Annotation Summary for Cell Line: NCI-H82  

Cell line primary name: NCI-H82
Cell line aliases: H82
Gender: M
Site Primary: lung
Histology: carcinoma
Hist Subtype1: small_cell_carcinoma
Notes:
Source: ATCC
Expression arrays: CASED_p_NCLE_RNA4_HG-U133_Plus_2_D08_383708
SNP arrays: FASTS_p_NCLE_DNAAffy4_S_GenomeWideSNP_6_E11_335304
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in NCI-H82

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 NCIH82_LUNG 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ACACA 17 35766564 35766564 NCIH82_LUNG 37 5'UTR Del A - uc002hno.2 ACACA_uc002hnn.... Hybrid_Cap...
ACVR1C 2 158390317 158390317 NCIH82_LUNG 37 3'UTR SNP T A uc002tzk.3 ACVR1C_uc002tzl... Hybrid_Cap... view
ADAM17 2 9630245 9630245 NCIH82_LUNG 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 NCIH82_LUNG 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AFF4 p.Q566P 5 132232625 132232625 NCIH82_LUNG 37 Missense_Mutation SNP T G uc003kyd.2 AFF4_uc011cxk.1... Hybrid_Cap... view
AKAP12 p.1531_1532insE 6 151674116 151674117 NCIH82_LUNG 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 NCIH82_LUNG 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ASPH 8 62602295 62602296 NCIH82_LUNG 37 Intron Ins - A rs78500357 uc003xuj.2 ASPH_uc011leg.1... Hybrid_Cap...
ASTN1 p.G5V 1 177133799 177133799 NCIH82_LUNG 37 Missense_Mutation SNP C A uc001glc.2 ASTN1_uc001glb.... Hybrid_Cap... view
AURKA p.R343Q 20 54945542 54945542 NCIH82_LUNG 37 Missense_Mutation SNP C T uc002xxd.1 AURKA_uc002xxe.... Hybrid_Cap... view
BCR 22 23631813 23631814 NCIH82_LUNG 37 Intron Ins - C rs66503844 uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BCR 22 23632777 23632778 NCIH82_LUNG 37 Intron Ins - T uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BTG1 12 92537706 92537707 NCIH82_LUNG 37 3'UTR Ins - T rs33983967 uc001tby.3 BTG1_uc001tbv.1... Hybrid_Cap...
CABC1 p.R598C 1 227174286 227174286 NCIH82_LUNG 37 Missense_Mutation SNP C T uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap... view
CASP1 11 104896960 104896960 NCIH82_LUNG 37 3'UTR SNP C A uc010rve.1 CASP1_uc001pig.... Hybrid_Cap... view
CDK11B 1 1654066 1654068 NCIH82_LUNG 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 NCIH82_LUNG 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CPNE5 p.R129H 6 36765960 36765960 NCIH82_LUNG 37 Missense_Mutation SNP C T uc003omr.1 CPNE5_uc003oms.... Hybrid_Cap... view
CREB3L2 p.T100del 7 137612914 137612916 NCIH82_LUNG 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CTBP2 p.K974fs 10 126678123 126678123 NCIH82_LUNG 37 Frame_Shift_Del Del T - uc001lie.3 CTBP2_uc009yak.... Hybrid_Cap...
CTTN p.Q372K 11 70277345 70277345 NCIH82_LUNG 37 Missense_Mutation SNP C A uc001opu.2 CTTN_uc001opv.3... Hybrid_Cap... view
DACH1 13 72014625 72014626 NCIH82_LUNG 37 3'UTR Ins - T rs117109529 uc010thn.1 DACH1_uc010tho.... Hybrid_Cap...
DDR2 1 162750211 162750212 NCIH82_LUNG 37 3'UTR Del TT - uc001gcf.2 DDR2_uc001gcg.2... Hybrid_Cap...
DNMT3B p.L282L 20 31379439 31379439 NCIH82_LUNG 37 Silent SNP G A uc002wyc.2 DNMT3B_uc010ztx... Hybrid_Cap... view
EDN1 6 12290729 12290729 NCIH82_LUNG 37 5'UTR Del A - uc003nae.3 EDN1_uc010jpb.2... Hybrid_Cap...
EIF4E 4 99808137 99808141 NCIH82_LUNG 37 Intron Del TTAAA - uc011ceb.1 EIF4E_uc011cea.... Hybrid_Cap...
EPHA10 p.M850T 1 38185594 38185594 NCIH82_LUNG 37 Missense_Mutation SNP A G uc009vvi.2 EPHA10_uc001cbt... Hybrid_Cap... view
EPHA3 p.K207N 3 89259477 89259477 NCIH82_LUNG 37 Missense_Mutation SNP G T uc003dqy.2 EPHA3_uc003dqx.... Hybrid_Cap... view
EPHA6 3 97367230 97367231 NCIH82_LUNG 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
ERBB2 17 37873794 37873794 NCIH82_LUNG 37 Intron SNP C T uc002hso.2 ERBB2_uc002hsm.... Hybrid_Cap... view
FBN2 p.G2520fs 5 127611764 127611764 NCIH82_LUNG 37 Frame_Shift_Del Del C - uc003kuu.2 Hybrid_Cap...
