Annotation Summary for Cell Line: SBC-5  

Cell line primary name: SBC-5
Cell line aliases:
Gender:
Site Primary: lung
Histology: carcinoma
Hist Subtype1: small_cell_carcinoma
Notes:
Source: HSRRB
Expression arrays: METIS_p_NCLE_RNA1_Human_U133_Plus_2.0_B03_240878
SNP arrays: LIMPS_p_NCLE_DNA2N_GenomeWideSNP_6_F09_246746
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in SBC-5

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 SBC5_LUNG 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ADAM10 15 59041986 59041986 SBC5_LUNG 37 5'UTR SNP T A uc002afd.1 ADAM10_uc010bgc... Hybrid_Cap... view
ADAM28 8 24211994 24211997 SBC5_LUNG 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 SBC5_LUNG 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP9 p.1335_1336insQ 7 91652178 91652179 SBC5_LUNG 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ALPK2 p.A1200D 18 56203820 56203820 SBC5_LUNG 37 Missense_Mutation SNP G T uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap... view
ALS2 2 202587706 202587707 SBC5_LUNG 37 Intron Ins - A rs3219165 uc002uyo.2 ALS2_uc002uyp.3... Hybrid_Cap...
ATF1 p.T146R 12 51207901 51207901 SBC5_LUNG 37 Missense_Mutation SNP C G uc001rww.3 ATF1_uc010smu.1... Hybrid_Cap... view
ATP11A p.R638Q 13 113505454 113505454 SBC5_LUNG 37 Missense_Mutation SNP G A uc001vsj.3 ATP11A_uc001vsi... Hybrid_Cap... view
BTG1 12 92537706 92537707 SBC5_LUNG 37 3'UTR Ins - T rs33983967 uc001tby.3 BTG1_uc001tbv.1... Hybrid_Cap...
CACNB2 10 18828721 18828722 SBC5_LUNG 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CASP9 1 15820307 15820308 SBC5_LUNG 37 Intron Ins - C rs56104933 uc001awn.2 CASP9_uc001awm.... Hybrid_Cap...
CDK11B 1 1654066 1654068 SBC5_LUNG 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CHIC2 4 54876132 54876132 SBC5_LUNG 37 3'UTR Del C - rs4437313 uc003haj.1 PDGFRA_uc003haa... Hybrid_Cap...
CHRNA5 15 78885615 78885616 SBC5_LUNG 37 3'UTR Ins - TA rs72534078 uc002bdy.2 CHRNA3_uc002bea... Hybrid_Cap...
CIITA p.H408Y 16 11000568 11000568 SBC5_LUNG 37 Missense_Mutation SNP C T uc002daj.3 CIITA_uc002dai.... Hybrid_Cap... view
CIT p.E672A 12 120210641 120210641 SBC5_LUNG 37 Missense_Mutation SNP T G uc001txj.1 CIT_uc001txh.1_... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 SBC5_LUNG 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN6 3 1339681 1339686 SBC5_LUNG 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
CSF1R 5 149433400 149433401 SBC5_LUNG 37 3'UTR Ins - C rs66970099;rs78449650 uc003lrl.2 CSF1R_uc011dcd.... Hybrid_Cap...
DGKB 7 14216380 14216380 SBC5_LUNG 37 Intron Del A - uc003ssz.2 DGKB_uc011jxt.1... Hybrid_Cap...
DVL1 1 1284448 1284448 SBC5_LUNG 37 5'UTR SNP C T uc001aer.3 Hybrid_Cap... view
EDN1 6 12290729 12290729 SBC5_LUNG 37 5'UTR Del A - uc003nae.3 EDN1_uc010jpb.2... Hybrid_Cap...
EHBP1 p.M236T 2 63085613 63085613 SBC5_LUNG 37 Missense_Mutation SNP T C uc002sby.2 EHBP1_uc010fcp.... Hybrid_Cap... view
EIF4A1 p.E378E 17 7481717 7481717 SBC5_LUNG 37 Silent SNP A G uc002gho.1 EIF4A1_uc002ghr... Hybrid_Cap... view
EPHA3 p.I453T 3 89445038 89445039 SBC5_LUNG 37 Missense_Mutation DNP TC CA uc003dqy.2 EPHA3_uc003dqx.... Hybrid_Cap...
