Annotation Summary for Cell Line: SCC-15  

Cell line primary name: SCC-15
Cell line aliases:
Gender: M
Site Primary: upper_aerodigestive_tract
Histology: carcinoma
Hist Subtype1: squamous_cell_carcinoma
Notes:
Source: ATCC
Expression arrays: SILOS_p_NCLE_RNA9_HG-U133_Plus_2_A12_523608
SNP arrays: FIEFS_p_NCLE_DNA_Affy5_GenomeWideSNP_6_D12_411012
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in SCC-15

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ADAM17 2 9630245 9630245 SCC15_UPPER_AER... 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 SCC15_UPPER_AER... 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 SCC15_UPPER_AER... 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP9 p.1335_1336insQ 7 91652178 91652179 SCC15_UPPER_AER... 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 SCC15_UPPER_AER... 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ASPH p.A264_splice 8 62550924 62550925 SCC15_UPPER_AER... 37 Splice_Site_Ins Ins - A rs5891816 uc003xuj.2 ASPH_uc011leg.1... Hybrid_Cap...
ATR p.Y2637C 3 142168296 142168296 SCC15_UPPER_AER... 37 Missense_Mutation SNP T C uc003eux.3 XRN1_uc003eus.2... Hybrid_Cap... view
BCL11B p.E111K 14 99723904 99723904 SCC15_UPPER_AER... 37 Missense_Mutation SNP C T uc001yga.2 BCL11B_uc001ygb... Hybrid_Cap... view
CACNB2 10 18828721 18828722 SCC15_UPPER_AER... 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CDH1 p.N405S 16 68847292 68847292 SCC15_UPPER_AER... 37 Missense_Mutation SNP A G uc002ewg.1 CDH1_uc010vlj.1... Hybrid_Cap... view
CDH2 p.G839D 18 25532322 25532322 SCC15_UPPER_AER... 37 Missense_Mutation SNP C T uc002kwg.2 CDH2_uc010xbn.1... Hybrid_Cap... view
CDK11B 1 1654066 1654068 SCC15_UPPER_AER... 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CLK1 p.N324S 2 201721696 201721696 SCC15_UPPER_AER... 37 Missense_Mutation SNP T C uc010zhi.1 CLK1_uc002uwd.2... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 SCC15_UPPER_AER... 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CREB3L2 p.T100del 7 137612914 137612916 SCC15_UPPER_AER... 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CTBP2 p.K974fs 10 126678123 126678123 SCC15_UPPER_AER... 37 Frame_Shift_Del Del T - uc001lie.3 CTBP2_uc009yak.... Hybrid_Cap...
CXCL12 10 44873992 44873993 SCC15_UPPER_AER... 37 Intron Ins - CT rs117617571 uc001jbh.2 CXCL12_uc001jbf... Hybrid_Cap...
CYP3A4 p.K487fs 7 99355806 99355807 SCC15_UPPER_AER... 37 Frame_Shift_Ins Ins - T uc003urv.1 CYP3A4_uc003urw... Hybrid_Cap...
DACH1 13 72014625 72014626 SCC15_UPPER_AER... 37 3'UTR Ins - T rs117109529 uc010thn.1 DACH1_uc010tho.... Hybrid_Cap...
DDR2 1 162750211 162750212 SCC15_UPPER_AER... 37 3'UTR Del TT - uc001gcf.2 DDR2_uc001gcg.2... Hybrid_Cap...
DICER1 14 95599815 95599815 SCC15_UPPER_AER... 37 5'UTR SNP T C uc001ydw.2 DICER1_uc001ydv... Hybrid_Cap... view
DLL4 p.G625R 15 41229058 41229058 SCC15_UPPER_AER... 37 Missense_Mutation SNP G A uc001zng.1 Hybrid_Cap... view
EIF3A p.Y157C 10 120832473 120832473 SCC15_UPPER_AER... 37 Missense_Mutation SNP T C uc001ldu.2 EIF3A_uc010qsu.... Hybrid_Cap... view
EIF4E 4 99808137 99808141 SCC15_UPPER_AER... 37 Intron Del TTAAA - uc011ceb.1 EIF4E_uc011cea.... Hybrid_Cap...
