Annotation Summary for Cell Line: OV-90  

Cell line primary name: OV-90
Cell line aliases:
Gender: F
Site Primary: ovary
Histology: carcinoma
Hist Subtype1: mixed_carcinoma
Notes:
Source: ATCC
Expression arrays: BRAKE_p_NCLE_RNA2_HG-U133_Plus_2_A02_241044
SNP arrays: LIMPS_p_NCLE_DNA2N_GenomeWideSNP_6_D02_246684
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in OV-90

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 OV90_OVARY 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
AATK p.G772R 17 79095422 79095422 OV90_OVARY 37 Missense_Mutation SNP C T uc010dia.2 AATK_uc010dhz.2... Hybrid_Cap... view
ADAM17 2 9630241 9630245 OV90_OVARY 37 3'UTR Del TTGAT - rs3833563 uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM17 2 9630245 9630245 OV90_OVARY 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 OV90_OVARY 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AFF4 p.P623R 5 132232454 132232454 OV90_OVARY 37 Missense_Mutation SNP G C uc003kyd.2 AFF4_uc011cxk.1... Hybrid_Cap... view
ALPK1 4 113347609 113347610 OV90_OVARY 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 OV90_OVARY 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ARAF X 47430973 47430973 OV90_OVARY 37 3'UTR SNP C T uc011mlq.1 Hybrid_Cap... view
BCR p.A666G 22 23615843 23615843 OV90_OVARY 37 Missense_Mutation SNP C G uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap... view
BCR p.Q1263* 22 23657680 23657680 OV90_OVARY 37 Nonsense_Mutation SNP C T uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap... view
BCR 22 23657919 23657920 OV90_OVARY 37 3'UTR Ins - G uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BMP4 14 54416601 54416602 OV90_OVARY 37 3'UTR Ins - AT rs74495140;rs76335800 uc001xal.3 BMP4_uc010aoh.2... Hybrid_Cap...
CDK11B 1 1654066 1654068 OV90_OVARY 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CDKN2A p.C141* 9 21971101 21971101 OV90_OVARY 37 Nonsense_Mutation SNP G T uc003zpl.2 MTAP_uc003zpi.1... Hybrid_Cap... view
CHD9 p.2164_2165SS>S 16 53338410 53338412 OV90_OVARY 37 In_Frame_Del Del TTC - uc002ehb.2 CHD9_uc002egy.2... Hybrid_Cap...
CHIC2 4 54876132 54876132 OV90_OVARY 37 3'UTR Del C - rs4437313 uc003haj.1 PDGFRA_uc003haa... Hybrid_Cap...
CREB3L2 p.T100del 7 137612914 137612916 OV90_OVARY 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CSMD3 p.A237G 8 114111192 114111192 OV90_OVARY 37 Missense_Mutation SNP G C uc003ynu.2 CSMD3_uc003ynt.... Hybrid_Cap... view
CXCL12 10 44873992 44873993 OV90_OVARY 37 Intron Ins - CT rs117617571 uc001jbh.2 CXCL12_uc001jbf... Hybrid_Cap...
DYRK1A 21 38884966 38884967 OV90_OVARY 37 3'UTR Ins - T rs72430212 uc002ywk.2 DYRK1A_uc002ywi... Hybrid_Cap...
EPHA6 3 97367230 97367231 OV90_OVARY 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
ERCC2 19 45854768 45854768 OV90_OVARY 37 3'UTR Del G - uc002pbj.2 KLC3_uc002pbf.1... Hybrid_Cap...
ESR1 p.S561S 6 152419990 152419990 OV90_OVARY 37 Silent SNP C T uc010kio.2 ESR1_uc003qom.3... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 OV90_OVARY 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR4 p.P352L 5 176519783 176519783 OV90_OVARY 37 Missense_Mutation SNP C T uc003mfl.2 FGFR4_uc003mfm.... Hybrid_Cap... view
FLI1 11 128638217 128638217 OV90_OVARY 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLT1 13 28903963 28903963 OV90_OVARY 37 Intron SNP G A uc001usb.3 FLT1_uc010aaq.2... Hybrid_Cap... view
FLT4 5 180035183 180035185 OV90_OVARY 37 Intron Del AGT - uc003mlz.3 FLT4_uc003mma.3... Hybrid_Cap...
FMN2 p.PPPPLPGAAIP948del 1 240370942 240370974 OV90_OVARY 37 In_Frame_Del Del CCTCC... - rs72444563 uc010pye.1 FMN2_uc010pyd.1... Hybrid_Cap...
FN1 2 216244182 216244185 OV90_OVARY 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
FZD1 p.93_94insP 7 90894459 90894460 OV90_OVARY 37 In_Frame_Ins Ins - CCG uc003ula.2 Hybrid_Cap...
GOLGA5 14 93305931 93305932 OV90_OVARY 37 3'UTR Ins - AA uc001yaz.1 GOLGA5_uc001yba... Hybrid_Cap...
