Annotation Summary for Cell Line: SCC-9  

Cell line primary name: SCC-9
Cell line aliases:
Gender: M
Site Primary: upper_aerodigestive_tract
Histology: carcinoma
Hist Subtype1: squamous_cell_carcinoma
Notes:
Source: ATCC
Expression arrays: CASED_p_NCLE_RNA4_HG-U133_Plus_2_E11_383702
SNP arrays: BOWER_p_NCLE_DNAAffy8_GenomeWideSNP_6_B10_464586
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in SCC-9

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 SCC9_UPPER_AERO... 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
AATK p.S868* 17 79095133 79095133 SCC9_UPPER_AERO... 37 Nonsense_Mutation SNP G C uc010dia.2 AATK_uc010dhz.2... Hybrid_Cap... view
ACACA 17 35766564 35766564 SCC9_UPPER_AERO... 37 5'UTR Del A - uc002hno.2 ACACA_uc002hnn.... Hybrid_Cap...
ADAM17 2 9630245 9630245 SCC9_UPPER_AERO... 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 SCC9_UPPER_AERO... 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADCK1 14 78390632 78390637 SCC9_UPPER_AERO... 37 Intron Del AAACT... - rs78274857;rs74969652 uc001xui.2 ADCK1_uc010tvo.... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 SCC9_UPPER_AERO... 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP9 p.1335_1336insQ 7 91652178 91652179 SCC9_UPPER_AERO... 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ARID1A 1 27107263 27107264 SCC9_UPPER_AERO... 37 3'UTR Ins - C rs3841356 uc001bmv.1 ARID1A_uc001bmu... Hybrid_Cap...
ATP13A5 p.G780R 3 193029712 193029712 SCC9_UPPER_AERO... 37 Missense_Mutation SNP C T uc011bsq.1 Hybrid_Cap... view
ATP13A5 p.I537N 3 193042717 193042717 SCC9_UPPER_AERO... 37 Missense_Mutation SNP A T uc011bsq.1 Hybrid_Cap... view
ATR p.R1051H 3 142268340 142268340 SCC9_UPPER_AERO... 37 Missense_Mutation SNP C T uc003eux.3 Hybrid_Cap... view
AXL 19 41765973 41765992 SCC9_UPPER_AERO... 37 3'UTR Del GCAGT... - uc010ehj.2 CYP2F1_uc010xvw... Hybrid_Cap...
BCR 22 23631813 23631814 SCC9_UPPER_AERO... 37 Intron Ins - C rs66503844 uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BTG1 12 92537706 92537707 SCC9_UPPER_AERO... 37 3'UTR Ins - TT rs33983967 uc001tby.3 BTG1_uc001tbv.1... Hybrid_Cap...
CDK11B 1 1654066 1654068 SCC9_UPPER_AERO... 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CHD1 p.P1684del 5 98192165 98192167 SCC9_UPPER_AERO... 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CHIC2 4 54876132 54876132 SCC9_UPPER_AERO... 37 3'UTR Del C - rs4437313 uc003haj.1 PDGFRA_uc003haa... Hybrid_Cap...
CHRNA5 p.G464E 15 78885579 78885579 SCC9_UPPER_AERO... 37 Missense_Mutation SNP G A uc002bdy.2 CHRNA3_uc002bea... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 SCC9_UPPER_AERO... 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN6 3 1339681 1339686 SCC9_UPPER_AERO... 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
CTNNA2 2 80816295 80816295 SCC9_UPPER_AERO... 37 Intron SNP G A uc010ysh.1 CTNNA2_uc010yse... Hybrid_Cap... view
CXCL12 10 44873992 44873993 SCC9_UPPER_AERO... 37 Intron Ins - CT rs117617571 uc001jbh.2 CXCL12_uc001jbf... Hybrid_Cap...
CYP1B1 2 38297654 38297655 SCC9_UPPER_AERO... 37 3'UTR Ins - A rs9341258 uc002rqo.2 Hybrid_Cap...
DACH1 13 72014625 72014626 SCC9_UPPER_AERO... 37 3'UTR Ins - T rs117109529 uc010thn.1 DACH1_uc010tho.... Hybrid_Cap...
DDR2 1 162750211 162750212 SCC9_UPPER_AERO... 37 3'UTR Del TT - uc001gcf.2 DDR2_uc001gcg.2... Hybrid_Cap...
DFNA5 7 24783982 24783982 SCC9_UPPER_AERO... 37 Intron Del C - uc010kus.1 DFNA5_uc003swz.... Hybrid_Cap...
DYRK1A 21 38884966 38884967 SCC9_UPPER_AERO... 37 3'UTR Ins - T rs72430212 uc002ywk.2 DYRK1A_uc002ywi... Hybrid_Cap...
EDN1 6 12290729 12290729 SCC9_UPPER_AERO... 37 5'UTR Del A - uc003nae.3 EDN1_uc010jpb.2... Hybrid_Cap...