EIF4G1 p.E306D 3 184039269 184039269 SCC15_UPPER_AER... 37 Missense_Mutation SNP A T uc010hxx.2 EIF4G1_uc003fno... Hybrid_Cap... view
EP300 22 41574970 41574972 SCC15_UPPER_AER... 37 3'UTR Del GTA - rs76489032 uc003azl.3 Hybrid_Cap...
EPHB2 p.G1023G 1 23240264 23240264 SCC15_UPPER_AER... 37 Silent SNP A G uc009vqj.1 EPHB2_uc001bge.... Hybrid_Cap... view
ERCC6 p.A211T 10 50736484 50736484 SCC15_UPPER_AER... 37 Missense_Mutation SNP C T uc001jhs.3 PGBD3_uc009xoe.... Hybrid_Cap... view
ERG p.A153T 21 39775584 39775584 SCC15_UPPER_AER... 37 Missense_Mutation SNP C T uc010gnw.2 ERG_uc002yxa.2_... Hybrid_Cap... view
FGFR3 4 1809128 1809129 SCC15_UPPER_AER... 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLI1 11 128638217 128638217 SCC15_UPPER_AER... 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLNA p.V1731V X 153583217 153583217 SCC15_UPPER_AER... 37 Silent SNP C T uc004fkk.2 FLNA_uc004fki.2... Hybrid_Cap... view
FMN2 p.PPLPGAGIPPP939del 1 240370914 240370946 SCC15_UPPER_AER... 37 In_Frame_Del Del GCCCC... - rs4997328;rs4997329 uc010pye.1 FMN2_uc010pyd.1... Hybrid_Cap...
FN1 2 216244182 216244185 SCC15_UPPER_AER... 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GPR112 p.D2657del X 135474445 135474447 SCC15_UPPER_AER... 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 SCC15_UPPER_AER... 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 SCC15_UPPER_AER... 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HIF1A 14 62213929 62213930 SCC15_UPPER_AER... 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HNF1A 12 121434630 121434631 SCC15_UPPER_AER... 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
ILK 11 6630029 6630029 SCC15_UPPER_AER... 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
INHBA 7 41729121 41729122 SCC15_UPPER_AER... 37 3'UTR Ins - T uc003thq.2 INHBA_uc003thr.... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 SCC15_UPPER_AER... 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KLK7 19 51480672 51480675 SCC15_UPPER_AER... 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
MAF 16 79628537 79628537 SCC15_UPPER_AER... 37 Intron Del T - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 SCC15_UPPER_AER... 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 SCC15_UPPER_AER... 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K6 p.Y751C 1 27686416 27686416 SCC15_UPPER_AER... 37 Missense_Mutation SNP T C uc001bny.1 MAP3K6_uc009vsw... Hybrid_Cap... view
MAPKAPK3 3 50685575 50685575 SCC15_UPPER_AER... 37 3'UTR Del A - rs76026164 uc003day.1 MAPKAPK3_uc003d... Hybrid_Cap...
MAPKBP1 15 42111753 42111754 SCC15_UPPER_AER... 37 Intron Ins - C rs3034891 uc001zok.3 MAPKBP1_uc001zo... Hybrid_Cap...
MCM3APAS 21 47671275 47671276 SCC15_UPPER_AER... 37 3'UTR Ins - AAT rs67797185 uc002zin.2 MCM3APAS_uc002z... Hybrid_Cap...
MLL3 p.Y816fs 7 151945071 151945072 SCC15_UPPER_AER... 37 Frame_Shift_Ins Ins - T uc003wla.2 Hybrid_Cap...
MYST4 p.EEEE1083del 10 76781852 76781863 SCC15_UPPER_AER... 37 In_Frame_Del Del GAGGA... - rs11001248 uc001jwn.1 MYST4_uc001jwm.... Hybrid_Cap...
