 37 3'UTR Ins - AAGTT rs67206812 uc003nxk.2 Hybrid_Cap...
ILK 11 6630029 6630029 NCIH1915_LUNG 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
JAK1 p.I62V 1 65348981 65348981 NCIH1915_LUNG 37 Missense_Mutation SNP T C uc001dbu.1 JAK1_uc009wam.1... Hybrid_Cap... view
KCNH2 p.D466Y 7 150649674 150649674 NCIH1915_LUNG 37 Missense_Mutation SNP C A uc003wic.2 KCNH2_uc003wib.... Hybrid_Cap... view
KLK7 19 51480672 51480675 NCIH1915_LUNG 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LRP1B p.D4517Y 2 140995732 140995732 NCIH1915_LUNG 37 Missense_Mutation SNP C A uc002tvj.1 Hybrid_Cap... view
LRRK2 p.R1639T 12 40713878 40713878 NCIH1915_LUNG 37 Missense_Mutation SNP G C uc001rmg.3 LRRK2_uc009zjw.... Hybrid_Cap... view
MAF 16 79628537 79628537 NCIH1915_LUNG 37 Intron Del T - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAML2 p.604_607QQQQ>Q 11 95825375 95825383 NCIH1915_LUNG 37 In_Frame_Del Del TGCTG... - rs113349418 uc001pfw.1 Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 NCIH1915_LUNG 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 NCIH1915_LUNG 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MLL3 p.A829D 7 151945033 151945033 NCIH1915_LUNG 37 Missense_Mutation SNP G T uc003wla.2 Hybrid_Cap... view
MYD88 p.S121C 3 38180513 38180513 NCIH1915_LUNG 37 Missense_Mutation SNP A T uc003chx.2 ACAA1_uc003cht.... Hybrid_Cap... view
NCAM1 11 112832307 112832308 NCIH1915_LUNG 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 NCIH1915_LUNG 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA3 p.Q1276del 20 46279837 46279839 NCIH1915_LUNG 37 In_Frame_Del Del CAG - rs2664555 uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NCOA3 20 46282339 46282340 NCIH1915_LUNG 37 3'UTR Ins - AT uc002xtk.2 NCOA3_uc002xtl.... Hybrid_Cap...
NCOA4 p.A227V 10 51582857 51582857 NCIH1915_LUNG 37 Missense_Mutation SNP C T uc009xon.2 PARG_uc001jih.2... Hybrid_Cap... view
NEK3 p.K313_splice 13 52718050 52718051 NCIH1915_LUNG 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NEK3 p.G8S 13 52730368 52730368 NCIH1915_LUNG 37 Missense_Mutation SNP C T uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap... view
NOTCH4 p.12_16LLLLL>L 6 32191659 32191670 NCIH1915_LUNG 37 In_Frame_Del Del AGCAG... - uc003obb.2 NOTCH4_uc011dpu... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 NCIH1915_LUNG 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
PAX3 2 223158653 223158653 NCIH1915_LUNG 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PDCD11 p.R1820Q 10 105205149 105205149 NCIH1915_LUNG 37 Missense_Mutation SNP G A uc001kwy.1 Hybrid_Cap... view
PGR 11 100933598 100933599 NCIH1915_LUNG 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PKN2 p.T402I 1 89251820 89251820 NCIH1915_LUNG 37 Missense_Mutation SNP C T uc001dmn.2 PKN2_uc001dmm.1... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 NCIH1915_LUNG 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PRKDC p.A199T 8 48866393 48866393 NCIH1915_LUNG 37 Missense_Mutation SNP C T uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap... view
PRKG1 10 52751088 52751089 NCIH1915_LUNG 37 5'UTR Ins - GCT rs67900156;rs71029335 uc001jjm.2 PRKG1_uc010qhp.... Hybrid_Cap...
