Annotation Summary for Cell Line: NCI-H2444  

Cell line primary name: NCI-H2444
Cell line aliases: H2444
Gender: M
Site Primary: lung
Histology: carcinoma
Hist Subtype1: non_small_cell_carcinoma
Notes:
Source: ATCC
Expression arrays: PARES_p_NCLE_RNA_Redo_HG-U133_Plus_2_D12_257692
SNP arrays: ARLES_p_NCLE_DNAAffy2_S_GenomeWideSNP_6_F09_256138
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in NCI-H2444

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ADAM28 8 24211994 24211997 NCIH2444_LUNG 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 NCIH2444_LUNG 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ALPK1 4 113347609 113347610 NCIH2444_LUNG 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
ATRX p.N1705Y X 76888716 76888716 NCIH2444_LUNG 37 Missense_Mutation SNP T A uc004ecp.3 ATRX_uc004ecq.3... Hybrid_Cap... view
BCR 22 23631813 23631814 NCIH2444_LUNG 37 Intron Ins - C rs66503844 uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BLM p.K1186E 15 91346948 91346948 NCIH2444_LUNG 37 Missense_Mutation SNP A G uc002bpr.2 BLM_uc010uqh.1_... Hybrid_Cap... view
CACNB2 10 18828721 18828722 NCIH2444_LUNG 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CDK11B p.K127_splice 1 1647893 1647894 NCIH2444_LUNG 37 Splice_Site_Ins Ins - TTTCTT rs114930018 uc001agv.1 CDK11B_uc001ags... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 NCIH2444_LUNG 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN6 3 1339681 1339686 NCIH2444_LUNG 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
COL3A1 p.R485_splice 2 189859559 189859559 NCIH2444_LUNG 37 Splice_Site_SNP SNP T C uc002uqj.1 Hybrid_Cap... view
CREB3L2 p.T100del 7 137612914 137612916 NCIH2444_LUNG 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CYP1B1 2 38297654 38297655 NCIH2444_LUNG 37 3'UTR Ins - A rs9341258 uc002rqo.2 Hybrid_Cap...
CYP27B1 p.A372A 12 58158181 58158181 NCIH2444_LUNG 37 Silent SNP C G uc001spz.1 CYP27B1_uc001sq... Hybrid_Cap... view
DOCK3 p.L1783del 3 51411945 51411947 NCIH2444_LUNG 37 In_Frame_Del Del TGT - uc011bds.1 Hybrid_Cap...
DYRK1B 19 40320919 40320919 NCIH2444_LUNG 37 Intron SNP G A uc002omj.2 DYRK1B_uc002omi... Hybrid_Cap... view
EML4 2 42513256 42513256 NCIH2444_LUNG 37 Intron SNP A G uc002rsi.2 EML4_uc010fap.2... Hybrid_Cap... view
EPHA6 3 97367230 97367231 NCIH2444_LUNG 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
EPS15 1 51822189 51822189 NCIH2444_LUNG 37 3'UTR Del A - uc001csq.1 EPS15_uc009vyz.... Hybrid_Cap...
ETV1 7 14028708 14028708 NCIH2444_LUNG 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
ETV4 17 41607638 41607638 NCIH2444_LUNG 37 Intron SNP T G uc002idw.2 ETV4_uc002idv.2... Hybrid_Cap... view
FLI1 11 128638217 128638217 NCIH2444_LUNG 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLT4 5 180035187 180035187 NCIH2444_LUNG 37 Intron SNP G A uc003mlz.3 FLT4_uc003mma.3... Hybrid_Cap... view
GLI2 p.D97D 2 121708855 121708855 NCIH2444_LUNG 37 Silent SNP C T uc010flp.2 GLI2_uc010yyu.1... Hybrid_Cap... view
GPC3 X 132888208 132888208 NCIH2444_LUNG 37 Intron Del A - uc010nrn.1 GPC3_uc004exd.1... Hybrid_Cap...
GPR112 p.D2657del X 135474445 135474447 NCIH2444_LUNG 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 NCIH2444_LUNG 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 NCIH2444_LUNG 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HNF1A 12 121434630 121434631 NCIH2444_LUNG 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
HOXA11 7 27222362 27222362 NCIH2444_LUNG 37 3'UTR SNP G T uc003syx.2 HOXA10_uc003syw... Hybrid_Cap... view
HOXA11 7 27222389 27222389 NCIH2444_LUNG 37 3'UTR SNP C T uc003syx.2 HOXA10_uc003syw... Hybrid_Cap... view
ILK 11 6630029 6630029 NCIH2444_LUNG 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITGB1 10 33197131 33197134 NCIH2444_LUNG 37 Intron Del CTTT - rs116966876 uc001iwq.3 ITGB1_uc001iwp.... Hybrid_Cap...
