Annotation Summary for Cell Line: NCI-H841  

Cell line primary name: NCI-H841
Cell line aliases: H841
Gender: M
Site Primary: lung
Histology: carcinoma
Hist Subtype1: small_cell_carcinoma
Notes:
Source: ATCC
Expression arrays: WATCH_p_NCLE_RNA8_HG-U133_Plus_2_B09_474584
SNP arrays: AWASH_p_NCLE_DNAAffy10_GenomeWideSNP_6_D04_542788
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in NCI-H841

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ADAM17 2 9630245 9630245 NCIH841_LUNG 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 NCIH841_LUNG 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 NCIH841_LUNG 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP6 14 33201982 33201983 NCIH841_LUNG 37 Intron Ins - T rs71868172 uc001wrq.2 AKAP6_uc010aml.... Hybrid_Cap...
AKAP9 p.1335_1336insQ 7 91652178 91652179 NCIH841_LUNG 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ALPK2 p.1388_1389FF>F 18 56203253 56203255 NCIH841_LUNG 37 In_Frame_Del Del AAG - uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ATRX p.M366I X 76939650 76939650 NCIH841_LUNG 37 Missense_Mutation SNP C A uc004ecp.3 ATRX_uc004ecq.3... Hybrid_Cap... view
BCL11A p.H724Y 2 60687877 60687877 NCIH841_LUNG 37 Missense_Mutation SNP G A uc002sae.1 BCL11A_uc002sab... Hybrid_Cap... view
CAD p.G400C 2 27447302 27447302 NCIH841_LUNG 37 Missense_Mutation SNP G T uc002rji.2 CAD_uc010eyw.2_... Hybrid_Cap... view
CDK11B 1 1654066 1654068 NCIH841_LUNG 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CHD1 p.P1684del 5 98192165 98192167 NCIH841_LUNG 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CHD9 p.K1588* 16 53307582 53307582 NCIH841_LUNG 37 Nonsense_Mutation SNP A T uc002ehb.2 CHD9_uc002egy.2... Hybrid_Cap... view
CHD9 p.2164_2165SS>S 16 53338410 53338412 NCIH841_LUNG 37 In_Frame_Del Del TTC - uc002ehb.2 CHD9_uc002egy.2... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 NCIH841_LUNG 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN6 3 1339681 1339686 NCIH841_LUNG 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
COL18A1 p.R1606fs 21 46930062 46930063 NCIH841_LUNG 37 Frame_Shift_Ins Ins - G uc011afs.1 COL18A1_uc002zh... Hybrid_Cap...
COL18A1 p.R1395H 21 46925127 46925127 NCIH841_LUNG 37 Missense_Mutation SNP G A uc011afs.1 COL18A1_uc002zh... Hybrid_Cap... view
CREB3L2 p.T100del 7 137612914 137612916 NCIH841_LUNG 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CSNK1A1 5 148930660 148930660 NCIH841_LUNG 37 5'UTR SNP G C rs11556830 uc003lqw.1 CSNK1A1_uc011dc... Hybrid_Cap... view
DDR2 1 162750211 162750212 NCIH841_LUNG 37 3'UTR Del TT - uc001gcf.2 DDR2_uc001gcg.2... Hybrid_Cap...
DLC1 8 12943085 12943086 NCIH841_LUNG 37 3'UTR Ins - T rs60094700 uc003wwm.2 DLC1_uc003wwk.1... Hybrid_Cap...
DNAH8 6 38952247 38952250 NCIH841_LUNG 37 Intron Del CACA - uc003ooe.1 DNAH8_uc003oog.... Hybrid_Cap...
DYRK1A 21 38884966 38884967 NCIH841_LUNG 37 3'UTR Ins - T rs72430212 uc002ywk.2 DYRK1A_uc002ywi... Hybrid_Cap...
EDN1 6 12290729 12290729 NCIH841_LUNG 37 5'UTR Del A - uc003nae.3 EDN1_uc010jpb.2... Hybrid_Cap...
EIF2AK2 2 37334185 37334186 NCIH841_LUNG 37 3'UTR Ins - A rs66470022 uc010ynh.1 EIF2AK2_uc010fa... Hybrid_Cap...
EPHA6 3 97367230 97367231 NCIH841_LUNG 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
FAM132A 1 1177919 1177919 NCIH841_LUNG 37 3'UTR Del T - uc001adl.1 Hybrid_Cap...
