Annotation Summary for Cell Line: NCI-H2029  

Cell line primary name: NCI-H2029
Cell line aliases: H2029
Gender: F
Site Primary: lung
Histology: carcinoma
Hist Subtype1: small_cell_carcinoma
Notes:
Source: ATCC
Expression arrays: AGENT_p_NCLE_RNA6_HG-U133_Plus_2_E05_436558
SNP arrays: LOBBY_p_NCLE_DNAAffy6_GenomeWideSNP_6_E10_437262
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in NCI-H2029

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ACACA 17 35766564 35766564 NCIH2029_LUNG 37 5'UTR Del A - uc002hno.2 ACACA_uc002hnn.... Hybrid_Cap...
ADAM17 2 9630245 9630245 NCIH2029_LUNG 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 NCIH2029_LUNG 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADAMTS20 p.Q1361H 12 43821135 43821135 NCIH2029_LUNG 37 Missense_Mutation SNP C G uc010skx.1 ADAMTS20_uc001r... Hybrid_Cap... view
AKAP4 p.K234* X 49958664 49958664 NCIH2029_LUNG 37 Nonsense_Mutation SNP T A uc004dow.1 AKAP4_uc004dov.... Hybrid_Cap... view
AKAP9 p.1335_1336insQ 7 91652178 91652179 NCIH2029_LUNG 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
AKT2 p.A190G 19 40747849 40747849 NCIH2029_LUNG 37 Missense_Mutation SNP G C uc002onf.2 AKT2_uc010egs.2... Hybrid_Cap... view
ALPK1 4 113347609 113347610 NCIH2029_LUNG 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 NCIH2029_LUNG 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
AURKC 19 57742494 57742507 NCIH2029_LUNG 37 5'UTR Del GGACG... - rs67926438;rs112039303;rs59094959 uc002qoe.2 AURKC_uc002qoc.... Hybrid_Cap...
BCR 22 23631813 23631814 NCIH2029_LUNG 37 Intron Ins - C rs66503844 uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BCR 22 23632777 23632778 NCIH2029_LUNG 37 Intron Ins - T uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BRDT p.L369P 1 92443849 92443849 NCIH2029_LUNG 37 Missense_Mutation SNP T C uc010osz.1 BRDT_uc001dok.3... Hybrid_Cap... view
BTG1 12 92537706 92537707 NCIH2029_LUNG 37 3'UTR Ins - T rs33983967 uc001tby.3 BTG1_uc001tbv.1... Hybrid_Cap...
CABC1 1 227171585 227171585 NCIH2029_LUNG 37 Intron Del T - uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CABC1 1 227171736 227171737 NCIH2029_LUNG 37 Intron Ins - T rs1574184 uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CASP9 1 15833611 15833611 NCIH2029_LUNG 37 Intron SNP C T uc001awn.2 CASP9_uc001awm.... Hybrid_Cap... view
CBL p.K424T 11 119149263 119149263 NCIH2029_LUNG 37 Missense_Mutation SNP A C uc001pwe.2 Hybrid_Cap... view
CDK11B 1 1654066 1654068 NCIH2029_LUNG 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 NCIH2029_LUNG 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
COL14A1 p.A157T 8 121209062 121209062 NCIH2029_LUNG 37 Missense_Mutation SNP G A uc003yox.2 COL14A1_uc003yo... Hybrid_Cap... view
COL18A1 p.T527M 21 46888384 46888384 NCIH2029_LUNG 37 Missense_Mutation SNP C T uc011afs.1 COL18A1_uc002zh... Hybrid_Cap... view
CREB3L2 p.T100del 7 137612914 137612916 NCIH2029_LUNG 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CSF1R 5 149433400 149433401 NCIH2029_LUNG 37 3'UTR Ins - C rs66970099;rs78449650 uc003lrl.2 CSF1R_uc011dcd.... Hybrid_Cap...