FER p.E345* 5 108219206 108219206 NCIH82_LUNG 37 Nonsense_Mutation SNP G T uc003kop.1 FER_uc011cvf.1_... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 NCIH82_LUNG 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FLI1 11 128638217 128638217 NCIH82_LUNG 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FN1 2 216244182 216244185 NCIH82_LUNG 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
FSCB p.A506P 14 44974675 44974675 NCIH82_LUNG 37 Missense_Mutation SNP C G uc001wvn.2 Hybrid_Cap... view
GCNT2 6 10586939 10586939 NCIH82_LUNG 37 Intron SNP A T uc010joo.2 GCNT2_uc010jol.... Hybrid_Cap... view
GPR112 p.D2657del X 135474445 135474447 NCIH82_LUNG 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 NCIH82_LUNG 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 NCIH82_LUNG 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HIF1A 14 62213929 62213930 NCIH82_LUNG 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HNF1A 12 121434630 121434631 NCIH82_LUNG 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
IL6ST p.Y380C 5 55251981 55251981 NCIH82_LUNG 37 Missense_Mutation SNP T C uc003jqq.2 IL6ST_uc010iwb.... Hybrid_Cap... view
ILK 11 6630029 6630029 NCIH82_LUNG 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITGB1 10 33197131 33197134 NCIH82_LUNG 37 Intron Del CTTT - rs116966876 uc001iwq.3 ITGB1_uc001iwp.... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 NCIH82_LUNG 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KDR 4 55970801 55970801 NCIH82_LUNG 37 Intron SNP T C uc003has.2 KDR_uc003hat.1_... Hybrid_Cap... view
KLK7 19 51480672 51480675 NCIH82_LUNG 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
KPNA5 p.L194V 6 117026247 117026247 NCIH82_LUNG 37 Missense_Mutation SNP C G uc003pxh.2 Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 NCIH82_LUNG 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP2K2 p.P269R 19 4099312 4099312 NCIH82_LUNG 37 Missense_Mutation SNP G C uc002lzk.2 MAP2K2_uc002lzj... Hybrid_Cap... view
MAP3K1 p.T949del 5 56177849 56177851 NCIH82_LUNG 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 NCIH82_LUNG 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MLLT6 17 36881873 36881873 NCIH82_LUNG 37 3'UTR Del C - uc002hqi.3 MLLT6_uc002hqk.... Hybrid_Cap...
NCAM1 11 112832307 112832308 NCIH82_LUNG 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 NCIH82_LUNG 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA1 p.E587D 2 24930100 24930100 NCIH82_LUNG 37 Missense_Mutation SNP G T uc002rfk.2 NCOA1_uc010eye.... Hybrid_Cap... view
NCOA2 p.S1211R 8 71040716 71040716 NCIH82_LUNG 37 Missense_Mutation SNP G T uc003xyn.1 NCOA2_uc011lfb.... Hybrid_Cap... view
NCOA3 p.QQQ1272del 20 46279815 46279823 NCIH82_LUNG 37 In_Frame_Del Del GCAGC... - uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NF1 p.S331R 17 29527544 29527544 NCIH82_LUNG 37 Missense_Mutation SNP T G uc002hgg.2 NF1_uc002hge.1_... Hybrid_Cap... view
NFKB1 p.D917_splice 4 103534740 103534741 NCIH82_LUNG 37 Splice_Site_Ins Ins - A rs35795162 uc011cep.1 NFKB1_uc011ceq.... Hybrid_Cap...
NOTCH1 p.V776M 9 139407871 139407871 NCIH82_LUNG 37 Missense_Mutation SNP C T uc004chz.2 NOTCH1_uc004cia... Hybrid_Cap... view
NPM1 5 170837734 170837734 NCIH82_LUNG 37 3'UTR Del T - uc011dex.1 NPM1_uc003mbi.2... Hybrid_Cap...
NPR1 1 153665919 153665920 NCIH82_LUNG 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 NCIH82_LUNG 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 NCIH82_LUNG 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NTRK1 p.R748W 1 156851285 156851285 NCIH82_LUNG 37 Missense_Mutation SNP C T uc001fqh.1 NTRK1_uc001fqf.... Hybrid_Cap... view
NUP98 p.F846L 11 3735087 3735087 NCIH82_LUNG 37 Missense_Mutation SNP G C uc001lyh.2 NUP98_uc001lyi.... Hybrid_Cap... view
PAX3 2 223158653 223158653 NCIH82_LUNG 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PBX1 p.T418T 1 164815874 164815874 NCIH82_LUNG 37 Silent SNP A G uc001gct.2 PBX1_uc010pku.1... Hybrid_Cap... view
PDE4DIP p.E243fs 1 144923729 144923729 NCIH82_LUNG 37 Frame_Shift_Del Del T - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDK4 7 95221928 95221928 NCIH82_LUNG 37 Intron Del A - uc003uoa.2 PDK4_uc003unz.2... Hybrid_Cap...
