Annotation Summary for Cell Line: RT-112  

Cell line primary name: RT-112
Cell line aliases:
Gender: F
Site Primary: urinary_tract
Histology: carcinoma
Hist Subtype1: transitional_cell_carcinoma
Notes: RT112/84 is a clonal derivative of RT112
Source: DSMZ
Expression arrays: PARES_p_NCLE_RNA_Redo_HG-U133_Plus_2_C01_257646
SNP arrays: LIMPS_p_NCLE_DNA2N_GenomeWideSNP_6_H06_246788
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in RT-112

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ACACA 17 35766564 35766564 RT112_URINARY_T... 37 5'UTR Del A - uc002hno.2 ACACA_uc002hnn.... Hybrid_Cap...
ACACB p.P2194L 12 109698369 109698369 RT112_URINARY_T... 37 Missense_Mutation SNP C T uc001tob.2 ACACB_uc001toc.... Hybrid_Cap... view
ADAM28 8 24211994 24211997 RT112_URINARY_T... 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADAM29 p.L691del 4 175898744 175898746 RT112_URINARY_T... 37 In_Frame_Del Del TTA - uc003iuc.2 ADAM29_uc003iud... Hybrid_Cap...
AIM1 p.N1303K 6 106992539 106992539 RT112_URINARY_T... 37 Missense_Mutation SNP T A uc003prh.2 AIM1_uc003pri.2... Hybrid_Cap... view
AKAP12 p.1531_1532insE 6 151674116 151674117 RT112_URINARY_T... 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP9 p.1335_1336insQ 7 91652178 91652179 RT112_URINARY_T... 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 RT112_URINARY_T... 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ASPH p.A264_splice 8 62550924 62550925 RT112_URINARY_T... 37 Splice_Site_Ins Ins - A rs5891816 uc003xuj.2 ASPH_uc011leg.1... Hybrid_Cap...
BCR 22 23631813 23631814 RT112_URINARY_T... 37 Intron Ins - C rs66503844 uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BCR 22 23632777 23632778 RT112_URINARY_T... 37 Intron Ins - T uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
CABC1 1 227171585 227171585 RT112_URINARY_T... 37 Intron Del T - uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CACNB2 10 18828721 18828722 RT112_URINARY_T... 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CARD14 17 78172538 78172538 RT112_URINARY_T... 37 Intron SNP C T uc002jxw.1 CARD14_uc002jxt... Hybrid_Cap... view
CDK11B 1 1654066 1654068 RT112_URINARY_T... 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CHD1 p.P1684del 5 98192165 98192167 RT112_URINARY_T... 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CHD9 p.2164_2165SS>S 16 53338410 53338412 RT112_URINARY_T... 37 In_Frame_Del Del TTC - uc002ehb.2 CHD9_uc002egy.2... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 RT112_URINARY_T... 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN5 p.I513V 11 99944983 99944983 RT112_URINARY_T... 37 Missense_Mutation SNP A G rs61759482 uc001pga.2 CNTN5_uc009ywv.... Hybrid_Cap... view
CNTN6 3 1339681 1339686 RT112_URINARY_T... 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
CREB3L2 p.T100del 7 137612914 137612916 RT112_URINARY_T... 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CXCL12 10 44873992 44873993 RT112_URINARY_T... 37 Intron Ins - CT rs117617571 uc001jbh.2 CXCL12_uc001jbf... Hybrid_Cap...
DACH1 13 72014625 72014626 RT112_URINARY_T... 37 3'UTR Ins - T rs117109529 uc010thn.1 DACH1_uc010tho.... Hybrid_Cap...
DDR2 1 162750211 162750211 RT112_URINARY_T... 37 3'UTR Del T - uc001gcf.2 DDR2_uc001gcg.2... Hybrid_Cap...
DMPK p.V173I 19 46281893 46281893 RT112_URINARY_T... 37 Missense_Mutation SNP C T uc002pdi.1 DMPK_uc010xxs.1... Hybrid_Cap... view
DYRK1A 21 38884966 38884967 RT112_URINARY_T... 37 3'UTR Ins - T rs72430212 uc002ywk.2 DYRK1A_uc002ywi... Hybrid_Cap...
EDN1 6 12290729 12290729 RT112_URINARY_T... 37 5'UTR Del A - uc003nae.3 EDN1_uc010jpb.2... Hybrid_Cap...
EIF4B p.S548F 12 53433073 53433073 RT112_URINARY_T... 37 Missense_Mutation SNP C T uc010snu.1 EIF4B_uc001sbh.... Hybrid_Cap... view
EIF4E 4 99808137 99808141 RT112_URINARY_T... 37 Intron Del TTAAA - uc011ceb.1 EIF4E_uc011cea.... Hybrid_Cap...
EP300 22 41574970 41574972 RT112_URINARY_T... 37 3'UTR Del GTA - rs76489032 uc003azl.3 Hybrid_Cap...
