Annotation Summary for Cell Line: SCC-25  

Cell line primary name: SCC-25
Cell line aliases:
Gender: M
Site Primary: upper_aerodigestive_tract
Histology: carcinoma
Hist Subtype1: squamous_cell_carcinoma
Notes:
Source: ATCC
Expression arrays: SILOS_p_NCLE_RNA9_HG-U133_Plus_2_A02_523514
SNP arrays: LOBBY_p_NCLE_DNAAffy6_GenomeWideSNP_6_B01_437296
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in SCC-25

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ADAM17 2 9630245 9630245 SCC25_UPPER_AER... 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 SCC25_UPPER_AER... 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 SCC25_UPPER_AER... 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 SCC25_UPPER_AER... 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ATP8B1 p.F312C 18 55362408 55362408 SCC25_UPPER_AER... 37 Missense_Mutation SNP A C uc002lgw.2 Hybrid_Cap... view
BIRC6 p.V333I 2 32620624 32620624 SCC25_UPPER_AER... 37 Missense_Mutation SNP G A uc010ezu.2 Hybrid_Cap... view
CHD9 p.2164_2165SS>S 16 53338410 53338412 SCC25_UPPER_AER... 37 In_Frame_Del Del TTC - uc002ehb.2 CHD9_uc002egy.2... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 SCC25_UPPER_AER... 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN6 3 1339681 1339686 SCC25_UPPER_AER... 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
CSMD3 8 114031240 114031240 SCC25_UPPER_AER... 37 Intron SNP T A uc003ynu.2 CSMD3_uc003ynt.... Hybrid_Cap... view
CTBP2 p.K974fs 10 126678123 126678123 SCC25_UPPER_AER... 37 Frame_Shift_Del Del T - uc001lie.3 CTBP2_uc009yak.... Hybrid_Cap...
DGKB p.A741V 7 14217680 14217680 SCC25_UPPER_AER... 37 Missense_Mutation SNP G A uc003ssz.2 DGKB_uc011jxt.1... Hybrid_Cap... view
DIP2C p.D194D 10 468786 468786 SCC25_UPPER_AER... 37 Silent SNP G A uc001ifp.2 DIP2C_uc009xhk.... Hybrid_Cap... view
EEF2K p.D584N 16 22278183 22278183 SCC25_UPPER_AER... 37 Missense_Mutation SNP G A uc002dki.2 EEF2K_uc002dkh.... Hybrid_Cap... view
EPHA6 3 97367230 97367231 SCC25_UPPER_AER... 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
EPHA8 p.R884C 1 22927502 22927502 SCC25_UPPER_AER... 37 Missense_Mutation SNP C T uc001bfx.1 Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 SCC25_UPPER_AER... 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FLI1 11 128638217 128638217 SCC25_UPPER_AER... 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FMN2 p.PPLPGAGIPPP939del 1 240370914 240370946 SCC25_UPPER_AER... 37 In_Frame_Del Del GCCCC... - rs4997328;rs4997329 uc010pye.1 FMN2_uc010pyd.1... Hybrid_Cap...
FOXP1 3 71008341 71008342 SCC25_UPPER_AER... 37 3'UTR Ins - T rs11433724;rs114233617 uc003dol.2 FOXP1_uc003dom.... Hybrid_Cap...