CSMD3 p.H1054Y 8 113662423 113662423 NCIH2029_LUNG 37 Missense_Mutation SNP G A uc003ynu.2 CSMD3_uc003yns.... Hybrid_Cap... view
CTNNA2 p.A868E 2 80874738 80874738 NCIH2029_LUNG 37 Missense_Mutation SNP C A uc010ysh.1 CTNNA2_uc010yse... Hybrid_Cap... view
DGKB p.G541A 7 14613988 14613988 NCIH2029_LUNG 37 Missense_Mutation SNP C G uc003ssz.2 DGKB_uc011jxt.1... Hybrid_Cap... view
DST p.M2309I 6 56437815 56437815 NCIH2029_LUNG 37 Missense_Mutation SNP C G uc003pdf.2 DST_uc003pcz.3_... Hybrid_Cap... view
ECM1 p.G23V 1 150480753 150480753 NCIH2029_LUNG 37 Missense_Mutation SNP G T uc001euu.2 ECM1_uc010pce.1... Hybrid_Cap... view
EIF3A p.I218V 10 120830487 120830487 NCIH2029_LUNG 37 Missense_Mutation SNP T C uc001ldu.2 EIF3A_uc010qsu.... Hybrid_Cap... view
EIF5A2 3 170611037 170611037 NCIH2029_LUNG 37 3'UTR SNP A G uc003fhd.2 Hybrid_Cap... view
EP300 22 41574970 41574972 NCIH2029_LUNG 37 3'UTR Del GTA - rs76489032 uc003azl.3 Hybrid_Cap...
EPHA6 3 97367230 97367231 NCIH2029_LUNG 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
EPHB1 p.A704G 3 134911646 134911646 NCIH2029_LUNG 37 Missense_Mutation SNP C G uc003eqt.2 EPHB1_uc003equ.... Hybrid_Cap... view
EPHB6 p.S116I 7 142561905 142561905 NCIH2029_LUNG 37 Missense_Mutation SNP G T uc011kst.1 EPHB6_uc011ksu.... Hybrid_Cap... view
ERBB3 p.N369S 12 56482649 56482649 NCIH2029_LUNG 37 Missense_Mutation SNP A G uc001sjh.2 ERBB3_uc009zoj.... Hybrid_Cap... view
ERBB4 p.E1100D 2 212251759 212251759 NCIH2029_LUNG 37 Missense_Mutation SNP C A uc002veg.1 ERBB4_uc002veh.... Hybrid_Cap... view
ETV5 p.A447V 3 185769916 185769916 NCIH2029_LUNG 37 Missense_Mutation SNP G A uc003fpy.2 ETV5_uc003fpz.2... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 NCIH2029_LUNG 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 NCIH2029_LUNG 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLI1 11 128638217 128638217 NCIH2029_LUNG 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLNA p.Y1511D X 153586880 153586880 NCIH2029_LUNG 37 Missense_Mutation SNP A C uc004fkk.2 FLNA_uc011mzn.1... Hybrid_Cap... view
FMN2 p.PPLPGAGIPPP939del 1 240370914 240370946 NCIH2029_LUNG 37 In_Frame_Del Del GCCCC... - rs4997328;rs4997329 uc010pye.1 FMN2_uc010pyd.1... Hybrid_Cap...
FN1 2 216244182 216244185 NCIH2029_LUNG 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GADD45A p.Q33E 1 68151760 68151760 NCIH2029_LUNG 37 Missense_Mutation SNP C G uc001ddz.1 GADD45A_uc009wb... Hybrid_Cap... view
GPR112 p.D2657del X 135474445 135474447 NCIH2029_LUNG 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 NCIH2029_LUNG 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 NCIH2029_LUNG 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HIF1A 14 62213929 62213930 NCIH2029_LUNG 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HNF1A 12 121434630 121434631 NCIH2029_LUNG 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
ILK 11 6630029 6630029 NCIH2029_LUNG 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
INHBA 7 41729122 41729122 NCIH2029_LUNG 37 3'UTR Del T - uc003thq.2 INHBA_uc003thr.... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 NCIH2029_LUNG 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KDR p.K939R 4 55961745 55961745 NCIH2029_LUNG 37 Missense_Mutation SNP T C uc003has.2 KDR_uc003hat.1_... Hybrid_Cap... view
KIAA2022 p.E228K X 73963710 73963710 NCIH2029_LUNG 37 Missense_Mutation SNP C T uc004eby.2 Hybrid_Cap... view
KLK7 19 51480672 51480675 NCIH2029_LUNG 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LATS2 13 21620222 21620223 NCIH2029_LUNG 37 5'UTR Ins - A rs61240127;rs115723063 uc009zzs.2 LATS2_uc001unr.... Hybrid_Cap...