GPR112 p.D2657del X 135474445 135474447 OV90_OVARY 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318372 122318372 OV90_OVARY 37 5'UTR SNP T C uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap... view
GRIA3 X 122318386 122318387 OV90_OVARY 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 OV90_OVARY 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HDAC4 2 240011617 240011617 OV90_OVARY 37 Intron SNP G C uc002vyk.3 HDAC4_uc010fyz.... Hybrid_Cap... view
HIF1A 14 62213929 62213930 OV90_OVARY 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HNF1A 12 121434630 121434631 OV90_OVARY 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
HSP90B1 p.E791del 12 104341188 104341190 OV90_OVARY 37 In_Frame_Del Del GAA - rs117491163 uc001tkb.1 HSP90B1_uc010sw... Hybrid_Cap...
HUNK p.R168L 21 33297021 33297021 OV90_OVARY 37 Missense_Mutation SNP G T uc002yph.2 Hybrid_Cap... view
ILK 11 6630029 6630029 OV90_OVARY 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
INHBA 7 41729121 41729122 OV90_OVARY 37 3'UTR Ins - T uc003thq.2 INHBA_uc003thr.... Hybrid_Cap...
ITGB1 10 33197131 33197134 OV90_OVARY 37 Intron Del CTTT - rs116966876 uc001iwq.3 ITGB1_uc001iwp.... Hybrid_Cap...
ITGB4 p.A1033T 17 73739928 73739928 OV90_OVARY 37 Missense_Mutation SNP G A uc002jpg.2 ITGB4_uc002jph.... Hybrid_Cap... view
KLK7 19 51480672 51480675 OV90_OVARY 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LRGUK p.H796Q 7 133948637 133948637 OV90_OVARY 37 Missense_Mutation SNP C G uc003vrm.1 Hybrid_Cap... view
MAF 16 79628537 79628537 OV90_OVARY 37 Intron Del T - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAMDC4 p.D71E 9 139747795 139747795 OV90_OVARY 37 Missense_Mutation SNP C A uc004cjs.2 MAMDC4_uc011mej... Hybrid_Cap... view
MAML1 p.R710Q 5 179200956 179200956 OV90_OVARY 37 Missense_Mutation SNP G A uc003mkm.2 MAML1_uc003mkn.... Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 OV90_OVARY 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP2K6 17 67516651 67516651 OV90_OVARY 37 Intron SNP A G uc002jij.2 MAP2K6_uc002jii... Hybrid_Cap... view
MAP3K1 p.T949del 5 56177849 56177851 OV90_OVARY 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 OV90_OVARY 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAPKBP1 15 42111746 42111746 OV90_OVARY 37 Intron Del G - uc001zok.3 MAPKBP1_uc001zo... Hybrid_Cap...
MELK p.L458F 9 36665542 36665542 OV90_OVARY 37 Missense_Mutation SNP C T uc003zzn.2 MELK_uc011lpm.1... Hybrid_Cap... view
MLKL p.M122V 16 74729292 74729292 OV90_OVARY 37 Missense_Mutation SNP T C uc002fdb.2 MLKL_uc002fdc.2... Hybrid_Cap... view
MLLT6 17 36881873 36881873 OV90_OVARY 37 3'UTR Del C - uc002hqi.3 MLLT6_uc002hqk.... Hybrid_Cap...
MMP1 p.G221S 11 102666303 102666303 OV90_OVARY 37 Missense_Mutation SNP C T uc001phi.2 MMP1_uc010ruv.1... Hybrid_Cap... view
MSH3 p.PPA66del 5 79950742 79950750 OV90_OVARY 37 In_Frame_Del Del CCCCC... - rs60484572;rs1047489 uc003kgz.2 DHFR_uc011ctl.1... Hybrid_Cap...
MYH11 p.D1316D 16 15818781 15818781 OV90_OVARY 37 Silent SNP G A uc002ddx.2 MYH11_uc002ddv.... Hybrid_Cap... view
MYLK p.M1513V 3 123366153 123366153 OV90_OVARY 37 Missense_Mutation SNP T C uc003ego.2 MYLK_uc010hrr.2... Hybrid_Cap... view
NCAM1 11 112832307 112832308 OV90_OVARY 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 OV90_OVARY 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 OV90_OVARY 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NFIA 1 61921185 61921186 OV90_OVARY 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NFKB1 p.D917_splice 4 103534740 103534741 OV90_OVARY 37 Splice_Site_Ins Ins - A rs35795162 uc011cep.1 NFKB1_uc011ceq.... Hybrid_Cap...
NOVA1 14 26939509 26939509 OV90_OVARY 37 Intron SNP C T uc001wpy.2 NOVA1_uc001wpz.... Hybrid_Cap... view
NPM1 5 170837734 170837734 OV90_OVARY 37 3'UTR Del T - uc011dex.1 NPM1_uc003mbi.2... Hybrid_Cap...
