Annotation Summary for Cell Line: NCI-H1963  

Cell line primary name: NCI-H1963
Cell line aliases: H-1963 | H1963
Gender: M
Site Primary: lung
Histology: carcinoma
Hist Subtype1: small_cell_carcinoma
Notes:
Source: ATCC
Expression arrays: BRAKE_p_NCLE_RNA2_HG-U133_Plus_2_D08_241128
SNP arrays: ARLES_p_NCLE_DNAAffy2_S_GenomeWideSNP_6_E05_256106
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in NCI-H1963

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 NCIH1963_LUNG 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ACACA 17 35766564 35766564 NCIH1963_LUNG 37 5'UTR Del A - uc002hno.2 ACACA_uc002hnn.... Hybrid_Cap...
ADAM28 8 24211994 24211997 NCIH1963_LUNG 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 NCIH1963_LUNG 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ALPK1 4 113347609 113347610 NCIH1963_LUNG 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
APBB1IP 10 26790074 26790074 NCIH1963_LUNG 37 Intron SNP C A uc001iss.2 APBB1IP_uc001is... Hybrid_Cap... view
ASPH p.G699C 8 62430118 62430118 NCIH1963_LUNG 37 Missense_Mutation SNP C A uc003xuj.2 ASPH_uc011leg.1... Hybrid_Cap... view
ASPH p.A264_splice 8 62550924 62550925 NCIH1963_LUNG 37 Splice_Site_Ins Ins - A rs5891816 uc003xuj.2 ASPH_uc011leg.1... Hybrid_Cap...
BAI3 p.V319L 6 69646497 69646497 NCIH1963_LUNG 37 Missense_Mutation SNP G T uc003pev.3 BAI3_uc010kak.2... Hybrid_Cap... view
BAI3 p.V344_splice 6 69653721 69653721 NCIH1963_LUNG 37 Splice_Site_SNP SNP G T uc003pev.3 BAI3_uc010kak.2... Hybrid_Cap... view
C17ORF37 17 37885640 37885641 NCIH1963_LUNG 37 3'UTR Ins - G rs75811535 uc002hsq.2 Hybrid_Cap...
CABC1 1 227171585 227171585 NCIH1963_LUNG 37 Intron Del T - uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CABC1 1 227171736 227171737 NCIH1963_LUNG 37 Intron Ins - T rs1574184 uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CD40 20 44746914 44746914 NCIH1963_LUNG 37 5'UTR Del T - uc002xrg.1 CD40_uc002xrf.1... Hybrid_Cap...
CHD9 p.N2661S 16 53358095 53358095 NCIH1963_LUNG 37 Missense_Mutation SNP A G uc002ehb.2 CHD9_uc002egy.2... Hybrid_Cap... view
CHEK2 p.S52P 22 29130556 29130556 NCIH1963_LUNG 37 Missense_Mutation SNP A G uc003adt.1 CHEK2_uc003ads.... Hybrid_Cap... view
CHRNA5 15 78885614 78885614 NCIH1963_LUNG 37 3'UTR SNP A G uc002bdy.2 CHRNA3_uc002bea... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 NCIH1963_LUNG 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CLTCL1 p.V521I 22 19220082 19220082 NCIH1963_LUNG 37 Missense_Mutation SNP C T uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap... view
CNTN6 3 1339681 1339686 NCIH1963_LUNG 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
CREB3L2 p.T100del 7 137612914 137612916 NCIH1963_LUNG 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CREBBP 16 3777691 3777691 NCIH1963_LUNG 37 3'UTR Del A - uc002cvv.2 CREBBP_uc002cvw... Hybrid_Cap...
CSMD3 8 113236990 113236990 NCIH1963_LUNG 37 3'UTR SNP G T uc003ynu.2 CSMD3_uc003yns.... Hybrid_Cap... view
CSMD3 p.L1676F 8 113516074 113516074 NCIH1963_LUNG 37 Missense_Mutation SNP C A uc003ynu.2 CSMD3_uc003yns.... Hybrid_Cap... view
CSNK1A1L p.S5C 13 37679381 37679381 NCIH1963_LUNG 37 Missense_Mutation SNP T A rs56224973 uc001uwm.1 Hybrid_Cap... view
CYP1A2 p.S89R 15 75042346 75042346 NCIH1963_LUNG 37 Missense_Mutation SNP C G uc002ayr.1 Hybrid_Cap... view
DBF4 p.S155T 7 87516656 87516656 NCIH1963_LUNG 37 Missense_Mutation SNP T A uc003ujf.1 DBF4_uc003ujh.1... Hybrid_Cap... view
DGKB p.I373V 7 14712571 14712571 NCIH1963_LUNG 37 Missense_Mutation SNP T C uc003ssz.2 DGKB_uc011jxt.1... Hybrid_Cap... view
DNMT3B p.R440fs 20 31384616 31384617 NCIH1963_LUNG 37 Frame_Shift_Ins Ins - G uc002wyc.2 DNMT3B_uc010ztx... Hybrid_Cap...
