Annotation Summary for Cell Line: OVCAR-4  

Cell line primary name: OVCAR-4
Cell line aliases:
Gender: F
Site Primary: ovary
Histology: carcinoma
Hist Subtype1: NS
Notes:
Source: NCI/DCTD
Expression arrays: BRAKE_p_NCLE_RNA2_HG-U133_Plus_2_A11_241062
SNP arrays: ARLES_p_NCLE_DNAAffy2_S_GenomeWideSNP_6_A02_256004
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in OVCAR-4

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 OVCAR4_OVARY 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ACVRL1 p.V194L 12 52307812 52307812 OVCAR4_OVARY 37 Missense_Mutation SNP G C uc001rzj.2 ACVRL1_uc001rzk... Hybrid_Cap... view
ACVRL1 p.I276L 12 52309062 52309062 OVCAR4_OVARY 37 Missense_Mutation SNP A C uc001rzj.2 ACVRL1_uc001rzk... Hybrid_Cap... view
ADAM28 8 24211994 24211997 OVCAR4_OVARY 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADCK1 14 78390632 78390637 OVCAR4_OVARY 37 Intron Del AAACT... - rs78274857;rs74969652 uc001xui.2 ADCK1_uc010tvo.... Hybrid_Cap...
ADCK2 7 140373061 140373061 OVCAR4_OVARY 37 5'UTR SNP A G uc003vvy.1 ADCK2_uc003vvz.... Hybrid_Cap... view
AKAP12 p.1531_1532insE 6 151674116 151674117 OVCAR4_OVARY 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP9 7 91670319 91670319 OVCAR4_OVARY 37 Intron Del T - uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ALDH7A1 5 125930950 125930950 OVCAR4_OVARY 37 5'UTR SNP C T uc003ktx.2 ALDH7A1_uc003kt... Hybrid_Cap... view
ALPK1 4 113347609 113347610 OVCAR4_OVARY 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
ARHGEF7 13 111944877 111944877 OVCAR4_OVARY 37 3'UTR SNP G A uc001vrs.2 ARHGEF7_uc001vr... Hybrid_Cap... view
ARNT p.Q250K 1 150807069 150807069 OVCAR4_OVARY 37 Missense_Mutation SNP G T uc001evr.1 ARNT_uc001evs.1... Hybrid_Cap... view
ATM p.N230T 11 108115541 108115541 OVCAR4_OVARY 37 Missense_Mutation SNP A C uc001pkb.1 ATM_uc009yxr.1_... Hybrid_Cap... view
BCR 22 23631813 23631814 OVCAR4_OVARY 37 Intron Ins - C rs66503844 uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BLK p.R131G 8 11407690 11407690 OVCAR4_OVARY 37 Missense_Mutation SNP C G rs73663163 uc003wty.2 BLK_uc003wtz.2_... Hybrid_Cap... view
CAMKV p.E440D 3 49896937 49896937 OVCAR4_OVARY 37 Missense_Mutation SNP C A uc003cxt.1 TRAIP_uc003cxs.... Hybrid_Cap... view
CDK11B 1 1654066 1654068 OVCAR4_OVARY 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CDK20 p.L67R 9 90586240 90586240 OVCAR4_OVARY 37 Missense_Mutation SNP A C uc004apr.2 CDK20_uc004aps.... Hybrid_Cap... view
CDKN2A p.S21T 9 21994393 21994393 OVCAR4_OVARY 37 Missense_Mutation SNP A T uc003zpl.2 MTAP_uc003zpi.1... Hybrid_Cap... view
CHEK1 11 125525382 125525382 OVCAR4_OVARY 37 3'UTR SNP A C uc009zbo.2 CHEK1_uc010sbh.... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 OVCAR4_OVARY 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CREB3L2 p.T100del 7 137612914 137612916 OVCAR4_OVARY 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CSF1R 5 149433400 149433401 OVCAR4_OVARY 37 3'UTR Ins - C rs66970099;rs78449650 uc003lrl.2 CSF1R_uc011dcd.... Hybrid_Cap...
