Annotation Summary for Cell Line: NCI-H209  

Cell line primary name: NCI-H209
Cell line aliases: H-209 | H209
Gender: M
Site Primary: lung
Histology: carcinoma
Hist Subtype1: small_cell_carcinoma
Notes:
Source: ATCC
Expression arrays: METIS_p_NCLE_RNA1_Human_U133_Plus_2.0_A12_240872
SNP arrays: ARLES_p_NCLE_DNAAffy2_S_GenomeWideSNP_6_D07_256086
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in NCI-H209

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 NCIH209_LUNG 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ADAM17 2 9630245 9630245 NCIH209_LUNG 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 NCIH209_LUNG 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADCK1 p.T114T 14 78325541 78325541 NCIH209_LUNG 37 Silent SNP G A uc001xui.2 ADCK1_uc010tvo.... Hybrid_Cap... view
ADCK1 14 78390632 78390637 NCIH209_LUNG 37 Intron Del AAACT... - rs78274857;rs74969652 uc001xui.2 ADCK1_uc010tvo.... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 NCIH209_LUNG 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP6 p.I1657F 14 33291988 33291988 NCIH209_LUNG 37 Missense_Mutation SNP A T uc001wrq.2 Hybrid_Cap... view
AKAP9 p.1335_1336insQ 7 91652178 91652179 NCIH209_LUNG 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 NCIH209_LUNG 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
CABC1 1 227171585 227171585 NCIH209_LUNG 37 Intron Del T - uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CABC1 1 227171736 227171737 NCIH209_LUNG 37 Intron Ins - T rs1574184 uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CACNB2 10 18828721 18828722 NCIH209_LUNG 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 NCIH209_LUNG 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN6 3 1339681 1339686 NCIH209_LUNG 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
CSMD3 p.E3346_splice 8 113266556 113266556 NCIH209_LUNG 37 Splice_Site_SNP SNP C G uc003ynu.2 CSMD3_uc003yns.... Hybrid_Cap... view
CTSL2 p.R107C 9 99799611 99799611 NCIH209_LUNG 37 Missense_Mutation SNP G A uc004awt.2 CTSL2_uc010msi.... Hybrid_Cap... view
CUBN p.A2252V 10 16962028 16962028 NCIH209_LUNG 37 Missense_Mutation SNP G A uc001ioo.2 Hybrid_Cap... view
CYP3A4 p.S222P 7 99365983 99365983 NCIH209_LUNG 37 Missense_Mutation SNP A G rs55785340 uc003urv.1 CYP3A4_uc003urw... Hybrid_Cap... view
DST p.K282R 6 56566696 56566696 NCIH209_LUNG 37 Missense_Mutation SNP T C uc003pdf.2 DST_uc003pcz.3_... Hybrid_Cap... view
EIF2AK4 p.D872V 15 40282562 40282562 NCIH209_LUNG 37 Missense_Mutation SNP A T rs34665481 uc001zkm.1 EIF2AK4_uc010bb... Hybrid_Cap... view
EIF2AK4 15 40284510 40284510 NCIH209_LUNG 37 Intron SNP T G uc001zkm.1 EIF2AK4_uc010bb... Hybrid_Cap... view
EPHA10 p.R877* 1 38185213 38185213 NCIH209_LUNG 37 Nonsense_Mutation SNP G A uc009vvi.2 EPHA10_uc001cbt... Hybrid_Cap... view
EPHA6 3 97367230 97367231 NCIH209_LUNG 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
ETV1 7 14028708 14028708 NCIH209_LUNG 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
EXT1 8 118811807 118811807 NCIH209_LUNG 37 3'UTR Del T - uc003yok.1 Hybrid_Cap...