DST p.V3501M 6 56400003 56400003 NCIH1963_LUNG 37 Missense_Mutation SNP C T uc003pdf.2 DST_uc003pcz.3_... Hybrid_Cap... view
EDN1 6 12296150 12296151 NCIH1963_LUNG 37 Intron Ins - T rs66570617 uc003nae.3 EDN1_uc003nad.2... Hybrid_Cap...
EIF2AK3 p.Q667K 2 88876109 88876109 NCIH1963_LUNG 37 Missense_Mutation SNP G T uc002stc.3 Hybrid_Cap... view
EPHA6 p.547_548WA>*S 3 97124028 97124029 NCIH1963_LUNG 37 Nonsense_Mutation DNP GG AT uc010how.1 Hybrid_Cap...
EPHA6 3 97367230 97367231 NCIH1963_LUNG 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
EPHB6 7 142568771 142568771 NCIH1963_LUNG 37 3'UTR Del C - uc011kst.1 EPHB6_uc011ksu.... Hybrid_Cap...
ETV1 7 14028708 14028708 NCIH1963_LUNG 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FBN2 p.P2084fs 5 127627260 127627261 NCIH1963_LUNG 37 Frame_Shift_Ins Ins - T rs34845843 uc003kuu.2 Hybrid_Cap...
FGFR1OP 6 167453519 167453520 NCIH1963_LUNG 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FHIT p.G34L 3 60522595 60522596 NCIH1963_LUNG 37 Missense_Mutation DNP CC AA uc003dkx.3 FHIT_uc003dky.2... Hybrid_Cap...
FLI1 11 128638217 128638217 NCIH1963_LUNG 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FN1 2 216244182 216244185 NCIH1963_LUNG 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
FN1 p.P1552S 2 216249658 216249658 NCIH1963_LUNG 37 Missense_Mutation SNP G A uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap... view
FURIN p.I60_splice 15 91419484 91419484 NCIH1963_LUNG 37 Splice_Site_SNP SNP G T uc002bpu.1 Hybrid_Cap... view
GHR p.E563V 5 42719297 42719297 NCIH1963_LUNG 37 Missense_Mutation SNP A T uc003jmt.2 GHR_uc011cpq.1_... Hybrid_Cap... view
GMPS p.V296_splice 3 155632206 155632206 NCIH1963_LUNG 37 Splice_Site_SNP SNP A G uc003faq.2 GMPS_uc011bom.1... Hybrid_Cap... view
GPR112 p.D2657del X 135474445 135474447 NCIH1963_LUNG 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 NCIH1963_LUNG 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 NCIH1963_LUNG 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HIF1A 14 62213929 62213930 NCIH1963_LUNG 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HNF1A 12 121434630 121434631 NCIH1963_LUNG 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
ILK 11 6630029 6630029 NCIH1963_LUNG 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
KALRN p.Q2067* 3 124378290 124378290 NCIH1963_LUNG 37 Nonsense_Mutation SNP C T uc003ehg.2 KALRN_uc003ehi.... Hybrid_Cap... view
KLK7 19 51480672 51480675 NCIH1963_LUNG 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LRP1B p.A4537E 2 140992404 140992404 NCIH1963_LUNG 37 Missense_Mutation SNP G T uc002tvj.1 Hybrid_Cap... view
LRRC7 p.E21D 1 70225950 70225950 NCIH1963_LUNG 37 Missense_Mutation SNP A C uc001dep.2 LRRC7_uc001deo.... Hybrid_Cap... view
LRRC7 p.I1451K 1 70555423 70555423 NCIH1963_LUNG 37 Missense_Mutation SNP T A uc001dep.2 LRRC7_uc009wbg.... Hybrid_Cap... view
LRRK2 p.K1035N 12 40692053 40692053 NCIH1963_LUNG 37 Missense_Mutation SNP G T uc001rmg.3 LRRK2_uc001rmh.... Hybrid_Cap... view
LRRK2 12 40758914 40758914 NCIH1963_LUNG 37 Intron SNP T G uc001rmg.3 LRRK2_uc009zjw.... Hybrid_Cap... view
MAML2 p.604_607QQQQ>Q 11 95825375 95825383 NCIH1963_LUNG 37 In_Frame_Del Del TGCTG... - rs113349418 uc001pfw.1 Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 NCIH1963_LUNG 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 NCIH1963_LUNG 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 NCIH1963_LUNG 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MLL p.M604fs 11 118343686 118343689 NCIH1963_LUNG 37 Frame_Shift_Del Del GCAA - uc001ptb.2 MLL_uc001pta.2_... Hybrid_Cap...
