Annotation Summary for Cell Line: NCI-H2171  

Cell line primary name: NCI-H2171
Cell line aliases: H2171 | H-2171
Gender: M
Site Primary: lung
Histology: carcinoma
Hist Subtype1: small_cell_carcinoma
Notes:
Source: ATCC
Expression arrays: METIS_p_NCLE_RNA1_Human_U133_Plus_2.0_D03_240926
SNP arrays: LIMPS_p_NCLE_DNA2N_GenomeWideSNP_6_D03_246686
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in NCI-H2171

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ABCC3 17 48740901 48740901 NCIH2171_LUNG 37 Intron SNP C T uc002isl.2 ABCC3_uc002isk.... Hybrid_Cap... view
ACACA 17 35766564 35766564 NCIH2171_LUNG 37 5'UTR Del A - uc002hno.2 ACACA_uc002hnn.... Hybrid_Cap...
ADAM17 2 9630245 9630245 NCIH2171_LUNG 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM22 p.G393R 7 87762210 87762210 NCIH2171_LUNG 37 Missense_Mutation SNP G A uc003ujp.1 ADAM22_uc003ujk... Hybrid_Cap... view
ADAM28 8 24211994 24211997 NCIH2171_LUNG 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADAMTS20 p.G1888S 12 43748083 43748083 NCIH2171_LUNG 37 Missense_Mutation SNP C T rs61748366 uc010skx.1 Hybrid_Cap... view
AKAP12 p.1531_1532insE 6 151674116 151674117 NCIH2171_LUNG 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ALPK2 p.1388_1389FF>F 18 56203253 56203255 NCIH2171_LUNG 37 In_Frame_Del Del AAG - uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
BAI3 p.V995A 6 70037730 70037730 NCIH2171_LUNG 37 Missense_Mutation SNP T C uc003pev.3 BAI3_uc010kak.2... Hybrid_Cap... view
C15ORF2 p.P1156Q 15 24924481 24924481 NCIH2171_LUNG 37 Missense_Mutation SNP C A uc001ywo.2 Hybrid_Cap... view
CACNB2 10 18828721 18828722 NCIH2171_LUNG 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CDC5L p.G479W 6 44392186 44392186 NCIH2171_LUNG 37 Missense_Mutation SNP G T uc003oxl.2 Hybrid_Cap... view
CHD1 p.P1684del 5 98192165 98192167 NCIH2171_LUNG 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CHD5 p.R1306L 1 6186793 6186793 NCIH2171_LUNG 37 Missense_Mutation SNP C A uc001amb.1 CHD5_uc001alz.1... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 NCIH2171_LUNG 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN6 3 1339718 1339718 NCIH2171_LUNG 37 Intron Del T - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
CSMD3 p.L3444I 8 113256695 113256695 NCIH2171_LUNG 37 Missense_Mutation SNP A T uc003ynu.2 CSMD3_uc003yns.... Hybrid_Cap... view
CTBP2 p.K974fs 10 126678123 126678123 NCIH2171_LUNG 37 Frame_Shift_Del Del T - uc001lie.3 CTBP2_uc009yak.... Hybrid_Cap...
DACH1 13 72014625 72014626 NCIH2171_LUNG 37 3'UTR Ins - T rs117109529 uc010thn.1 DACH1_uc010tho.... Hybrid_Cap...
DOCK3 p.R1558H 3 51394562 51394562 NCIH2171_LUNG 37 Missense_Mutation SNP G A uc011bds.1 Hybrid_Cap... view
DRD2 p.D178_splice 11 113287584 113287584 NCIH2171_LUNG 37 Splice_Site_SNP SNP C A uc001pnz.2 DRD2_uc010rwv.1... Hybrid_Cap... view
DYRK1A 21 38884966 38884967 NCIH2171_LUNG 37 3'UTR Ins - T rs72430212 uc002ywk.2 DYRK1A_uc002ywi... Hybrid_Cap...
ECM1 1 150482724 150482724 NCIH2171_LUNG 37 Intron SNP G A uc001euu.2 ECM1_uc010pce.1... Hybrid_Cap... view
EIF4E 4 99808137 99808141 NCIH2171_LUNG 37 Intron Del TTAAA - uc011ceb.1 EIF4E_uc011cea.... Hybrid_Cap...
EPHA4 2 222290611 222290611 NCIH2171_LUNG 37 3'UTR SNP G A uc002vmq.2 EPHA4_uc002vmr.... Hybrid_Cap... view
ETV1 7 14028708 14028708 NCIH2171_LUNG 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FAM132A 1 1177919 1177919 NCIH2171_LUNG 37 3'UTR Del T - uc001adl.1 Hybrid_Cap...
FGFR1OP 6 167453519 167453520 NCIH2171_LUNG 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 NCIH2171_LUNG 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLI1 11 128638217 128638217 NCIH2171_LUNG 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLT1 p.N596S 13 28964115 28964115 NCIH2171_LUNG 37 Missense_Mutation SNP T C uc001usb.3 FLT1_uc010aar.1... Hybrid_Cap... view
GOLGA5 14 93305838 93305838 NCIH2171_LUNG 37 3'UTR SNP G A uc001yaz.1 GOLGA5_uc001yba... Hybrid_Cap... view
GPR87 3 151011905 151011906 NCIH2171_LUNG 37 3'UTR Ins - AAACATTTA uc003eyt.2 MED12L_uc011bnz... Hybrid_Cap...
