Annotation Summary for Cell Line: SK-LU-1  

Cell line primary name: SK-LU-1
Cell line aliases:
Gender: F
Site Primary: lung
Histology: carcinoma
Hist Subtype1: adenocarcinoma
Notes:
Source: ATCC
Expression arrays: BRAKE_p_NCLE_RNA2_HG-U133_Plus_2_E06_241148
SNP arrays: ARLES_p_NCLE_DNAAffy2_S_GenomeWideSNP_6_G09_256162
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in SK-LU-1

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ABCC3 p.R269_splice 17 48736731 48736731 SKLU1_LUNG 37 Splice_Site_SNP SNP T C uc002isl.2 ABCC3_uc002isk.... Hybrid_Cap... view
ADAM17 2 9630245 9630245 SKLU1_LUNG 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 SKLU1_LUNG 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADAMTS2 5 178578136 178578136 SKLU1_LUNG 37 Intron SNP G C uc003mjw.2 ADAMTS2_uc011dg... Hybrid_Cap... view
ADCK1 14 78399743 78399743 SKLU1_LUNG 37 3'UTR SNP G C uc001xui.2 ADCK1_uc001xuj.... Hybrid_Cap... view
AKAP12 p.1531_1532insE 6 151674116 151674117 SKLU1_LUNG 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 SKLU1_LUNG 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
APC p.S1973C 5 112177208 112177208 SKLU1_LUNG 37 Missense_Mutation SNP A T uc010jby.2 APC_uc011cvt.1_... Hybrid_Cap... view
ARID1A p.G1251fs 1 27099874 27099874 SKLU1_LUNG 37 Frame_Shift_Del Del C - uc001bmv.1 ARID1A_uc001bmt... Hybrid_Cap...
ASTN1 p.S585L 1 176926947 176926947 SKLU1_LUNG 37 Missense_Mutation SNP G A uc001glc.2 ASTN1_uc001glb.... Hybrid_Cap... view
BRD2 6 32948599 32948599 SKLU1_LUNG 37 3'UTR Del C - uc010juh.2 BRD2_uc003ocn.3... Hybrid_Cap...
CABC1 1 227171585 227171585 SKLU1_LUNG 37 Intron Del T - uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CARD10 p.KE272del 22 37906309 37906314 SKLU1_LUNG 37 In_Frame_Del Del CTCCT... - uc003asx.1 CARD10_uc003ast... