Annotation Summary for Cell Line: NCI-H2405  

Cell line primary name: NCI-H2405
Cell line aliases: H2405
Gender: M
Site Primary: lung
Histology: carcinoma
Hist Subtype1: adenocarcinoma
Notes:
Source: ATCC
Expression arrays: WATCH_p_NCLE_RNA8_HG-U133_Plus_2_B12_474708
SNP arrays: MISTS_p_NCLE_DNAAffy11_GenomeWideSNP_6_B11_578340
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in NCI-H2405

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ADAM17 2 9630245 9630245 NCIH2405_LUNG 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 NCIH2405_LUNG 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ALPK2 p.1388_1389FF>F 18 56203253 56203255 NCIH2405_LUNG 37 In_Frame_Del Del AAG - uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ATP10A p.D534N 15 25962053 25962053 NCIH2405_LUNG 37 Missense_Mutation SNP C T uc010ayu.2 Hybrid_Cap... view
AURKC 19 57742494 57742507 NCIH2405_LUNG 37 5'UTR Del GGACG... - rs67926438;rs112039303;rs59094959 uc002qoe.2 AURKC_uc002qoc.... Hybrid_Cap...
CDK15 p.V400_splice 2 202744892 202744892 NCIH2405_LUNG 37 Splice_Site_SNP SNP T C uc002uyt.2 CDK15_uc002uys.... Hybrid_Cap... view
CHD1 p.P1684del 5 98192165 98192167 NCIH2405_LUNG 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CHD8 14 21853630 21853630 NCIH2405_LUNG 37 3'UTR Del T - rs78520772 uc001was.1 CHD8_uc001war.1... Hybrid_Cap...
CIC p.P952S 19 42795865 42795865 NCIH2405_LUNG 37 Missense_Mutation SNP C T uc002otf.1 Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 NCIH2405_LUNG 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CREB3L2 p.T100del 7 137612914 137612916 NCIH2405_LUNG 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CSMD3 p.G3469R 8 113254012 113254012 NCIH2405_LUNG 37 Missense_Mutation SNP C G uc003ynu.2 CSMD3_uc003yns.... Hybrid_Cap... view
CXCL12 10 44873992 44873993 NCIH2405_LUNG 37 Intron Ins - CT rs117617571 uc001jbh.2 CXCL12_uc001jbf... Hybrid_Cap...
EPHA8 1 22915892 22915895 NCIH2405_LUNG 37 Intron Del TAAG - uc001bfx.1 EPHA8_uc001bfw.... Hybrid_Cap...
ERCC5 p.E1106V 13 103528009 103528009 NCIH2405_LUNG 37 Missense_Mutation SNP A T uc001vpw.2 Hybrid_Cap... view
ETV1 7 14028708 14028708 NCIH2405_LUNG 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FBN1 p.D1191N 15 48779290 48779290 NCIH2405_LUNG 37 Missense_Mutation SNP C T uc001zwx.1 Hybrid_Cap... view
FBN2 5 127595046 127595048 NCIH2405_LUNG 37 3'UTR Del TTA - uc003kuu.2 Hybrid_Cap...
FLI1 11 128638217 128638217 NCIH2405_LUNG 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FN1 2 216244182 216244185 NCIH2405_LUNG 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
FZD1 p.93_94insP 7 90894459 90894460 NCIH2405_LUNG 37 In_Frame_Ins Ins - CCG uc003ula.2 Hybrid_Cap...
GLYATL2 11 58601858 58601858 NCIH2405_LUNG 37 3'UTR Del T - uc001nnd.3 GLYATL2_uc009ym... Hybrid_Cap...
GRIA3 X 122318386 122318387 NCIH2405_LUNG 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GTSE1 22 46722631 46722631 NCIH2405_LUNG 37 Intron SNP C T uc011aqy.1 GTSE1_uc011aqz.... Hybrid_Cap... view
GUCY2C 12 14827464 14827466 NCIH2405_LUNG 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HAPLN1 p.Y348C 5 82937337 82937337 NCIH2405_LUNG 37 Missense_Mutation SNP T C uc003kim.2 HAPLN1_uc003kin... Hybrid_Cap... view
HNF1A 12 121434630 121434631 NCIH2405_LUNG 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
HSP90B1 p.E791del 12 104341188 104341190 NCIH2405_LUNG 37 In_Frame_Del Del GAA - rs117491163 uc001tkb.1 HSP90B1_uc010sw... Hybrid_Cap...
IL21R 16 27460779 27460780 NCIH2405_LUNG 37 3'UTR Ins - TG rs66690088 uc002doq.1 IL21R_uc002dor.... Hybrid_Cap...