LRP1B p.Q29L 2 142567967 142567967 NCIH2029_LUNG 37 Missense_Mutation SNP T A uc002tvj.1 LRP1B_uc010fnl.... Hybrid_Cap... view
LRRC7 p.A969V 1 70504527 70504527 NCIH2029_LUNG 37 Missense_Mutation SNP C T uc001dep.2 LRRC7_uc009wbg.... Hybrid_Cap... view
MAF 16 79632567 79632567 NCIH2029_LUNG 37 Intron SNP T A uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap... view
MAML2 p.604_607QQQQ>Q 11 95825375 95825383 NCIH2029_LUNG 37 In_Frame_Del Del TGCTG... - rs113349418 uc001pfw.1 Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 NCIH2029_LUNG 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 NCIH2029_LUNG 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K5 6 136878752 136878752 NCIH2029_LUNG 37 3'UTR Del T - rs79903899 uc003qhc.2 MAP3K5_uc011edj... Hybrid_Cap...
MFSD2A 1 40435515 40435515 NCIH2029_LUNG 37 3'UTR Del T - rs79314830 uc001cev.2 MFSD2A_uc001ceu... Hybrid_Cap...
MN1 p.544_546QQQ>Q 22 28194895 28194900 NCIH2029_LUNG 37 In_Frame_Del Del TGCTG... - rs75719175 uc003adj.2 Hybrid_Cap...
MSH3 p.PPA66del 5 79950742 79950750 NCIH2029_LUNG 37 In_Frame_Del Del CCCCC... - rs60484572;rs1047489 uc003kgz.2 DHFR_uc011ctl.1... Hybrid_Cap...
MTUS2 p.D161Y 13 29599286 29599286 NCIH2029_LUNG 37 Missense_Mutation SNP G T uc001usl.3 Hybrid_Cap... view
N4BP2 p.T1403A 4 40124755 40124755 NCIH2029_LUNG 37 Missense_Mutation SNP A G uc003guy.3 N4BP2_uc010ifq.... Hybrid_Cap... view
NCAM1 11 112832307 112832308 NCIH2029_LUNG 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 NCIH2029_LUNG 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA2 p.P1035L 8 71050492 71050492 NCIH2029_LUNG 37 Missense_Mutation SNP G A uc003xyn.1 NCOA2_uc011lfb.... Hybrid_Cap... view
NFIA 1 61921185 61921186 NCIH2029_LUNG 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NOS3 p.E206G 7 150695479 150695479 NCIH2029_LUNG 37 Missense_Mutation SNP A G uc003wif.2 NOS3_uc011kuy.1... Hybrid_Cap... view
NPM1 5 170837734 170837734 NCIH2029_LUNG 37 3'UTR Del T - uc011dex.1 NPM1_uc003mbi.2... Hybrid_Cap...
NPR1 1 153665919 153665920 NCIH2029_LUNG 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 NCIH2029_LUNG 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
PAX3 2 223158653 223158653 NCIH2029_LUNG 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAX5 9 37034095 37034095 NCIH2029_LUNG 37 5'UTR Del C - uc003zzo.1 PAX5_uc011lpw.1... Hybrid_Cap...