FGFR1OP 6 167453519 167453520 NCIH841_LUNG 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 NCIH841_LUNG 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLI1 11 128638217 128638217 NCIH841_LUNG 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FMO4 p.C440* 1 171310621 171310621 NCIH841_LUNG 37 Nonsense_Mutation SNP C A uc001gho.2 Hybrid_Cap... view
GCNT2 6 10626963 10626963 NCIH841_LUNG 37 3'UTR SNP C T uc010joo.2 GCNT2_uc010jol.... Hybrid_Cap... view
GLI3 p.R1182W 7 42005127 42005127 NCIH841_LUNG 37 Missense_Mutation SNP G A uc011kbh.1 GLI3_uc011kbg.1... Hybrid_Cap... view
GRIA3 X 122318386 122318387 NCIH841_LUNG 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GRK6 p.A292V 5 176861051 176861051 NCIH841_LUNG 37 Missense_Mutation SNP C T uc011dfz.1 GRK6_uc003mgp.2... Hybrid_Cap... view
GUCY2C 12 14827464 14827466 NCIH841_LUNG 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HECW1 p.S696L 7 43484858 43484858 NCIH841_LUNG 37 Missense_Mutation SNP C T uc003tid.1 HECW1_uc011kbi.... Hybrid_Cap... view
HIF1A 14 62213929 62213930 NCIH841_LUNG 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HNF1A 12 121434630 121434631 NCIH841_LUNG 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
HORMAD1 p.R335del 1 150675811 150675813 NCIH841_LUNG 37 In_Frame_Del Del CTT - uc001evk.1 HORMAD1_uc001ev... Hybrid_Cap...
IL17RD p.R401T 3 57132529 57132529 NCIH841_LUNG 37 Missense_Mutation SNP C G uc003dil.2 IL17RD_uc003dik... Hybrid_Cap... view
ILK 11 6630029 6630029 NCIH841_LUNG 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITGB1 10 33197131 33197134 NCIH841_LUNG 37 Intron Del CTTT - rs116966876 uc001iwq.3 ITGB1_uc001iwp.... Hybrid_Cap...
KLK7 19 51480672 51480675 NCIH841_LUNG 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LZTR1 22 21351683 21351683 NCIH841_LUNG 37 3'UTR SNP G A uc002zto.2 LZTR1_uc002ztn.... Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 NCIH841_LUNG 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP2K1 15 66679649 66679650 NCIH841_LUNG 37 5'UTR Ins - C rs67229745 uc010bhq.2 Hybrid_Cap...
MAP2K5 15 67951229 67951229 NCIH841_LUNG 37 Intron Del A - uc002aqu.2 MAP2K5_uc002aqt... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 NCIH841_LUNG 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 NCIH841_LUNG 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAP3K6 1 27681878 27681878 NCIH841_LUNG 37 3'UTR SNP G A uc001bny.1 MAP3K6_uc009vsw... Hybrid_Cap... view
MAP3K6 p.A349V 1 27689438 27689438 NCIH841_LUNG 37 Missense_Mutation SNP G A uc001bny.1 MAP3K6_uc009vsw... Hybrid_Cap... view
MCM3AP 21 47667038 47667038 NCIH841_LUNG 37 Intron Del T - uc002zir.1 MCM3APAS_uc002z... Hybrid_Cap...
MCM3APAS 21 47671275 47671276 NCIH841_LUNG 37 3'UTR Ins - AAT rs67797185 uc002zin.2 MCM3APAS_uc002z... Hybrid_Cap...
MLL3 p.Q3016H 7 151873490 151873490 NCIH841_LUNG 37 Missense_Mutation SNP T G uc003wla.2 MLL3_uc003wkz.2... Hybrid_Cap... view
MLL3 p.Y816fs 7 151945071 151945072 NCIH841_LUNG 37 Frame_Shift_Ins Ins - T uc003wla.2 Hybrid_Cap...
MSH3 p.PPA66del 5 79950742 79950750 NCIH841_LUNG 37 In_Frame_Del Del CCCCC... - rs60484572;rs1047489 uc003kgz.2 DHFR_uc011ctl.1... Hybrid_Cap...
MTUS2 13 30077481 30077481 NCIH841_LUNG 37 3'UTR SNP C G uc001usl.3 MTUS2_uc001usm.... Hybrid_Cap... view
NCAM1 11 112832307 112832308 NCIH841_LUNG 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 NCIH841_LUNG 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NFIA 1 61921185 61921186 NCIH841_LUNG 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NPM1 5 170837734 170837734 NCIH841_LUNG 37 3'UTR Del T - uc011dex.1 NPM1_uc003mbi.2... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 NCIH841_LUNG 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NTRK3 15 88420005 88420005 NCIH841_LUNG 37 3'UTR Del T - uc002bme.1 NTRK3_uc002bmh.... Hybrid_Cap...
PAX3 2 223158653 223158653 NCIH841_LUNG 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAXIP1 7 154735785 154735785 NCIH841_LUNG 37 3'UTR SNP C T uc003wlp.2 LOC100132707_uc... Hybrid_Cap... view
PCM1 8 17885407 17885408 NCIH841_LUNG 37 3'UTR Ins - T rs117750062 uc003wyi.3 PCM1_uc011kyh.1... Hybrid_Cap...
PDE4DIP 1 144863860 144863861 NCIH841_LUNG 37 Intron Ins - T rs33949841 uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDIK1L 1 26449336 26449337 NCIH841_LUNG 37 3'UTR Del AA - rs79778025 uc010oew.1 PDIK1L_uc001blj... Hybrid_Cap...
