Annotation Summary for Cell Line: NCI-H196  

Cell line primary name: NCI-H196
Cell line aliases: H196
Gender: M
Site Primary: lung
Histology: carcinoma
Hist Subtype1: small_cell_carcinoma
Notes:
Source: ATCC
Expression arrays: METIS_p_NCLE_RNA1_Human_U133_Plus_2.0_C03_240902
SNP arrays: ARLES_p_NCLE_DNAAffy2_S_GenomeWideSNP_6_C01_256050
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in NCI-H196

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ACACA 17 35766564 35766564 NCIH196_LUNG 37 5'UTR Del A - uc002hno.2 ACACA_uc002hnn.... Hybrid_Cap...
ADAM17 2 9630245 9630245 NCIH196_LUNG 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 NCIH196_LUNG 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADCK1 14 78390632 78390637 NCIH196_LUNG 37 Intron Del AAACT... - rs78274857;rs74969652 uc001xui.2 ADCK1_uc010tvo.... Hybrid_Cap...
AIM1 p.G207fs 6 106960835 106960835 NCIH196_LUNG 37 Frame_Shift_Del Del G - uc003prh.2 Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 NCIH196_LUNG 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 NCIH196_LUNG 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ALS2 p.G260V 2 202625938 202625938 NCIH196_LUNG 37 Missense_Mutation SNP C A uc002uyo.2 ALS2_uc002uyp.3... Hybrid_Cap... view
ANAPC5 p.Y9S 12 121790118 121790118 NCIH196_LUNG 37 Missense_Mutation SNP T G uc001uag.2 ANAPC5_uc001uah... Hybrid_Cap... view
BCL2 18 60795823 60795823 NCIH196_LUNG 37 3'UTR SNP C A uc002lit.1 BCL2_uc002liu.1... Hybrid_Cap... view
CABC1 1 227171585 227171585 NCIH196_LUNG 37 Intron Del T - uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CACNB2 10 18828721 18828722 NCIH196_LUNG 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CCDC6 p.E294D 10 61566802 61566802 NCIH196_LUNG 37 Missense_Mutation SNP T A uc001jks.3 Hybrid_Cap... view
CDK18 1 205495890 205495891 NCIH196_LUNG 37 Intron Del CT - uc001hcr.2 CDK18_uc010pri.... Hybrid_Cap...
CHD1 p.P1684del 5 98192165 98192167 NCIH196_LUNG 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CHD8 p.I839V 14 21871778 21871778 NCIH196_LUNG 37 Missense_Mutation SNP T C uc001was.1 CHD8_uc001war.1... Hybrid_Cap... view
CHEK2 p.S5S 22 29130695 29130695 NCIH196_LUNG 37 Silent SNP C T uc003adt.1 CHEK2_uc003ads.... Hybrid_Cap... view
CHIC2 4 54876132 54876132 NCIH196_LUNG 37 3'UTR Del C - rs4437313 uc003haj.1 PDGFRA_uc003haa... Hybrid_Cap...
COL3A1 p.G420C 2 189859023 189859023 NCIH196_LUNG 37 Missense_Mutation SNP G T uc002uqj.1 COL3A1_uc010frw... Hybrid_Cap... view
CSMD3 p.G1597C 8 113519026 113519026 NCIH196_LUNG 37 Missense_Mutation SNP C A uc003ynu.2 CSMD3_uc003yns.... Hybrid_Cap... view
CSNK1G1 p.I77V 15 64543774 64543774 NCIH196_LUNG 37 Missense_Mutation SNP T C uc002anh.1 CSNK1G1_uc002an... Hybrid_Cap... view
CXCL12 10 44873992 44873993 NCIH196_LUNG 37 Intron Ins - CT rs117617571 uc001jbh.2 CXCL12_uc001jbf... Hybrid_Cap...
DNMT1 p.K1431_splice 19 10248506 10248506 NCIH196_LUNG 37 Splice_Site_SNP SNP A C uc010xlc.1 DNMT1_uc002mne.... Hybrid_Cap... view
DYRK1A 21 38884966 38884967 NCIH196_LUNG 37 3'UTR Ins - T rs72430212 uc002ywk.2 DYRK1A_uc002ywi... Hybrid_Cap...
EP300 22 41574970 41574972 NCIH196_LUNG 37 3'UTR Del GTA - rs76489032 uc003azl.3 Hybrid_Cap...
