Annotation Summary for Cell Line: NCI-H2452  

Cell line primary name: NCI-H2452
Cell line aliases: H2452
Gender: M
Site Primary: pleura
Histology: mesothelioma
Hist Subtype1: NS
Notes:
Source: ATCC
Expression arrays: MAKER_p_NCLE_RNA7_HG-U133_Plus_2_C08_454624
SNP arrays: PODIA_p_NCLE_DNAAffy7_GenomeWideSNP_6_B02_437542
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in NCI-H2452

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 NCIH2452_PLEURA 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ACACA 17 35766564 35766564 NCIH2452_PLEURA 37 5'UTR Del A - uc002hno.2 ACACA_uc002hnn.... Hybrid_Cap...
ADAM17 2 9630245 9630245 NCIH2452_PLEURA 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 NCIH2452_PLEURA 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 NCIH2452_PLEURA 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ALPK1 4 113347609 113347610 NCIH2452_PLEURA 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 NCIH2452_PLEURA 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
BAP1 p.A95D 3 52442065 52442065 NCIH2452_PLEURA 37 Missense_Mutation SNP G T uc003ddx.2 PHF7_uc003ddy.2... Hybrid_Cap... view
BUB1B p.E409D 15 40488914 40488914 NCIH2452_PLEURA 37 Missense_Mutation SNP A C rs28989188 uc001zkx.3 BUB1B_uc010ucl.... Hybrid_Cap... view
CACNB2 10 18828721 18828722 NCIH2452_PLEURA 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CAMK2A 5 149602223 149602224 NCIH2452_PLEURA 37 3'UTR Del AC - uc003lrt.2 CAMK2A_uc003lrs... Hybrid_Cap...
CDC42BPA p.D1674N 1 227182532 227182532 NCIH2452_PLEURA 37 Missense_Mutation SNP C T uc001hqr.2 CDC42BPA_uc001h... Hybrid_Cap... view
CDK11B 1 1654066 1654068 NCIH2452_PLEURA 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 NCIH2452_PLEURA 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CREB3L2 p.T100del 7 137612914 137612916 NCIH2452_PLEURA 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CYLD 16 50783545 50783545 NCIH2452_PLEURA 37 5'UTR SNP G A uc002egp.1 CYLD_uc002egn.1... Hybrid_Cap... view
DYRK1A 21 38884966 38884967 NCIH2452_PLEURA 37 3'UTR Ins - T rs72430212 uc002ywk.2 DYRK1A_uc002ywi... Hybrid_Cap...
EP300 22 41574970 41574972 NCIH2452_PLEURA 37 3'UTR Del GTA - rs76489032 uc003azl.3 Hybrid_Cap...
EPHA6 3 97367230 97367231 NCIH2452_PLEURA 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
ETV1 7 14028708 14028708 NCIH2452_PLEURA 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FGFR1OP 6 167453519 167453520 NCIH2452_PLEURA 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 NCIH2452_PLEURA 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLI1 11 128638217 128638217 NCIH2452_PLEURA 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FMN2 p.PPLPGAGIPPP939del 1 240370914 240370946 NCIH2452_PLEURA 37 In_Frame_Del Del GCCCC... - rs4997328;rs4997329 uc010pye.1 FMN2_uc010pyd.1... Hybrid_Cap...
FN1 2 216244182 216244185 NCIH2452_PLEURA 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GPR112 p.D2657del X 135474445 135474447 NCIH2452_PLEURA 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 NCIH2452_PLEURA 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
HNF1A 12 121434630 121434631 NCIH2452_PLEURA 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
ILK 11 6630029 6630029 NCIH2452_PLEURA 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ISG15 1 948846 948847 NCIH2452_PLEURA 37 5'UTR Ins - A rs33916361 uc001acj.3 Hybrid_Cap...
ITPR2 12 26639765 26639765 NCIH2452_PLEURA 37 Intron SNP G T uc001rhg.2 ITPR2_uc009zjg.... Hybrid_Cap... view
ITPR2 p.R470_splice 12 26834804 26834805 NCIH2452_PLEURA 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
MAML2 p.604_607QQQQ>Q 11 95825375 95825383 NCIH2452_PLEURA 37 In_Frame_Del Del TGCTG... - rs113349418 uc001pfw.1 Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 NCIH2452_PLEURA 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 NCIH2452_PLEURA 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAPKAPK3 3 50685575 50685575 NCIH2452_PLEURA 37 3'UTR Del A - rs76026164 uc003day.1 MAPKAPK3_uc003d... Hybrid_Cap...
MSH3 p.PPA66del 5 79950742 79950750 NCIH2452_PLEURA 37 In_Frame_Del Del CCCCC... - rs60484572;rs1047489 uc003kgz.2 DHFR_uc011ctl.1... Hybrid_Cap...
