Annotation Summary for Cell Line: NCI-H1944  

Cell line primary name: NCI-H1944
Cell line aliases: H1944
Gender: F
Site Primary: lung
Histology: carcinoma
Hist Subtype1: non_small_cell_carcinoma
Notes:
Source: ATCC
Expression arrays: WATCH_p_NCLE_RNA8_HG-U133_Plus_2_B11_474698
SNP arrays: BOWER_p_NCLE_DNAAffy8_GenomeWideSNP_6_C10_464560
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in NCI-H1944

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ABCC4 p.P870S 13 95735472 95735472 NCIH1944_LUNG 37 Missense_Mutation SNP G A uc001vmd.3 ABCC4_uc010afk.... Hybrid_Cap... view
ADAM17 2 9630245 9630245 NCIH1944_LUNG 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 NCIH1944_LUNG 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADAMTS19 p.Q1205R 5 129072901 129072901 NCIH1944_LUNG 37 Missense_Mutation SNP A G uc003kvb.1 ADAMTS19_uc010j... Hybrid_Cap... view
AKAP12 p.1531_1532insE 6 151674116 151674117 NCIH1944_LUNG 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ASPH p.A264_splice 8 62550924 62550925 NCIH1944_LUNG 37 Splice_Site_Ins Ins - A rs5891816 uc003xuj.2 ASPH_uc011leg.1... Hybrid_Cap...
ATP11A 13 113536455 113536455 NCIH1944_LUNG 37 3'UTR SNP C T uc001vsj.3 ATP11A_uc001vsi... Hybrid_Cap... view
ATR p.A2366T 3 142180878 142180878 NCIH1944_LUNG 37 Missense_Mutation SNP C T uc003eux.3 ATR_uc003euy.1_... Hybrid_Cap... view
ATR p.R2363* 3 142180887 142180887 NCIH1944_LUNG 37 Nonsense_Mutation SNP G A uc003eux.3 ATR_uc003euy.1_... Hybrid_Cap... view
BRD2 6 32948599 32948599 NCIH1944_LUNG 37 3'UTR Del C - uc010juh.2 BRD2_uc003ocn.3... Hybrid_Cap...
C15ORF2 p.G731W 15 24923205 24923205 NCIH1944_LUNG 37 Missense_Mutation SNP G T uc001ywo.2 Hybrid_Cap... view
CDH2 p.A610S 18 25565639 25565639 NCIH1944_LUNG 37 Missense_Mutation SNP C A uc002kwg.2 CDH2_uc010xbn.1... Hybrid_Cap... view
CDK13 7 40102342 40102342 NCIH1944_LUNG 37 Intron SNP C T uc003thh.3 CDK13_uc003thi.... Hybrid_Cap... view
CDKL5 X 18671680 18671680 NCIH1944_LUNG 37 3'UTR SNP G T uc004cym.2 CDKL5_uc004cyn.... Hybrid_Cap... view
CEP110 p.P1299L 9 123912694 123912694 NCIH1944_LUNG 37 Missense_Mutation SNP C T uc004bkx.1 CEP110_uc004bky... Hybrid_Cap... view
CHD9 p.2164_2165SS>S 16 53338410 53338412 NCIH1944_LUNG 37 In_Frame_Del Del TTC - uc002ehb.2 CHD9_uc002egy.2... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 NCIH1944_LUNG 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN5 p.A871P 11 100170119 100170119 NCIH1944_LUNG 37 Missense_Mutation SNP G C uc001pga.2 CNTN5_uc001pfz.... Hybrid_Cap... view
COL3A1 p.P553T 2 189860899 189860899 NCIH1944_LUNG 37 Missense_Mutation SNP C A uc002uqj.1 Hybrid_Cap... view
CREB3L2 p.T100del 7 137612914 137612916 NCIH1944_LUNG 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CUBN p.T1171N 10 17087166 17087166 NCIH1944_LUNG 37 Missense_Mutation SNP G T uc001ioo.2 Hybrid_Cap... view
CXCL12 10 44873992 44873993 NCIH1944_LUNG 37 Intron Ins - CT rs117617571 uc001jbh.2 CXCL12_uc001jbf... Hybrid_Cap...