EPHA6 3 97367230 97367231 SBC5_LUNG 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
ERBB2 p.S1050L 17 37883246 37883246 SBC5_LUNG 37 Missense_Mutation SNP C T uc002hso.2 ERBB2_uc002hsm.... Hybrid_Cap... view
ETV1 p.A102S 7 13978803 13978803 SBC5_LUNG 37 Missense_Mutation SNP C A uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap... view
EXT1 8 118811807 118811807 SBC5_LUNG 37 3'UTR Del T - uc003yok.1 Hybrid_Cap...
FANCD2 3 10081677 10081677 SBC5_LUNG 37 Intron Del A - uc003buw.2 FANCD2_uc003bux... Hybrid_Cap...
FGFR2 p.E367K 10 123274822 123274822 SBC5_LUNG 37 Missense_Mutation SNP C T uc010qtj.1 FGFR2_uc010qtg.... Hybrid_Cap... view
FLI1 11 128638217 128638217 SBC5_LUNG 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLNC p.E1571K 7 128488745 128488745 SBC5_LUNG 37 Missense_Mutation SNP G A uc003vnz.3 FLNC_uc003voa.3... Hybrid_Cap... view
FLT3 13 28578112 28578112 SBC5_LUNG 37 3'UTR SNP A G uc001urw.2 FLT3_uc010aao.2... Hybrid_Cap... view
FN1 2 216244182 216244185 SBC5_LUNG 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GAS7 17 9939779 9939779 SBC5_LUNG 37 Intron SNP G A uc002gmg.1 GAS7_uc002gmj.1... Hybrid_Cap... view
GPR112 p.D2657del X 135474445 135474447 SBC5_LUNG 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 SBC5_LUNG 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 SBC5_LUNG 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HDAC2 6 114262087 114262087 SBC5_LUNG 37 3'UTR SNP G A uc003pwd.1 HDAC2_uc003pwc.... Hybrid_Cap... view
HERC2 p.L4387H 15 28369211 28369211 SBC5_LUNG 37 Missense_Mutation SNP A T uc001zbj.2 Hybrid_Cap... view
HIPK4 p.S406R 19 40886680 40886680 SBC5_LUNG 37 Missense_Mutation SNP A C rs56094851 uc002onp.2 Hybrid_Cap... view
HNF1A 12 121434630 121434631 SBC5_LUNG 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
HSP90B1 p.E791del 12 104341188 104341190 SBC5_LUNG 37 In_Frame_Del Del GAA - rs117491163 uc001tkb.1 HSP90B1_uc010sw... Hybrid_Cap...
ILK 11 6630029 6630029 SBC5_LUNG 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
INHBA 7 41729121 41729122 SBC5_LUNG 37 3'UTR Ins - T uc003thq.2 INHBA_uc003thr.... Hybrid_Cap...
ITGAV p.C698F 2 187529872 187529872 SBC5_LUNG 37 Missense_Mutation SNP G T uc002upq.2 ITGAV_uc010frs.... Hybrid_Cap... view
ITK p.T332N 5 156668665 156668665 SBC5_LUNG 37 Missense_Mutation SNP C A uc003lwo.1 Hybrid_Cap... view
KIAA1804 p.V1004M 1 233518356 233518356 SBC5_LUNG 37 Missense_Mutation SNP G A uc001hvt.3 KIAA1804_uc001h... Hybrid_Cap... view
KLK7 19 51480672 51480675 SBC5_LUNG 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LATS2 13 21620222 21620223 SBC5_LUNG 37 5'UTR Ins - A rs61240127;rs115723063 uc009zzs.2 LATS2_uc001unr.... Hybrid_Cap...
