Annotation Summary for Cell Line: OS-RC-2  

Cell line primary name: OS-RC-2
Cell line aliases:
Gender:
Site Primary: kidney
Histology: carcinoma
Hist Subtype1: renal_cell_carcinoma
Notes:
Source: RIKEN
Expression arrays: BITTS_p_NCLE_RNA12_HG-U133_Plus_2_C08_698810
SNP arrays: EPHOR_p_NCLE_Achilles_DNAAffy15_GenomeWideSNP_6_C10_780376
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in OS-RC-2

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 OSRC2_KIDNEY 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 OSRC2_KIDNEY 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
AMZ2 p.R263* 17 66251877 66251877 OSRC2_KIDNEY 37 Nonsense_Mutation SNP C T uc002jgs.1 AMZ2_uc002jgr.1... Hybrid_Cap... view
APC p.F2462S 5 112178676 112178676 OSRC2_KIDNEY 37 Missense_Mutation SNP T C uc010jby.2 APC_uc011cvt.1_... Hybrid_Cap... view
ARNT p.P706L 1 150785811 150785811 OSRC2_KIDNEY 37 Missense_Mutation SNP G A rs2275237 uc001evr.1 ARNT_uc010pck.1... Hybrid_Cap... view
ASPH p.A264_splice 8 62550924 62550925 OSRC2_KIDNEY 37 Splice_Site_Ins Ins - A rs5891816 uc003xuj.2 ASPH_uc011leg.1... Hybrid_Cap...
BMPR1A 10 88635691 88635691 OSRC2_KIDNEY 37 5'UTR SNP C A uc001kdy.2 Hybrid_Cap... view
BTRC p.R598Q 10 103310592 103310592 OSRC2_KIDNEY 37 Missense_Mutation SNP G A uc001kta.2 BTRC_uc001ktb.2... Hybrid_Cap... view
CACNB2 10 18828721 18828722 OSRC2_KIDNEY 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CDC42BPA p.D254Y 1 227335194 227335194 OSRC2_KIDNEY 37 Missense_Mutation SNP C A uc001hqr.2 CDC42BPA_uc001h... Hybrid_Cap... view
CHRNA5 15 78885615 78885616 OSRC2_KIDNEY 37 3'UTR Ins - TA rs72534078 uc002bdy.2 CHRNA3_uc002bea... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 OSRC2_KIDNEY 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN5 p.D598Y 11 100064303 100064303 OSRC2_KIDNEY 37 Missense_Mutation SNP G T uc001pga.2 CNTN5_uc009ywv.... Hybrid_Cap... view
CNTN6 3 1339681 1339686 OSRC2_KIDNEY 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
CTBP2 p.K974fs 10 126678123 126678123 OSRC2_KIDNEY 37 Frame_Shift_Del Del T - uc001lie.3 CTBP2_uc009yak.... Hybrid_Cap...
DDX10 p.G694R 11 108709287 108709287 OSRC2_KIDNEY 37 Missense_Mutation SNP G C uc001pkm.2 DDX10_uc001pkl.... Hybrid_Cap... view
DNMT3B p.R440fs 20 31384616 31384617 OSRC2_KIDNEY 37 Frame_Shift_Ins Ins - G uc002wyc.2 DNMT3B_uc010ztx... Hybrid_Cap...
DYRK1A 21 38884966 38884967 OSRC2_KIDNEY 37 3'UTR Ins - T rs72430212 uc002ywk.2 DYRK1A_uc002ywi... Hybrid_Cap...
EGF p.E1134fs 4 110932389 110932390 OSRC2_KIDNEY 37 Frame_Shift_Ins Ins - C rs11569144 uc003hzy.3 EGF_uc011cfu.1_... Hybrid_Cap...
EPHA4 2 222290623 222290624 OSRC2_KIDNEY 37 3'UTR Ins - T uc002vmq.2 EPHA4_uc002vmr.... Hybrid_Cap...
