Annotation Summary for Cell Line: OVCAR-8  

Cell line primary name: OVCAR-8
Cell line aliases:
Gender: F
Site Primary: ovary
Histology: carcinoma
Hist Subtype1: NS
Notes:
Source: NCI/DCTD
Expression arrays: CRAZY_p_NCLE_RNA10_HG-U133_Plus_2_G07_569544
SNP arrays: ARLES_p_NCLE_DNAAffy2_S_GenomeWideSNP_6_C07_256062
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in OVCAR-8

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 OVCAR8_OVARY 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ACACA 17 35766564 35766564 OVCAR8_OVARY 37 5'UTR Del A - uc002hno.2 ACACA_uc002hnn.... Hybrid_Cap...
ACACB p.Y877* 12 109637210 109637210 OVCAR8_OVARY 37 Nonsense_Mutation SNP C A uc001tob.2 ACACB_uc001toc.... Hybrid_Cap... view
ADAM17 2 9630245 9630245 OVCAR8_OVARY 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM17 p.P556L 2 9637359 9637359 OVCAR8_OVARY 37 Missense_Mutation SNP G A uc002qzu.2 ADAM17_uc010ewy... Hybrid_Cap... view
ADAM28 8 24211994 24211997 OVCAR8_OVARY 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 OVCAR8_OVARY 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ANAPC5 12 121790193 121790195 OVCAR8_OVARY 37 5'UTR Del CAC - uc001uag.2 ANAPC5_uc001uah... Hybrid_Cap...
ARFGEF1 8 68117149 68117149 OVCAR8_OVARY 37 Intron SNP T C uc003xxo.1 ARFGEF1_uc003xx... Hybrid_Cap... view
ASPH p.A264_splice 8 62550924 62550925 OVCAR8_OVARY 37 Splice_Site_Ins Ins - A rs5891816 uc003xuj.2 ASPH_uc011leg.1... Hybrid_Cap...
ATM p.V613L 11 108123578 108123578 OVCAR8_OVARY 37 Missense_Mutation SNP G T uc001pkb.1 ATM_uc009yxr.1_... Hybrid_Cap... view
AXL p.H292Q 19 41743941 41743941 OVCAR8_OVARY 37 Missense_Mutation SNP T A uc010ehj.2 CYP2F1_uc010xvw... Hybrid_Cap... view
BCL3 19 45262965 45262966 OVCAR8_OVARY 37 3'UTR Del CC - uc010xxe.1 Hybrid_Cap...
BCR 22 23631813 23631814 OVCAR8_OVARY 37 Intron Ins - C rs66503844 uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BCR 22 23632777 23632778 OVCAR8_OVARY 37 Intron Ins - T uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BMP2K p.P538R 4 79793772 79793772 OVCAR8_OVARY 37 Missense_Mutation SNP C G uc003hlk.2 BMP2K_uc003hlj.... Hybrid_Cap... view
CAD p.A2201T 2 27466309 27466309 OVCAR8_OVARY 37 Missense_Mutation SNP G A uc002rji.2 CAD_uc010eyw.2_... Hybrid_Cap... view
CARD10 p.KE272del 22 37906309 37906314 OVCAR8_OVARY 37 In_Frame_Del Del CTCCT... - uc003asx.1 CARD10_uc003ast... Hybrid_Cap...
