Annotation Summary for Cell Line: NCI-H526  

Cell line primary name: NCI-H526
Cell line aliases: H526
Gender: M
Site Primary: lung
Histology: carcinoma
Hist Subtype1: small_cell_carcinoma
Notes:
Source: ATCC
Expression arrays: PARES_p_NCLE_RNA_Redo_HG-U133_Plus_2_A05_257606
SNP arrays: HONEY_p_NCLE_DNAAffy3_S_GenomeWideSNP_6_G09_293440
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in NCI-H526

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 NCIH526_LUNG 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ADAM17 2 9630245 9630245 NCIH526_LUNG 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 NCIH526_LUNG 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADAMTS20 p.V1330F 12 43821230 43821230 NCIH526_LUNG 37 Missense_Mutation SNP C A uc010skx.1 ADAMTS20_uc001r... Hybrid_Cap... view
ADARB2 p.A493S 10 1279672 1279672 NCIH526_LUNG 37 Missense_Mutation SNP C A uc009xhq.2 Hybrid_Cap... view
AGAP2 12 58135867 58135867 NCIH526_LUNG 37 5'UTR SNP T A uc001spr.2 TSPAN31_uc001sp... Hybrid_Cap... view
AIFM3 p.P58R 22 21327737 21327737 NCIH526_LUNG 37 Missense_Mutation SNP C G uc002ztj.2 AIFM3_uc002ztk.... Hybrid_Cap... view
AIM1 p.D1620fs 6 107009321 107009322 NCIH526_LUNG 37 Frame_Shift_Ins Ins - G uc003prh.2 AIM1_uc003pri.2... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 NCIH526_LUNG 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP6 p.S585F 14 33015613 33015613 NCIH526_LUNG 37 Missense_Mutation SNP C T uc001wrq.2 AKAP6_uc010aml.... Hybrid_Cap... view
AKAP9 p.L512P 7 91630766 91630766 NCIH526_LUNG 37 Missense_Mutation SNP T C uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap... view
AKAP9 p.1335_1336insQ 7 91652178 91652179 NCIH526_LUNG 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 NCIH526_LUNG 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ALPK2 p.P10L 18 56279001 56279001 NCIH526_LUNG 37 Missense_Mutation SNP G A uc002lhj.3 Hybrid_Cap... view
ALPK3 p.G1027V 15 85400443 85400443 NCIH526_LUNG 37 Missense_Mutation SNP G T uc002ble.2 Hybrid_Cap... view
AR p.A588S X 66863243 66863243 NCIH526_LUNG 37 Missense_Mutation SNP G T uc004dwu.1 AR_uc011mpd.1_M... Hybrid_Cap... view
ATRX p.S1944N X 76855005 76855005 NCIH526_LUNG 37 Missense_Mutation SNP C T uc004ecp.3 ATRX_uc004ecq.3... Hybrid_Cap... view
CDK11B p.K127_splice 1 1647893 1647894 NCIH526_LUNG 37 Splice_Site_Ins Ins - TTTCTT rs114930018 uc001agv.1 CDK11B_uc001ags... Hybrid_Cap...
CDKL4 p.G97_splice 2 39452979 39452979 NCIH526_LUNG 37 Splice_Site_SNP SNP C T uc010fal.1 CDKL4_uc002rrm.... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 NCIH526_LUNG 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN6 3 1339681 1339686 NCIH526_LUNG 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
CSMD3 p.M1444I 8 113564852 113564852 NCIH526_LUNG 37 Missense_Mutation SNP C T uc003ynu.2 CSMD3_uc003yns.... Hybrid_Cap... view
CYP27B1 12 58156782 58156782 NCIH526_LUNG 37 3'UTR SNP C T uc001spz.1 CYP27B1_uc001sq... Hybrid_Cap... view
DDR1 p.V454M 6 30862295 30862295 NCIH526_LUNG 37 Missense_Mutation SNP G A uc003nrv.2 DDR1_uc010jse.2... Hybrid_Cap... view
DST 6 56481367 56481367 NCIH526_LUNG 37 Intron SNP C A uc003pdf.2 DST_uc003pcz.3_... Hybrid_Cap... view
EPHA3 p.E471D 3 89445093 89445093 NCIH526_LUNG 37 Missense_Mutation SNP G C uc003dqy.2 EPHA3_uc003dqx.... Hybrid_Cap... view
EPHA5 4 66189753 66189754 NCIH526_LUNG 37 3'UTR Ins - T rs67487372 uc011cah.1 EPHA5_uc003hcx.... Hybrid_Cap...
