Annotation Summary for Cell Line: RPMI-8402  

Cell line primary name: RPMI-8402
Cell line aliases:
Gender: F
Site Primary: haematopoietic_and_lymphoid_tissue
Histology: lymphoid_neoplasm
Hist Subtype1: acute_lymphoblastic_T_cell_leukaemia
Notes:
Source: DSMZ
Expression arrays: WATCH_p_NCLE_RNA8_HG-U133_Plus_2_C04_474596
SNP arrays: CHARY_p_NCLE_DNAAffy9_GenomeWideSNP_6_F08_490420
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in RPMI-8402

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ACACA 17 35766564 35766564 RPMI8402_HAEMAT... 37 5'UTR Del A - uc002hno.2 ACACA_uc002hnn.... Hybrid_Cap...
ADAM17 2 9630245 9630245 RPMI8402_HAEMAT... 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 RPMI8402_HAEMAT... 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 RPMI8402_HAEMAT... 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP9 p.1335_1336insQ 7 91652178 91652179 RPMI8402_HAEMAT... 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ALPK1 4 113347609 113347610 RPMI8402_HAEMAT... 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 RPMI8402_HAEMAT... 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
BIRC6 p.S1112A 2 32658797 32658797 RPMI8402_HAEMAT... 37 Missense_Mutation SNP T G uc010ezu.2 Hybrid_Cap... view
BIRC6 2 32843085 32843085 RPMI8402_HAEMAT... 37 3'UTR SNP T C uc010ezu.2 Hybrid_Cap... view
BRD2 p.E500del 6 32945699 32945701 RPMI8402_HAEMAT... 37 In_Frame_Del Del GAG - uc010juh.2 BRD2_uc003ocn.3... Hybrid_Cap...
CABC1 1 227171585 227171585 RPMI8402_HAEMAT... 37 Intron Del T - uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CABC1 1 227171736 227171739 RPMI8402_HAEMAT... 37 Intron Del GGGG - rs1574184;rs114483791;rs1574185 uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CACNA1F p.D167E X 49087332 49087332 RPMI8402_HAEMAT... 37 Missense_Mutation SNP G T uc004dnb.2 CACNA1F_uc010ni... Hybrid_Cap... view
CACNB2 10 18828721 18828722 RPMI8402_HAEMAT... 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CARD10 p.KE272del 22 37906309 37906314 RPMI8402_HAEMAT... 37 In_Frame_Del Del CTCCT... - uc003asx.1 CARD10_uc003ast... Hybrid_Cap...
CHD1 p.P1684del 5 98192165 98192167 RPMI8402_HAEMAT... 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CLK3 p.S157S 15 74911564 74911564 RPMI8402_HAEMAT... 37 Silent SNP C G uc010uln.1 CLK3_uc002ayg.3... Hybrid_Cap... view
CNTN5 p.G315E 11 99872832 99872832 RPMI8402_HAEMAT... 37 Missense_Mutation SNP G A uc001pga.2 CNTN5_uc009ywv.... Hybrid_Cap... view
CXCL12 10 44873992 44873993 RPMI8402_HAEMAT... 37 Intron Ins - CT rs117617571 uc001jbh.2 CXCL12_uc001jbf... Hybrid_Cap...