EPHA6 3 97367230 97367231 OSRC2_KIDNEY 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
FBXW7 p.117_118insEE 4 153332604 153332605 OSRC2_KIDNEY 37 In_Frame_Ins Ins - CTCCTC uc003ims.2 FBXW7_uc011cii.... Hybrid_Cap...
FGFR1OP 6 167453519 167453520 OSRC2_KIDNEY 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FLI1 11 128638217 128638217 OSRC2_KIDNEY 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLT4 p.Y203* 5 180057010 180057010 OSRC2_KIDNEY 37 Nonsense_Mutation SNP G T uc003mlz.3 FLT4_uc003mma.3... Hybrid_Cap... view
FOXP1 3 71008341 71008342 OSRC2_KIDNEY 37 3'UTR Ins - T rs11433724;rs114233617 uc003dol.2 FOXP1_uc003dom.... Hybrid_Cap...
GLI1 p.P87S 12 57858521 57858521 OSRC2_KIDNEY 37 Missense_Mutation SNP C T uc001snx.2 GLI1_uc009zpp.2... Hybrid_Cap... view
GPR112 p.D2657del X 135474445 135474447 OSRC2_KIDNEY 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 OSRC2_KIDNEY 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 OSRC2_KIDNEY 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HSP90B1 p.E791del 12 104341188 104341190 OSRC2_KIDNEY 37 In_Frame_Del Del GAA - rs117491163 uc001tkb.1 HSP90B1_uc010sw... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 OSRC2_KIDNEY 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KDM5A 12 498268 498268 OSRC2_KIDNEY 37 5'UTR Del G - uc001qif.1 KDM5A_uc001qie.... Hybrid_Cap...
KLK7 19 51480672 51480675 OSRC2_KIDNEY 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LAMA1 p.S155S 18 7050816 7050816 OSRC2_KIDNEY 37 Silent SNP G A uc002knm.2 LAMA1_uc010wzj.... Hybrid_Cap... view
MAP3K14 p.R218_splice 17 43364293 43364294 OSRC2_KIDNEY 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAPKBP1 p.E694K 15 42110473 42110473 OSRC2_KIDNEY 37 Missense_Mutation SNP G A uc001zok.3 MAPKBP1_uc001zo... Hybrid_Cap... view
MAST3 p.D1132V 19 18260001 18260001 OSRC2_KIDNEY 37 Missense_Mutation SNP A T uc002nhz.3 Hybrid_Cap... view
MLL3 p.Y816fs 7 151945071 151945072 OSRC2_KIDNEY 37 Frame_Shift_Ins Ins - T uc003wla.2 Hybrid_Cap...
MST1R 3 49941114 49941114 OSRC2_KIDNEY 37 5'UTR SNP C A uc003cxy.3 MST1R_uc011bdd.... Hybrid_Cap... view
MYH9 p.A1732G 22 36681783 36681783 OSRC2_KIDNEY 37 Missense_Mutation SNP G C uc003apg.2 Hybrid_Cap... view
MYLK p.E1066del 3 123419117 123419119 OSRC2_KIDNEY 37 In_Frame_Del Del TTC - rs72491150 uc003ego.2 MYLK_uc011bjw.1... Hybrid_Cap...
NCAM1 11 112832307 112832308 OSRC2_KIDNEY 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 OSRC2_KIDNEY 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NF1 p.K2456K 17 29677247 29677247 OSRC2_KIDNEY 37 Silent SNP A G uc002hgg.2 NF1_uc002hgh.2_... Hybrid_Cap... view
NPAT p.R230Q 11 108057246 108057246 OSRC2_KIDNEY 37 Missense_Mutation SNP C T uc001pjz.3 NPAT_uc001pka.2... Hybrid_Cap... view
NPR1 1 153665919 153665920 OSRC2_KIDNEY 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 OSRC2_KIDNEY 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
OBSCN p.R1129Q 1 228432177 228432177 OSRC2_KIDNEY 37 Missense_Mutation SNP G A uc009xez.1 OBSCN_uc001hsn.... Hybrid_Cap... view
OBSCN p.P6813R 1 228558917 228558917 OSRC2_KIDNEY 37 Missense_Mutation SNP C G uc009xez.1 OBSCN_uc001hsr.... Hybrid_Cap... view
PDK4 7 95221928 95221928 OSRC2_KIDNEY 37 Intron Del A - uc003uoa.2 PDK4_uc003unz.2... Hybrid_Cap...