ILK 11 6630029 6630029 NCIH2405_LUNG 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITGAV p.A570V 2 187521118 187521118 NCIH2405_LUNG 37 Missense_Mutation SNP C T uc002upq.2 ITGAV_uc010frs.... Hybrid_Cap... view
KLK7 19 51480672 51480675 NCIH2405_LUNG 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LIFR p.G818L 5 38485965 38485966 NCIH2405_LUNG 37 Missense_Mutation DNP CC AA uc010ive.1 LIFR_uc003jli.2... Hybrid_Cap...
MAML2 p.604_607QQQQ>Q 11 95825375 95825383 NCIH2405_LUNG 37 In_Frame_Del Del TGCTG... - rs113349418 uc001pfw.1 Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 NCIH2405_LUNG 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 NCIH2405_LUNG 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 NCIH2405_LUNG 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAPKBP1 15 42111746 42111746 NCIH2405_LUNG 37 Intron Del G - uc001zok.3 MAPKBP1_uc001zo... Hybrid_Cap...
MAPKBP1 15 42111753 42111754 NCIH2405_LUNG 37 Intron Ins - C rs3034891 uc001zok.3 MAPKBP1_uc001zo... Hybrid_Cap...
MEF2A p.Q430del 15 100252710 100252712 NCIH2405_LUNG 37 In_Frame_Del Del CAG - uc010urw.1 MEF2A_uc010urv.... Hybrid_Cap...
MLLT6 17 36881873 36881873 NCIH2405_LUNG 37 3'UTR Del C - uc002hqi.3 MLLT6_uc002hqk.... Hybrid_Cap...
MYCL1 p.P259H 1 40363363 40363363 NCIH2405_LUNG 37 Missense_Mutation SNP G T uc001cer.1 MYCL1_uc001ces.... Hybrid_Cap... view
MYLK p.P203Q 3 123456371 123456371 NCIH2405_LUNG 37 Missense_Mutation SNP G T uc003ego.2 MYLK_uc011bjw.1... Hybrid_Cap... view
MYST4 p.E1104del 10 76781906 76781908 NCIH2405_LUNG 37 In_Frame_Del Del GAA - rs79644703 uc001jwn.1 MYST4_uc001jwm.... Hybrid_Cap...
MYT1 20 62871868 62871868 NCIH2405_LUNG 37 3'UTR SNP G A uc002yii.2 MYT1_uc002yij.2... Hybrid_Cap... view
NCAM1 11 112832307 112832308 NCIH2405_LUNG 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 NCIH2405_LUNG 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 NCIH2405_LUNG 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NOS2 p.S81Y 17 26115911 26115911 NCIH2405_LUNG 37 Missense_Mutation SNP G T uc002gzu.2 NOS2_uc010crh.1... Hybrid_Cap... view
NR1H2 p.176_177insQ 19 50881820 50881821 NCIH2405_LUNG 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 NCIH2405_LUNG 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
PAX3 2 223158653 223158653 NCIH2405_LUNG 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAX5 9 37034095 37034095 NCIH2405_LUNG 37 5'UTR Del C - uc003zzo.1 PAX5_uc011lpw.1... Hybrid_Cap...
PDE4DIP p.Q1665fs 1 144873963 144873963 NCIH2405_LUNG 37 Frame_Shift_Del Del T - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDE4DIP p.V486fs 1 144917828 144917828 NCIH2405_LUNG 37 Frame_Shift_Del Del A - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PIK3C2G p.P129del 12 18435399 18435401 NCIH2405_LUNG 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PIP4K2C p.R210C 12 57992962 57992962 NCIH2405_LUNG 37 Missense_Mutation SNP C T uc001sou.2 PIP4K2C_uc001so... Hybrid_Cap... view
PRKACG p.R195C 9 71628426 71628426 NCIH2405_LUNG 37 Missense_Mutation SNP G A uc004agy.2 Hybrid_Cap... view
PRKD3 2 37480319 37480320 NCIH2405_LUNG 37 Stop_Codon_Ins Ins - T rs79875666 uc002rqd.2 Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 NCIH2405_LUNG 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PTGS2 1 186649449 186649449 NCIH2405_LUNG 37 5'UTR SNP G C uc001gsb.2 PTGS2_uc009wyo.... Hybrid_Cap... view
RGL2 p.L80W 6 33264810 33264810 NCIH2405_LUNG 37 Missense_Mutation SNP A C uc003odv.2 RGL2_uc003odu.2... Hybrid_Cap... view
TP63 3 189507518 189507519 NCIH2405_LUNG 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TRPS1 8 116635872 116635873 NCIH2405_LUNG 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TTBK1 p.E771del 6 43250726 43250728 NCIH2405_LUNG 37 In_Frame_Del Del GAA - uc003ouq.1 Hybrid_Cap...
VEGFC p.S419_splice 4 177605082 177605084 NCIH2405_LUNG 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
WDHD1 p.T657R 14 55448351 55448351 NCIH2405_LUNG 37 Missense_Mutation SNP G C uc001xbm.1 WDHD1_uc010aom.... Hybrid_Cap... view