CDK17 12 96674483 96674483 OVCAR8_OVARY 37 Intron SNP T C uc001tep.1 CDK17_uc009ztk.... Hybrid_Cap... view
CHD1 p.P1684del 5 98192165 98192167 OVCAR8_OVARY 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CHIC2 4 54876194 54876194 OVCAR8_OVARY 37 3'UTR SNP G A uc003haj.1 PDGFRA_uc003haa... Hybrid_Cap... view
CLTC p.Q177_splice 17 57725028 57725028 OVCAR8_OVARY 37 Splice_Site_SNP SNP G T uc002ixr.1 CLTC_uc002ixp.2... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 OVCAR8_OVARY 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CREB3L2 p.T100del 7 137612914 137612916 OVCAR8_OVARY 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CREBBP p.S893* 16 3820773 3820773 OVCAR8_OVARY 37 Nonsense_Mutation SNP G T uc002cvv.2 CREBBP_uc002cvw... Hybrid_Cap... view
CTNNB1 p.Q26R 3 41266080 41266080 OVCAR8_OVARY 37 Missense_Mutation SNP A G uc010hia.1 CTNNB1_uc003ckp... Hybrid_Cap... view
DCLK3 3 36756711 36756711 OVCAR8_OVARY 37 3'UTR SNP T C uc003cgi.2 Hybrid_Cap... view
DIP2C p.P249T 10 461823 461823 OVCAR8_OVARY 37 Missense_Mutation SNP G T uc001ifp.2 DIP2C_uc009xhj.... Hybrid_Cap... view
DLL1 p.G185R 6 170597444 170597444 OVCAR8_OVARY 37 Missense_Mutation SNP C T uc003qxm.2 DLL1_uc011ehc.1... Hybrid_Cap... view
DNAH8 p.V1651G 6 38820993 38820993 OVCAR8_OVARY 37 Missense_Mutation SNP T G uc003ooe.1 Hybrid_Cap... view
DVL1 p.A317A 1 1275151 1275151 OVCAR8_OVARY 37 Silent SNP G A uc001aer.3 DVL1_uc002quu.2... Hybrid_Cap... view
EDN1 6 12290729 12290729 OVCAR8_OVARY 37 5'UTR Del A - uc003nae.3 EDN1_uc010jpb.2... Hybrid_Cap...
EML4 2 42513400 42513400 OVCAR8_OVARY 37 Intron SNP T A uc002rsi.2 EML4_uc010fap.2... Hybrid_Cap... view
EP300 p.D1729fs 22 41572902 41572902 OVCAR8_OVARY 37 Frame_Shift_Del Del T - uc003azl.3 Hybrid_Cap...
EPHA6 3 97367230 97367231 OVCAR8_OVARY 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
ERBB2 p.G776V 17 37880998 37880998 OVCAR8_OVARY 37 Missense_Mutation SNP G T uc002hso.2 ERBB2_uc002hsm.... Hybrid_Cap... view
ETV1 7 14028708 14028708 OVCAR8_OVARY 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
EXT1 8 118811807 118811807 OVCAR8_OVARY 37 3'UTR Del T - uc003yok.1 Hybrid_Cap...
FGFR1OP 6 167453519 167453520 OVCAR8_OVARY 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 OVCAR8_OVARY 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLI1 11 128638217 128638217 OVCAR8_OVARY 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLNA p.P2350A X 153579385 153579385 OVCAR8_OVARY 37 Missense_Mutation SNP G C uc004fkk.2 FLNA_uc004fki.2... Hybrid_Cap... view
GPR112 p.D2657del X 135474445 135474447 OVCAR8_OVARY 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 OVCAR8_OVARY 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 OVCAR8_OVARY 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HDAC2 p.81_82insS 6 114292109 114292110 OVCAR8_OVARY 37 In_Frame_Ins Ins - CTG uc003pwd.1 HDAC2_uc003pwc.... Hybrid_Cap...
HDAC6 X 48664724 48664724 OVCAR8_OVARY 37 Intron SNP T A uc011mmi.1 HDAC6_uc004dkr.... Hybrid_Cap... view
HERC2 p.I431K 15 28514548 28514548 OVCAR8_OVARY 37 Missense_Mutation SNP A T uc001zbj.2 HERC2_uc001zbl.... Hybrid_Cap... view
HIF1A 14 62213929 62213930 OVCAR8_OVARY 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HNF1A 12 121434630 121434631 OVCAR8_OVARY 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
HSP90B1 12 104341645 104341648 OVCAR8_OVARY 37 3'UTR Del ACTG - rs2307842 uc001tkb.1 HSP90B1_uc010sw... Hybrid_Cap...
IGF1R 15 99192755 99192761 OVCAR8_OVARY 37 5'UTR Del TTTTT... - uc002bul.2 IGF1R_uc010urq.... Hybrid_Cap...
