Annotation Summary for Cell Line: NCI-H647  

Cell line primary name: NCI-H647
Cell line aliases: H647
Gender: M
Site Primary: lung
Histology: carcinoma
Hist Subtype1: mixed_adenosquamous_carcinoma
Notes:
Source: ATCC
Expression arrays: NIECE_p_NCLE_RNA3_HG-U133_Plus_2_A10_296008
SNP arrays: ARLES_p_NCLE_DNAAffy2_S_GenomeWideSNP_6_G04_256152
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in NCI-H647

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ADAM28 8 24211994 24211997 NCIH647_LUNG 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 NCIH647_LUNG 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP9 p.K395Q 7 91630414 91630414 NCIH647_LUNG 37 Missense_Mutation SNP A C uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap... view
AURKC 19 57742494 57742507 NCIH647_LUNG 37 5'UTR Del GGACG... - rs67926438;rs112039303;rs59094959 uc002qoe.2 AURKC_uc002qoc.... Hybrid_Cap...
BCL3 19 45262965 45262968 NCIH647_LUNG 37 3'UTR Del CCCC - uc010xxe.1 Hybrid_Cap...
BCR 22 23631813 23631814 NCIH647_LUNG 37 Intron Ins - C rs66503844 uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BCR 22 23632777 23632778 NCIH647_LUNG 37 Intron Ins - T uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
C15ORF2 p.A278S 15 24921846 24921846 NCIH647_LUNG 37 Missense_Mutation SNP G T uc001ywo.2 Hybrid_Cap... view
CACNB2 10 18828721 18828722 NCIH647_LUNG 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CDK11B 1 1654066 1654068 NCIH647_LUNG 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 NCIH647_LUNG 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN6 3 1339681 1339686 NCIH647_LUNG 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
DACH1 13 72014625 72014626 NCIH647_LUNG 37 3'UTR Ins - T rs117109529 uc010thn.1 DACH1_uc010tho.... Hybrid_Cap...
DAPK2 p.A237V 15 64218242 64218242 NCIH647_LUNG 37 Missense_Mutation SNP G A uc002amr.2 DAPK2_uc010uim.... Hybrid_Cap... view
DNAH8 6 38952247 38952250 NCIH647_LUNG 37 Intron Del CACA - uc003ooe.1 DNAH8_uc003oog.... Hybrid_Cap...
E2F1 p.T207I 20 32266112 32266112 NCIH647_LUNG 37 Missense_Mutation SNP G A uc002wzu.3 Hybrid_Cap... view
EIF3A p.E592* 10 120817671 120817671 NCIH647_LUNG 37 Nonsense_Mutation SNP C A uc001ldu.2 EIF3A_uc010qsu.... Hybrid_Cap... view
EIF4E 4 99808137 99808141 NCIH647_LUNG 37 Intron Del TTAAA - uc011ceb.1 EIF4E_uc011cea.... Hybrid_Cap...
EP300 22 41574970 41574972 NCIH647_LUNG 37 3'UTR Del GTA - rs76489032 uc003azl.3 Hybrid_Cap...
EPHA6 3 97367230 97367231 NCIH647_LUNG 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
FANCE 6 35434338 35434338 NCIH647_LUNG 37 3'UTR Del C - rs79295372 uc003oko.1 FANCE_uc010jvw.... Hybrid_Cap...