CYFIP1 p.S794T 15 22963866 22963866 RPMI8402_HAEMAT... 37 Missense_Mutation SNP T A uc001yus.2 CYFIP1_uc001yut... Hybrid_Cap... view
DFFB 1 3782280 3782280 RPMI8402_HAEMAT... 37 Intron SNP G T uc010nzn.1 DFFB_uc001alc.2... Hybrid_Cap... view
ETV1 7 14028708 14028708 RPMI8402_HAEMAT... 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
EWSR1 22 29687485 29687485 RPMI8402_HAEMAT... 37 Intron SNP C T uc003aev.2 EWSR1_uc003aet.... Hybrid_Cap... view
FASN p.A1303S 17 80043573 80043573 RPMI8402_HAEMAT... 37 Missense_Mutation SNP C A uc002kdu.2 FASN_uc002kdw.1... Hybrid_Cap... view
FBN2 p.D1975N 5 127637197 127637197 RPMI8402_HAEMAT... 37 Missense_Mutation SNP C T uc003kuu.2 Hybrid_Cap... view
FBXW7 p.R465H 4 153249384 153249384 RPMI8402_HAEMAT... 37 Missense_Mutation SNP C T uc003ims.2 FBXW7_uc011cii.... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 RPMI8402_HAEMAT... 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 RPMI8402_HAEMAT... 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
GPR112 p.D2657del X 135474445 135474447 RPMI8402_HAEMAT... 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 RPMI8402_HAEMAT... 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 RPMI8402_HAEMAT... 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HRAS p.A134S 11 533503 533503 RPMI8402_HAEMAT... 37 Missense_Mutation SNP C A uc001lpv.2 HRAS_uc010qvw.1... Hybrid_Cap... view
IL1R2 p.L337V 2 102642694 102642694 RPMI8402_HAEMAT... 37 Missense_Mutation SNP C G uc002tbm.2 IL1R2_uc002tbn.... Hybrid_Cap... view
ILK 11 6630029 6630029 RPMI8402_HAEMAT... 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITGA5 p.G579V 12 54797449 54797449 RPMI8402_HAEMAT... 37 Missense_Mutation SNP C A uc001sga.2 Hybrid_Cap... view
ITK p.N151H 5 156641327 156641327 RPMI8402_HAEMAT... 37 Missense_Mutation SNP A C uc003lwo.1 Hybrid_Cap... view
ITPR2 p.R470_splice 12 26834804 26834805 RPMI8402_HAEMAT... 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KIAA1409 p.I1349T 14 94088090 94088090 RPMI8402_HAEMAT... 37 Missense_Mutation SNP T C uc001ybv.1 KIAA1409_uc001y... Hybrid_Cap... view
KLK7 19 51480672 51480675 RPMI8402_HAEMAT... 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LRP1B p.R3239G 2 141215131 141215131 RPMI8402_HAEMAT... 37 Missense_Mutation SNP G C uc002tvj.1 Hybrid_Cap... view
MAML2 p.604_607QQQQ>Q 11 95825375 95825383 RPMI8402_HAEMAT... 37 In_Frame_Del Del TGCTG... - rs113349418 uc001pfw.1 Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 RPMI8402_HAEMAT... 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 RPMI8402_HAEMAT... 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 RPMI8402_HAEMAT... 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAP3K4 p.S260Y 6 161470083 161470083 RPMI8402_HAEMAT... 37 Missense_Mutation SNP C A uc003qtn.2 MAP3K4_uc010kkc... Hybrid_Cap... view
MAP3K5 p.R298S 6 137018438 137018438 RPMI8402_HAEMAT... 37 Missense_Mutation SNP T G uc003qhc.2 MAP3K5_uc011edk... Hybrid_Cap... view
MAPKAPK3 3 50685575 50685575 RPMI8402_HAEMAT... 37 3'UTR Del A - rs76026164 uc003day.1 MAPKAPK3_uc003d... Hybrid_Cap...
MGA p.Q901* 15 42003164 42003164 RPMI8402_HAEMAT... 37 Nonsense_Mutation SNP C T uc010ucy.1 MGA_uc001zog.1_... Hybrid_Cap... view
MSH6 2 48010309 48010309 RPMI8402_HAEMAT... 37 5'UTR SNP C T uc002rwd.3 MSH6_uc002rwc.2... Hybrid_Cap... view
MYLK p.G1317G 3 123382986 123382986 RPMI8402_HAEMAT... 37 Silent SNP G T uc003ego.2 MYLK_uc010hrr.2... Hybrid_Cap... view
MYO3A p.W21R 10 26241100 26241100 RPMI8402_HAEMAT... 37 Missense_Mutation SNP T C uc001isn.2 MYO3A_uc009xko.... Hybrid_Cap... view
NCAM1 11 112832307 112832308 RPMI8402_HAEMAT... 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 RPMI8402_HAEMAT... 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA3 p.Q1276del 20 46279837 46279839 RPMI8402_HAEMAT... 37 In_Frame_Del Del CAG - rs2664555 uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 RPMI8402_HAEMAT... 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NF1 17 29701274 29701274 RPMI8402_HAEMAT... 37 3'UTR SNP T C uc002hgg.2 NF1_uc002hgh.2_... Hybrid_Cap... view