EPHA6 3 97367230 97367231 RT112_URINARY_T... 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
EPHA7 p.T902I 6 93956531 93956531 RT112_URINARY_T... 37 Missense_Mutation SNP G A uc003poe.2 EPHA7_uc003pof.... Hybrid_Cap... view
ETV1 7 14028708 14028708 RT112_URINARY_T... 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
EXT1 8 118811807 118811807 RT112_URINARY_T... 37 3'UTR Del T - uc003yok.1 Hybrid_Cap...
FGFR1OP 6 167453519 167453520 RT112_URINARY_T... 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 RT112_URINARY_T... 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLCN p.W299R 17 17122500 17122500 RT112_URINARY_T... 37 Missense_Mutation SNP A T uc002gra.3 PLD6_uc010cpn.2... Hybrid_Cap... view
FLCN p.E295K 17 17122512 17122512 RT112_URINARY_T... 37 Missense_Mutation SNP C T uc002gra.3 PLD6_uc010cpn.2... Hybrid_Cap... view
FLCN 17 17124733 17124733 RT112_URINARY_T... 37 Intron SNP C A uc002gra.3 PLD6_uc010cpn.2... Hybrid_Cap... view
FLI1 11 128638217 128638217 RT112_URINARY_T... 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLNC p.T1289M 7 128486119 128486119 RT112_URINARY_T... 37 Missense_Mutation SNP C T uc003vnz.3 FLNC_uc003voa.3... Hybrid_Cap... view
FN1 2 216244182 216244185 RT112_URINARY_T... 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GATS 7 99799198 99799198 RT112_URINARY_T... 37 3'UTR SNP C T uc003uua.3 STAG3_uc010lgs.... Hybrid_Cap... view
GLI1 p.S576F 12 57864250 57864250 RT112_URINARY_T... 37 Missense_Mutation SNP C T uc001snx.2 GLI1_uc009zpq.2... Hybrid_Cap... view
GPR112 p.D2657del X 135474445 135474447 RT112_URINARY_T... 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 RT112_URINARY_T... 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 RT112_URINARY_T... 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HIF1A 14 62213929 62213930 RT112_URINARY_T... 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HNF1A 12 121434630 121434631 RT112_URINARY_T... 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
HSP90AB1 p.Q18E 6 44216418 44216418 RT112_URINARY_T... 37 Missense_Mutation SNP C G uc003oxa.1 HSP90AB1_uc011d... Hybrid_Cap... view
HSP90B1 p.E791del 12 104341188 104341190 RT112_URINARY_T... 37 In_Frame_Del Del GAA - rs117491163 uc001tkb.1 HSP90B1_uc010sw... Hybrid_Cap...
IL21R 16 27460779 27460780 RT112_URINARY_T... 37 3'UTR Ins - TG rs66690088 uc002doq.1 IL21R_uc002dor.... Hybrid_Cap...
ILK 11 6630029 6630029 RT112_URINARY_T... 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 RT112_URINARY_T... 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KDM6A p.P1191fs X 44942835 44942835 RT112_URINARY_T... 37 Frame_Shift_Del Del C - uc011mkz.1 KDM6A_uc004dge.... Hybrid_Cap...
KLK7 19 51480672 51480675 RT112_URINARY_T... 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
MAML2 p.604_607QQQQ>Q 11 95825375 95825383 RT112_URINARY_T... 37 In_Frame_Del Del TGCTG... - rs113349418 uc001pfw.1 Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 RT112_URINARY_T... 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP2K1 15 66679649 66679650 RT112_URINARY_T... 37 5'UTR Ins - C rs67229745 uc010bhq.2 Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 RT112_URINARY_T... 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 RT112_URINARY_T... 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAPKAPK3 3 50685575 50685575 RT112_URINARY_T... 37 3'UTR Del A - rs76026164 uc003day.1 MAPKAPK3_uc003d... Hybrid_Cap...
MCM3APAS 21 47671275 47671276 RT112_URINARY_T... 37 3'UTR Ins - AAT rs67797185 uc002zin.2 MCM3APAS_uc002z... Hybrid_Cap...
MLKL p.D369fs 16 74709591 74709594 RT112_URINARY_T... 37 Frame_Shift_Del Del TCTG - uc002fdb.2 MLKL_uc002fdc.2... Hybrid_Cap...
MLL3 p.A1691T 7 151882654 151882654 RT112_URINARY_T... 37 Missense_Mutation SNP C T uc003wla.2 MLL3_uc003wkz.2... Hybrid_Cap... view
MLLT3 9 20346377 20346378 RT112_URINARY_T... 37 3'UTR Ins - A rs66943046 uc003zoe.2 MLLT3_uc011lne.... Hybrid_Cap...