FCRL4 p.A477S 1 157548264 157548264 NCIH209_LUNG 37 Missense_Mutation SNP C A uc001fqw.2 FCRL4_uc010phy.... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 NCIH209_LUNG 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 NCIH209_LUNG 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLI1 11 128638217 128638217 NCIH209_LUNG 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FN1 2 216244182 216244185 NCIH209_LUNG 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GPR112 p.H2104D X 135432175 135432175 NCIH209_LUNG 37 Missense_Mutation SNP C G uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap... view
GPR112 p.D2657del X 135474445 135474447 NCIH209_LUNG 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 NCIH209_LUNG 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 NCIH209_LUNG 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HERC2 p.P2924A 15 28431778 28431778 NCIH209_LUNG 37 Missense_Mutation SNP G C uc001zbj.2 Hybrid_Cap... view
ICK p.S536R 6 52874250 52874250 NCIH209_LUNG 37 Missense_Mutation SNP G C rs55694702 uc003pbh.2 ICK_uc003pbi.2_... Hybrid_Cap... view
ILK 11 6630029 6630029 NCIH209_LUNG 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITGAV p.S924N 2 187540395 187540395 NCIH209_LUNG 37 Missense_Mutation SNP G A rs56316527 uc002upq.2 ITGAV_uc010frs.... Hybrid_Cap... view
ITPR2 p.R470_splice 12 26834804 26834805 NCIH209_LUNG 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KDSR p.V171A 18 61018218 61018218 NCIH209_LUNG 37 Missense_Mutation SNP A G uc010dpw.2 KDSR_uc010xem.1... Hybrid_Cap... view
KLK7 19 51480672 51480675 NCIH209_LUNG 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LIFR p.S151C 5 38523630 38523630 NCIH209_LUNG 37 Missense_Mutation SNP G C rs61751712 uc010ive.1 LIFR_uc003jli.2... Hybrid_Cap... view
LRP2 p.D3744E 2 170028556 170028556 NCIH209_LUNG 37 Missense_Mutation SNP G T uc002ues.2 Hybrid_Cap... view
MAF 16 79628537 79628537 NCIH209_LUNG 37 Intron Del T - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 NCIH209_LUNG 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 NCIH209_LUNG 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 NCIH209_LUNG 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAPKBP1 15 42111753 42111754 NCIH209_LUNG 37 Intron Ins - C rs3034891 uc001zok.3 MAPKBP1_uc001zo... Hybrid_Cap...
MARK1 p.A87fs 1 220754412 220754412 NCIH209_LUNG 37 Frame_Shift_Del Del T - uc009xdw.2 MARK1_uc001hml.... Hybrid_Cap...
MEN1 p.A242V 11 64575097 64575097 NCIH209_LUNG 37 Missense_Mutation SNP G A uc001obj.2 MEN1_uc001obk.2... Hybrid_Cap... view
MLL3 p.E3406K 7 151860446 151860446 NCIH209_LUNG 37 Missense_Mutation SNP C T uc003wla.2 MLL3_uc003wkz.2... Hybrid_Cap... view
MLLT3 p.V36L 9 20620740 20620740 NCIH209_LUNG 37 Missense_Mutation SNP C A uc003zoe.2 MLLT3_uc011lne.... Hybrid_Cap... view
MSH6 p.R1321G 2 48033750 48033750 NCIH209_LUNG 37 Missense_Mutation SNP A G rs41295278 uc002rwd.3 MSH6_uc010fbj.2... Hybrid_Cap... view
MST1R 3 49941058 49941058 NCIH209_LUNG 37 5'UTR SNP C A uc003cxy.3 MST1R_uc011bdd.... Hybrid_Cap... view
MYST4 p.E1104del 10 76781906 76781908 NCIH209_LUNG 37 In_Frame_Del Del GAA - rs79644703 uc001jwn.1 MYST4_uc001jwm.... Hybrid_Cap...
NCAM1 11 112832307 112832308 NCIH209_LUNG 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 NCIH209_LUNG 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 NCIH209_LUNG 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NEK9 p.S765G 14 75558122 75558122 NCIH209_LUNG 37 Missense_Mutation SNP T C uc001xrl.2 NEK9_uc001xrj.2... Hybrid_Cap... view
NOTCH1 p.Q1193H 9 139401821 139401821 NCIH209_LUNG 37 Missense_Mutation SNP C A rs61751544 uc004chz.2 NOTCH1_uc004cia... Hybrid_Cap... view
NPRL2 p.P28L 3 50387449 50387449 NCIH209_LUNG 37 Missense_Mutation SNP G A uc003daj.1 NPRL2_uc003dai.... Hybrid_Cap... view
NR1H2 p.176_177insQ 19 50881820 50881821 NCIH209_LUNG 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NUMA1 p.R692S 11 71726473 71726473 NCIH209_LUNG 37 Missense_Mutation SNP C G uc001orl.1 NUMA1_uc009ysw.... Hybrid_Cap... view
PAX3 2 223158653 223158653 NCIH209_LUNG 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PDGFRA 4 55131277 55131277 NCIH209_LUNG 37 Intron SNP A G uc003han.3 PDGFRA_uc003haa... Hybrid_Cap... view
PI4KB 1 151298726 151298726 NCIH209_LUNG 37 Splice_Site_SNP SNP T C uc001exr.2 PI4KB_uc001exs.... Hybrid_Cap... view
PIK3C2G p.K871M 12 18641490 18641490 NCIH209_LUNG 37 Missense_Mutation SNP A T uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap... view
PMS1 2 190670539 190670540 NCIH209_LUNG 37 Intron Ins - A rs3214425 uc002urh.3 PMS1_uc010zga.1... Hybrid_Cap...