MPPED2 11 30601967 30601967 NCIH1963_LUNG 37 5'UTR SNP A T uc001msr.2 MPPED2_uc001msq... Hybrid_Cap... view
MYH11 p.V1341L 16 15818620 15818620 NCIH1963_LUNG 37 Missense_Mutation SNP C A uc002ddx.2 MYH11_uc002ddv.... Hybrid_Cap... view
MYO18B p.D1920Y 22 26346342 26346342 NCIH1963_LUNG 37 Missense_Mutation SNP G T uc003abz.1 MYO18B_uc003aca... Hybrid_Cap... view
MYO3A p.T219M 10 26310502 26310502 NCIH1963_LUNG 37 Missense_Mutation SNP C T uc001isn.2 MYO3A_uc009xko.... Hybrid_Cap... view
MYO3A p.P874L 10 26436474 26436474 NCIH1963_LUNG 37 Missense_Mutation SNP C T uc001isn.2 MYO3A_uc009xko.... Hybrid_Cap... view
MYST4 p.E1104del 10 76781906 76781908 NCIH1963_LUNG 37 In_Frame_Del Del GAA - rs79644703 uc001jwn.1 MYST4_uc001jwm.... Hybrid_Cap...
NCAM1 11 112832307 112832308 NCIH1963_LUNG 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 NCIH1963_LUNG 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NLRP3 1 247611982 247611982 NCIH1963_LUNG 37 3'UTR Del C - uc001icr.2 NLRP3_uc001ics.... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 NCIH1963_LUNG 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NUP153 p.N436S 6 17661972 17661972 NCIH1963_LUNG 37 Missense_Mutation SNP T C uc011dje.1 NUP153_uc003ncd... Hybrid_Cap... view
PAX3 2 223158653 223158653 NCIH1963_LUNG 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PDK1 2 173460775 173460775 NCIH1963_LUNG 37 3'UTR SNP T C uc010zeb.1 PDK1_uc010zea.1... Hybrid_Cap... view
PGR 11 100933598 100933599 NCIH1963_LUNG 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PIK3C2G 12 18800990 18800990 NCIH1963_LUNG 37 3'UTR Del A - rs16914368 uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PIK3CG p.S806F 7 106519989 106519989 NCIH1963_LUNG 37 Missense_Mutation SNP C T uc003vdv.3 PIK3CG_uc003vdu... Hybrid_Cap... view
PIK3R1 5 67588875 67588875 NCIH1963_LUNG 37 Intron SNP A G uc003jva.2 PIK3R1_uc003jvb... Hybrid_Cap... view
PKHD1 p.Q2207L 6 51774143 51774143 NCIH1963_LUNG 37 Missense_Mutation SNP T A uc003pah.1 PKHD1_uc010jzn.... Hybrid_Cap... view
PKHD1 p.G1399C 6 51890413 51890413 NCIH1963_LUNG 37 Missense_Mutation SNP C A uc003pah.1 PKHD1_uc003pai.... Hybrid_Cap... view
PMS1 2 190670539 190670540 NCIH1963_LUNG 37 Intron Ins - A rs3214425 uc002urh.3 PMS1_uc010zga.1... Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 NCIH1963_LUNG 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
RAGE 14 102717957 102717957 NCIH1963_LUNG 37 Intron Del A - uc001ylm.2 RAGE_uc010txv.1... Hybrid_Cap...
RAP1GDS1 4 99313353 99313353 NCIH1963_LUNG 37 Intron Del T - uc003htw.3 RAP1GDS1_uc003h... Hybrid_Cap...
RAPGEF2 4 160189201 160189201 NCIH1963_LUNG 37 5'UTR Del T - uc003iqg.3 Hybrid_Cap...