PER1 17 8047830 8047830 NCIH841_LUNG 37 Intron SNP G A uc002gkd.2 PER1_uc010cns.2... Hybrid_Cap... view
PGR 11 100933598 100933599 NCIH841_LUNG 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PI4K2A p.D329E 10 99424644 99424644 NCIH841_LUNG 37 Missense_Mutation SNP C A uc001kog.1 PI4K2A_uc010qoy... Hybrid_Cap... view
PIP4K2A p.G330R 10 22830781 22830781 NCIH841_LUNG 37 Missense_Mutation SNP C T uc001irl.3 PIP4K2A_uc010qc... Hybrid_Cap... view
PRKCH 14 61788636 61788636 NCIH841_LUNG 37 5'UTR SNP A G uc001xfn.2 PRKCH_uc010tsa.... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 NCIH841_LUNG 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PTPRD p.Q748R 9 8499726 8499726 NCIH841_LUNG 37 Missense_Mutation SNP T C uc003zkk.2 PTPRD_uc003zkp.... Hybrid_Cap... view
RAPGEF2 4 160189200 160189201 NCIH841_LUNG 37 5'UTR Ins - T rs72011511 uc003iqg.3 Hybrid_Cap...
RET 10 43623815 43623815 NCIH841_LUNG 37 3'UTR SNP G A uc001jal.2 Hybrid_Cap... view
RICTOR p.R324K 5 38971980 38971980 NCIH841_LUNG 37 Missense_Mutation SNP C T uc003jlo.2 RICTOR_uc003jlp... Hybrid_Cap... view
RPS6KC1 p.N931K 1 213415612 213415612 NCIH841_LUNG 37 Missense_Mutation SNP C G uc010ptr.1 RPS6KC1_uc001hk... Hybrid_Cap... view
SEPT3 p.E243D 22 42387636 42387636 NCIH841_LUNG 37 Missense_Mutation SNP G C uc003bbr.3 WBP2NL_uc011ape... Hybrid_Cap... view
SGK196 8 42978201 42978201 NCIH841_LUNG 37 3'UTR Del T - uc003xpw.2 Hybrid_Cap...
SMARCA4 p.K934* 19 11132584 11132584 NCIH841_LUNG 37 Nonsense_Mutation SNP A T uc010dxo.2 SMARCA4_uc002mq... Hybrid_Cap... view
SORL1 p.G819R 11 121425911 121425911 NCIH841_LUNG 37 Missense_Mutation SNP G C uc001pxx.2 Hybrid_Cap... view
SRPK1 p.K268R 6 35838246 35838246 NCIH841_LUNG 37 Missense_Mutation SNP T C uc003olj.2 SRPK1_uc011dtg.... Hybrid_Cap... view
STK25 2 242435659 242435662 NCIH841_LUNG 37 Intron Del AAGG - rs3215138;rs75497042 uc002wbm.2 STK25_uc002wbk.... Hybrid_Cap...
STK31 7 23872024 23872025 NCIH841_LUNG 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
STK40 p.R4* 1 36826924 36826924 NCIH841_LUNG 37 Nonsense_Mutation SNP T A uc001cal.1 STK40_uc001cak.... Hybrid_Cap... view
STRADA 17 61781331 61781332 NCIH841_LUNG 37 Intron Ins - AGAACC rs66701913 uc002jbm.2 STRADA_uc002jbn... Hybrid_Cap...
TAL1 p.S286A 1 47685532 47685532 NCIH841_LUNG 37 Missense_Mutation SNP A C uc001cqx.2 TAL1_uc009vyq.2... Hybrid_Cap... view
TMEM123 11 102269398 102269398 NCIH841_LUNG 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TNFRSF11B p.G127E 8 119945190 119945190 NCIH841_LUNG 37 Missense_Mutation SNP C T uc003yon.3 TNFRSF11B_uc010... Hybrid_Cap... view
TOX p.P340S 8 59728271 59728271 NCIH841_LUNG 37 Missense_Mutation SNP G A uc003xtw.1 Hybrid_Cap... view
TP53 p.C242S 17 7577556 7577556 NCIH841_LUNG 37 Missense_Mutation SNP C G uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TP63 3 189507518 189507519 NCIH841_LUNG 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TRPS1 8 116635872 116635873 NCIH841_LUNG 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TSC1 9 135771333 135771333 NCIH841_LUNG 37 3'UTR Del A - rs115091888 uc004cca.2 TSC1_uc004ccb.3... Hybrid_Cap...
VEGFC p.S419_splice 4 177605082 177605084 NCIH841_LUNG 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
ZMYM2 p.N842I 13 20632746 20632746 NCIH841_LUNG 37 Missense_Mutation SNP A T uc001umr.2 ZMYM2_uc001ums.... Hybrid_Cap... view