CYP3A4 p.A297D 7 99361614 99361614 NCIH1944_LUNG 37 Missense_Mutation SNP G T uc003urv.1 CYP3A4_uc003urw... Hybrid_Cap... view
DACH1 p.Q404K 13 72147061 72147061 NCIH1944_LUNG 37 Missense_Mutation SNP G T uc010thn.1 DACH1_uc010tho.... Hybrid_Cap... view
DAPK1 p.A25P 9 90219879 90219879 NCIH1944_LUNG 37 Missense_Mutation SNP G C uc004apc.2 DAPK1_uc004ape.... Hybrid_Cap... view
EEF1D p.RDRRGR326del 8 144671408 144671425 NCIH1944_LUNG 37 In_Frame_Del Del TGCGG... - uc003yyq.1 EEF1D_uc003yyp.... Hybrid_Cap...
EP300 22 41574970 41574972 NCIH1944_LUNG 37 3'UTR Del GTA - rs76489032 uc003azl.3 Hybrid_Cap...
EPHA5 4 66189753 66189754 NCIH1944_LUNG 37 3'UTR Ins - T rs67487372 uc011cah.1 EPHA5_uc003hcx.... Hybrid_Cap...
EPHA5 p.A852S 4 66213879 66213879 NCIH1944_LUNG 37 Missense_Mutation SNP C A uc011cah.1 EPHA5_uc003hcx.... Hybrid_Cap... view
EPHA6 3 97367230 97367231 NCIH1944_LUNG 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
FAM123B p.G369R X 63412062 63412062 NCIH1944_LUNG 37 Missense_Mutation SNP C T uc004dvo.2 Hybrid_Cap... view
FANCD2 3 10143086 10143087 NCIH1944_LUNG 37 3'UTR Ins - A uc003bux.1 FANCD2_uc003buy... Hybrid_Cap...
FBXW7 p.V200I 4 153268210 153268210 NCIH1944_LUNG 37 Missense_Mutation SNP C T uc003ims.2 FBXW7_uc011cii.... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 NCIH1944_LUNG 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FLI1 11 128638217 128638217 NCIH1944_LUNG 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLI1 11 128638222 128638223 NCIH1944_LUNG 37 Intron Ins - T uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLNB p.A547V 3 58090836 58090836 NCIH1944_LUNG 37 Missense_Mutation SNP C T uc010hne.2 FLNB_uc003djj.2... Hybrid_Cap... view
FLT1 13 28896715 28896715 NCIH1944_LUNG 37 Intron SNP G T uc001usb.3 FLT1_uc010aap.2... Hybrid_Cap... view
FN1 2 216244182 216244185 NCIH1944_LUNG 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
FZD1 p.93_94insP 7 90894459 90894460 NCIH1944_LUNG 37 In_Frame_Ins Ins - CCG uc003ula.2 Hybrid_Cap...
GATA1 p.G255R X 48651597 48651597 NCIH1944_LUNG 37 Missense_Mutation SNP G C uc004dkq.3 Hybrid_Cap... view
GOLGA5 p.D402N 14 93277983 93277983 NCIH1944_LUNG 37 Missense_Mutation SNP G A uc001yaz.1 Hybrid_Cap... view
GRIA3 X 122318386 122318387 NCIH1944_LUNG 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GRIN2A p.G354C 16 9984905 9984905 NCIH1944_LUNG 37 Missense_Mutation SNP C A uc002czo.3 GRIN2A_uc010uym... Hybrid_Cap... view
GUCY2C 12 14827464 14827466 NCIH1944_LUNG 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HDAC2 p.K239T 6 114277240 114277240 NCIH1944_LUNG 37 Missense_Mutation SNP T G uc003pwd.1 HDAC2_uc003pwc.... Hybrid_Cap... view
HSP90B1 12 104341645 104341648 NCIH1944_LUNG 37 3'UTR Del ACTG - rs2307842 uc001tkb.1 HSP90B1_uc010sw... Hybrid_Cap...