RB1 p.C61* 13 48881461 48881461 NCIH1963_LUNG 37 Nonsense_Mutation SNP T A uc001vcb.2 RB1_uc010acs.1_... Hybrid_Cap... view
RECQL4 p.R766fs 8 145738768 145738768 NCIH1963_LUNG 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RIMS2 p.L219P 8 104898149 104898149 NCIH1963_LUNG 37 Missense_Mutation SNP T C uc003yls.2 RIMS2_uc003ylp.... Hybrid_Cap... view
RIMS2 p.T577I 8 104948799 104948799 NCIH1963_LUNG 37 Missense_Mutation SNP C T uc003yls.2 RIMS2_uc003ylp.... Hybrid_Cap... view
ROR2 p.E563G 9 94487088 94487088 NCIH1963_LUNG 37 Missense_Mutation SNP T C uc004arj.1 ROR2_uc004ari.1... Hybrid_Cap... view
ROR2 p.R94Q 9 94519736 94519736 NCIH1963_LUNG 37 Missense_Mutation SNP C T uc004arj.1 ROR2_uc004ari.1... Hybrid_Cap... view
ROS1 p.G764R 6 117706860 117706860 NCIH1963_LUNG 37 Missense_Mutation SNP C T uc003pxp.1 ROS1_uc011ebi.1... Hybrid_Cap... view
RPS6KA5 14 91360733 91360734 NCIH1963_LUNG 37 Intron Ins - T rs77438853 uc001xys.2 RPS6KA5_uc010tw... Hybrid_Cap...
SCYL1 p.R523Q 11 65303605 65303605 NCIH1963_LUNG 37 Missense_Mutation SNP G A uc001oea.1 SCYL1_uc009yqk.... Hybrid_Cap... view
SEPT9 17 75494787 75494788 NCIH1963_LUNG 37 3'UTR Ins - C rs5822173 uc002jts.3 SEPT9_uc010wtk.... Hybrid_Cap...
SLCO4A1 p.D202V 20 61288411 61288411 NCIH1963_LUNG 37 Missense_Mutation SNP A T uc002ydb.1 SLCO4A1_uc002yd... Hybrid_Cap... view
SLCO4A1 p.G496D 20 61299111 61299111 NCIH1963_LUNG 37 Missense_Mutation SNP G A uc002ydb.1 SLCO4A1_uc002yd... Hybrid_Cap... view
SMG1 p.R2456Q 16 18849382 18849382 NCIH1963_LUNG 37 Missense_Mutation SNP C T uc002dfm.2 SMG1_uc010bwb.2... Hybrid_Cap... view
SOX11 p.Y312H 2 5833787 5833787 NCIH1963_LUNG 37 Missense_Mutation SNP T C uc002qyj.2 Hybrid_Cap... view
STAG3 7 99786190 99786190 NCIH1963_LUNG 37 Intron Del T - uc003utx.1 STAG3_uc010lgs.... Hybrid_Cap...
STK31 7 23872024 23872025 NCIH1963_LUNG 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TCERG1L 10 132891219 132891219 NCIH1963_LUNG 37 3'UTR SNP T G uc001lkp.2 Hybrid_Cap... view
TFR2 p.A81T 7 100238644 100238644 NCIH1963_LUNG 37 Missense_Mutation SNP C T uc003uvv.1 TFR2_uc003uvw.1... Hybrid_Cap... view
TMEM123 11 102269398 102269398 NCIH1963_LUNG 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TP53 p.V147D 17 7578490 7578490 NCIH1963_LUNG 37 Missense_Mutation SNP A T uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TP53 p.H214R 17 7578208 7578208 NCIH1963_LUNG 37 Missense_Mutation SNP T C uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TRIM33 1 114940215 114940216 NCIH1963_LUNG 37 3'UTR Ins - G rs68133208 uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TRIM36 5 114462143 114462143 NCIH1963_LUNG 37 3'UTR SNP A C uc003kqs.2 TRIM36_uc011cwc... Hybrid_Cap... view
TRIM42 p.M219R 3 140401618 140401618 NCIH1963_LUNG 37 Missense_Mutation SNP T G uc003eto.1 Hybrid_Cap... view
TTN 2 179391639 179391640 NCIH1963_LUNG 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.F16314L 2 179463876 179463876 NCIH1963_LUNG 37 Missense_Mutation SNP A G uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.D5583V 2 179590569 179590569 NCIH1963_LUNG 37 Missense_Mutation SNP T A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 NCIH1963_LUNG 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
WDHD1 14 55408116 55408117 NCIH1963_LUNG 37 3'UTR Del AT - uc001xbm.1 WDHD1_uc010aom.... Hybrid_Cap...
ZFYVE9 p.R711M 1 52705221 52705221 NCIH1963_LUNG 37 Missense_Mutation SNP G T uc001cto.2 ZFYVE9_uc001ctn... Hybrid_Cap... view