EIF4E 4 99808137 99808141 SCC9_UPPER_AERO... 37 Intron Del TTAAA - uc011ceb.1 EIF4E_uc011cea.... Hybrid_Cap...
EPHA6 3 97367230 97367231 SCC9_UPPER_AERO... 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
EXT1 8 118811807 118811807 SCC9_UPPER_AERO... 37 3'UTR Del T - uc003yok.1 Hybrid_Cap...
FGFR3 4 1809128 1809129 SCC9_UPPER_AERO... 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLCN p.A64V 17 17131261 17131261 SCC9_UPPER_AERO... 37 Missense_Mutation SNP G A uc002gra.3 PLD6_uc010cpn.2... Hybrid_Cap... view
FLI1 11 128638217 128638217 SCC9_UPPER_AERO... 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FN1 2 216244182 216244185 SCC9_UPPER_AERO... 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
FNBP1 9 132657927 132657927 SCC9_UPPER_AERO... 37 Intron SNP C A uc004byw.1 FNBP1_uc011mbv.... Hybrid_Cap... view
GRIA3 X 122318386 122318387 SCC9_UPPER_AERO... 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
HIF1A 14 62213929 62213930 SCC9_UPPER_AERO... 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HIPK4 p.F22S 19 40895745 40895745 SCC9_UPPER_AERO... 37 Missense_Mutation SNP A G uc002onp.2 Hybrid_Cap... view
HNF1A 12 121434630 121434631 SCC9_UPPER_AERO... 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
HRAS p.L133R 11 533505 533505 SCC9_UPPER_AERO... 37 Missense_Mutation SNP A C uc001lpv.2 HRAS_uc010qvw.1... Hybrid_Cap... view
ILK 11 6630029 6630029 SCC9_UPPER_AERO... 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITGA7 p.V828L 12 56087870 56087870 SCC9_UPPER_AERO... 37 Missense_Mutation SNP C A uc001shh.2 ITGA7_uc001shg.... Hybrid_Cap... view
ITPR2 p.R470_splice 12 26834804 26834805 SCC9_UPPER_AERO... 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KLK7 19 51480672 51480675 SCC9_UPPER_AERO... 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LRGUK p.H796Q 7 133948637 133948637 SCC9_UPPER_AERO... 37 Missense_Mutation SNP C G uc003vrm.1 Hybrid_Cap... view
LRP1B p.S3595L 2 141128839 141128839 SCC9_UPPER_AERO... 37 Missense_Mutation SNP G A uc002tvj.1 Hybrid_Cap... view
MAF 16 79628537 79628537 SCC9_UPPER_AERO... 37 Intron Del T - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAML2 p.604_607QQQQ>Q 11 95825375 95825383 SCC9_UPPER_AERO... 37 In_Frame_Del Del TGCTG... - rs113349418 uc001pfw.1 Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 SCC9_UPPER_AERO... 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 SCC9_UPPER_AERO... 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 SCC9_UPPER_AERO... 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAPK4 18 48190226 48190226 SCC9_UPPER_AERO... 37 5'UTR SNP G A uc002lev.2 MAPK4_uc010xdm.... Hybrid_Cap... view
MAPKAPK3 3 50685575 50685575 SCC9_UPPER_AERO... 37 3'UTR Del A - rs76026164 uc003day.1 MAPKAPK3_uc003d... Hybrid_Cap...
MCM3APAS 21 47671275 47671276 SCC9_UPPER_AERO... 37 3'UTR Ins - AAT rs67797185 uc002zin.2 MCM3APAS_uc002z... Hybrid_Cap...
MECOM p.V327_splice 3 168838998 168838998 SCC9_UPPER_AERO... 37 Splice_Site_SNP SNP C A uc011bpj.1 MECOM_uc010hwk.... Hybrid_Cap... view
MLL3 p.Y816fs 7 151945071 151945072 SCC9_UPPER_AERO... 37 Frame_Shift_Ins Ins - T uc003wla.2 Hybrid_Cap...
MN1 p.533_533Q>QQ 22 28194933 28194934 SCC9_UPPER_AERO... 37 In_Frame_Ins Ins - TGC rs45480998 uc003adj.2 Hybrid_Cap...
MYLK 3 123332876 123332876 SCC9_UPPER_AERO... 37 3'UTR Del T - rs115544676 uc003ego.2 MYLK_uc003egl.2... Hybrid_Cap...
MYLK p.E1430_splice 3 123368043 123368044 SCC9_UPPER_AERO... 37 Splice_Site_Ins Ins - G rs41431347 uc003ego.2 MYLK_uc010hrr.2... Hybrid_Cap...
NCAM1 11 112832307 112832308 SCC9_UPPER_AERO... 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 SCC9_UPPER_AERO... 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 SCC9_UPPER_AERO... 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NF1 p.E2600Q 17 29684037 29684037 SCC9_UPPER_AERO... 37 Missense_Mutation SNP G C uc002hgg.2 NF1_uc002hgh.2_... Hybrid_Cap... view
NFATC1 18 77287653 77287654 SCC9_UPPER_AERO... 37 3'UTR Del AA - uc010xfg.1 NFATC1_uc002lnd... Hybrid_Cap...