CTBP2 p.Q175fs 10 126715804 126715805 OVCAR4_OVARY 37 Frame_Shift_Del Del CT - uc001lie.3 CTBP2_uc009yak.... Hybrid_Cap...
CXCL12 10 44873992 44873993 OVCAR4_OVARY 37 Intron Ins - CT rs117617571 uc001jbh.2 CXCL12_uc001jbf... Hybrid_Cap...
CYP3A4 7 99355609 99355609 OVCAR4_OVARY 37 3'UTR SNP T G uc003urv.1 CYP3A4_uc003urw... Hybrid_Cap... view
DNAH8 6 38952247 38952250 OVCAR4_OVARY 37 Intron Del CACA - uc003ooe.1 DNAH8_uc003oog.... Hybrid_Cap...
EDN1 6 12290729 12290729 OVCAR4_OVARY 37 5'UTR Del A - uc003nae.3 EDN1_uc010jpb.2... Hybrid_Cap...
EIF4A2 p.P233fs 3 186504359 186504374 OVCAR4_OVARY 37 Frame_Shift_Del Del AATTC... - uc003fqu.2 EIF4A2_uc003fqs... Hybrid_Cap...
EIF4G1 3 184038407 184038407 OVCAR4_OVARY 37 Intron SNP T G uc010hxx.2 EIF4G1_uc003fno... Hybrid_Cap... view
EP300 p.E999Q 22 41548014 41548014 OVCAR4_OVARY 37 Missense_Mutation SNP G C uc003azl.3 Hybrid_Cap... view
EPHA6 3 97367230 97367231 OVCAR4_OVARY 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
EPHB4 p.E43V 7 100421549 100421549 OVCAR4_OVARY 37 Missense_Mutation SNP T A uc003uwn.1 EPHB4_uc003uwm.... Hybrid_Cap... view
EPO 7 100320772 100320772 OVCAR4_OVARY 37 3'UTR SNP T C uc003uwi.2 EPO_uc011kkc.1_... Hybrid_Cap... view
ERCC6 p.E382V 10 50732331 50732331 OVCAR4_OVARY 37 Missense_Mutation SNP T A rs56089364 uc001jhs.3 PGBD3_uc001jht.... Hybrid_Cap... view
ETV1 7 14028708 14028708 OVCAR4_OVARY 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
EXT1 8 118811807 118811807 OVCAR4_OVARY 37 3'UTR Del T - uc003yok.1 Hybrid_Cap...
F8 p.N1192K X 154158489 154158489 OVCAR4_OVARY 37 Missense_Mutation SNP G T uc004fmt.2 Hybrid_Cap... view
FGFR1OP p.E210K 6 167435945 167435945 OVCAR4_OVARY 37 Missense_Mutation SNP G A uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap... view
FGFR3 4 1809128 1809129 OVCAR4_OVARY 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLI1 p.L29L 11 128628078 128628078 OVCAR4_OVARY 37 Silent SNP C A uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap... view
FLI1 11 128638217 128638217 OVCAR4_OVARY 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLT4 p.C111R 5 180057624 180057624 OVCAR4_OVARY 37 Missense_Mutation SNP A G uc003mlz.3 FLT4_uc003mma.3... Hybrid_Cap... view
FN1 2 216244182 216244185 OVCAR4_OVARY 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
FRAT1 10 99080247 99080247 OVCAR4_OVARY 37 3'UTR Del T - uc001knc.1 Hybrid_Cap...
FZD1 p.93_94insP 7 90894459 90894460 OVCAR4_OVARY 37 In_Frame_Ins Ins - CCG uc003ula.2 Hybrid_Cap...
GPR112 p.D2657del X 135474445 135474447 OVCAR4_OVARY 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 OVCAR4_OVARY 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 OVCAR4_OVARY 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HIF1A 14 62213929 62213930 OVCAR4_OVARY 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HNF1A 12 121434630 121434631 OVCAR4_OVARY 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
HSPA1B 6 31797769 31797770 OVCAR4_OVARY 37 3'UTR Ins - AAGTT rs67206812 uc003nxk.2 Hybrid_Cap...