PIK3C2G p.P129del 12 18435399 18435401 OSRC2_KIDNEY 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PRKACA p.T52T 19 14217653 14217653 OSRC2_KIDNEY 37 Silent SNP C T uc002myc.2 PRKACA_uc002myb... Hybrid_Cap... view
PRKCA 17 64298959 64298960 OSRC2_KIDNEY 37 5'UTR Ins - G rs71160558 uc002jfp.1 PRKCA_uc002jfo.... Hybrid_Cap...
PRKCG p.H445R 19 54403539 54403539 OSRC2_KIDNEY 37 Missense_Mutation SNP A G uc010yeg.1 PRKCG_uc002qcq.... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 OSRC2_KIDNEY 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PTEN p.N212_splice 10 89712013 89712028 OSRC2_KIDNEY 37 Splice_Site_Del Del TGCAG... - uc001kfb.2 Hybrid_Cap...
RASGRF1 15 79277150 79277151 OSRC2_KIDNEY 37 Intron Ins - C rs67045840;rs77640668 uc002beq.2 RASGRF1_uc002be... Hybrid_Cap...
RB1 13 49054334 49054334 OSRC2_KIDNEY 37 3'UTR SNP A G uc001vcb.2 Hybrid_Cap... view
RPS6KA1 p.I638V 1 26898722 26898722 OSRC2_KIDNEY 37 Missense_Mutation SNP A G uc001bms.1 RPS6KA1_uc001bm... Hybrid_Cap... view
SDHB p.W218* 1 17349214 17349214 OSRC2_KIDNEY 37 Nonsense_Mutation SNP C T uc001bae.2 Hybrid_Cap... view
SORL1 p.M2011V 11 121491914 121491914 OSRC2_KIDNEY 37 Missense_Mutation SNP A G uc001pxx.2 SORL1_uc010rzp.... Hybrid_Cap... view
TGFB3 14 76425406 76425406 OSRC2_KIDNEY 37 3'UTR SNP G T uc001xsc.2 Hybrid_Cap... view
TIE1 p.V413M 1 43775107 43775107 OSRC2_KIDNEY 37 Missense_Mutation SNP G A uc001ciu.2 TIE1_uc010okd.1... Hybrid_Cap... view
TLK1 2 171850178 171850179 OSRC2_KIDNEY 37 3'UTR Ins - AA rs71008739 uc002ugo.2 TLK1_uc002ugn.2... Hybrid_Cap...
TP63 3 189507518 189507519 OSRC2_KIDNEY 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TTN 2 179391639 179391640 OSRC2_KIDNEY 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.Y29510C 2 179408638 179408638 OSRC2_KIDNEY 37 Missense_Mutation SNP T C uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.N16795S 2 179459133 179459133 OSRC2_KIDNEY 37 Missense_Mutation SNP T C uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.V9839_splice 2 179546102 179546102 OSRC2_KIDNEY 37 Splice_Site_SNP SNP C T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
UBE3B 12 109947357 109947358 OSRC2_KIDNEY 37 Intron Ins - T uc001top.2 UBE3B_uc001toq.... Hybrid_Cap...
UBR5 p.I48V 8 103373400 103373400 OSRC2_KIDNEY 37 Missense_Mutation SNP T C uc003ykr.1 UBR5_uc003yks.1... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 OSRC2_KIDNEY 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
WT1 p.G351R 11 32421541 32421541 OSRC2_KIDNEY 37 Missense_Mutation SNP C T uc001mtn.1 WT1_uc001mtl.1_... Hybrid_Cap... view