EPHA6 3 97367230 97367231 NCIH196_LUNG 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
EPHA6 3 97467610 97467611 NCIH196_LUNG 37 3'UTR Ins - CT uc010how.1 Hybrid_Cap...
ETV1 7 14028708 14028708 NCIH196_LUNG 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
EWSR1 22 29687622 29687622 NCIH196_LUNG 37 Intron SNP A T uc003aev.2 EWSR1_uc003aet.... Hybrid_Cap... view
FFAR2 p.L264P 19 35941407 35941407 NCIH196_LUNG 37 Missense_Mutation SNP T C uc002nzg.2 FFAR2_uc010eea.... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 NCIH196_LUNG 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 NCIH196_LUNG 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLI1 11 128638217 128638217 NCIH196_LUNG 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
GLI1 p.E972Q 12 57865437 57865437 NCIH196_LUNG 37 Missense_Mutation SNP G C uc001snx.2 GLI1_uc009zpq.2... Hybrid_Cap... view
GPR112 p.D2657del X 135474445 135474447 NCIH196_LUNG 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 NCIH196_LUNG 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GRK1 p.I67V 13 114321900 114321900 NCIH196_LUNG 37 Missense_Mutation SNP A G uc010tkf.1 Hybrid_Cap... view
GUCY2C 12 14827464 14827466 NCIH196_LUNG 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HGF p.D117N 7 81388026 81388026 NCIH196_LUNG 37 Missense_Mutation SNP C T uc003uhl.2 HGF_uc003uhm.2_... Hybrid_Cap... view
HNF1A 12 121434630 121434631 NCIH196_LUNG 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
HSP90B1 12 104341645 104341648 NCIH196_LUNG 37 3'UTR Del ACTG - rs2307842 uc001tkb.1 HSP90B1_uc010sw... Hybrid_Cap...
ILK 11 6630029 6630029 NCIH196_LUNG 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
JAK2 p.W157* 9 5050687 5050687 NCIH196_LUNG 37 Nonsense_Mutation SNP G A uc010mhm.2 JAK2_uc003ziw.2... Hybrid_Cap... view
KCNH2 p.R894G 7 150645544 150645544 NCIH196_LUNG 37 Missense_Mutation SNP G C uc003wic.2 KCNH2_uc003wib.... Hybrid_Cap... view
KLK7 19 51480672 51480675 NCIH196_LUNG 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LAMP1 p.T64I 13 113963965 113963965 NCIH196_LUNG 37 Missense_Mutation SNP C T uc001vtm.1 LAMP1_uc010tka.... Hybrid_Cap... view
LETM2 8 38265796 38265798 NCIH196_LUNG 37 3'UTR Del ACT - uc003xlm.1 LETM2_uc003xll.... Hybrid_Cap...
LRP1B p.K901M 2 141747169 141747169 NCIH196_LUNG 37 Missense_Mutation SNP T A uc002tvj.1 LRP1B_uc010fnl.... Hybrid_Cap... view
LRP2 p.R4042C 2 170012811 170012811 NCIH196_LUNG 37 Missense_Mutation SNP G A uc002ues.2 Hybrid_Cap... view
LRRK2 p.S473_splice 12 40653281 40653281 NCIH196_LUNG 37 Splice_Site_SNP SNP G A uc001rmg.3 LRRK2_uc001rmh.... Hybrid_Cap... view
MAK p.R439Q 6 10791908 10791908 NCIH196_LUNG 37 Missense_Mutation SNP C T uc003mzl.2 SYCP2L_uc011dim... Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 NCIH196_LUNG 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 NCIH196_LUNG 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP4K3 p.F333_splice 2 39536662 39536662 NCIH196_LUNG 37 Splice_Site_SNP SNP T A uc002rro.2 MAP4K3_uc002rrp... Hybrid_Cap... view
MAP4K4 2 102507933 102507933 NCIH196_LUNG 37 3'UTR SNP A G uc002tbc.2 MAP4K4_uc002tbd... Hybrid_Cap... view
MAPKAPK3 3 50685575 50685575 NCIH196_LUNG 37 3'UTR Del A - rs76026164 uc003day.1 MAPKAPK3_uc003d... Hybrid_Cap...
MCF2 p.H349P X 138699805 138699805 NCIH196_LUNG 37 Missense_Mutation SNP T G uc011mwo.1 MCF2_uc004fau.2... Hybrid_Cap... view
MLL3 p.Y816fs 7 151945071 151945072 NCIH196_LUNG 37 Frame_Shift_Ins Ins - T uc003wla.2 Hybrid_Cap...