IKZF3 p.R396C 17 37922387 37922387 NCIH1944_LUNG 37 Missense_Mutation SNP G A uc002hsu.2 IKZF3_uc002htd.... Hybrid_Cap... view
ILK 11 6630029 6630029 NCIH1944_LUNG 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
INHBA 7 41729121 41729122 NCIH1944_LUNG 37 3'UTR Ins - T uc003thq.2 INHBA_uc003thr.... Hybrid_Cap...
KLK7 19 51480672 51480675 NCIH1944_LUNG 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
KRAS p.G13D 12 25398281 25398281 NCIH1944_LUNG 37 Missense_Mutation SNP C T rs112445441 uc001rgp.1 KRAS_uc001rgq.1... Hybrid_Cap... view
LAMA1 p.G170L 18 7050772 7050773 NCIH1944_LUNG 37 Missense_Mutation DNP CC AA uc002knm.2 LAMA1_uc010wzj.... Hybrid_Cap...
LETM2 8 38265796 38265798 NCIH1944_LUNG 37 3'UTR Del ACT - uc003xlm.1 LETM2_uc003xll.... Hybrid_Cap...
LRP1B p.D3138Y 2 141242925 141242925 NCIH1944_LUNG 37 Missense_Mutation SNP C A uc002tvj.1 Hybrid_Cap... view
LRP1B p.R3109I 2 141243011 141243011 NCIH1944_LUNG 37 Missense_Mutation SNP C A uc002tvj.1 Hybrid_Cap... view
LRRC7 p.D236E 1 70451960 70451960 NCIH1944_LUNG 37 Missense_Mutation SNP T A uc001dep.2 LRRC7_uc009wbg.... Hybrid_Cap... view
LRRC7 p.E671* 1 70502144 70502144 NCIH1944_LUNG 37 Nonsense_Mutation SNP G T uc001dep.2 LRRC7_uc009wbg.... Hybrid_Cap... view
MAF 16 79628325 79628325 NCIH1944_LUNG 37 3'UTR Del A - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 NCIH1944_LUNG 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP2K1 15 66679649 66679650 NCIH1944_LUNG 37 5'UTR Ins - C rs67229745 uc010bhq.2 Hybrid_Cap...
MAP2K3 p.S185P 17 21206531 21206531 NCIH1944_LUNG 37 Missense_Mutation SNP T C uc002gys.2 MAP2K3_uc002gyt... Hybrid_Cap... view
MAP3K1 p.N899I 5 56177723 56177723 NCIH1944_LUNG 37 Missense_Mutation SNP A T uc003jqw.3 Hybrid_Cap... view
MAP3K1 p.T949del 5 56177849 56177851 NCIH1944_LUNG 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 NCIH1944_LUNG 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAP3K14 p.R571S 17 43348533 43348533 NCIH1944_LUNG 37 Missense_Mutation SNP C G uc002iiw.1 MAP3K14_uc002ii... Hybrid_Cap... view
MAP3K5 p.988_989insD 6 136913666 136913667 NCIH1944_LUNG 37 In_Frame_Ins Ins - GTC uc003qhc.2 MAP3K5_uc011edj... Hybrid_Cap...