ILK 11 6630029 6630029 OVCAR8_OVARY 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 OVCAR8_OVARY 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
JARID2 6 15246671 15246671 OVCAR8_OVARY 37 5'UTR SNP A C uc003nbj.2 JARID2_uc011diu... Hybrid_Cap... view
KALRN p.K1791E 3 124351461 124351461 OVCAR8_OVARY 37 Missense_Mutation SNP A G uc003ehg.2 KALRN_uc003ehi.... Hybrid_Cap... view
KRAS p.P121H 12 25378636 25378636 OVCAR8_OVARY 37 Missense_Mutation SNP G T uc001rgp.1 KRAS_uc001rgq.1... Hybrid_Cap... view
LAMA1 p.T173P 18 7050764 7050764 OVCAR8_OVARY 37 Missense_Mutation SNP T G uc002knm.2 LAMA1_uc010wzj.... Hybrid_Cap... view
MAMDC4 p.T168fs 9 139748277 139748296 OVCAR8_OVARY 37 Frame_Shift_Del Del CCCTG... - uc004cjs.2 MAMDC4_uc011mej... Hybrid_Cap...
MAML1 p.Q617L 5 179195969 179195969 OVCAR8_OVARY 37 Missense_Mutation SNP A T uc003mkm.2 MAML1_uc003mkn.... Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 OVCAR8_OVARY 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 OVCAR8_OVARY 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 OVCAR8_OVARY 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAP4K5 p.R552Q 14 50906781 50906781 OVCAR8_OVARY 37 Missense_Mutation SNP C T rs55997280 uc001wya.2 MAP4K5_uc001wyb... Hybrid_Cap... view
MAPKAPK3 3 50685575 50685575 OVCAR8_OVARY 37 3'UTR Del A - rs76026164 uc003day.1 MAPKAPK3_uc003d... Hybrid_Cap...
MCF2 p.K796Q X 138678827 138678827 OVCAR8_OVARY 37 Missense_Mutation SNP T G uc011mwo.1 MCF2_uc004fau.2... Hybrid_Cap... view
MMP1 11 102661002 102661002 OVCAR8_OVARY 37 3'UTR SNP T C rs5031038 uc001phi.2 MMP1_uc010ruv.1... Hybrid_Cap... view
MYLK p.G902V 3 123419610 123419610 OVCAR8_OVARY 37 Missense_Mutation SNP C A uc003ego.2 MYLK_uc011bjw.1... Hybrid_Cap... view
MYST4 p.E1104del 10 76781906 76781908 OVCAR8_OVARY 37 In_Frame_Del Del GAA - rs79644703 uc001jwn.1 MYST4_uc001jwm.... Hybrid_Cap...
NAV3 p.L2304M 12 78598790 78598790 OVCAR8_OVARY 37 Missense_Mutation SNP C A uc001syp.2 NAV3_uc001syo.2... Hybrid_Cap... view
NCAM1 11 112832307 112832308 OVCAR8_OVARY 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 OVCAR8_OVARY 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA2 p.I162M 8 71082492 71082492 OVCAR8_OVARY 37 Missense_Mutation SNP G C uc003xyn.1 Hybrid_Cap... view
NCOA3 p.Q1276del 20 46279837 46279839 OVCAR8_OVARY 37 In_Frame_Del Del CAG - rs2664555 uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NCOA3 20 46282339 46282340 OVCAR8_OVARY 37 3'UTR Ins - AT uc002xtk.2 NCOA3_uc002xtl.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 OVCAR8_OVARY 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NOTCH1 p.P1486L 9 139399891 139399891 OVCAR8_OVARY 37 Missense_Mutation SNP G A uc004chz.2 NOTCH1_uc004cia... Hybrid_Cap... view
NOTCH4 p.15_16LL>L 6 32191659 32191661 OVCAR8_OVARY 37 In_Frame_Del Del AGC - uc003obb.2 NOTCH4_uc011dpu... Hybrid_Cap...