LIF p.T140T 22 30639829 30639829 SBC5_LUNG 37 Silent SNP G A uc003agz.2 LIF_uc011aks.1_... Hybrid_Cap... view
MAF p.D342G 16 79632775 79632775 SBC5_LUNG 37 Missense_Mutation SNP T C uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 SBC5_LUNG 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP2K6 p.A221_splice 17 67519783 67519783 SBC5_LUNG 37 Splice_Site_SNP SNP G T uc002jij.2 Hybrid_Cap... view
MAP3K1 p.T949del 5 56177849 56177851 SBC5_LUNG 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K4 p.I206L 6 161469920 161469920 SBC5_LUNG 37 Missense_Mutation SNP A T uc003qtn.2 MAP3K4_uc010kkc... Hybrid_Cap... view
MAPK7 p.A296T 17 19284408 19284408 SBC5_LUNG 37 Missense_Mutation SNP G A uc002gvn.2 B9D1_uc010cqm.1... Hybrid_Cap... view
MLL3 7 151834236 151834237 SBC5_LUNG 37 Intron Ins - G rs72575606 uc003wla.2 MLL3_uc003wkz.2... Hybrid_Cap...
MYB p.P325R 6 135516911 135516911 SBC5_LUNG 37 Missense_Mutation SNP C G uc003qfh.2 MYB_uc003qfc.2_... Hybrid_Cap... view
MYCL1 1 40366352 40366352 SBC5_LUNG 37 Intron SNP C T uc001cer.1 MYCL1_uc001ces.... Hybrid_Cap... view
MYH11 16 15797811 15797811 SBC5_LUNG 37 3'UTR SNP G T rs75821286 uc002ddx.2 MYH11_uc002ddv.... Hybrid_Cap... view
NCAM1 11 112832307 112832308 SBC5_LUNG 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 SBC5_LUNG 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA3 20 46282339 46282340 SBC5_LUNG 37 3'UTR Ins - AT uc002xtk.2 NCOA3_uc002xtl.... Hybrid_Cap...
NEK11 3 130748533 130748533 SBC5_LUNG 37 5'UTR SNP G A uc003eny.2 NEK11_uc003enx.... Hybrid_Cap... view
NEK3 p.K313_splice 13 52718050 52718051 SBC5_LUNG 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NEK3 p.S204_splice 13 52725278 52725279 SBC5_LUNG 37 Splice_Site_Ins Ins - A uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NF1 17 29556713 29556713 SBC5_LUNG 37 Intron SNP C T rs17882945 uc002hgg.2 NF1_uc002hgh.2_... Hybrid_Cap... view
NPM1 5 170837734 170837734 SBC5_LUNG 37 3'UTR Del T - uc011dex.1 NPM1_uc003mbi.2... Hybrid_Cap...
NPR1 1 153665919 153665920 SBC5_LUNG 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 SBC5_LUNG 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
PALB2 p.E1018D 16 23632742 23632742 SBC5_LUNG 37 Missense_Mutation SNP C G uc002dlx.1 Hybrid_Cap... view
PAX3 2 223066017 223066018 SBC5_LUNG 37 Intron Ins - C rs115619343 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PCDH15 p.G1156R 10 55663053 55663053 SBC5_LUNG 37 Missense_Mutation SNP C T uc010qhy.1 PCDH15_uc010qhq... Hybrid_Cap... view
PDE4DIP 1 144852285 144852285 SBC5_LUNG 37 3'UTR SNP C G uc001elw.3 NBPF10_uc009wir... Hybrid_Cap... view
PDE4DIP 1 144863860 144863861 SBC5_LUNG 37 Intron Ins - T rs33949841 uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDE4DIP p.E391E 1 144921856 144921856 SBC5_LUNG 37 Silent SNP C T uc001elw.3 NBPF10_uc009wir... Hybrid_Cap... view
PDE4DIP p.E243fs 1 144923729 144923729 SBC5_LUNG 37 Frame_Shift_Del Del T - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PGR 11 100933598 100933599 SBC5_LUNG 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PIK3C2G p.P129del 12 18435399 18435401 SBC5_LUNG 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PKHD1 6 51586669 51586669 SBC5_LUNG 37 Intron SNP T C uc003pah.1 PKHD1_uc010jzn.... Hybrid_Cap... view
PKN1 p.R166Q 19 14557242 14557242 SBC5_LUNG 37 Missense_Mutation SNP G A uc002myq.2 PKN1_uc002myp.2... Hybrid_Cap... view
PRKG1 10 54053913 54053914 SBC5_LUNG 37 3'UTR Ins - G rs35902208 uc001jjo.2 PRKG1_uc001jjm.... Hybrid_Cap...