MAPK12 p.H231_splice 22 50694237 50694237 NCIH1944_LUNG 37 Splice_Site_SNP SNP A T uc003bkm.1 MAPK12_uc003bkn... Hybrid_Cap... view
MAPK4 p.R44W 18 48190458 48190458 NCIH1944_LUNG 37 Missense_Mutation SNP C T uc002lev.2 MAPK4_uc010xdm.... Hybrid_Cap... view
MLLT4 p.P742T 6 168315367 168315367 NCIH1944_LUNG 37 Missense_Mutation SNP C A uc003qwd.2 MLLT4_uc003qwb.... Hybrid_Cap... view
MTCP1 p.T28K X 154294203 154294203 NCIH1944_LUNG 37 Missense_Mutation SNP G T uc004fmz.2 MTCP1NB_uc004fm... Hybrid_Cap... view
NACA p.G816C 12 57112868 57112868 NCIH1944_LUNG 37 Missense_Mutation SNP C A uc009zoy.1 NACA_uc001slz.2... Hybrid_Cap... view
NAV3 p.W1346C 12 78516008 78516008 NCIH1944_LUNG 37 Missense_Mutation SNP G T uc001syp.2 NAV3_uc001syo.2... Hybrid_Cap... view
NBN p.K549E 8 90965672 90965672 NCIH1944_LUNG 37 Missense_Mutation SNP T C uc003yej.1 NBN_uc003yei.1_... Hybrid_Cap... view
NCAM1 11 112832307 112832308 NCIH1944_LUNG 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 NCIH1944_LUNG 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA1 p.S682L 2 24930384 24930384 NCIH1944_LUNG 37 Missense_Mutation SNP C T uc002rfk.2 NCOA1_uc010eye.... Hybrid_Cap... view
NCOA3 p.Q1276del 20 46279864 46279866 NCIH1944_LUNG 37 In_Frame_Del Del CAA - rs1132443;rs28529067 uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 NCIH1944_LUNG 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NFIA 1 61921185 61921186 NCIH1944_LUNG 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NFKB1 p.D917_splice 4 103534740 103534741 NCIH1944_LUNG 37 Splice_Site_Ins Ins - A rs35795162 uc011cep.1 NFKB1_uc011ceq.... Hybrid_Cap...
NIN p.H1872Q 14 51206038 51206038 NCIH1944_LUNG 37 Missense_Mutation SNP G T uc001wyi.2 NIN_uc001wyj.2_... Hybrid_Cap... view
NLRP3 p.S680Y 1 247588784 247588784 NCIH1944_LUNG 37 Missense_Mutation SNP C A uc001icr.2 NLRP3_uc001ics.... Hybrid_Cap... view
NPM1 5 170837734 170837734 NCIH1944_LUNG 37 3'UTR Del T - uc011dex.1 NPM1_uc003mbi.2... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 NCIH1944_LUNG 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 NCIH1944_LUNG 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
PAX3 2 223158653 223158653 NCIH1944_LUNG 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PER1 17 8054028 8054028 NCIH1944_LUNG 37 5'UTR SNP T C uc002gkd.2 PER1_uc010vuq.1... Hybrid_Cap... view
PIK3C2G p.P129del 12 18435399 18435401 NCIH1944_LUNG 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PKHD1 p.C2422G 6 51747977 51747977 NCIH1944_LUNG 37 Missense_Mutation SNP A C uc003pah.1 PKHD1_uc010jzn.... Hybrid_Cap... view
PKN2 p.L384del 1 89250482 89250484 NCIH1944_LUNG 37 In_Frame_Del Del TCT - uc001dmn.2 PKN2_uc001dmm.1... Hybrid_Cap...
PRKACB 1 84670439 84670440 NCIH1944_LUNG 37 Intron Ins - C rs67519258 uc001djl.2 PRKACB_uc001djj... Hybrid_Cap...
PRKAR1A p.V348I 17 66526486 66526486 NCIH1944_LUNG 37 Missense_Mutation SNP G A uc002jhg.2 PRKAR1A_uc002jh... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 NCIH1944_LUNG 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PTPN22 p.M265K 1 114394683 114394683 NCIH1944_LUNG 37 Missense_Mutation SNP A T uc001eds.2 PTPN22_uc009wgq... Hybrid_Cap... view
PTPRD p.Q774L 9 8499648 8499648 NCIH1944_LUNG 37 Missense_Mutation SNP T A uc003zkk.2 PTPRD_uc003zkp.... Hybrid_Cap... view
RARB p.T278K 3 25635019 25635020 NCIH1944_LUNG 37 Missense_Mutation DNP CC AA uc011awl.1 RARB_uc003cdi.1... Hybrid_Cap...
RASGRF2 p.S643I 5 80408518 80408518 NCIH1944_LUNG 37 Missense_Mutation SNP G T uc003kha.1 RASGRF2_uc011ct... Hybrid_Cap... view
RECQL4 p.R766fs 8 145738768 145738768 NCIH1944_LUNG 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
ROBO2 p.D1183V 3 77666906 77666906 NCIH1944_LUNG 37 Missense_Mutation SNP A T uc003dpz.2 ROBO2_uc003dpy.... Hybrid_Cap... view
RPS6KL1 14 75373626 75373627 NCIH1944_LUNG 37 3'UTR Ins - TGAT uc001xqx.1 RPS6KL1_uc001xq... Hybrid_Cap...
SERPINB4 p.L116S 18 61308998 61308998 NCIH1944_LUNG 37 Missense_Mutation SNP A G uc002ljf.2 SERPINB4_uc002l... Hybrid_Cap... view
SOCS3 p.G171fs 17 76354664 76354665 NCIH1944_LUNG 37 Frame_Shift_Ins Ins - C uc002jvl.2 Hybrid_Cap...
STK31 7 23872024 23872025 NCIH1944_LUNG 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
STK38L p.D418H 12 27475152 27475152 NCIH1944_LUNG 37 Missense_Mutation SNP G C uc001rhr.2 STK38L_uc001rhs... Hybrid_Cap... view
SUZ12 p.Y434C 17 30320891 30320891 NCIH1944_LUNG 37 Missense_Mutation SNP A G uc002hgs.2 SUZ12_uc002hgt.... Hybrid_Cap... view
TMEM123 11 102269398 102269398 NCIH1944_LUNG 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TNFAIP3 p.E693K 6 138201378 138201378 NCIH1944_LUNG 37 Missense_Mutation SNP G A uc003qhr.2 TNFAIP3_uc003qh... Hybrid_Cap... view
TNK2 p.L223L 3 195610157 195610157 NCIH1944_LUNG 37 Silent SNP C T uc003fvt.1 TNK2_uc003fvs.1... Hybrid_Cap... view
TNN p.G659V 1 175067588 175067588 NCIH1944_LUNG 37 Missense_Mutation SNP G T uc001gkl.1 TNN_uc010pmx.1_... Hybrid_Cap... view
TNRC6B p.Q1328del 22 40697177 40697179 NCIH1944_LUNG 37 In_Frame_Del Del GCA - rs114291931 uc011aor.1 TNRC6B_uc003aym... Hybrid_Cap...
TTN 2 179391639 179391640 NCIH1944_LUNG 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.S32604del 2 179395826 179395828 NCIH1944_LUNG 37 In_Frame_Del Del AGA - uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.P30325T 2 179404115 179404115 NCIH1944_LUNG 37 Missense_Mutation SNP G T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.R12759C 2 179485269 179485269 NCIH1944_LUNG 37 Missense_Mutation SNP G A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
ULK1 p.E73K 12 132380340 132380340 NCIH1944_LUNG 37 Missense_Mutation SNP G A uc001uje.2 Hybrid_Cap... view
USP6 p.S1347R 17 5074968 5074968 NCIH1944_LUNG 37 Missense_Mutation SNP C G uc002gau.1 USP6_uc002gav.1... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 NCIH1944_LUNG 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
WHSC1L1 p.S1384* 8 38133322 38133322 NCIH1944_LUNG 37 Nonsense_Mutation SNP G C uc003xli.2 WHSC1L1_uc011lb... Hybrid_Cap... view