NFIA 1 61921185 61921186 SCC9_UPPER_AERO... 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NIN p.T22M 14 51288710 51288710 SCC9_UPPER_AERO... 37 Missense_Mutation SNP G A uc001wyi.2 NIN_uc001wyj.2_... Hybrid_Cap... view
NIPBL p.K565E 5 36984975 36984975 SCC9_UPPER_AERO... 37 Missense_Mutation SNP A G uc003jkl.3 NIPBL_uc003jkk.... Hybrid_Cap... view
NPM1 5 170837734 170837734 SCC9_UPPER_AERO... 37 3'UTR Del T - uc011dex.1 NPM1_uc003mbi.2... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 SCC9_UPPER_AERO... 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NSD1 p.G1589_splice 5 176683950 176683950 SCC9_UPPER_AERO... 37 Splice_Site_SNP SNP A T uc003mfr.3 NSD1_uc003mft.3... Hybrid_Cap... view
NSD1 p.G1656C 5 176684152 176684152 SCC9_UPPER_AERO... 37 Missense_Mutation SNP G T uc003mfr.3 NSD1_uc003mft.3... Hybrid_Cap... view
NUP214 9 134067556 134067557 SCC9_UPPER_AERO... 37 Intron Ins - T rs66652901 uc004cag.2 NUP214_uc004cah... Hybrid_Cap...
PAX3 2 223158653 223158653 SCC9_UPPER_AERO... 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PDE4DIP 1 144930802 144930802 SCC9_UPPER_AERO... 37 Intron SNP T A uc001elw.3 NBPF10_uc009wir... Hybrid_Cap... view
PGR 11 100933598 100933599 SCC9_UPPER_AERO... 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PLK4 p.P819S 4 128814929 128814929 SCC9_UPPER_AERO... 37 Missense_Mutation SNP C T uc003ifo.2 PLK4_uc011cgs.1... Hybrid_Cap... view
PMS2 p.G207E 7 6038824 6038824 SCC9_UPPER_AERO... 37 Missense_Mutation SNP C T uc003spl.2 PMS2_uc003spj.2... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 SCC9_UPPER_AERO... 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
RAG1 p.S601C 11 36596656 36596656 SCC9_UPPER_AERO... 37 Missense_Mutation SNP C G uc001mwu.3 RAG1_uc001mwt.2... Hybrid_Cap... view
RBPJ p.R238* 4 26426291 26426291 SCC9_UPPER_AERO... 37 Nonsense_Mutation SNP C T rs5007634 uc003grx.1 RBPJ_uc003gry.1... Hybrid_Cap... view
RECQL4 p.R766fs 8 145738768 145738768 SCC9_UPPER_AERO... 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RICTOR 5 38971880 38971882 SCC9_UPPER_AERO... 37 Intron Del TAA - uc003jlo.2 RICTOR_uc003jlp... Hybrid_Cap...
RPS6KA5 14 91360733 91360734 SCC9_UPPER_AERO... 37 Intron Ins - T rs77438853 uc001xys.2 RPS6KA5_uc010tw... Hybrid_Cap...
SGK494 p.QHTQQG10del 17 26941135 26941152 SCC9_UPPER_AERO... 37 In_Frame_Del Del CCCCT... - uc002hbr.1 SGK494_uc010waq... Hybrid_Cap...
SSX1 p.P116R X 48123233 48123233 SCC9_UPPER_AERO... 37 Missense_Mutation SNP C G uc004djb.1 Hybrid_Cap... view
STK31 7 23872024 23872025 SCC9_UPPER_AERO... 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
STK32C p.R259W 10 134039067 134039067 SCC9_UPPER_AERO... 37 Missense_Mutation SNP G A uc010quu.1 STK32C_uc001lld... Hybrid_Cap... view
STK38L 12 27450648 27450648 SCC9_UPPER_AERO... 37 5'UTR SNP G T uc001rhr.2 STK38L_uc001rhs... Hybrid_Cap... view
TEC 4 48139307 48139310 SCC9_UPPER_AERO... 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TLK1 2 171850178 171850179 SCC9_UPPER_AERO... 37 3'UTR Ins - AA rs71008739 uc002ugo.2 TLK1_uc002ugn.2... Hybrid_Cap...
TMEM123 11 102269398 102269398 SCC9_UPPER_AERO... 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TP53BP1 p.R1243C 15 43720315 43720315 SCC9_UPPER_AERO... 37 Missense_Mutation SNP G A uc001zrr.3 TP53BP1_uc010ud... Hybrid_Cap... view
TRPS1 8 116635872 116635873 SCC9_UPPER_AERO... 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
VEGFC p.S419_splice 4 177605082 177605084 SCC9_UPPER_AERO... 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...