NPR1 1 153665919 153665920 OV90_OVARY 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 OV90_OVARY 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NUP153 p.G162E 6 17675851 17675851 OV90_OVARY 37 Missense_Mutation SNP C T uc011dje.1 NUP153_uc003ncd... Hybrid_Cap... view
NUP210 p.A684T 3 13401874 13401874 OV90_OVARY 37 Missense_Mutation SNP C T uc003bxv.1 NUP210_uc003bxx... Hybrid_Cap... view
PAPPA 9 119158923 119158923 OV90_OVARY 37 3'UTR SNP C T uc004bjn.2 PAPPA_uc011lxq.... Hybrid_Cap... view
PAX3 2 223158653 223158653 OV90_OVARY 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PDE4DIP p.R1852Q 1 144866687 144866687 OV90_OVARY 37 Missense_Mutation SNP C T uc001elw.3 NBPF10_uc009wir... Hybrid_Cap... view
PHIP 6 79650265 79650266 OV90_OVARY 37 3'UTR Ins - TTTT rs70977753;rs13191571 uc003pir.2 PHIP_uc003piq.2... Hybrid_Cap...
PIK3C2G p.P129del 12 18435399 18435401 OV90_OVARY 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PIK3R1 5 67584340 67584341 OV90_OVARY 37 Intron Ins - CGAGC rs72310992 uc003jva.2 PIK3R1_uc003jvb... Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 OV90_OVARY 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PRKG1 10 54053913 54053914 OV90_OVARY 37 3'UTR Ins - G rs35902208 uc001jjo.2 PRKG1_uc001jjm.... Hybrid_Cap...
PTK7 p.R933C 6 43126606 43126606 OV90_OVARY 37 Missense_Mutation SNP C T uc011dve.1 PTK7_uc003oub.1... Hybrid_Cap... view
RASGRF1 15 79277150 79277151 OV90_OVARY 37 Intron Ins - C rs67045840;rs77640668 uc002beq.2 RASGRF1_uc002be... Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 OV90_OVARY 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
REL 2 61149779 61149779 OV90_OVARY 37 3'UTR SNP C T uc002sam.1 REL_uc002san.1_... Hybrid_Cap... view
RPS6KA5 14 91360733 91360734 OV90_OVARY 37 Intron Ins - T rs77438853 uc001xys.2 RPS6KA5_uc010tw... Hybrid_Cap...
RPS6KL1 14 75373626 75373627 OV90_OVARY 37 3'UTR Ins - TGAT uc001xqx.1 RPS6KL1_uc001xq... Hybrid_Cap...
SCD5 4 83552278 83552279 OV90_OVARY 37 3'UTR Ins - A rs72177305 uc003hna.2 Hybrid_Cap...
SEPT9 17 75494787 75494788 OV90_OVARY 37 3'UTR Ins - C rs5822173 uc002jts.3 SEPT9_uc010wtk.... Hybrid_Cap...
SIK2 p.P705L 11 111593447 111593447 OV90_OVARY 37 Missense_Mutation SNP C T uc001plt.2 Hybrid_Cap... view
SMAD4 p.R445* 18 48603032 48603032 OV90_OVARY 37 Nonsense_Mutation SNP C T uc010xdp.1 SMAD4_uc002lfb.... Hybrid_Cap... view
SORL1 11 121500401 121500402 OV90_OVARY 37 3'UTR Del AA - uc001pxx.2 SORL1_uc010rzp.... Hybrid_Cap...
SPEN p.M937I 1 16255546 16255546 OV90_OVARY 37 Missense_Mutation SNP G C uc001axk.1 SPEN_uc010obp.1... Hybrid_Cap... view
STK31 7 23872024 23872025 OV90_OVARY 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TEC 4 48139307 48139310 OV90_OVARY 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
THRAP3 p.K688R 1 36759484 36759484 OV90_OVARY 37 Missense_Mutation SNP A G uc001cae.3 THRAP3_uc001caf... Hybrid_Cap... view
TLK1 2 171850178 171850179 OV90_OVARY 37 3'UTR Ins - AA rs71008739 uc002ugo.2 TLK1_uc002ugn.2... Hybrid_Cap...
TNKS2 p.N118S 10 93572893 93572893 OV90_OVARY 37 Missense_Mutation SNP A G rs61756248 uc001khp.2 Hybrid_Cap... view
TP53 p.S215R 17 7578206 7578206 OV90_OVARY 37 Missense_Mutation SNP T G uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TRIM33 1 114940215 114940216 OV90_OVARY 37 3'UTR Ins - G rs68133208 uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TRPS1 8 116635872 116635873 OV90_OVARY 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TTN 2 179391639 179391640 OV90_OVARY 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.R32023Q 2 179397570 179397570 OV90_OVARY 37 Missense_Mutation SNP C T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 OV90_OVARY 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...