EPHA5 p.L500V 4 66286188 66286188 NCIH526_LUNG 37 Missense_Mutation SNP G C uc011cah.1 EPHA5_uc003hcx.... Hybrid_Cap... view
ERBB3 12 56492422 56492423 NCIH526_LUNG 37 Intron Ins - C uc001sjh.2 ERBB3_uc009zoj.... Hybrid_Cap...
ERBB4 2 212248321 212248321 NCIH526_LUNG 37 3'UTR SNP T A uc002veg.1 ERBB4_uc002veh.... Hybrid_Cap... view
ETV1 p.A61A 7 14017104 14017104 NCIH526_LUNG 37 Silent SNP A T uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap... view
ETV1 7 14028708 14028708 NCIH526_LUNG 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FGFR1OP 6 167453519 167453520 NCIH526_LUNG 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FLI1 11 128638217 128638217 NCIH526_LUNG 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLT4 5 180035153 180035153 NCIH526_LUNG 37 Intron SNP G A uc003mlz.3 FLT4_uc003mma.3... Hybrid_Cap... view
GHR p.T158N 5 42699959 42699959 NCIH526_LUNG 37 Missense_Mutation SNP C A uc003jmt.2 GHR_uc011cpq.1_... Hybrid_Cap... view
GLTSCR1 p.D905N 19 48197801 48197801 NCIH526_LUNG 37 Missense_Mutation SNP G A uc002phh.3 GLTSCR1_uc002ph... Hybrid_Cap... view
GNAS p.K602M 20 57430125 57430125 NCIH526_LUNG 37 Missense_Mutation SNP A T uc002xzw.2 GNAS_uc002xzt.2... Hybrid_Cap... view
GPR112 p.D2657del X 135474445 135474447 NCIH526_LUNG 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GPR141 p.C258F 7 37780768 37780768 NCIH526_LUNG 37 Missense_Mutation SNP G T uc003tfm.1 Hybrid_Cap... view
GRIA3 X 122318386 122318387 NCIH526_LUNG 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 NCIH526_LUNG 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HDAC2 p.S81del 6 114292110 114292112 NCIH526_LUNG 37 In_Frame_Del Del CTG - uc003pwd.1 HDAC2_uc003pwc.... Hybrid_Cap...
HEPH X 65486575 65486575 NCIH526_LUNG 37 3'UTR SNP G T uc011moz.1 HEPH_uc004dwn.2... Hybrid_Cap... view
HIF1A 14 62213929 62213930 NCIH526_LUNG 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
ILK 11 6630029 6630029 NCIH526_LUNG 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITPR1 p.N2212D 3 4829793 4829793 NCIH526_LUNG 37 Missense_Mutation SNP A G uc003bqa.2 ITPR1_uc010hca.... Hybrid_Cap... view
ITPR1 3 4836715 4836715 NCIH526_LUNG 37 Intron SNP C G uc003bqa.2 ITPR1_uc010hca.... Hybrid_Cap... view
ITPR1 p.F2332V 3 4847817 4847817 NCIH526_LUNG 37 Missense_Mutation SNP T G uc003bqa.2 ITPR1_uc010hca.... Hybrid_Cap... view
ITPR2 12 26639765 26639765 NCIH526_LUNG 37 Intron SNP G T uc001rhg.2 ITPR2_uc009zjg.... Hybrid_Cap... view
LAMA1 p.N328N 18 7043397 7043397 NCIH526_LUNG 37 Silent SNP A G uc002knm.2 LAMA1_uc010wzj.... Hybrid_Cap... view
LRP6 p.G542D 12 12318150 12318150 NCIH526_LUNG 37 Missense_Mutation SNP C T uc001rah.3 BCL2L14_uc001ra... Hybrid_Cap... view
MAML2 p.604_607QQQQ>Q 11 95825375 95825383 NCIH526_LUNG 37 In_Frame_Del Del TGCTG... - rs113349418 uc001pfw.1 Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 NCIH526_LUNG 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 NCIH526_LUNG 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAPKAPK3 3 50685575 50685575 NCIH526_LUNG 37 3'UTR Del A - rs76026164 uc003day.1 MAPKAPK3_uc003d... Hybrid_Cap...
