Annotation Summary for Cell Line: PC-3  

Cell line primary name: PC-3
Cell line aliases:
Gender: M
Site Primary: prostate
Histology: carcinoma
Hist Subtype1: adenocarcinoma
Notes:
Source: ATCC
Expression arrays: PARES_p_NCLE_RNA_Redo_HG-U133_Plus_2_B11_257642
SNP arrays: ARLES_p_NCLE_DNAAffy2_S_GenomeWideSNP_6_C02_256052
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in PC-3

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ABCA3 p.K13N 16 2376429 2376429 PC3_PROSTATE 37 Missense_Mutation SNP C A uc002cpy.1 ABCA3_uc010bsk.... Hybrid_Cap... view
ADAM28 8 24211994 24211997 PC3_PROSTATE 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 PC3_PROSTATE 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP9 7 91670319 91670319 PC3_PROSTATE 37 Intron Del T - uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 PC3_PROSTATE 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ASTN1 p.D1227Y 1 176833626 176833626 PC3_PROSTATE 37 Missense_Mutation SNP C A uc001glc.2 ASTN1_uc001glb.... Hybrid_Cap... view
AURKC 19 57742494 57742507 PC3_PROSTATE 37 5'UTR Del GGACG... - rs67926438;rs112039303;rs59094959 uc002qoe.2 AURKC_uc002qoc.... Hybrid_Cap...
CABC1 1 227171736 227171737 PC3_PROSTATE 37 Intron Ins - T rs1574184 uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CAMK2A 5 149618152 149618152 PC3_PROSTATE 37 Intron SNP G A rs112770824 uc003lrt.2 CAMK2A_uc003lrs... Hybrid_Cap... view
CDK11B p.K127_splice 1 1647893 1647894 PC3_PROSTATE 37 Splice_Site_Ins Ins - TTTCTT rs114930018 uc001agv.1 CDK11B_uc001ags... Hybrid_Cap...
CHIC2 4 54876132 54876132 PC3_PROSTATE 37 3'UTR Del C - rs4437313 uc003haj.1 PDGFRA_uc003haa... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 PC3_PROSTATE 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CREB3L2 p.T100del 7 137612914 137612916 PC3_PROSTATE 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CSF3R 1 36933587 36933587 PC3_PROSTATE 37 Intron SNP T C uc001cax.1 CSF3R_uc001cat.... Hybrid_Cap... view
CTBP2 p.K974fs 10 126678123 126678123 PC3_PROSTATE 37 Frame_Shift_Del Del T - uc001lie.3 CTBP2_uc009yak.... Hybrid_Cap...
CXCL12 10 44873992 44873993 PC3_PROSTATE 37 Intron Ins - CT rs117617571 uc001jbh.2 CXCL12_uc001jbf... Hybrid_Cap...
CXCR2 p.V82I 2 218999768 218999768 PC3_PROSTATE 37 Missense_Mutation SNP G A uc002vgz.1 CXCR2_uc002vha.... Hybrid_Cap... view
CXCR7 2 237490288 237490288 PC3_PROSTATE 37 3'UTR SNP G A uc010fyq.2 CXCR7_uc002vwd.... Hybrid_Cap... view
DAB1 1 57756756 57756756 PC3_PROSTATE 37 5'UTR SNP T C uc001cys.1 DAB1_uc001cyt.1... Hybrid_Cap... view
DACH1 13 72014625 72014626 PC3_PROSTATE 37 3'UTR Ins - T rs117109529 uc010thn.1 DACH1_uc010tho.... Hybrid_Cap...
DAPK2 p.G223R 15 64218285 64218285 PC3_PROSTATE 37 Missense_Mutation SNP C T uc002amr.2 DAPK2_uc010uim.... Hybrid_Cap... view
EIF4E 4 99808137 99808141 PC3_PROSTATE 37 Intron Del TTAAA - uc011ceb.1 EIF4E_uc011cea.... Hybrid_Cap...