RAGE 14 102695606 102695606 NCIH1915_LUNG 37 3'UTR SNP G C uc001ylm.2 RAGE_uc010txv.1... Hybrid_Cap... view
RARA p.P78L 17 38504622 38504622 NCIH1915_LUNG 37 Missense_Mutation SNP C T uc002huk.1 RARA_uc002hul.3... Hybrid_Cap... view
RECQL4 p.R766fs 8 145738768 145738768 NCIH1915_LUNG 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
ROBO1 p.W384L 3 78737817 78737817 NCIH1915_LUNG 37 Missense_Mutation SNP C A uc003dqe.2 ROBO1_uc003dqb.... Hybrid_Cap... view
RPS6KL1 14 75373626 75373627 NCIH1915_LUNG 37 3'UTR Ins - TGAT uc001xqx.1 RPS6KL1_uc001xq... Hybrid_Cap...
RUNX1T1 p.A436V 8 92998357 92998357 NCIH1915_LUNG 37 Missense_Mutation SNP G A uc011lgi.1 RUNX1T1_uc003yf... Hybrid_Cap... view
RUNX2 6 45515197 45515197 NCIH1915_LUNG 37 3'UTR SNP A G uc011dvx.1 RUNX2_uc011dvy.... Hybrid_Cap... view
SIRT1 10 69676547 69676548 NCIH1915_LUNG 37 3'UTR Ins - T rs61666042 uc001jnd.2 SIRT1_uc010qis.... Hybrid_Cap...
SKIL p.Q662R 3 170110135 170110135 NCIH1915_LUNG 37 Missense_Mutation SNP A G uc003fgu.2 SKIL_uc011bps.1... Hybrid_Cap... view
SMG1 p.A2602T 16 18847508 18847508 NCIH1915_LUNG 37 Missense_Mutation SNP C T uc002dfm.2 SMG1_uc010bwb.2... Hybrid_Cap... view
SPEN 1 16266066 16266066 NCIH1915_LUNG 37 3'UTR SNP G T uc001axk.1 SPEN_uc010obp.1... Hybrid_Cap... view
STAR 8 38008591 38008591 NCIH1915_LUNG 37 De_novo_Start_OutOfFrame SNP C A uc003xkv.1 STAR_uc010lwc.1... Hybrid_Cap... view
STAT1 2 191840353 191840353 NCIH1915_LUNG 37 Intron Del T - uc002usj.2 STAT1_uc010fse.... Hybrid_Cap...
STK31 7 23872024 23872025 NCIH1915_LUNG 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
STK36 2 219537477 219537477 NCIH1915_LUNG 37 5'UTR SNP T G uc002viu.2 STK36_uc002viv.... Hybrid_Cap... view
TEC 4 48139307 48139310 NCIH1915_LUNG 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TFG p.A217S 3 100455488 100455488 NCIH1915_LUNG 37 Missense_Mutation SNP G T uc003due.2 TFG_uc003duf.2_... Hybrid_Cap... view
TGFBR2 p.V412L 3 30713834 30713834 NCIH1915_LUNG 37 Missense_Mutation SNP G T rs35766612 uc003cen.2 TGFBR2_uc003ceo... Hybrid_Cap... view
TMEM123 11 102269398 102269398 NCIH1915_LUNG 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TNRC6B p.Q1328del 22 40697177 40697179 NCIH1915_LUNG 37 In_Frame_Del Del GCA - rs114291931 uc011aor.1 TNRC6B_uc003aym... Hybrid_Cap...
TP53 p.K291* 17 7577067 7577067 NCIH1915_LUNG 37 Nonsense_Mutation SNP T A uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TRPM8 p.K158N 2 234847767 234847767 NCIH1915_LUNG 37 Missense_Mutation SNP G T uc002vvh.2 TRPM8_uc010fyj.... Hybrid_Cap... view
TRPS1 p.D1252G 8 116426381 116426381 NCIH1915_LUNG 37 Missense_Mutation SNP T C uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap... view
TRPS1 8 116635872 116635873 NCIH1915_LUNG 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
UBR5 p.A511P 8 103338842 103338842 NCIH1915_LUNG 37 Missense_Mutation SNP C G uc003ykr.1 UBR5_uc003yks.1... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 NCIH1915_LUNG 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...