PRKAR1B p.V30I 7 751055 751055 NCIH209_LUNG 37 Missense_Mutation SNP C T uc003siu.1 PRKAR1B_uc003si... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 NCIH209_LUNG 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PTPRT p.R790I 20 40877327 40877327 NCIH209_LUNG 37 Missense_Mutation SNP C A uc010ggj.2 PTPRT_uc002xkg.... Hybrid_Cap... view
RABEP1 17 5281724 5281724 NCIH209_LUNG 37 Intron Del A - uc002gbm.3 RABEP1_uc010cld... Hybrid_Cap...
RAPGEF2 4 160189224 160189224 NCIH209_LUNG 37 5'UTR SNP A T uc003iqg.3 Hybrid_Cap... view
RB1 p.C706F 13 49037877 49037877 NCIH209_LUNG 37 Missense_Mutation SNP G T uc001vcb.2 Hybrid_Cap... view
RECQL4 p.R766fs 8 145738768 145738768 NCIH209_LUNG 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RGL2 p.R337H 6 33263295 33263295 NCIH209_LUNG 37 Missense_Mutation SNP C T rs61758744 uc003odv.2 RGL2_uc003odu.2... Hybrid_Cap... view
ROBO2 p.D1018E 3 77651548 77651548 NCIH209_LUNG 37 Missense_Mutation SNP T A uc003dpz.2 ROBO2_uc003dpy.... Hybrid_Cap... view
RPS6KL1 14 75373626 75373627 NCIH209_LUNG 37 3'UTR Ins - TGAT uc001xqx.1 RPS6KL1_uc001xq... Hybrid_Cap...
STK31 7 23872024 23872025 NCIH209_LUNG 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TBX18 p.S603Y 6 85446419 85446419 NCIH209_LUNG 37 Missense_Mutation SNP G T uc003pkl.1 TBX18_uc010kbq.... Hybrid_Cap... view
TET2 p.L328R 4 106156019 106156019 NCIH209_LUNG 37 Missense_Mutation SNP T G uc011cez.1 TET2_uc003hxk.2... Hybrid_Cap... view
TIAM1 p.K206Q 21 32638673 32638673 NCIH209_LUNG 37 Missense_Mutation SNP T G uc002yow.1 TIAM1_uc011adk.... Hybrid_Cap... view
TMEM123 11 102269461 102269461 NCIH209_LUNG 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TMPO p.K196fs 12 98926622 98926626 NCIH209_LUNG 37 Frame_Shift_Del Del AAGTG - uc001tfh.1 TMPO_uc001tfi.1... Hybrid_Cap...
TNFRSF10B p.G250_splice 8 22885843 22885843 NCIH209_LUNG 37 Splice_Site_SNP SNP C T rs41308110 uc003xcu.2 TNFRSF10B_uc003... Hybrid_Cap... view
TP53 p.V225_splice 17 7577610 7577610 NCIH209_LUNG 37 Splice_Site_SNP SNP T A uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TP63 3 189507518 189507519 NCIH209_LUNG 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TRIM33 1 114940215 114940216 NCIH209_LUNG 37 3'UTR Ins - G rs68133208 uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TRIM36 p.273_274QV>HL 5 114477023 114477024 NCIH209_LUNG 37 Missense_Mutation DNP CC AA uc003kqs.2 TRIM36_uc011cwc... Hybrid_Cap...
TRPS1 8 116635872 116635873 NCIH209_LUNG 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TTBK2 p.D635G 15 43067427 43067427 NCIH209_LUNG 37 Missense_Mutation SNP T C uc001zqo.2 TTBK2_uc010bcy.... Hybrid_Cap... view
TTN p.Q12943H 2 179484511 179484511 NCIH209_LUNG 37 Missense_Mutation SNP T A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 NCIH209_LUNG 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
VPS13B p.C1174* 8 100479718 100479718 NCIH209_LUNG 37 Nonsense_Mutation SNP C A uc003yiv.2 VPS13B_uc003yiw... Hybrid_Cap... view
WNK1 p.R2380W 12 1017947 1017947 NCIH209_LUNG 37 Missense_Mutation SNP C T rs56262445 uc001qio.3 WNK1_uc001qip.3... Hybrid_Cap... view
ZAP70 2 98351655 98351655 NCIH209_LUNG 37 Intron Del G - uc002syd.1 ZAP70_uc010yvf.... Hybrid_Cap...