MLLT4 p.I539T 6 168303035 168303035 RT112_URINARY_T... 37 Missense_Mutation SNP T C uc003qwd.2 MLLT4_uc003qwb.... Hybrid_Cap... view
MYC p.L97F 8 128750752 128750752 RT112_URINARY_T... 37 Missense_Mutation SNP C T uc003ysi.2 MYC_uc003ysh.1_... Hybrid_Cap... view
NACA p.P48S 12 57115172 57115172 RT112_URINARY_T... 37 Missense_Mutation SNP G A uc009zoy.1 NACA_uc001slz.2... Hybrid_Cap... view
NCAM1 11 112832307 112832308 RT112_URINARY_T... 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 RT112_URINARY_T... 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 RT112_URINARY_T... 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NF1 p.L790P 17 29554584 29554584 RT112_URINARY_T... 37 Missense_Mutation SNP T C uc002hgg.2 NF1_uc002hgh.2_... Hybrid_Cap... view
NF1 p.K1844N 17 29654780 29654780 RT112_URINARY_T... 37 Missense_Mutation SNP G T uc002hgg.2 NF1_uc002hgh.2_... Hybrid_Cap... view
NPM1 5 170837734 170837734 RT112_URINARY_T... 37 3'UTR Del T - uc011dex.1 NPM1_uc003mbi.2... Hybrid_Cap...
NPR1 1 153665919 153665920 RT112_URINARY_T... 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 RT112_URINARY_T... 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NRK p.F196I X 105142582 105142582 RT112_URINARY_T... 37 Missense_Mutation SNP T A uc004emd.2 NRK_uc010npc.1_... Hybrid_Cap... view
NUP214 9 134067556 134067557 RT112_URINARY_T... 37 Intron Ins - T rs66652901 uc004cag.2 NUP214_uc004cah... Hybrid_Cap...
PAX3 2 223158653 223158653 RT112_URINARY_T... 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PGR 11 100933598 100933599 RT112_URINARY_T... 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PIK3C2G p.P129del 12 18435399 18435401 RT112_URINARY_T... 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PPP1R3A p.Q662fs 7 113519161 113519162 RT112_URINARY_T... 37 Frame_Shift_Del Del CT - uc010ljy.1 Hybrid_Cap...
PRKD3 2 37480319 37480320 RT112_URINARY_T... 37 Stop_Codon_Ins Ins - T rs79875666 uc002rqd.2 Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 RT112_URINARY_T... 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 RT112_URINARY_T... 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
ROBO1 p.1168_1169insG 3 78680431 78680432 RT112_URINARY_T... 37 In_Frame_Ins Ins - CCC uc003dqe.2 ROBO1_uc003dqb.... Hybrid_Cap...
ROBO2 p.R311* 3 77572050 77572050 RT112_URINARY_T... 37 Nonsense_Mutation SNP C T uc003dpz.2 ROBO2_uc003dpy.... Hybrid_Cap... view
ROR2 p.S471C 9 94487364 94487364 RT112_URINARY_T... 37 Missense_Mutation SNP G C uc004arj.1 ROR2_uc004ari.1... Hybrid_Cap... view
RPS6KA5 14 91360733 91360734 RT112_URINARY_T... 37 Intron Ins - T rs77438853 uc001xys.2 RPS6KA5_uc010tw... Hybrid_Cap...
RPS6KB1 17 58024224 58024225 RT112_URINARY_T... 37 3'UTR Ins - AA rs67846207 uc002ixy.2 RPS6KB1_uc010dd... Hybrid_Cap...
RPS6KL1 14 75373626 75373627 RT112_URINARY_T... 37 3'UTR Ins - TGAT uc001xqx.1 RPS6KL1_uc001xq... Hybrid_Cap...
SEPT9 p.V303M 17 75478411 75478411 RT112_URINARY_T... 37 Missense_Mutation SNP G A uc002jts.3 SEPT9_uc010wtk.... Hybrid_Cap... view
SFPQ p.E351Q 1 35656563 35656563 RT112_URINARY_T... 37 Missense_Mutation SNP C G uc001bys.2 SFPQ_uc001byr.2... Hybrid_Cap... view
SGK269 p.R303T 15 77473361 77473361 RT112_URINARY_T... 37 Missense_Mutation SNP C G uc002bcm.2 SGK269_uc002bcn... Hybrid_Cap... view
STK31 7 23872024 23872025 RT112_URINARY_T... 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TAB2 6 149731005 149731005 RT112_URINARY_T... 37 3'UTR SNP G A uc003qmj.2 TAB2_uc011eec.1... Hybrid_Cap... view
TCF21 6 134210497 134210498 RT112_URINARY_T... 37 5'UTR Ins - TCTC rs35199378 uc003qei.3 TCF21_uc003qej.... Hybrid_Cap...
TEC 4 48139307 48139310 RT112_URINARY_T... 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TMEM123 11 102269398 102269398 RT112_URINARY_T... 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TP53 p.R248Q 17 7577538 7577538 RT112_URINARY_T... 37 Missense_Mutation SNP C T rs11540652 uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TP53 p.S183* 17 7578382 7578382 RT112_URINARY_T... 37 Nonsense_Mutation SNP G C uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TRIM33 1 114940215 114940216 RT112_URINARY_T... 37 3'UTR Ins - G rs68133208 uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TRPS1 8 116635872 116635873 RT112_URINARY_T... 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TSC2 16 2138677 2138677 RT112_URINARY_T... 37 3'UTR SNP C T uc002con.2 TSC2_uc010bsd.2... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 RT112_URINARY_T... 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...