GNAQ 9 80336136 80336136 SCC25_UPPER_AER... 37 3'UTR SNP T C uc004akw.2 GNAQ_uc011lso.1... Hybrid_Cap... view
GPR112 p.D2657del X 135474445 135474447 SCC25_UPPER_AER... 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 SCC25_UPPER_AER... 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 SCC25_UPPER_AER... 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
ILK 11 6630029 6630029 SCC25_UPPER_AER... 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 SCC25_UPPER_AER... 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
LATS1 6 150023309 150023309 SCC25_UPPER_AER... 37 5'UTR SNP T G uc003qmu.1 LATS1_uc010kif.... Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 SCC25_UPPER_AER... 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 SCC25_UPPER_AER... 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 SCC25_UPPER_AER... 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MCM3AP 21 47679107 47679107 SCC25_UPPER_AER... 37 Intron SNP C T uc002zir.1 MCM3AP_uc002zip... Hybrid_Cap... view
MFSD4 p.L391V 1 205561289 205561289 SCC25_UPPER_AER... 37 Missense_Mutation SNP C G uc001hcv.3 MFSD4_uc010prk.... Hybrid_Cap... view
MLL3 p.Y816fs 7 151945071 151945072 SCC25_UPPER_AER... 37 Frame_Shift_Ins Ins - T uc003wla.2 Hybrid_Cap...
MYH11 16 15797783 15797787 SCC25_UPPER_AER... 37 3'UTR Del TTTTT - uc002ddx.2 MYH11_uc002ddv.... Hybrid_Cap...
MYST4 p.E1104del 10 76781906 76781908 SCC25_UPPER_AER... 37 In_Frame_Del Del GAA - rs79644703 uc001jwn.1 MYST4_uc001jwm.... Hybrid_Cap...
NCAM1 11 112832307 112832308 SCC25_UPPER_AER... 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 SCC25_UPPER_AER... 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA3 p.Q1276del 20 46279837 46279839 SCC25_UPPER_AER... 37 In_Frame_Del Del CAG - rs2664555 uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NOVA1 p.D47D 14 27064755 27064755 SCC25_UPPER_AER... 37 Silent SNP G A uc001wpy.2 NOVA1_uc001wpz.... Hybrid_Cap... view
NPR1 1 153665919 153665920 SCC25_UPPER_AER... 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 SCC25_UPPER_AER... 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
PAX3 2 223066017 223066018 SCC25_UPPER_AER... 37 Intron Ins - C rs115619343 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PIK3R4 p.E529_splice 3 130447530 130447531 SCC25_UPPER_AER... 37 Splice_Site_Ins Ins - A rs5852606 uc003enj.2 Hybrid_Cap...
PRDM16 1 3350424 3350424 SCC25_UPPER_AER... 37 3'UTR SNP G A uc001akf.2 PRDM16_uc001akc... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 SCC25_UPPER_AER... 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
RUNX1T1 p.P70A 8 93029505 93029505 SCC25_UPPER_AER... 37 Missense_Mutation SNP G C uc011lgi.1 RUNX1T1_uc003yf... Hybrid_Cap... view
STK31 7 23872024 23872025 SCC25_UPPER_AER... 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TAOK3 12 118588761 118588762 SCC25_UPPER_AER... 37 3'UTR Ins - T rs116872184 uc001twx.2 TAOK3_uc001twv.... Hybrid_Cap...
TLK2 p.R63W 17 60599598 60599598 SCC25_UPPER_AER... 37 Missense_Mutation SNP C T uc010ddp.2 TLK2_uc002izx.3... Hybrid_Cap... view
TNRC6B p.Q1328del 22 40697177 40697179 SCC25_UPPER_AER... 37 In_Frame_Del Del GCA - rs114291931 uc011aor.1 TNRC6B_uc003aym... Hybrid_Cap...
TP53 p.R209fs 17 7578222 7578223 SCC25_UPPER_AER... 37 Frame_Shift_Del Del TC - uc002gim.2 TP53_uc002gig.1... Hybrid_Cap...
TYRO3 p.S103_splice 15 41853509 41853509 SCC25_UPPER_AER... 37 Splice_Site_SNP SNP G C uc001zof.1 TYRO3_uc001zoe.... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 SCC25_UPPER_AER... 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
WEE1 p.Y362C 11 9598754 9598754 SCC25_UPPER_AER... 37 Missense_Mutation SNP A G uc001mhs.2 WEE1_uc001mht.2... Hybrid_Cap... view