MLLT4 6 168370640 168370640 NCIH196_LUNG 37 3'UTR SNP A C uc003qwd.2 Hybrid_Cap... view
MTUS2 p.Q900H 13 29855866 29855866 NCIH196_LUNG 37 Missense_Mutation SNP G T uc001usl.3 Hybrid_Cap... view
MYH1 p.G1289_splice 17 10402411 10402411 NCIH196_LUNG 37 Splice_Site_SNP SNP T A uc002gmo.2 Hybrid_Cap... view
MYLK 3 123332923 123332923 NCIH196_LUNG 37 3'UTR Del C - uc003ego.2 MYLK_uc003egl.2... Hybrid_Cap...
NACA p.P1328L 12 57111331 57111331 NCIH196_LUNG 37 Missense_Mutation SNP G A uc009zoy.1 NACA_uc001slz.2... Hybrid_Cap... view
NCAM1 11 112832307 112832308 NCIH196_LUNG 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 NCIH196_LUNG 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NOTCH4 p.15_16LL>L 6 32191659 32191661 NCIH196_LUNG 37 In_Frame_Del Del AGC - uc003obb.2 NOTCH4_uc011dpu... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 NCIH196_LUNG 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NUP98 p.P1171R 11 3723693 3723693 NCIH196_LUNG 37 Missense_Mutation SNP G C uc001lyh.2 NUP98_uc001lyi.... Hybrid_Cap... view
NUP98 p.V1077M 11 3723976 3723976 NCIH196_LUNG 37 Missense_Mutation SNP C T uc001lyh.2 NUP98_uc001lyi.... Hybrid_Cap... view
PAK2 p.S508I 3 196555224 196555224 NCIH196_LUNG 37 Missense_Mutation SNP G T uc003fwy.3 Hybrid_Cap... view
PAX3 p.L307M 2 223085980 223085980 NCIH196_LUNG 37 Missense_Mutation SNP G T uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap... view
PAX3 2 223158653 223158653 NCIH196_LUNG 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PDE4DIP p.E243fs 1 144923729 144923729 NCIH196_LUNG 37 Frame_Shift_Del Del T - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDGFB 22 39636899 39636900 NCIH196_LUNG 37 Intron Ins - TCTC rs72014707 uc003axf.2 PDGFB_uc003axe.... Hybrid_Cap...
PDGFRA 4 55131002 55131002 NCIH196_LUNG 37 Intron Del A - uc003han.3 PDGFRA_uc003haa... Hybrid_Cap...
PEX5L 3 179754435 179754435 NCIH196_LUNG 37 5'UTR SNP C T uc003fki.1 PEX5L_uc003fkj.... Hybrid_Cap... view
PPARG p.I81F 3 12421361 12421361 NCIH196_LUNG 37 Missense_Mutation SNP A T uc003bwx.2 PPARG_uc003bwr.... Hybrid_Cap... view
PRKCD p.R273W 3 53218919 53218919 NCIH196_LUNG 37 Missense_Mutation SNP C T uc003dgl.2 PRKCD_uc003dgm.... Hybrid_Cap... view
PRKD1 p.32_33insSG 14 30396622 30396623 NCIH196_LUNG 37 In_Frame_Ins Ins - CCCGGA rs45441697 uc001wqh.2 Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 NCIH196_LUNG 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PRKG1 10 54053721 54053721 NCIH196_LUNG 37 3'UTR SNP A T uc001jjo.2 PRKG1_uc001jjm.... Hybrid_Cap... view
PTEN p.Y138C 10 89692929 89692929 NCIH196_LUNG 37 Missense_Mutation SNP A G uc001kfb.2 Hybrid_Cap... view
RAPGEF2 p.S1223C 4 160274698 160274698 NCIH196_LUNG 37 Missense_Mutation SNP C G uc003iqg.3 Hybrid_Cap... view
RASGRF1 15 79277150 79277151 NCIH196_LUNG 37 Intron Ins - C rs67045840;rs77640668 uc002beq.2 RASGRF1_uc002be... Hybrid_Cap...
