Annotation Summary for Cell Line: RPMI-7951  

Cell line primary name: RPMI-7951
Cell line aliases:
Gender: F
Site Primary: skin
Histology: malignant_melanoma
Hist Subtype1: NS
Notes:
Source: ATCC
Expression arrays: CRAZY_p_NCLE_RNA10_HG-U133_Plus_2_A06_569534
SNP arrays: HONEY_p_NCLE_DNAAffy3_S_GenomeWideSNP_6_H05_293456
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in RPMI-7951

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ADAM17 2 9630245 9630245 RPMI7951_SKIN 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
AGAP2 p.E906K 12 58121770 58121770 RPMI7951_SKIN 37 Missense_Mutation SNP C T uc001spq.2 AGAP2_uc001spo.... Hybrid_Cap... view
AKAP12 p.1531_1532insE 6 151674116 151674117 RPMI7951_SKIN 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP9 p.1335_1336insQ 7 91652178 91652179 RPMI7951_SKIN 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ALPK1 4 113347609 113347610 RPMI7951_SKIN 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 RPMI7951_SKIN 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ALPK2 p.V417F 18 56246759 56246759 RPMI7951_SKIN 37 Missense_Mutation SNP C A uc002lhj.3 Hybrid_Cap... view
BCKDK 16 31123595 31123595 RPMI7951_SKIN 37 3'UTR SNP C T uc002eaw.3 BCKDK_uc002eav.... Hybrid_Cap... view
BRAF p.V600E 7 140453136 140453136 RPMI7951_SKIN 37 Missense_Mutation SNP A T rs113488022 uc003vwc.3 Hybrid_Cap... view
BRIP1 p.P210H 17 59886117 59886117 RPMI7951_SKIN 37 Missense_Mutation SNP G T uc002izk.1 Hybrid_Cap... view
C1ORF86 1 2115986 2115986 RPMI7951_SKIN 37 3'UTR SNP G A uc001aix.1 PRKCZ_uc001aiq.... Hybrid_Cap... view
CDK8 13 26978253 26978253 RPMI7951_SKIN 37 3'UTR SNP A T uc001uqr.1 CDK8_uc001uqs.1... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 RPMI7951_SKIN 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN5 p.E1003K 11 100211914 100211914 RPMI7951_SKIN 37 Missense_Mutation SNP G A uc001pga.2 CNTN5_uc001pgb.... Hybrid_Cap... view
CNTN6 3 1339681 1339686 RPMI7951_SKIN 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
CTBP2 p.K974fs 10 126678123 126678123 RPMI7951_SKIN 37 Frame_Shift_Del Del T - uc001lie.3 CTBP2_uc009yak.... Hybrid_Cap...
DYRK4 p.Q504* 12 4722866 4722866 RPMI7951_SKIN 37 Nonsense_Mutation SNP C T uc001qmx.2 DYRK4_uc001qmy.... Hybrid_Cap... view
EIF4G1 p.H642R 3 184040717 184040717 RPMI7951_SKIN 37 Missense_Mutation SNP A G uc010hxx.2 EIF4G1_uc003fno... Hybrid_Cap... view
EP300 22 41574970 41574972 RPMI7951_SKIN 37 3'UTR Del GTA - rs76489032 uc003azl.3 Hybrid_Cap...
ETV1 7 14028708 14028708 RPMI7951_SKIN 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FGFR1OP 6 167453519 167453520 RPMI7951_SKIN 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
GRIA3 X 122318386 122318387 RPMI7951_SKIN 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
HDAC4 p.L175* 2 240085586 240085586 RPMI7951_SKIN 37 Nonsense_Mutation SNP A C uc002vyk.3 HDAC4_uc010fyz.... Hybrid_Cap... view
MAML2 p.604_607QQQQ>Q 11 95825375 95825383 RPMI7951_SKIN 37 In_Frame_Del Del TGCTG... - rs113349418 uc001pfw.1 Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 RPMI7951_SKIN 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 RPMI7951_SKIN 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 RPMI7951_SKIN 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAPKBP1 p.E259E 15 42105257 42105257 RPMI7951_SKIN 37 Silent SNP G A uc001zok.3 MAPKBP1_uc001zo... Hybrid_Cap... view
MET p.T17I 7 116339188 116339188 RPMI7951_SKIN 37 Missense_Mutation SNP C T uc010lkh.2 MET_uc003vij.2_... Hybrid_Cap... view
MGA p.P608Q 15 41989031 41989031 RPMI7951_SKIN 37 Missense_Mutation SNP C A uc010ucy.1 MGA_uc001zog.1_... Hybrid_Cap... view
NCAM1 11 112832307 112832308 RPMI7951_SKIN 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 RPMI7951_SKIN 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA3 p.Q1276del 20 46279837 46279839 RPMI7951_SKIN 37 In_Frame_Del Del CAG - rs2664555 uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NCOA3 20 46282339 46282340 RPMI7951_SKIN 37 3'UTR Ins - AT uc002xtk.2 NCOA3_uc002xtl.... Hybrid_Cap...
NFIA p.S265L 1 61798217 61798217 RPMI7951_SKIN 37 Missense_Mutation SNP C T uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap... view
NPR1 1 153665919 153665920 RPMI7951_SKIN 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NUP214 9 134067556 134067557 RPMI7951_SKIN 37 Intron Ins - T rs66652901 uc004cag.2 NUP214_uc004cah... Hybrid_Cap...
PIK3C2G p.P129del 12 18435399 18435401 RPMI7951_SKIN 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
POU5F1 p.E91K 6 31138127 31138127 RPMI7951_SKIN 37 Missense_Mutation SNP C T uc003nsv.2 Hybrid_Cap... view
PRKD3 2 37480319 37480320 RPMI7951_SKIN 37 Stop_Codon_Ins Ins - T rs79875666 uc002rqd.2 Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 RPMI7951_SKIN 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 RPMI7951_SKIN 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RET p.S401C 10 43604616 43604616 RPMI7951_SKIN 37 Missense_Mutation SNP A T uc001jal.2 RET_uc001jak.1_... Hybrid_Cap... view
ROR2 p.S670F 9 94486767 94486767 RPMI7951_SKIN 37 Missense_Mutation SNP G A uc004arj.1 ROR2_uc004ari.1... Hybrid_Cap... view
RPS6KA5 14 91360733 91360734 RPMI7951_SKIN 37 Intron Ins - T rs77438853 uc001xys.2 RPS6KA5_uc010tw... Hybrid_Cap...
SP1 p.A738T 12 53804878 53804878 RPMI7951_SKIN 37 Missense_Mutation SNP G A uc001scw.2 SP1_uc010sog.1_... Hybrid_Cap... view
TP53 p.S166* 17 7578433 7578433 RPMI7951_SKIN 37 Nonsense_Mutation SNP G T uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TRIM33 p.P451L 1 114969867 114969867 RPMI7951_SKIN 37 Missense_Mutation SNP G A uc001eew.2 TRIM33_uc010owr... Hybrid_Cap... view
TTN 2 179391639 179391640 RPMI7951_SKIN 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.R29051* 2 179411203 179411203 RPMI7951_SKIN 37 Nonsense_Mutation SNP G A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
UNC13C p.G994* 15 54308080 54308080 RPMI7951_SKIN 37 Nonsense_Mutation SNP G T uc002ack.2 Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 RPMI7951_SKIN 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...