MARK1 p.A185_splice 1 220791651 220791651 NCIH526_LUNG 37 Splice_Site_SNP SNP G T uc009xdw.2 MARK1_uc001hmn.... Hybrid_Cap... view
MLL3 p.Y816fs 7 151945071 151945072 NCIH526_LUNG 37 Frame_Shift_Ins Ins - T uc003wla.2 Hybrid_Cap...
MYH1 p.D169_splice 17 10418213 10418213 NCIH526_LUNG 37 Splice_Site_SNP SNP C G uc002gmo.2 Hybrid_Cap... view
MYO18B p.G2295C 22 26422823 26422823 NCIH526_LUNG 37 Missense_Mutation SNP G T uc003abz.1 MYO18B_uc003aca... Hybrid_Cap... view
NACA p.V371M 12 57114203 57114203 NCIH526_LUNG 37 Missense_Mutation SNP C T uc009zoy.1 NACA_uc001slz.2... Hybrid_Cap... view
NAV3 p.C479F 12 78400754 78400754 NCIH526_LUNG 37 Missense_Mutation SNP G T uc001syp.2 NAV3_uc001syo.2... Hybrid_Cap... view
NCAM1 11 112832307 112832308 NCIH526_LUNG 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 NCIH526_LUNG 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 NCIH526_LUNG 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NFATC1 18 77287653 77287654 NCIH526_LUNG 37 3'UTR Del AA - uc010xfg.1 NFATC1_uc002lnd... Hybrid_Cap...
NFIA 1 61921185 61921186 NCIH526_LUNG 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NOVA1 p.T392I 14 26917514 26917514 NCIH526_LUNG 37 Missense_Mutation SNP G A uc001wpy.2 NOVA1_uc001wpz.... Hybrid_Cap... view
NPR1 1 153665919 153665920 NCIH526_LUNG 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 NCIH526_LUNG 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NUP133 p.L976F 1 229593960 229593960 NCIH526_LUNG 37 Missense_Mutation SNP C G uc001htn.2 Hybrid_Cap... view
NUP214 9 134067556 134067557 NCIH526_LUNG 37 Intron Ins - T rs66652901 uc004cag.2 NUP214_uc004cah... Hybrid_Cap...