ICK p.PSPL369del 6 52878495 52878506 OVCAR4_OVARY 37 In_Frame_Del Del GCAAC... - uc003pbh.2 ICK_uc003pbi.2_... Hybrid_Cap...
IKZF1 7 50468454 50468455 OVCAR4_OVARY 37 3'UTR Ins - T uc003tow.3 IKZF1_uc003tox.... Hybrid_Cap...
ILK 11 6630029 6630029 OVCAR4_OVARY 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITGB1 10 33197131 33197134 OVCAR4_OVARY 37 Intron Del CTTT - rs116966876 uc001iwq.3 ITGB1_uc001iwp.... Hybrid_Cap...
KALRN p.H621P 3 124103789 124103789 OVCAR4_OVARY 37 Missense_Mutation SNP A C uc003ehg.2 KALRN_uc010hrv.... Hybrid_Cap... view
KLK7 19 51480672 51480675 OVCAR4_OVARY 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LIFR 5 38481534 38481534 OVCAR4_OVARY 37 3'UTR SNP A C uc010ive.1 LIFR_uc003jli.2... Hybrid_Cap... view
LRP1 p.V2520G 12 57586962 57586962 OVCAR4_OVARY 37 Missense_Mutation SNP T G uc001snd.2 MIR1228_hsa-mir... Hybrid_Cap... view
LRRK2 p.R2394S 12 40758644 40758644 OVCAR4_OVARY 37 Missense_Mutation SNP G C uc001rmg.3 LRRK2_uc009zjw.... Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 OVCAR4_OVARY 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 OVCAR4_OVARY 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 OVCAR4_OVARY 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAPKAPK3 3 50685575 50685575 OVCAR4_OVARY 37 3'UTR Del A - rs76026164 uc003day.1 MAPKAPK3_uc003d... Hybrid_Cap...
MAST1 19 12969701 12969701 OVCAR4_OVARY 37 Intron SNP C T uc002mvm.2 MAST1_uc002mvk.... Hybrid_Cap... view
MCM3AP p.S1076Y 21 47685242 47685242 OVCAR4_OVARY 37 Missense_Mutation SNP G T uc002zir.1 MCM3AP_uc002ziq... Hybrid_Cap... view
MECOM p.G1143A 3 168806945 168806945 OVCAR4_OVARY 37 Missense_Mutation SNP C G uc011bpj.1 MECOM_uc010hwk.... Hybrid_Cap... view
MGA p.D2682N 15 42058324 42058324 OVCAR4_OVARY 37 Missense_Mutation SNP G A uc010ucy.1 MGA_uc010ucz.1_... Hybrid_Cap... view
MKL1 p.P779P 22 40807853 40807853 OVCAR4_OVARY 37 Silent SNP C T uc003ayv.1 MKL1_uc003ayw.1... Hybrid_Cap... view
MMP2 16 55539486 55539486 OVCAR4_OVARY 37 3'UTR SNP T A rs55926431 uc002ehz.3 MMP2_uc010vhd.1... Hybrid_Cap... view
MSH3 p.PPA66del 5 79950742 79950750 OVCAR4_OVARY 37 In_Frame_Del Del CCCCC... - rs60484572;rs1047489 uc003kgz.2 DHFR_uc011ctl.1... Hybrid_Cap...
NCAM1 11 112832307 112832308 OVCAR4_OVARY 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 OVCAR4_OVARY 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAPD3 p.E816K 11 134054537 134054537 OVCAR4_OVARY 37 Missense_Mutation SNP C T uc001qhd.1 NCAPD3_uc010scm... Hybrid_Cap... view
NCOA3 p.Q1276del 20 46279837 46279839 OVCAR4_OVARY 37 In_Frame_Del Del CAG - rs2664555 uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 OVCAR4_OVARY 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NLRP3 1 247611982 247611982 OVCAR4_OVARY 37 3'UTR Del C - uc001icr.2 NLRP3_uc001ics.... Hybrid_Cap...