EPHA6 3 97367230 97367231 PC3_PROSTATE 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
FGFR1OP 6 167453519 167453520 PC3_PROSTATE 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FLI1 11 128638217 128638217 PC3_PROSTATE 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FN1 2 216244182 216244185 PC3_PROSTATE 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GPR112 p.D2657del X 135474445 135474447 PC3_PROSTATE 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 PC3_PROSTATE 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 PC3_PROSTATE 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HDLBP p.V801A 2 242179225 242179225 PC3_PROSTATE 37 Missense_Mutation SNP A G uc002waz.2 HDLBP_uc002wba.... Hybrid_Cap... view
HIF1A p.Y660N 14 62207788 62207788 PC3_PROSTATE 37 Missense_Mutation SNP T A uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap... view
HNF1A 12 121434630 121434631 PC3_PROSTATE 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
HOXA9 p.R268* 7 27203239 27203239 PC3_PROSTATE 37 Nonsense_Mutation SNP G A uc003syt.2 Hybrid_Cap... view
IL1A p.E133* 2 113537166 113537166 PC3_PROSTATE 37 Nonsense_Mutation SNP C A uc002tig.2 Hybrid_Cap... view
ILK 11 6630029 6630029 PC3_PROSTATE 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
IRAK2 3 10283918 10283918 PC3_PROSTATE 37 3'UTR SNP G A uc003bve.1 Hybrid_Cap... view
ITPR2 p.R470_splice 12 26834804 26834805 PC3_PROSTATE 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KLK7 19 51480672 51480675 PC3_PROSTATE 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LETM2 p.L310F 8 38260127 38260127 PC3_PROSTATE 37 Missense_Mutation SNP C T uc003xlm.1 LETM2_uc011lbn.... Hybrid_Cap... view
MAF 16 79628537 79628537 PC3_PROSTATE 37 Intron Del T - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 PC3_PROSTATE 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 PC3_PROSTATE 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 PC3_PROSTATE 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAP4K1 p.R337R 19 39098806 39098806 PC3_PROSTATE 37 Silent SNP C T uc002oix.1 MAP4K1_uc002oiw... Hybrid_Cap... view
MAPKAPK3 3 50685575 50685575 PC3_PROSTATE 37 3'UTR Del A - rs76026164 uc003day.1 MAPKAPK3_uc003d... Hybrid_Cap...
MAPKBP1 15 42111753 42111754 PC3_PROSTATE 37 Intron Ins - C rs3034891 uc001zok.3 MAPKBP1_uc001zo... Hybrid_Cap...
MCM3APAS 21 47671275 47671276 PC3_PROSTATE 37 3'UTR Ins - AAT rs67797185 uc002zin.2 MCM3APAS_uc002z... Hybrid_Cap...
MSH3 p.PPA66del 5 79950742 79950750 PC3_PROSTATE 37 In_Frame_Del Del CCCCC... - rs60484572;rs1047489 uc003kgz.2 DHFR_uc011ctl.1... Hybrid_Cap...
NCAM1 11 112832307 112832308 PC3_PROSTATE 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 PC3_PROSTATE 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 PC3_PROSTATE 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 PC3_PROSTATE 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
OBSCN p.I2866V 1 228470844 228470844 PC3_PROSTATE 37 Missense_Mutation SNP A G uc009xez.1 OBSCN_uc001hsn.... Hybrid_Cap... view
PAX3 2 223158653 223158653 PC3_PROSTATE 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PCDH15 p.I409N 10 55955537 55955537 PC3_PROSTATE 37 Missense_Mutation SNP A T uc010qhy.1 PCDH15_uc010qhq... Hybrid_Cap... view
PDE4DIP p.Q1665fs 1 144873963 144873963 PC3_PROSTATE 37 Frame_Shift_Del Del T - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDE4DIP p.V486fs 1 144917828 144917828 PC3_PROSTATE 37 Frame_Shift_Del Del A - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PGR 11 100933598 100933599 PC3_PROSTATE 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PIK3C2G p.P129del 12 18435399 18435401 PC3_PROSTATE 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PIK3C2G 12 18800990 18800990 PC3_PROSTATE 37 3'UTR Del A - rs16914368 uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PRKCZ p.S148R 1 2075672 2075672 PC3_PROSTATE 37 Missense_Mutation SNP C G uc001aiq.2 PRKCZ_uc001air.... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 PC3_PROSTATE 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 PC3_PROSTATE 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
ROBO2 p.A54V 3 77147264 77147264 PC3_PROSTATE 37 Missense_Mutation SNP C T uc003dpz.2 ROBO2_uc003dpy.... Hybrid_Cap... view
SEPT9 17 75494787 75494788 PC3_PROSTATE 37 3'UTR Ins - C rs5822173 uc002jts.3 SEPT9_uc010wtk.... Hybrid_Cap...
TCF21 6 134210497 134210498 PC3_PROSTATE 37 5'UTR Ins - TCTC rs35199378 uc003qei.3 TCF21_uc003qej.... Hybrid_Cap...
TFPT p.E63D 19 54617915 54617915 PC3_PROSTATE 37 Missense_Mutation SNP C G uc010yej.1 TFPT_uc010erd.2... Hybrid_Cap... view
TMEM123 11 102269398 102269398 PC3_PROSTATE 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TP53 p.A138fs 17 7578516 7578516 PC3_PROSTATE 37 Frame_Shift_Del Del G - uc002gim.2 TP53_uc002gig.1... Hybrid_Cap...
TP63 3 189507518 189507519 PC3_PROSTATE 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TRPS1 8 116635872 116635873 PC3_PROSTATE 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TRRAP p.R696H 7 98509724 98509724 PC3_PROSTATE 37 Missense_Mutation SNP G A uc003upp.2 TRRAP_uc011kis.... Hybrid_Cap... view
TSC2 16 2138671 2138672 PC3_PROSTATE 37 3'UTR Del AA - uc002con.2 TSC2_uc010bsd.2... Hybrid_Cap...
TTN p.G7623R 2 179578786 179578786 PC3_PROSTATE 37 Missense_Mutation SNP C T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 PC3_PROSTATE 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...