NPR1 1 153665919 153665920 OVCAR8_OVARY 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 OVCAR8_OVARY 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NUP214 p.N586T 9 134020129 134020129 OVCAR8_OVARY 37 Missense_Mutation SNP A C uc004cag.2 NUP214_uc004cah... Hybrid_Cap... view
PAK6 15 40509659 40509659 OVCAR8_OVARY 37 5'UTR SNP C T uc010bbl.2 BUB1B_uc001zkx.... Hybrid_Cap... view
PAX3 2 223158653 223158653 OVCAR8_OVARY 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PBK 8 27667649 27667649 OVCAR8_OVARY 37 3'UTR SNP C T rs117291578 uc011lap.1 ESCO2_uc010luy.... Hybrid_Cap... view
PDE4DIP p.Q1665fs 1 144873963 144873963 OVCAR8_OVARY 37 Frame_Shift_Del Del T - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDE4DIP p.V486fs 1 144917828 144917828 OVCAR8_OVARY 37 Frame_Shift_Del Del A - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDGFRA 4 55131002 55131002 OVCAR8_OVARY 37 Intron Del A - uc003han.3 PDGFRA_uc003haa... Hybrid_Cap...
PHIP 6 79650265 79650266 OVCAR8_OVARY 37 3'UTR Ins - TTTT rs70977753;rs13191571 uc003pir.2 PHIP_uc003piq.2... Hybrid_Cap...
PICALM p.G568S 11 85692249 85692249 OVCAR8_OVARY 37 Missense_Mutation SNP C T uc001pbm.2 PICALM_uc001pbl... Hybrid_Cap... view
PIK3C2G p.P129del 12 18435399 18435401 OVCAR8_OVARY 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PIK3C2G 12 18800990 18800990 OVCAR8_OVARY 37 3'UTR Del A - rs16914368 uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PIP5K1B p.D80N 9 71491630 71491630 OVCAR8_OVARY 37 Missense_Mutation SNP G A uc004agu.2 PIP5K1B_uc011lr... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 OVCAR8_OVARY 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PTK7 6 43127506 43127506 OVCAR8_OVARY 37 Intron SNP G C uc011dve.1 PTK7_uc003oub.1... Hybrid_Cap... view
PTPRD 9 8733894 8733894 OVCAR8_OVARY 37 5'UTR SNP G A uc003zkk.2 PTPRD_uc003zkp.... Hybrid_Cap... view
RAPGEF2 4 160189197 160189198 OVCAR8_OVARY 37 5'UTR Ins - C uc003iqg.3 Hybrid_Cap...
RIPK4 p.K51T 21 43187050 43187050 OVCAR8_OVARY 37 Missense_Mutation SNP T G uc002yzn.1 Hybrid_Cap... view
SETDB1 1 150917624 150917624 OVCAR8_OVARY 37 Intron Del G - uc001evu.2 SETDB1_uc009wmf... Hybrid_Cap...
SLC6A8 X 152957656 152957657 OVCAR8_OVARY 37 Intron Ins - A uc004fib.3 SLC6A8_uc004fic... Hybrid_Cap...
STAT5A 17 40462797 40462800 OVCAR8_OVARY 37 3'UTR Del TGTG - uc002hzj.1 STAT5A_uc010cya... Hybrid_Cap...
TP53 p.Y126_splice 17 7578555 7578555 OVCAR8_OVARY 37 Splice_Site_SNP SNP C T uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TRPS1 8 116635872 116635873 OVCAR8_OVARY 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TTBK2 p.V716L 15 43045298 43045298 OVCAR8_OVARY 37 Missense_Mutation SNP C A uc001zqo.2 TTBK2_uc010bcy.... Hybrid_Cap... view
UBR5 p.A823V 8 103323675 103323675 OVCAR8_OVARY 37 Missense_Mutation SNP G A uc003ykr.1 UBR5_uc003yks.1... Hybrid_Cap... view
UNC13C p.L992V 15 54308074 54308074 OVCAR8_OVARY 37 Missense_Mutation SNP T G uc002ack.2 Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 OVCAR8_OVARY 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
XPC p.A193V 3 14208712 14208712 OVCAR8_OVARY 37 Missense_Mutation SNP G A uc011ave.1 XPC_uc011avf.1_... Hybrid_Cap... view
ZAP70 2 98351655 98351655 OVCAR8_OVARY 37 Intron Del G - uc002syd.1 ZAP70_uc010yvf.... Hybrid_Cap...