NPR1 1 153665919 153665920 OVCAR4_OVARY 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 OVCAR4_OVARY 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
PAX3 2 223158653 223158653 OVCAR4_OVARY 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PDGFRA 4 55131002 55131002 OVCAR4_OVARY 37 Intron Del A - uc003han.3 PDGFRA_uc003haa... Hybrid_Cap...
PGGT1B 5 114548071 114548072 OVCAR4_OVARY 37 3'UTR Ins - C uc003kqw.3 PGGT1B_uc003kqx... Hybrid_Cap...
PGR 11 100933598 100933599 OVCAR4_OVARY 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PHKG2 p.R44Q 16 30762462 30762462 OVCAR4_OVARY 37 Missense_Mutation SNP G A uc002dzi.1 PHKG2_uc002dzj.... Hybrid_Cap... view
PRKACG p.P317S 9 71628060 71628060 OVCAR4_OVARY 37 Missense_Mutation SNP G A uc004agy.2 Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 OVCAR4_OVARY 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PRKG2 p.L534V 4 82058581 82058581 OVCAR4_OVARY 37 Missense_Mutation SNP A C uc003hmh.2 PRKG2_uc011ccf.... Hybrid_Cap... view
RASGRF1 15 79277150 79277151 OVCAR4_OVARY 37 Intron Ins - C rs67045840;rs77640668 uc002beq.2 RASGRF1_uc002be... Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 OVCAR4_OVARY 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RELA 11 65422524 65422524 OVCAR4_OVARY 37 Intron SNP C T uc010ron.1 RELA_uc001ofg.2... Hybrid_Cap... view
SGK494 p.R160G 17 26939705 26939705 OVCAR4_OVARY 37 Missense_Mutation SNP G C uc002hbr.1 SGK494_uc010waq... Hybrid_Cap... view
SLC14A1 18 43310166 43310166 OVCAR4_OVARY 37 Intron SNP A G uc010dnk.2 SLC14A1_uc010xc... Hybrid_Cap... view
TAOK3 12 118588761 118588762 OVCAR4_OVARY 37 3'UTR Ins - T rs116872184 uc001twx.2 TAOK3_uc001twv.... Hybrid_Cap...
TEC 4 48139307 48139310 OVCAR4_OVARY 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TGFB2 1 218519928 218519929 OVCAR4_OVARY 37 5'UTR Ins - AAAC uc001hln.2 TGFB2_uc001hll.... Hybrid_Cap...
TMEM123 11 102269398 102269398 OVCAR4_OVARY 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TNKS2 10 93622889 93622889 OVCAR4_OVARY 37 3'UTR SNP G A uc001khp.2 Hybrid_Cap... view
TNRC6B p.Q1328del 22 40697177 40697179 OVCAR4_OVARY 37 In_Frame_Del Del GCA - rs114291931 uc011aor.1 TNRC6B_uc003aym... Hybrid_Cap...
TP53 p.L130V 17 7578542 7578542 OVCAR4_OVARY 37 Missense_Mutation SNP G C uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TRIM33 1 114940215 114940216 OVCAR4_OVARY 37 3'UTR Ins - G rs68133208 uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TTBK1 p.E771del 6 43250726 43250728 OVCAR4_OVARY 37 In_Frame_Del Del GAA - uc003ouq.1 Hybrid_Cap...
VAV1 p.Q217R 19 6822521 6822521 OVCAR4_OVARY 37 Missense_Mutation SNP A G uc002mfu.1 VAV1_uc010xjh.1... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 OVCAR4_OVARY 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
WHSC1L1 8 38175273 38175273 OVCAR4_OVARY 37 Intron SNP C G rs75965102 uc003xli.2 WHSC1L1_uc011lb... Hybrid_Cap... view
ZAP70 2 98351655 98351655 OVCAR4_OVARY 37 Intron Del G - uc002syd.1 ZAP70_uc010yvf.... Hybrid_Cap...
ZNF521 p.K1045N 18 22804747 22804747 OVCAR4_OVARY 37 Missense_Mutation SNP C G uc002kvk.2 ZNF521_uc010xbe... Hybrid_Cap... view