Annotation Summary for Cell Line: NCI-H226  

Cell line primary name: NCI-H226
Cell line aliases: H226
Gender: M
Site Primary: lung
Histology: carcinoma
Hist Subtype1: squamous_cell_carcinoma
Notes:
Source: ATCC
Expression arrays: AGENT_p_NCLE_RNA6_HG-U133_Plus_2_G06_436504
SNP arrays: PODIA_p_NCLE_DNAAffy7_GenomeWideSNP_6_F02_437454
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in NCI-H226

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 NCIH226_LUNG 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ACACA 17 35766564 35766564 NCIH226_LUNG 37 5'UTR Del A - uc002hno.2 ACACA_uc002hnn.... Hybrid_Cap...
ADAM17 2 9630245 9630245 NCIH226_LUNG 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 NCIH226_LUNG 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 NCIH226_LUNG 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP9 p.1335_1336insQ 7 91652178 91652179 NCIH226_LUNG 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ALPK1 4 113347609 113347610 NCIH226_LUNG 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
ALPK2 p.1388_1389FF>F 18 56203253 56203255 NCIH226_LUNG 37 In_Frame_Del Del AAG - uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 NCIH226_LUNG 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
APC p.I1177M 5 112174822 112174822 NCIH226_LUNG 37 Missense_Mutation SNP T G uc010jby.2 APC_uc011cvt.1_... Hybrid_Cap... view
BMP4 p.P73L 14 54418723 54418723 NCIH226_LUNG 37 Missense_Mutation SNP G A uc001xal.3 BMP4_uc010aoh.2... Hybrid_Cap... view
BTG1 12 92537706 92537707 NCIH226_LUNG 37 3'UTR Ins - T rs33983967 uc001tby.3 BTG1_uc001tbv.1... Hybrid_Cap...
CACNB2 10 18828721 18828722 NCIH226_LUNG 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CARD10 p.KE272del 22 37906309 37906314 NCIH226_LUNG 37 In_Frame_Del Del CTCCT... - uc003asx.1 CARD10_uc003ast... Hybrid_Cap...
CASP10 p.P228L 2 202060670 202060670 NCIH226_LUNG 37 Missense_Mutation SNP C T uc002uxj.1 CASP10_uc002uxi... Hybrid_Cap... view
CHD1 p.P1684del 5 98192165 98192167 NCIH226_LUNG 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 NCIH226_LUNG 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
DFNA5 7 24783982 24783982 NCIH226_LUNG 37 Intron Del C - uc010kus.1 DFNA5_uc003swz.... Hybrid_Cap...
DNAH8 6 38952247 38952250 NCIH226_LUNG 37 Intron Del CACA - uc003ooe.1 DNAH8_uc003oog.... Hybrid_Cap...
DYRK1A 21 38884966 38884967 NCIH226_LUNG 37 3'UTR Ins - T rs72430212 uc002ywk.2 DYRK1A_uc002ywi... Hybrid_Cap...
EIF2AK4 15 40284251 40284251 NCIH226_LUNG 37 Intron SNP A G uc001zkm.1 EIF2AK4_uc010bb... Hybrid_Cap... view
EP300 22 41574970 41574972 NCIH226_LUNG 37 3'UTR Del GTA - rs76489032 uc003azl.3 Hybrid_Cap...
EPHA5 4 66189753 66189754 NCIH226_LUNG 37 3'UTR Ins - T rs67487372 uc011cah.1 EPHA5_uc003hcx.... Hybrid_Cap...
ERCC3 2 128047098 128047098 NCIH226_LUNG 37 Intron SNP G A uc002toh.1 ERCC3_uc002toe.... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 NCIH226_LUNG 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FLI1 11 128638217 128638217 NCIH226_LUNG 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FZD1 p.93_94insP 7 90894459 90894460 NCIH226_LUNG 37 In_Frame_Ins Ins - CCG uc003ula.2 Hybrid_Cap...
GPR112 p.D2657del X 135474445 135474447 NCIH226_LUNG 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 NCIH226_LUNG 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GRIN2B p.G427R 12 13769438 13769438 NCIH226_LUNG 37 Missense_Mutation SNP C G uc001rbt.2 Hybrid_Cap... view
HNF1A 12 121434630 121434631 NCIH226_LUNG 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
IGF1R 15 99192755 99192763 NCIH226_LUNG 37 5'UTR Del TTTTT... - uc002bul.2 IGF1R_uc010urq.... Hybrid_Cap...
ILK 11 6630029 6630029 NCIH226_LUNG 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
INPP5D p.V683L 2 234085968 234085968 NCIH226_LUNG 37 Missense_Mutation SNP G T uc010zmo.1 INPP5D_uc010zmp... Hybrid_Cap... view
JAG2 p.N676K 14 105614769 105614769 NCIH226_LUNG 37 Missense_Mutation SNP G C uc001yqg.2 JAG2_uc010axf.2... Hybrid_Cap... view
KLK7 19 51480672 51480675 NCIH226_LUNG 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LIMK2 p.R182G 22 31658175 31658175 NCIH226_LUNG 37 Missense_Mutation SNP C G uc003akj.2 LIMK2_uc003akg.... Hybrid_Cap... view
LRP1 12 57606493 57606493 NCIH226_LUNG 37 3'UTR SNP G A uc001snd.2 Hybrid_Cap... view
MAF 16 79628537 79628537 NCIH226_LUNG 37 Intron Del T - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 NCIH226_LUNG 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 NCIH226_LUNG 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 NCIH226_LUNG 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MBIP p.I79I 14 36785911 36785911 NCIH226_LUNG 37 Silent SNP A G uc001wtm.2 MBIP_uc001wto.2... Hybrid_Cap... view
MCM3AP p.S46F 21 47705064 47705064 NCIH226_LUNG 37 Missense_Mutation SNP G A uc002zir.1 C21orf57_uc002z... Hybrid_Cap... view
MLLT6 17 36881873 36881873 NCIH226_LUNG 37 3'UTR Del C - uc002hqi.3 MLLT6_uc002hqk.... Hybrid_Cap...