FGFR1OP 6 167453519 167453520 NCIH647_LUNG 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR2 p.S454L 10 123263385 123263385 NCIH647_LUNG 37 Missense_Mutation SNP G A uc010qtj.1 FGFR2_uc010qtg.... Hybrid_Cap... view
FGFR3 4 1809128 1809129 NCIH647_LUNG 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLI1 11 128638217 128638217 NCIH647_LUNG 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FN1 2 216244182 216244185 NCIH647_LUNG 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GPR112 p.D2657del X 135474445 135474447 NCIH647_LUNG 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRB7 p.P269L 17 37900810 37900810 NCIH647_LUNG 37 Missense_Mutation SNP C T uc002hsr.2 GRB7_uc002hss.2... Hybrid_Cap... view
GRIA3 X 122318386 122318387 NCIH647_LUNG 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 NCIH647_LUNG 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HIF1A 14 62213929 62213930 NCIH647_LUNG 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HNF1A 12 121434630 121434631 NCIH647_LUNG 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
ILK 11 6630029 6630029 NCIH647_LUNG 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 NCIH647_LUNG 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
JARID2 p.H740Y 6 15501410 15501410 NCIH647_LUNG 37 Missense_Mutation SNP C T uc003nbj.2 JARID2_uc011div... Hybrid_Cap... view
KCNH2 p.A307T 7 150654588 150654588 NCIH647_LUNG 37 Missense_Mutation SNP C T uc003wic.2 KCNH2_uc003wib.... Hybrid_Cap... view
KLK7 19 51480672 51480675 NCIH647_LUNG 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
KRAS p.G13D 12 25398281 25398281 NCIH647_LUNG 37 Missense_Mutation SNP C T rs112445441 uc001rgp.1 KRAS_uc001rgq.1... Hybrid_Cap... view
LMNA p.R527H 1 156106995 156106995 NCIH647_LUNG 37 Missense_Mutation SNP G A rs57520892 uc001fni.2 LMNA_uc001fnf.1... Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 NCIH647_LUNG 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP2K1 15 66679649 66679650 NCIH647_LUNG 37 5'UTR Ins - C rs67229745 uc010bhq.2 Hybrid_Cap...
MAP2K3 p.F275S 17 21215503 21215503 NCIH647_LUNG 37 Missense_Mutation SNP T C uc002gys.2 MAP2K3_uc002gyt... Hybrid_Cap... view
MAP3K1 p.T949del 5 56177849 56177851 NCIH647_LUNG 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 NCIH647_LUNG 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAP3K4 p.A1199del 6 161519351 161519353 NCIH647_LUNG 37 In_Frame_Del Del CTG - uc003qtn.2 MAP3K4_uc010kkc... Hybrid_Cap...
MCM3APAS 21 47671275 47671276 NCIH647_LUNG 37 3'UTR Ins - AAT rs67797185 uc002zin.2 MCM3APAS_uc002z... Hybrid_Cap...
MYCN 2 16082178 16082178 NCIH647_LUNG 37 5'UTR SNP G A uc002rci.2 MYCNOS_uc002rch... Hybrid_Cap... view
NAV3 p.L2128del 12 78591116 78591118 NCIH647_LUNG 37 In_Frame_Del Del TCT - uc001syp.2 NAV3_uc001syo.2... Hybrid_Cap...
NCAM1 11 112832307 112832308 NCIH647_LUNG 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 NCIH647_LUNG 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA3 p.Q1276del 20 46279837 46279839 NCIH647_LUNG 37 In_Frame_Del Del CAG - rs2664555 uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 NCIH647_LUNG 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NEK7 1 198288832 198288832 NCIH647_LUNG 37 3'UTR SNP C T uc001gun.3 Hybrid_Cap... view
NFATC1 18 77287653 77287654 NCIH647_LUNG 37 3'UTR Del AA - uc010xfg.1 NFATC1_uc002lnd... Hybrid_Cap...
NIN 14 51194310 51194314 NCIH647_LUNG 37 Intron Del TATCT - uc001wyi.2 NIN_uc001wyj.2_... Hybrid_Cap...
NOTCH4 p.15_16LL>L 6 32191659 32191661 NCIH647_LUNG 37 In_Frame_Del Del AGC - uc003obb.2 NOTCH4_uc011dpu... Hybrid_Cap...
NPM1 5 170837734 170837734 NCIH647_LUNG 37 3'UTR Del T - uc011dex.1 NPM1_uc003mbi.2... Hybrid_Cap...