PHIP 6 79650265 79650266 NCIH82_LUNG 37 3'UTR Ins - TTTT rs70977753;rs13191571 uc003pir.2 PHIP_uc003piq.2... Hybrid_Cap...
PIK3C2G 12 18800990 18800990 NCIH82_LUNG 37 3'UTR Del A - rs16914368 uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PKHD1 p.L2811Q 6 51656042 51656042 NCIH82_LUNG 37 Missense_Mutation SNP A T uc003pah.1 PKHD1_uc010jzn.... Hybrid_Cap... view
PKN2 p.L384del 1 89250482 89250484 NCIH82_LUNG 37 In_Frame_Del Del TCT - uc001dmn.2 PKN2_uc001dmm.1... Hybrid_Cap...
POU5F1 6 31132300 31132300 NCIH82_LUNG 37 3'UTR SNP A G uc003nsv.2 POU5F1_uc003nsu... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 NCIH82_LUNG 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PRKG2 p.T519I 4 82058625 82058625 NCIH82_LUNG 37 Missense_Mutation SNP G A uc003hmh.2 PRKG2_uc011ccf.... Hybrid_Cap... view
RASGRF1 15 79277150 79277151 NCIH82_LUNG 37 Intron Ins - C rs67045840;rs77640668 uc002beq.2 RASGRF1_uc002be... Hybrid_Cap...
RB1 p.V314_splice 13 48941628 48941628 NCIH82_LUNG 37 Splice_Site_SNP SNP A T uc001vcb.2 RB1_uc010act.1_... Hybrid_Cap... view
RBL1 20 35627030 35627030 NCIH82_LUNG 37 3'UTR SNP T C uc002xgi.2 RBL1_uc010zvt.1... Hybrid_Cap... view
RECQL4 p.R766fs 8 145738768 145738768 NCIH82_LUNG 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RIF1 p.P1617L 2 152320884 152320884 NCIH82_LUNG 37 Missense_Mutation SNP C T uc002txm.2 RIF1_uc002txl.2... Hybrid_Cap... view
RNF130 5 179382600 179382600 NCIH82_LUNG 37 3'UTR SNP T C uc003mll.1 RNF130_uc003mlm... Hybrid_Cap... view
RPS6KA5 14 91360733 91360734 NCIH82_LUNG 37 Intron Ins - T rs77438853 uc001xys.2 RPS6KA5_uc010tw... Hybrid_Cap...
SDHC p.M87V 1 161326484 161326484 NCIH82_LUNG 37 Missense_Mutation SNP A G uc001gag.2 SDHC_uc001gai.2... Hybrid_Cap... view
SLC22A3 p.L339S 6 160857852 160857852 NCIH82_LUNG 37 Missense_Mutation SNP T C uc003qti.2 SLC22A3_uc011ef... Hybrid_Cap... view
SS18 p.Q369L 18 23612487 23612487 NCIH82_LUNG 37 Missense_Mutation SNP T A uc002kvm.2 SS18_uc002kvn.2... Hybrid_Cap... view
STK31 7 23872024 23872025 NCIH82_LUNG 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TCF12 p.S303T 15 57524992 57524992 NCIH82_LUNG 37 Missense_Mutation SNP G C uc002aea.2 TCF12_uc010ugm.... Hybrid_Cap... view
TCF21 6 134210497 134210498 NCIH82_LUNG 37 5'UTR Ins - TCTC rs35199378 uc003qei.3 TCF21_uc003qej.... Hybrid_Cap...
TEC p.Q471E 4 48147155 48147155 NCIH82_LUNG 37 Missense_Mutation SNP G C uc003gxz.2 Hybrid_Cap... view
THRAP3 p.E640D 1 36758200 36758200 NCIH82_LUNG 37 Missense_Mutation SNP G T uc001cae.3 THRAP3_uc001caf... Hybrid_Cap... view
TMEM123 11 102269398 102269398 NCIH82_LUNG 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TP63 3 189507518 189507519 NCIH82_LUNG 37 Intron Ins - AG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TRPS1 8 116635872 116635873 NCIH82_LUNG 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TTBK1 p.E771del 6 43250726 43250728 NCIH82_LUNG 37 In_Frame_Del Del GAA - uc003ouq.1 Hybrid_Cap...
TTN 2 179391639 179391640 NCIH82_LUNG 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.D25166E 2 179427657 179427657 NCIH82_LUNG 37 Missense_Mutation SNP A T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
UBE3B p.P982S 12 109971292 109971292 NCIH82_LUNG 37 Missense_Mutation SNP C T uc001top.2 UBE3B_uc001toq.... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 NCIH82_LUNG 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
ZFYVE9 1 52729677 52729677 NCIH82_LUNG 37 Intron SNP A G uc001cto.2 ZFYVE9_uc001ctn... Hybrid_Cap... view
ZNF217 p.S394P 20 52198186 52198186 NCIH82_LUNG 37 Missense_Mutation SNP A G uc002xwq.3 ZNF217_uc010gij... Hybrid_Cap... view
ZNF331 p.R94C 19 54080094 54080094 NCIH82_LUNG 37 Missense_Mutation SNP C T uc002qbx.1 ZNF331_uc002qby... Hybrid_Cap... view