MUSK p.K69_splice 9 113445078 113445081 NCIH226_LUNG 37 Splice_Site_Del Del TAAG - uc004bey.2 MUSK_uc004bex.2... Hybrid_Cap...
NCAM1 11 112832307 112832308 NCIH226_LUNG 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 NCIH226_LUNG 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 NCIH226_LUNG 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NFKBIA 14 35871136 35871138 NCIH226_LUNG 37 3'UTR Del TTC - rs112369437 uc001wtf.3 NFKBIA_uc001wte... Hybrid_Cap...
NPR1 1 153665919 153665920 NCIH226_LUNG 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 NCIH226_LUNG 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 NCIH226_LUNG 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
OBSCN p.R5725C 1 228526642 228526642 NCIH226_LUNG 37 Missense_Mutation SNP C T uc009xez.1 OBSCN_uc001hsn.... Hybrid_Cap... view
P2RX7 p.C572S 12 121622532 121622532 NCIH226_LUNG 37 Missense_Mutation SNP G C uc001tzm.2 P2RX7_uc001tzn.... Hybrid_Cap... view
PAX3 2 223158653 223158653 NCIH226_LUNG 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PDE4DIP p.E1147K 1 144882580 144882581 NCIH226_LUNG 37 Missense_Mutation DNP CA TG rs1699836 uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDE4DIP 1 144902984 144902984 NCIH226_LUNG 37 Intron SNP G A uc001elw.3 NBPF10_uc009wir... Hybrid_Cap... view
PGGT1B 5 114548071 114548072 NCIH226_LUNG 37 3'UTR Ins - C uc003kqw.3 PGGT1B_uc003kqx... Hybrid_Cap...
PIK3C2G p.P129del 12 18435399 18435401 NCIH226_LUNG 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PPP1R3A p.P39R 7 113558936 113558936 NCIH226_LUNG 37 Missense_Mutation SNP G C uc010ljy.1 Hybrid_Cap... view
PRKCA 17 64298959 64298960 NCIH226_LUNG 37 5'UTR Ins - G rs71160558 uc002jfp.1 PRKCA_uc002jfo.... Hybrid_Cap...
PRKD3 2 37480319 37480320 NCIH226_LUNG 37 Stop_Codon_Ins Ins - T rs79875666 uc002rqd.2 Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 NCIH226_LUNG 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PRKG1 10 52751088 52751089 NCIH226_LUNG 37 5'UTR Ins - GCT rs67900156;rs71029335 uc001jjm.2 PRKG1_uc010qhp.... Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 NCIH226_LUNG 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
ROBO1 p.T730M 3 78710311 78710311 NCIH226_LUNG 37 Missense_Mutation SNP G A uc003dqe.2 ROBO1_uc003dqb.... Hybrid_Cap... view
ROCK1 18 18531288 18531288 NCIH226_LUNG 37 3'UTR SNP A C uc002kte.2 Hybrid_Cap... view
RPS6KL1 14 75373626 75373627 NCIH226_LUNG 37 3'UTR Ins - TGAT uc001xqx.1 RPS6KL1_uc001xq... Hybrid_Cap...
SCYL1 p.V50V 11 65293083 65293083 NCIH226_LUNG 37 Silent SNP G C uc001oea.1 SCYL1_uc009yqk.... Hybrid_Cap... view
STRADA 17 61781331 61781332 NCIH226_LUNG 37 Intron Ins - AGAACC rs66701913 uc002jbm.2 STRADA_uc002jbn... Hybrid_Cap...
TACC3 4 1739519 1739527 NCIH226_LUNG 37 Intron Del GCCAT... - rs114226356 uc003gdo.2 TACC3_uc010ibz.... Hybrid_Cap...
TAF15 p.RSGGGYGGD450del 17 34171624 34171650 NCIH226_LUNG 37 In_Frame_Del Del AGAAG... - uc002hkd.2 TAF15_uc002hkc.... Hybrid_Cap...
TLE1 9 84202841 84202842 NCIH226_LUNG 37 Intron Ins - TCATCCCGCC rs60109467 uc004alz.2 TLE1_uc004aly.2... Hybrid_Cap...
TMEM123 11 102269398 102269398 NCIH226_LUNG 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TMEM123 11 102269461 102269461 NCIH226_LUNG 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TRIM33 1 114940215 114940216 NCIH226_LUNG 37 3'UTR Ins - G rs68133208 uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TRPS1 8 116635872 116635873 NCIH226_LUNG 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TTN p.G24241S 2 179430434 179430434 NCIH226_LUNG 37 Missense_Mutation SNP C T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 NCIH226_LUNG 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
YSK4 p.P162S 2 135756398 135756398 NCIH226_LUNG 37 Missense_Mutation SNP G A uc002tue.1 YSK4_uc010fne.1... Hybrid_Cap... view