NCAM1 11 112832307 112832308 SCC15_UPPER_AER... 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 SCC15_UPPER_AER... 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAPD3 p.Q1191_splice 11 134037889 134037892 SCC15_UPPER_AER... 37 Splice_Site_Del Del ACTT - uc001qhd.1 NCAPD3_uc010scm... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 SCC15_UPPER_AER... 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NFIA 1 61921185 61921186 SCC15_UPPER_AER... 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NPM1 5 170837734 170837734 SCC15_UPPER_AER... 37 3'UTR Del T - uc011dex.1 NPM1_uc003mbi.2... Hybrid_Cap...
NPR1 1 153665919 153665920 SCC15_UPPER_AER... 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 SCC15_UPPER_AER... 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NUP214 9 134067556 134067557 SCC15_UPPER_AER... 37 Intron Ins - T rs66652901 uc004cag.2 NUP214_uc004cah... Hybrid_Cap...
PDE4DIP p.S2089del 1 144859817 144859819 SCC15_UPPER_AER... 37 In_Frame_Del Del GGA - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PGR 11 100933598 100933599 SCC15_UPPER_AER... 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PIK3C2G p.P129del 12 18435399 18435401 SCC15_UPPER_AER... 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PIK3C2G 12 18800990 18800990 SCC15_UPPER_AER... 37 3'UTR Del A - rs16914368 uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PRKCA 17 64298959 64298960 SCC15_UPPER_AER... 37 5'UTR Ins - G rs71160558 uc002jfp.1 PRKCA_uc002jfo.... Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 SCC15_UPPER_AER... 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PTPRC p.S73C 1 198665964 198665964 SCC15_UPPER_AER... 37 Missense_Mutation SNP C G uc001gur.1 PTPRC_uc001gus.... Hybrid_Cap... view
RBPJ p.R238* 4 26426291 26426291 SCC15_UPPER_AER... 37 Nonsense_Mutation SNP C T rs5007634 uc003grx.1 RBPJ_uc003gry.1... Hybrid_Cap... view
RPS6KA5 14 91360733 91360734 SCC15_UPPER_AER... 37 Intron Ins - T rs77438853 uc001xys.2 RPS6KA5_uc010tw... Hybrid_Cap...
RUNX2 p.R338H 6 45480136 45480136 SCC15_UPPER_AER... 37 Missense_Mutation SNP G A uc011dvx.1 RUNX2_uc011dvy.... Hybrid_Cap... view
SLC6A8 X 152957656 152957657 SCC15_UPPER_AER... 37 Intron Ins - A uc004fib.3 SLC6A8_uc004fic... Hybrid_Cap...
SMAD2 p.S276L 18 45375016 45375016 SCC15_UPPER_AER... 37 Missense_Mutation SNP G A uc002lcy.2 SMAD2_uc002lcz.... Hybrid_Cap... view
STK25 2 242435659 242435662 SCC15_UPPER_AER... 37 Intron Del AAGG - rs3215138;rs75497042 uc002wbm.2 STK25_uc002wbk.... Hybrid_Cap...
STK31 7 23872024 23872025 SCC15_UPPER_AER... 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
STK32A 5 146619154 146619154 SCC15_UPPER_AER... 37 5'UTR SNP C A uc011dbw.1 STK32A_uc003lol... Hybrid_Cap... view
TLK1 2 171850178 171850179 SCC15_UPPER_AER... 37 3'UTR Ins - AA rs71008739 uc002ugo.2 TLK1_uc002ugn.2... Hybrid_Cap...
TMEM123 11 102269398 102269398 SCC15_UPPER_AER... 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TP53 p.E224_splice 17 7578176 7578176 SCC15_UPPER_AER... 37 Splice_Site_SNP SNP C T uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TRIM33 1 114940215 114940216 SCC15_UPPER_AER... 37 3'UTR Ins - G rs68133208 uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
VEGFC p.S419_splice 4 177605082 177605084 SCC15_UPPER_AER... 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
WEE1 11 9610239 9610239 SCC15_UPPER_AER... 37 3'UTR SNP C T uc001mhs.2 WEE1_uc001mht.2... Hybrid_Cap... view
ZAK p.L553del 2 174128577 174128579 SCC15_UPPER_AER... 37 In_Frame_Del Del ATT - uc002uhz.2 Hybrid_Cap...