Annotation Summary for Cell Line: NCI-H660  

Cell line primary name: NCI-H660
Cell line aliases: H660
Gender: M
Site Primary: prostate
Histology: carcinoma
Hist Subtype1: small_cell_carcinoma
Notes:
Source: ATCC
Expression arrays: MAKER_p_NCLE_RNA7_HG-U133_Plus_2_B02_454586
SNP arrays: BOWER_p_NCLE_DNAAffy8_GenomeWideSNP_6_C11_464558
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in NCI-H660

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ABL2 1 179086419 179086420 NCIH660_PROSTAT... 37 Intron Ins - A rs72207641 uc001gmj.3 ABL2_uc010pnf.1... Hybrid_Cap...
ACACA 17 35766564 35766564 NCIH660_PROSTAT... 37 5'UTR Del A - uc002hno.2 ACACA_uc002hnn.... Hybrid_Cap...
ADAM17 2 9630245 9630245 NCIH660_PROSTAT... 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 NCIH660_PROSTAT... 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.R625W 6 151671399 151671399 NCIH660_PROSTAT... 37 Missense_Mutation SNP C T uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap... view
AKAP12 p.1531_1532insE 6 151674116 151674117 NCIH660_PROSTAT... 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP9 p.1335_1336insQ 7 91652178 91652179 NCIH660_PROSTAT... 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ALPK1 4 113347609 113347610 NCIH660_PROSTAT... 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 NCIH660_PROSTAT... 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
CDK18 p.I166T 1 205494274 205494274 NCIH660_PROSTAT... 37 Missense_Mutation SNP T C uc001hcr.2 CDK18_uc010pri.... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 NCIH660_PROSTAT... 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CXCL12 10 44873992 44873993 NCIH660_PROSTAT... 37 Intron Ins - CT rs117617571 uc001jbh.2 CXCL12_uc001jbf... Hybrid_Cap...
CYP17A1 p.R67H 10 104596919 104596919 NCIH660_PROSTAT... 37 Missense_Mutation SNP C T uc001kwg.2 Hybrid_Cap... view
DICER1 p.E1420del 14 95562995 95562997 NCIH660_PROSTAT... 37 In_Frame_Del Del TCC - uc001ydw.2 DICER1_uc010avh... Hybrid_Cap...
EGFR 7 55224580 55224580 NCIH660_PROSTAT... 37 Intron SNP G T rs41522547 uc003tqk.2 EGFR_uc003tqh.2... Hybrid_Cap... view
EPHA3 3 89156690 89156690 NCIH660_PROSTAT... 37 5'UTR SNP G A uc003dqy.2 EPHA3_uc003dqx.... Hybrid_Cap... view
EPHA6 3 97367230 97367231 NCIH660_PROSTAT... 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
ETV1 7 14028708 14028708 NCIH660_PROSTAT... 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FGFR1OP 6 167453519 167453520 NCIH660_PROSTAT... 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 NCIH660_PROSTAT... 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FMN2 p.PPLPGAGIPPP939del 1 240370914 240370946 NCIH660_PROSTAT... 37 In_Frame_Del Del GCCCC... - rs4997328;rs4997329 uc010pye.1 FMN2_uc010pyd.1... Hybrid_Cap...
FN1 2 216244182 216244185 NCIH660_PROSTAT... 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
FOXP1 3 71008341 71008342 NCIH660_PROSTAT... 37 3'UTR Ins - T rs11433724;rs114233617 uc003dol.2 FOXP1_uc003dom.... Hybrid_Cap...
GPR112 p.D2657del X 135474445 135474447 NCIH660_PROSTAT... 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 NCIH660_PROSTAT... 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 NCIH660_PROSTAT... 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HIF1A 14 62213929 62213930 NCIH660_PROSTAT... 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HNF1A 12 121434630 121434631 NCIH660_PROSTAT... 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
ILK 11 6630029 6630029 NCIH660_PROSTAT... 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ING1 p.P112S 13 111368124 111368124 NCIH660_PROSTAT... 37 Missense_Mutation SNP C T uc001vri.2 CARS2_uc010tjm.... Hybrid_Cap... view
ITPR2 p.R470_splice 12 26834804 26834805 NCIH660_PROSTAT... 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
JARID2 p.S90C 6 15410542 15410542 NCIH660_PROSTAT... 37 Missense_Mutation SNP C G uc003nbj.2 JARID2_uc011diu... Hybrid_Cap... view
KLK7 19 51480672 51480675 NCIH660_PROSTAT... 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 NCIH660_PROSTAT... 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 NCIH660_PROSTAT... 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K12 p.R27C 12 53881097 53881097 NCIH660_PROSTAT... 37 Missense_Mutation SNP G A uc001sdn.1 MAP3K12_uc001sd... Hybrid_Cap... view
MAP3K14 p.R218_splice 17 43364293 43364294 NCIH660_PROSTAT... 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAP3K8 p.L401R 10 30748359 30748359 NCIH660_PROSTAT... 37 Missense_Mutation SNP T G uc001ivi.1 MAP3K8_uc009xlf... Hybrid_Cap... view
MMP1 p.I191fs 11 102667447 102667447 NCIH660_PROSTAT... 37 Frame_Shift_Del Del A - uc001phi.2 MMP1_uc010ruv.1... Hybrid_Cap...