NOTCH4 p.15_16LL>L 6 32191659 32191661 RPMI8402_HAEMAT... 37 In_Frame_Del Del AGC - uc003obb.2 NOTCH4_uc011dpu... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 RPMI8402_HAEMAT... 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NR4A3 p.M144I 9 102590723 102590723 RPMI8402_HAEMAT... 37 Missense_Mutation SNP G A uc004bai.2 NR4A3_uc004bae.... Hybrid_Cap... view
OBSCN p.E4670K 1 228505751 228505751 RPMI8402_HAEMAT... 37 Missense_Mutation SNP G A uc009xez.1 OBSCN_uc001hsn.... Hybrid_Cap... view
PAK7 p.V710I 20 9520141 9520141 RPMI8402_HAEMAT... 37 Missense_Mutation SNP C T uc002wnl.2 PAK7_uc002wnk.2... Hybrid_Cap... view
PAX3 2 223158653 223158653 RPMI8402_HAEMAT... 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PKHD1 p.Y3737H 6 51513984 51513984 RPMI8402_HAEMAT... 37 Missense_Mutation SNP A G uc003pah.1 Hybrid_Cap... view
PPARG p.E28K 3 12393173 12393173 RPMI8402_HAEMAT... 37 Missense_Mutation SNP G A uc003bwx.2 PPARG_uc003bwr.... Hybrid_Cap... view
PRKCA 17 64298959 64298960 RPMI8402_HAEMAT... 37 5'UTR Ins - GG rs71160558 uc002jfp.1 PRKCA_uc002jfo.... Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 RPMI8402_HAEMAT... 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PTEN p.R159S 10 89692993 89692993 RPMI8402_HAEMAT... 37 Missense_Mutation SNP G T uc001kfb.2 Hybrid_Cap... view
RECQL4 p.R766fs 8 145738768 145738768 RPMI8402_HAEMAT... 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RIF1 p.D1516N 2 152320580 152320580 RPMI8402_HAEMAT... 37 Missense_Mutation SNP G A uc002txm.2 RIF1_uc002txl.2... Hybrid_Cap... view
SERPINB1 p.R80L 6 2838850 2838850 RPMI8402_HAEMAT... 37 Missense_Mutation SNP C A uc003mub.2 SERPINB1_uc003m... Hybrid_Cap... view
SOX2 p.P289S 3 181431013 181431013 RPMI8402_HAEMAT... 37 Missense_Mutation SNP C T uc003fkx.2 SOX2OT_uc003fkv... Hybrid_Cap... view
SPEG p.P751P 2 220315997 220315997 RPMI8402_HAEMAT... 37 Silent SNP C T uc010fwg.2 SPEG_uc002vlm.2... Hybrid_Cap... view
TAF15 p.R535H 17 34171907 34171907 RPMI8402_HAEMAT... 37 Missense_Mutation SNP G A uc002hkd.2 TAF15_uc002hkc.... Hybrid_Cap... view
TLX1 10 102896686 102896686 RPMI8402_HAEMAT... 37 3'UTR SNP C T uc001ksw.2 Hybrid_Cap... view
TP53 p.R273C 17 7577121 7577121 RPMI8402_HAEMAT... 37 Missense_Mutation SNP G A uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TRPS1 8 116635872 116635873 RPMI8402_HAEMAT... 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TSC2 p.A614T 16 2121511 2121511 RPMI8402_HAEMAT... 37 Missense_Mutation SNP G A uc002con.2 TSC2_uc010bsd.2... Hybrid_Cap... view
TTN p.V19793A 2 179444932 179444932 RPMI8402_HAEMAT... 37 Missense_Mutation SNP A G uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.I1899N 2 179640895 179640895 RPMI8402_HAEMAT... 37 Missense_Mutation SNP A T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.L161I 2 179665224 179665224 RPMI8402_HAEMAT... 37 Missense_Mutation SNP A T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 RPMI8402_HAEMAT... 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
WHSC1 p.E1099K 4 1962801 1962801 RPMI8402_HAEMAT... 37 Missense_Mutation SNP G A uc003gdz.3 WHSC1_uc003geb.... Hybrid_Cap... view
WIF1 p.V133_splice 12 65462686 65462686 RPMI8402_HAEMAT... 37 Splice_Site_SNP SNP T A uc001ssk.2 Hybrid_Cap... view
WNK2 9 96079979 96079979 RPMI8402_HAEMAT... 37 Intron SNP C A uc004ati.1 WNK2_uc011lud.1... Hybrid_Cap... view
WT1 p.S189* 11 32456326 32456326 RPMI8402_HAEMAT... 37 Nonsense_Mutation SNP G T uc001mtn.1 WT1_uc001mto.1_... Hybrid_Cap... view
XPO5 p.F366_splice 6 43528042 43528042 RPMI8402_HAEMAT... 37 Splice_Site_SNP SNP T A uc003ovp.2 Hybrid_Cap... view