RB1 p.Q383* 13 48947560 48947560 NCIH196_LUNG 37 Nonsense_Mutation SNP C T uc001vcb.2 RB1_uc010act.1_... Hybrid_Cap... view
RECQL4 p.R766fs 8 145738768 145738768 NCIH196_LUNG 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RICTOR p.V120V 5 39002669 39002669 NCIH196_LUNG 37 Silent SNP C T uc003jlo.2 RICTOR_uc003jlp... Hybrid_Cap... view
ROR1 1 64644595 64644595 NCIH196_LUNG 37 3'UTR SNP A G uc001dbj.2 Hybrid_Cap... view
SETDB1 p.S427I 1 150921610 150921610 NCIH196_LUNG 37 Missense_Mutation SNP G T uc001evu.2 SETDB1_uc009wmf... Hybrid_Cap... view
SORL1 11 121500401 121500401 NCIH196_LUNG 37 3'UTR Del A - uc001pxx.2 SORL1_uc010rzp.... Hybrid_Cap...
STAG3 p.V741_splice 7 99799408 99799408 NCIH196_LUNG 37 Splice_Site_SNP SNP G T uc003utx.1 STAG3_uc010lgs.... Hybrid_Cap... view
STAT1 2 191840353 191840353 NCIH196_LUNG 37 Intron Del T - uc002usj.2 STAT1_uc010fse.... Hybrid_Cap...
STAT1 p.G523A 2 191847123 191847123 NCIH196_LUNG 37 Missense_Mutation SNP C G uc002usj.2 STAT1_uc010fse.... Hybrid_Cap... view
STAT5A p.G431A 17 40456582 40456582 NCIH196_LUNG 37 Missense_Mutation SNP G C uc002hzj.1 STAT5A_uc010cya... Hybrid_Cap... view
STK17A 7 43664599 43664599 NCIH196_LUNG 37 3'UTR SNP C T uc003tih.2 C7orf44_uc003ti... Hybrid_Cap... view
STK31 7 23872024 23872025 NCIH196_LUNG 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
SUFU p.A22fs 10 104263973 104263974 NCIH196_LUNG 37 Frame_Shift_Ins Ins - C uc001kvy.1 SUFU_uc001kvw.1... Hybrid_Cap...
TACC3 4 1746789 1746789 NCIH196_LUNG 37 3'UTR SNP T C uc003gdo.2 TACC3_uc003gdp.... Hybrid_Cap... view
TAOK1 p.S60C 17 27794209 27794209 NCIH196_LUNG 37 Missense_Mutation SNP C G uc002hdz.1 TAOK1_uc010wbe.... Hybrid_Cap... view
TEC 4 48139307 48139310 NCIH196_LUNG 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TP53 17 7578078 7578079 NCIH196_LUNG 37 Intron DNP AA CC uc002gim.2 TP53_uc002gig.1... Hybrid_Cap...
TP53 p.R175H 17 7578406 7578406 NCIH196_LUNG 37 Missense_Mutation SNP C T rs28934578 uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TPO p.Q113R 2 1437368 1437368 NCIH196_LUNG 37 Missense_Mutation SNP A G uc002qww.2 TPO_uc010ewj.2_... Hybrid_Cap... view
TTBK1 p.E771del 6 43250726 43250728 NCIH196_LUNG 37 In_Frame_Del Del GAA - uc003ouq.1 Hybrid_Cap...
TTN 2 179391639 179391640 NCIH196_LUNG 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.L14934F 2 179473104 179473104 NCIH196_LUNG 37 Missense_Mutation SNP C A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.A8208S 2 179575470 179575470 NCIH196_LUNG 37 Missense_Mutation SNP C A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 NCIH196_LUNG 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
WHSC1 4 1941667 1941667 NCIH196_LUNG 37 Intron SNP G A uc003gdz.3 WHSC1_uc003geb.... Hybrid_Cap... view
WHSC1L1 p.E1183K 8 38139056 38139056 NCIH196_LUNG 37 Missense_Mutation SNP C T uc003xli.2 WHSC1L1_uc011lb... Hybrid_Cap... view
WRN p.W85L 8 30921849 30921849 NCIH196_LUNG 37 Missense_Mutation SNP G T uc003xio.3 Hybrid_Cap... view
YES1 18 724333 724335 NCIH196_LUNG 37 3'UTR Del AAG - uc002kky.2 YES1_uc002kkz.2... Hybrid_Cap...
ZMYM2 p.T386A 13 20579236 20579236 NCIH196_LUNG 37 Missense_Mutation SNP A G uc001umr.2 ZMYM2_uc001umq.... Hybrid_Cap... view