MYLK p.E1430_splice 3 123368043 123368044 NCIH660_PROSTAT... 37 Splice_Site_Ins Ins - G rs41431347 uc003ego.2 MYLK_uc010hrr.2... Hybrid_Cap...
MYST4 p.T640fs 10 76736014 76736014 NCIH660_PROSTAT... 37 Frame_Shift_Del Del C - uc001jwn.1 MYST4_uc001jwm.... Hybrid_Cap...
NAV3 p.M138I 12 78334913 78334913 NCIH660_PROSTAT... 37 Missense_Mutation SNP G C uc001syp.2 NAV3_uc001syo.2... Hybrid_Cap... view
NCAM1 11 112832307 112832308 NCIH660_PROSTAT... 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 NCIH660_PROSTAT... 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA3 p.QQQ1272del 20 46279815 46279823 NCIH660_PROSTAT... 37 In_Frame_Del Del GCAGC... - uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NEDD9 p.E411K 6 11190871 11190871 NCIH660_PROSTAT... 37 Missense_Mutation SNP C T uc003mzv.2 NEDD9_uc010joz.... Hybrid_Cap... view
NEDD9 p.A229S 6 11191417 11191417 NCIH660_PROSTAT... 37 Missense_Mutation SNP C A uc003mzv.2 NEDD9_uc010joz.... Hybrid_Cap... view
NEK3 p.K313_splice 13 52718050 52718051 NCIH660_PROSTAT... 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NOS3 p.G697A 7 150704342 150704342 NCIH660_PROSTAT... 37 Missense_Mutation SNP G C uc003wif.2 NOS3_uc011kuy.1... Hybrid_Cap... view
NR1H2 p.176_177insQ 19 50881820 50881821 NCIH660_PROSTAT... 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
PAX3 2 223158653 223158653 NCIH660_PROSTAT... 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAXIP1 p.Q663L 7 154755382 154755382 NCIH660_PROSTAT... 37 Missense_Mutation SNP T A uc003wlp.2 PAXIP1_uc003wlq... Hybrid_Cap... view
PDE4DIP p.Q1665fs 1 144873963 144873963 NCIH660_PROSTAT... 37 Frame_Shift_Del Del T - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDE4DIP p.V486fs 1 144917828 144917828 NCIH660_PROSTAT... 37 Frame_Shift_Del Del A - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PGGT1B 5 114548071 114548072 NCIH660_PROSTAT... 37 3'UTR Ins - C uc003kqw.3 PGGT1B_uc003kqx... Hybrid_Cap...
PIK3C2A 11 17111032 17111032 NCIH660_PROSTAT... 37 3'UTR SNP A C uc001mmq.3 PIK3C2A_uc009yg... Hybrid_Cap... view
PIK3C2G p.K1128fs 12 18691148 18691148 NCIH660_PROSTAT... 37 Frame_Shift_Del Del A - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PMS1 2 190670539 190670540 NCIH660_PROSTAT... 37 Intron Ins - A rs3214425 uc002urh.3 PMS1_uc010zga.1... Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 NCIH660_PROSTAT... 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 NCIH660_PROSTAT... 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
ROS1 p.R1425K 6 117674200 117674200 NCIH660_PROSTAT... 37 Missense_Mutation SNP C T uc003pxp.1 ROS1_uc011ebi.1... Hybrid_Cap... view
RPS6KL1 14 75373626 75373627 NCIH660_PROSTAT... 37 3'UTR Ins - TGAT uc001xqx.1 RPS6KL1_uc001xq... Hybrid_Cap...
SPEN p.A2653T 1 16260692 16260692 NCIH660_PROSTAT... 37 Missense_Mutation SNP G A uc001axk.1 SPEN_uc010obp.1... Hybrid_Cap... view
STK31 7 23872024 23872025 NCIH660_PROSTAT... 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TACC3 4 1746768 1746768 NCIH660_PROSTAT... 37 3'UTR SNP C G uc003gdo.2 TACC3_uc003gdp.... Hybrid_Cap... view
TEC 4 48139307 48139310 NCIH660_PROSTAT... 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TG p.T1001_splice 8 133909893 133909893 NCIH660_PROSTAT... 37 Splice_Site_SNP SNP G C uc003ytw.2 TG_uc010mdw.2_5... Hybrid_Cap... view
TG p.A1107D 8 133911145 133911145 NCIH660_PROSTAT... 37 Missense_Mutation SNP C A uc003ytw.2 TG_uc010mdw.2_5... Hybrid_Cap... view
TG p.C1728Y 8 133953737 133953737 NCIH660_PROSTAT... 37 Missense_Mutation SNP G A uc003ytw.2 TG_uc010mdw.2_M... Hybrid_Cap... view
TP63 3 189507518 189507519 NCIH660_PROSTAT... 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TSC1 p.P111A 9 135801006 135801006 NCIH660_PROSTAT... 37 Missense_Mutation SNP G C uc004cca.2 TSC1_uc004ccb.3... Hybrid_Cap... view
TTN 2 179391639 179391640 NCIH660_PROSTAT... 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.S33404I 2 179391800 179391800 NCIH660_PROSTAT... 37 Missense_Mutation SNP C A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.G30905S 2 179401057 179401057 NCIH660_PROSTAT... 37 Missense_Mutation SNP C T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 NCIH660_PROSTAT... 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...