NPR1 1 153665919 153665920 NCIH647_LUNG 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 NCIH647_LUNG 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NUP214 9 134067556 134067557 NCIH647_LUNG 37 Intron Ins - T rs66652901 uc004cag.2 NUP214_uc004cah... Hybrid_Cap...
PAX3 2 223066593 223066593 NCIH647_LUNG 37 Intron SNP C T uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap... view
PAX3 2 223158653 223158653 NCIH647_LUNG 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PCM1 8 17813218 17813218 NCIH647_LUNG 37 Intron Del T - uc003wyi.3 PCM1_uc011kyh.1... Hybrid_Cap...
PGGT1B 5 114548071 114548072 NCIH647_LUNG 37 3'UTR Ins - C uc003kqw.3 PGGT1B_uc003kqx... Hybrid_Cap...
PGR 11 100933598 100933599 NCIH647_LUNG 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PKN2 p.L384del 1 89250482 89250484 NCIH647_LUNG 37 In_Frame_Del Del TCT - uc001dmn.2 PKN2_uc001dmm.1... Hybrid_Cap...
PRKACB 1 84670439 84670440 NCIH647_LUNG 37 Intron Ins - C rs67519258 uc001djl.2 PRKACB_uc001djj... Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 NCIH647_LUNG 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PXN p.V501M 12 120651653 120651653 NCIH647_LUNG 37 Missense_Mutation SNP C T uc001txt.2 PXN_uc001txu.2_... Hybrid_Cap... view
RANBP17 p.K826N 5 170667987 170667987 NCIH647_LUNG 37 Missense_Mutation SNP A C uc003mba.2 RANBP17_uc003mb... Hybrid_Cap... view
RAPGEF2 4 160189200 160189201 NCIH647_LUNG 37 5'UTR Ins - T rs72011511 uc003iqg.3 Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 NCIH647_LUNG 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
ROBO1 p.A1575G 3 78655903 78655903 NCIH647_LUNG 37 Missense_Mutation SNP G C uc003dqe.2 ROBO1_uc003dqb.... Hybrid_Cap... view
STK19 p.G278R 6 31948244 31948244 NCIH647_LUNG 37 Missense_Mutation SNP G A uc003nyv.2 STK19_uc003nyt.... Hybrid_Cap... view
TLE1 9 84248428 84248428 NCIH647_LUNG 37 Intron SNP C G uc004alz.2 TLE1_uc004aly.2... Hybrid_Cap... view
TMEM123 11 102269398 102269398 NCIH647_LUNG 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TNFAIP3 p.H323Y 6 138198374 138198374 NCIH647_LUNG 37 Missense_Mutation SNP C T uc003qhr.2 TNFAIP3_uc003qh... Hybrid_Cap... view
TNNI3K p.K541Q 1 74833645 74833645 NCIH647_LUNG 37 Missense_Mutation SNP A C uc001dge.1 TNNI3K_uc001dgc... Hybrid_Cap... view
TOE1 p.A2A 1 45805930 45805930 NCIH647_LUNG 37 Silent SNP C T uc009vxq.2 MUTYH_uc001cnf.... Hybrid_Cap... view
TP53 p.S261_splice 17 7577498 7577498 NCIH647_LUNG 37 Splice_Site_SNP SNP C A uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TP63 3 189507518 189507519 NCIH647_LUNG 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TRRAP p.A2937S 7 98580890 98580890 NCIH647_LUNG 37 Missense_Mutation SNP G T uc003upp.2 TRRAP_uc011kis.... Hybrid_Cap... view
TTN p.I29914T 2 179407038 179407038 NCIH647_LUNG 37 Missense_Mutation SNP A G uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.A6345S 2 179586625 179586625 NCIH647_LUNG 37 Missense_Mutation SNP C A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 NCIH647_LUNG 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...