PDGFRA 4 55131002 55131002 NCIH2029_LUNG 37 Intron Del A - uc003han.3 PDGFRA_uc003haa... Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 NCIH2029_LUNG 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PTCH1 p.G854_splice 9 98224281 98224281 NCIH2029_LUNG 37 Splice_Site_SNP SNP C T uc004avk.3 PTCH1_uc010mro.... Hybrid_Cap... view
RB1 p.G89_splice 13 48916734 48916734 NCIH2029_LUNG 37 Splice_Site_SNP SNP G T uc001vcb.2 RB1_uc010acs.1_... Hybrid_Cap... view
RBM15 p.S158A 1 110882499 110882499 NCIH2029_LUNG 37 Missense_Mutation SNP T G uc001dzl.1 RBM15_uc001dzm.... Hybrid_Cap... view
RBPJ 4 26431822 26431822 NCIH2029_LUNG 37 Intron Del A - rs76214390 uc003grx.1 RBPJ_uc003gry.1... Hybrid_Cap...
RPS6KC1 p.T169P 1 213302902 213302902 NCIH2029_LUNG 37 Missense_Mutation SNP A C uc010ptr.1 RPS6KC1_uc001hk... Hybrid_Cap... view
RPS6KL1 14 75373626 75373627 NCIH2029_LUNG 37 3'UTR Ins - TGAT uc001xqx.1 RPS6KL1_uc001xq... Hybrid_Cap...
SERPINB4 p.W150C 18 61308127 61308127 NCIH2029_LUNG 37 Missense_Mutation SNP C A uc002ljf.2 SERPINB4_uc002l... Hybrid_Cap... view
SIK3 p.P1001S 11 116728862 116728862 NCIH2029_LUNG 37 Missense_Mutation SNP G A uc001ppy.2 SIK3_uc001ppz.2... Hybrid_Cap... view
SKIL p.T258S 3 170078892 170078892 NCIH2029_LUNG 37 Missense_Mutation SNP C G uc003fgu.2 SKIL_uc011bps.1... Hybrid_Cap... view
STK11 p.R310P 19 1222992 1222992 NCIH2029_LUNG 37 Missense_Mutation SNP G C uc002lrl.1 Hybrid_Cap... view
STK25 2 242435659 242435662 NCIH2029_LUNG 37 Intron Del AAGG - rs3215138;rs75497042 uc002wbm.2 STK25_uc002wbk.... Hybrid_Cap...
STK31 7 23872024 23872025 NCIH2029_LUNG 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TEC 4 48139307 48139310 NCIH2029_LUNG 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TLK1 2 171850178 171850179 NCIH2029_LUNG 37 3'UTR Ins - AA rs71008739 uc002ugo.2 TLK1_uc002ugn.2... Hybrid_Cap...
TMEM123 11 102269398 102269398 NCIH2029_LUNG 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TP53 p.Y220D 17 7578191 7578191 NCIH2029_LUNG 37 Missense_Mutation SNP A C uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TSC2 16 2138671 2138672 NCIH2029_LUNG 37 3'UTR Del AA - uc002con.2 TSC2_uc010bsd.2... Hybrid_Cap...
TTN 2 179391639 179391640 NCIH2029_LUNG 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.Y32102C 2 179397333 179397333 NCIH2029_LUNG 37 Missense_Mutation SNP T C uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.G13478E 2 179481479 179481479 NCIH2029_LUNG 37 Missense_Mutation SNP C T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 NCIH2029_LUNG 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
WNK2 p.P702L 9 96018651 96018651 NCIH2029_LUNG 37 Missense_Mutation SNP C T rs56062309 uc004ati.1 WNK2_uc011lud.1... Hybrid_Cap... view
WNT1 p.W167fs 12 49374347 49374348 NCIH2029_LUNG 37 Frame_Shift_Ins Ins - G uc001rsu.2 Hybrid_Cap...
ZAP70 2 98351655 98351655 NCIH2029_LUNG 37 Intron Del G - uc002syd.1 ZAP70_uc010yvf.... Hybrid_Cap...
ZAP70 p.S497L 2 98354227 98354227 NCIH2029_LUNG 37 Missense_Mutation SNP C T uc002syd.1 ZAP70_uc002sye.... Hybrid_Cap... view