MYO18B p.R441H 22 26165205 26165205 NCIH2452_PLEURA 37 Missense_Mutation SNP G A uc003abz.1 MYO18B_uc003aca... Hybrid_Cap... view
MYST4 10 76790936 76790936 NCIH2452_PLEURA 37 3'UTR Del A - uc001jwn.1 MYST4_uc001jwo.... Hybrid_Cap...
NCAM1 11 112832307 112832308 NCIH2452_PLEURA 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 NCIH2452_PLEURA 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA3 p.T184T 20 46256324 46256324 NCIH2452_PLEURA 37 Silent SNP A G uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap... view
NCOA3 20 46282339 46282340 NCIH2452_PLEURA 37 3'UTR Ins - AT uc002xtk.2 NCOA3_uc002xtl.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 NCIH2452_PLEURA 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NPR1 1 153665919 153665920 NCIH2452_PLEURA 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 NCIH2452_PLEURA 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NR3C1 5 142780419 142780419 NCIH2452_PLEURA 37 Splice_Site_SNP SNP T A uc003lmy.2 NR3C1_uc003lmz.... Hybrid_Cap... view
PAX3 2 223158653 223158653 NCIH2452_PLEURA 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PDE4DIP p.S2089del 1 144859817 144859819 NCIH2452_PLEURA 37 In_Frame_Del Del GGA - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDK4 7 95221928 95221928 NCIH2452_PLEURA 37 Intron Del A - uc003uoa.2 PDK4_uc003unz.2... Hybrid_Cap...
PIK3C2G p.P129del 12 18435399 18435401 NCIH2452_PLEURA 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PMS2 p.Q237Q 7 6037049 6037049 NCIH2452_PLEURA 37 Silent SNP T C uc003spl.2 PMS2_uc003spj.2... Hybrid_Cap... view
PRKCA 17 64298959 64298960 NCIH2452_PLEURA 37 5'UTR Ins - G rs71160558 uc002jfp.1 PRKCA_uc002jfo.... Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 NCIH2452_PLEURA 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PTPN1 20 49126994 49126994 NCIH2452_PLEURA 37 5'UTR SNP C T uc002xvl.2 PTPN1_uc010zys.... Hybrid_Cap... view
PXDN p.P864R 2 1652961 1652961 NCIH2452_PLEURA 37 Missense_Mutation SNP G C uc002qxa.2 Hybrid_Cap... view
RBL2 p.A62fs 16 53468653 53468654 NCIH2452_PLEURA 37 Frame_Shift_Ins Ins - G uc002ehi.3 RBL2_uc010vgv.1... Hybrid_Cap...
RPS6KB1 17 58024224 58024225 NCIH2452_PLEURA 37 3'UTR Ins - AA rs67846207 uc002ixy.2 RPS6KB1_uc010dd... Hybrid_Cap...
RPS6KL1 14 75373626 75373627 NCIH2452_PLEURA 37 3'UTR Ins - TGAT uc001xqx.1 RPS6KL1_uc001xq... Hybrid_Cap...
SIK1 p.G17D 21 44846009 44846009 NCIH2452_PLEURA 37 Missense_Mutation SNP C T uc002zdf.2 Hybrid_Cap... view
STK31 7 23872024 23872025 NCIH2452_PLEURA 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TEC 4 48139307 48139310 NCIH2452_PLEURA 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TMEM123 11 102269461 102269461 NCIH2452_PLEURA 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TRIM33 1 114940212 114940212 NCIH2452_PLEURA 37 3'UTR Del T - uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TSC2 16 2138671 2138672 NCIH2452_PLEURA 37 3'UTR Del AA - uc002con.2 TSC2_uc010bsd.2... Hybrid_Cap...
TTBK1 p.E771del 6 43250726 43250728 NCIH2452_PLEURA 37 In_Frame_Del Del GAA - uc003ouq.1 Hybrid_Cap...
TTN p.D16390N 2 179463565 179463565 NCIH2452_PLEURA 37 Missense_Mutation SNP C T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFA p.M300V 6 43746239 43746239 NCIH2452_PLEURA 37 Missense_Mutation SNP A G uc003owh.2 VEGFA_uc003owc.... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 NCIH2452_PLEURA 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
WNK4 17 40945874 40945875 NCIH2452_PLEURA 37 Intron Ins - T uc002ibj.2 WNK4_uc010wgx.1... Hybrid_Cap...
ZMYM2 p.V483fs 13 20580662 20580662 NCIH2452_PLEURA 37 Frame_Shift_Del Del T - uc001umr.2 ZMYM2_uc001umq.... Hybrid_Cap...