KDR p.Q738* 4 55968118 55968118 NCIH2444_LUNG 37 Nonsense_Mutation SNP G A uc003has.2 KDR_uc003hat.1_... Hybrid_Cap... view
KRAS p.G12V 12 25398284 25398284 NCIH2444_LUNG 37 Missense_Mutation SNP C A uc001rgp.1 KRAS_uc001rgq.1... Hybrid_Cap... view
LRP2 p.D2253Y 2 170063473 170063473 NCIH2444_LUNG 37 Missense_Mutation SNP C A uc002ues.2 Hybrid_Cap... view
MAML2 p.604_607QQQQ>Q 11 95825375 95825383 NCIH2444_LUNG 37 In_Frame_Del Del TGCTG... - rs113349418 uc001pfw.1 Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 NCIH2444_LUNG 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 NCIH2444_LUNG 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 NCIH2444_LUNG 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MERTK p.A264G 2 112722801 112722801 NCIH2444_LUNG 37 Missense_Mutation SNP C G uc002thk.1 MERTK_uc002thl.... Hybrid_Cap... view
MLLT10 p.C178C 10 21903784 21903784 NCIH2444_LUNG 37 Silent SNP T C uc001iqs.2 MLLT10_uc001iqt... Hybrid_Cap... view
MYLK p.E1430_splice 3 123368043 123368044 NCIH2444_LUNG 37 Splice_Site_Ins Ins - G rs41431347 uc003ego.2 MYLK_uc010hrr.2... Hybrid_Cap...
MYST4 p.E1104del 10 76781906 76781908 NCIH2444_LUNG 37 In_Frame_Del Del GAA - rs79644703 uc001jwn.1 MYST4_uc001jwm.... Hybrid_Cap...
NACA p.S1236P 12 57111608 57111608 NCIH2444_LUNG 37 Missense_Mutation SNP A G rs12822307 uc009zoy.1 NACA_uc001slz.2... Hybrid_Cap... view
NCAM1 11 112832307 112832308 NCIH2444_LUNG 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 NCIH2444_LUNG 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA3 p.QQQ1272del 20 46279815 46279823 NCIH2444_LUNG 37 In_Frame_Del Del GCAGC... - uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NCOA3 20 46282414 46282414 NCIH2444_LUNG 37 3'UTR SNP A T uc002xtk.2 NCOA3_uc002xtl.... Hybrid_Cap... view
NEK3 p.K313_splice 13 52718050 52718051 NCIH2444_LUNG 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NFIA 1 61921185 61921186 NCIH2444_LUNG 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NPR1 1 153665919 153665920 NCIH2444_LUNG 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 NCIH2444_LUNG 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NUP214 9 134067556 134067557 NCIH2444_LUNG 37 Intron Ins - T rs66652901 uc004cag.2 NUP214_uc004cah... Hybrid_Cap...
OLFM4 p.F37L 13 53603082 53603082 NCIH2444_LUNG 37 Missense_Mutation SNP C A uc001vhl.2 OLFM4_uc001vhk.... Hybrid_Cap... view
PDE4DIP p.L601fs 1 144915624 144915624 NCIH2444_LUNG 37 Frame_Shift_Del Del G - rs1778112 uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDE4DIP p.E243fs 1 144923729 144923729 NCIH2444_LUNG 37 Frame_Shift_Del Del T - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDGFB 22 39636899 39636900 NCIH2444_LUNG 37 Intron Ins - TCTC rs72014707 uc003axf.2 PDGFB_uc003axe.... Hybrid_Cap...
PRDM16 p.D742Y 1 3328985 3328985 NCIH2444_LUNG 37 Missense_Mutation SNP G T uc001akf.2 PRDM16_uc001akc... Hybrid_Cap... view
PREX2 8 69143775 69143775 NCIH2444_LUNG 37 3'UTR SNP T C uc003xxv.1 Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 NCIH2444_LUNG 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PRKG2 p.I314N 4 82074847 82074847 NCIH2444_LUNG 37 Missense_Mutation SNP A T uc003hmh.2 PRKG2_uc011ccf.... Hybrid_Cap... view
PTEN p.P96S 10 89692802 89692802 NCIH2444_LUNG 37 Missense_Mutation SNP C T uc001kfb.2 Hybrid_Cap... view
PTPRC p.H555P 1 198691555 198691555 NCIH2444_LUNG 37 Missense_Mutation SNP A C uc001gur.1 PTPRC_uc001gus.... Hybrid_Cap... view
RECQL4 p.R766fs 8 145738768 145738768 NCIH2444_LUNG 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
ROBO1 p.E1034* 3 78685196 78685196 NCIH2444_LUNG 37 Nonsense_Mutation SNP C A uc003dqe.2 ROBO1_uc003dqb.... Hybrid_Cap... view
RPS6KL1 14 75373626 75373627 NCIH2444_LUNG 37 3'UTR Ins - TGAT uc001xqx.1 RPS6KL1_uc001xq... Hybrid_Cap...
STK31 7 23872024 23872025 NCIH2444_LUNG 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TEC 4 48139307 48139310 NCIH2444_LUNG 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TIAM1 p.G438C 21 32624157 32624157 NCIH2444_LUNG 37 Missense_Mutation SNP C A uc002yow.1 TIAM1_uc011adk.... Hybrid_Cap... view
TMEM123 11 102269398 102269398 NCIH2444_LUNG 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TP53 p.Y236C 17 7577574 7577574 NCIH2444_LUNG 37 Missense_Mutation SNP T C uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TP63 3 189507518 189507519 NCIH2444_LUNG 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TRIM33 1 114940215 114940216 NCIH2444_LUNG 37 3'UTR Ins - G rs68133208 uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TRIM33 p.Q1046E 1 114940597 114940597 NCIH2444_LUNG 37 Missense_Mutation SNP G C uc001eew.2 TRIM33_uc010owr... Hybrid_Cap... view
TRPS1 8 116635872 116635873 NCIH2444_LUNG 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TTN p.P4796Q 2 179595007 179595008 NCIH2444_LUNG 37 Missense_Mutation DNP GG TT uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.A3045T 2 179633430 179633430 NCIH2444_LUNG 37 Missense_Mutation SNP C T rs36059692 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 NCIH2444_LUNG 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...