GRIA3 X 122318386 122318387 NCIH2171_LUNG 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
HNF1A p.T327I 12 121434089 121434089 NCIH2171_LUNG 37 Missense_Mutation SNP C T uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap... view
ILK 11 6630029 6630029 NCIH2171_LUNG 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITGB6 p.N195Y 2 161051890 161051890 NCIH2171_LUNG 37 Missense_Mutation SNP T A uc002ubh.2 ITGB6_uc010fow.... Hybrid_Cap... view
ITPR2 p.R470_splice 12 26834804 26834805 NCIH2171_LUNG 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KIAA1409 p.S2042I 14 94125555 94125555 NCIH2171_LUNG 37 Missense_Mutation SNP G T uc001ybv.1 KIAA1409_uc001y... Hybrid_Cap... view
KLK7 19 51480672 51480675 NCIH2171_LUNG 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LRRK2 p.G2218W 12 40748176 40748176 NCIH2171_LUNG 37 Missense_Mutation SNP G T uc001rmg.3 LRRK2_uc009zjw.... Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 NCIH2171_LUNG 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 NCIH2171_LUNG 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 NCIH2171_LUNG 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MTUS2 p.G946R 13 29856002 29856002 NCIH2171_LUNG 37 Missense_Mutation SNP G A uc001usl.3 Hybrid_Cap... view
NCAM1 11 112832307 112832308 NCIH2171_LUNG 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 NCIH2171_LUNG 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NPR1 1 153665919 153665920 NCIH2171_LUNG 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 NCIH2171_LUNG 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NTRK3 p.G473C 15 88576256 88576256 NCIH2171_LUNG 37 Missense_Mutation SNP C A uc002bme.1 NTRK3_uc002bmh.... Hybrid_Cap... view
OLFM4 p.L440P 13 53624692 53624692 NCIH2171_LUNG 37 Missense_Mutation SNP T C uc001vhl.2 OLFM4_uc001vhk.... Hybrid_Cap... view
PAX3 2 223158653 223158653 NCIH2171_LUNG 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAXIP1 p.Q349H 7 154767433 154767433 NCIH2171_LUNG 37 Missense_Mutation SNP C A uc003wlp.2 PAXIP1_uc003wlq... Hybrid_Cap... view
PCDH15 p.E548fs 10 55913017 55913017 NCIH2171_LUNG 37 Frame_Shift_Del Del C - uc010qhy.1 PCDH15_uc010qhq... Hybrid_Cap...
PPP3CB p.R469Q 10 75198172 75198172 NCIH2171_LUNG 37 Missense_Mutation SNP C T rs61749234 uc001juf.2 PPP3CB_uc001jue... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 NCIH2171_LUNG 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PRKG1 p.E148D 10 52913056 52913056 NCIH2171_LUNG 37 Missense_Mutation SNP A T uc001jjo.2 PRKG1_uc001jjm.... Hybrid_Cap... view
PTPRD p.D154Y 9 8528672 8528672 NCIH2171_LUNG 37 Missense_Mutation SNP C A uc003zkk.2 PTPRD_uc003zkp.... Hybrid_Cap... view
RB1 p.S567* 13 49027133 49027133 NCIH2171_LUNG 37 Nonsense_Mutation SNP C A uc001vcb.2 Hybrid_Cap... view
ROR2 p.E357* 9 94493306 94493306 NCIH2171_LUNG 37 Nonsense_Mutation SNP C A uc004arj.1 ROR2_uc004ari.1... Hybrid_Cap... view
SACS p.N2380K 13 23910875 23910875 NCIH2171_LUNG 37 Missense_Mutation SNP A T rs61754478 uc001uon.2 SACS_uc001uoo.2... Hybrid_Cap... view
STK31 7 23872024 23872025 NCIH2171_LUNG 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TAF1L p.G47A 9 32635438 32635438 NCIH2171_LUNG 37 Missense_Mutation SNP C G uc003zrg.1 Hybrid_Cap... view
TGFBR1 p.I339fs 9 101907057 101907058 NCIH2171_LUNG 37 Frame_Shift_Ins Ins - T uc004azc.2 TGFBR1_uc004azd... Hybrid_Cap...
TNFAIP3 p.R761H 6 138202365 138202365 NCIH2171_LUNG 37 Missense_Mutation SNP G A uc003qhr.2 TNFAIP3_uc003qh... Hybrid_Cap... view
TNRC6B p.Q1328del 22 40697177 40697179 NCIH2171_LUNG 37 In_Frame_Del Del GCA - rs114291931 uc011aor.1 TNRC6B_uc003aym... Hybrid_Cap...
TP53 p.Q144* 17 7578500 7578500 NCIH2171_LUNG 37 Nonsense_Mutation SNP G A uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TRIM42 p.S385R 3 140406679 140406679 NCIH2171_LUNG 37 Missense_Mutation SNP C A uc003eto.1 Hybrid_Cap... view
TTN 2 179391639 179391640 NCIH2171_LUNG 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.D25916Y 2 179425409 179425409 NCIH2171_LUNG 37 Missense_Mutation SNP C A rs56330345 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
XPO4 p.L499F 13 21382717 21382717 NCIH2171_LUNG 37 Missense_Mutation SNP T A uc001unq.3 Hybrid_Cap... view
ZNF521 p.D187H 18 22807323 22807323 NCIH2171_LUNG 37 Missense_Mutation SNP C G uc002kvk.2 ZNF521_uc010xbe... Hybrid_Cap... view