PAK3 p.P14L X 110366372 110366372 NCIH526_LUNG 37 Missense_Mutation SNP C T uc010npv.1 PAK3_uc010npt.1... Hybrid_Cap... view
PDE4DIP p.A2053G 1 144859926 144859926 NCIH526_LUNG 37 Missense_Mutation SNP G C uc001elw.3 NBPF10_uc009wir... Hybrid_Cap... view
PDE4DIP p.Q1665fs 1 144873963 144873963 NCIH526_LUNG 37 Frame_Shift_Del Del T - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDE4DIP p.V486fs 1 144917828 144917828 NCIH526_LUNG 37 Frame_Shift_Del Del A - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDGFA 7 538108 538108 NCIH526_LUNG 37 3'UTR SNP C T uc003sir.2 PDGFA_uc003sis.... Hybrid_Cap... view
PGR 11 100933598 100933599 NCIH526_LUNG 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PIK3C2G p.K1455N 12 18800866 18800866 NCIH526_LUNG 37 Missense_Mutation SNP G T uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap... view
PIK3CG p.P563T 7 106509693 106509693 NCIH526_LUNG 37 Missense_Mutation SNP C A uc003vdv.3 PIK3CG_uc003vdu... Hybrid_Cap... view
PPARGC1A p.Q454* 4 23815746 23815746 NCIH526_LUNG 37 Nonsense_Mutation SNP G A uc003gqs.2 PPARGC1A_uc003g... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 NCIH526_LUNG 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
RAD21 p.K479N 8 117864220 117864220 NCIH526_LUNG 37 Missense_Mutation SNP T A uc003yod.2 Hybrid_Cap... view
RECQL4 p.R766fs 8 145738768 145738768 NCIH526_LUNG 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
ROS1 p.P2130T 6 117631290 117631290 NCIH526_LUNG 37 Missense_Mutation SNP G T uc003pxp.1 ROS1_uc011ebi.1... Hybrid_Cap... view
SACS p.E1254* 13 23914255 23914255 NCIH526_LUNG 37 Nonsense_Mutation SNP C A uc001uon.2 SACS_uc001uoo.2... Hybrid_Cap... view
STK31 7 23872024 23872025 NCIH526_LUNG 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TMEM123 11 102269398 102269398 NCIH526_LUNG 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TNNI3K p.N804D 1 74929220 74929220 NCIH526_LUNG 37 Missense_Mutation SNP A G uc001dge.1 TNNI3K_uc001dgd... Hybrid_Cap... view
TNRC6B p.Q1328del 22 40697177 40697179 NCIH526_LUNG 37 In_Frame_Del Del GCA - rs114291931 uc011aor.1 TNRC6B_uc003aym... Hybrid_Cap...
TOP1 p.L325_splice 20 39726978 39726978 NCIH526_LUNG 37 Splice_Site_SNP SNP G A uc002xjl.2 Hybrid_Cap... view
TP53 p.S33_splice 17 7579591 7579591 NCIH526_LUNG 37 Splice_Site_SNP SNP C G uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TP53BP1 15 43699471 43699471 NCIH526_LUNG 37 3'UTR SNP A G uc001zrr.3 TP53BP1_uc010ud... Hybrid_Cap... view
TP53BP1 p.K1499T 15 43712688 43712688 NCIH526_LUNG 37 Missense_Mutation SNP T G uc001zrr.3 TP53BP1_uc010ud... Hybrid_Cap... view
TP63 3 189507518 189507519 NCIH526_LUNG 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TRIO p.E2227D 5 14485201 14485201 NCIH526_LUNG 37 Missense_Mutation SNP A C uc003jff.2 TRIO_uc003jfg.2... Hybrid_Cap... view
TRPS1 8 116635872 116635873 NCIH526_LUNG 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TTK 6 80752005 80752005 NCIH526_LUNG 37 3'UTR SNP A C uc003pjc.2 TTK_uc003pjb.3_... Hybrid_Cap... view
TTN p.C12661R 2 179485652 179485652 NCIH526_LUNG 37 Missense_Mutation SNP A G uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TXK p.L355F 4 48082039 48082039 NCIH526_LUNG 37 Missense_Mutation SNP G A uc003gxx.3 TXK_uc010igj.2_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 NCIH526_LUNG 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
VPS13B p.S1263F 8 100493948 100493948 NCIH526_LUNG 37 Missense_Mutation SNP C T uc003yiv.2 VPS13B_uc003yiw... Hybrid_Cap... view
WHSC1L1 p.E352G 8 38188959 38188959 NCIH526_LUNG 37 Missense_Mutation SNP T C uc003xli.2 WHSC1L1_uc011lb... Hybrid_Cap... view
WLS 1 68592001 68592001 NCIH526_LUNG 37 Intron SNP T C uc001dee.2 WLS_uc001def.1_... Hybrid_Cap... view
YSK4 p.Q921* 2 135743681 135743681 NCIH526_LUNG 37 Nonsense_Mutation SNP G A uc002tue.1 YSK4_uc002tuf.1... Hybrid_Cap... view