PRRX1 p.R111P 1 170688957 170688957 SBC5_LUNG 37 Missense_Mutation SNP G C uc001ghf.2 PRRX1_uc001ghe.... Hybrid_Cap... view
RANBP9 p.Y294* 6 13657363 13657363 SBC5_LUNG 37 Nonsense_Mutation SNP G T uc003nbb.2 RANBP9_uc003nba... Hybrid_Cap... view
RARB 3 25470118 25470119 SBC5_LUNG 37 Intron Ins - A rs11403838 uc011awl.1 RARB_uc003cdi.1... Hybrid_Cap...
RBPJ 4 26321373 26321373 SBC5_LUNG 37 5'UTR SNP T A uc003grx.1 RBPJ_uc003gry.1... Hybrid_Cap... view
RBPJ 4 26431822 26431822 SBC5_LUNG 37 Intron Del A - rs76214390 uc003grx.1 RBPJ_uc003gry.1... Hybrid_Cap...
RIPK3 p.V156F 14 24808226 24808226 SBC5_LUNG 37 Missense_Mutation SNP C A uc001wpb.2 RIPK3_uc001wpa.... Hybrid_Cap... view
ROBO2 3 77666937 77666937 SBC5_LUNG 37 Intron Del A - rs78745603 uc003dpz.2 ROBO2_uc003dpy.... Hybrid_Cap...
SLC45A3 p.222_234ALGPTEPAEGLSA>A 1 205632218 205632253 SBC5_LUNG 37 In_Frame_Del Del GCCGA... - uc001hda.1 SLC45A3_uc010pr... Hybrid_Cap...
SMARCA4 p.R1243fs 19 11144148 11144149 SBC5_LUNG 37 Frame_Shift_Del Del GC - uc010dxo.2 SMARCA4_uc002mq... Hybrid_Cap...
STIL p.G1188V 1 47717112 47717112 SBC5_LUNG 37 Missense_Mutation SNP C A uc001crd.1 TAL1_uc001crb.1... Hybrid_Cap... view
STK17A p.A231_splice 7 43659323 43659323 SBC5_LUNG 37 Splice_Site_SNP SNP G T uc003tih.2 C7orf44_uc003ti... Hybrid_Cap... view
STK31 7 23872024 23872025 SBC5_LUNG 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
SUZ12 p.V613L 17 30323859 30323859 SBC5_LUNG 37 Missense_Mutation SNP G T uc002hgs.2 SUZ12_uc002hgt.... Hybrid_Cap... view
TEC 4 48139307 48139310 SBC5_LUNG 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TG p.C1493R 8 133931719 133931719 SBC5_LUNG 37 Missense_Mutation SNP T C uc003ytw.2 TG_uc010mdw.2_M... Hybrid_Cap... view
TGFB2 1 218519928 218519929 SBC5_LUNG 37 5'UTR Ins - AAAC uc001hln.2 TGFB2_uc001hll.... Hybrid_Cap...
TMEM123 11 102269398 102269398 SBC5_LUNG 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TP53 p.R248L 17 7577538 7577538 SBC5_LUNG 37 Missense_Mutation SNP C A rs11540652 uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TP63 3 189507518 189507519 SBC5_LUNG 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TRIM24 p.C243Y 7 138204030 138204030 SBC5_LUNG 37 Missense_Mutation SNP G A uc003vuc.2 TRIM24_uc003vub... Hybrid_Cap... view
TTN 2 179391639 179391640 SBC5_LUNG 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
VEGFC p.S419_splice 4 177605082 177605084 SBC5_LUNG 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
WLS p.V519L 1 68564392 68564392 SBC5_LUNG 37 Missense_Mutation SNP C G uc001dee.2 Hybrid_Cap... view
ZAK 2 174131511 174131512 SBC5_LUNG 37 3'UTR Ins - A rs75896701 uc002uhz.2 Hybrid_Cap...
ZNF217 p.P823L 20 52192835 52192835 SBC5_LUNG 37 Missense_Mutation SNP G A uc002xwq.3 ZNF217_uc010gij... Hybrid_Cap... view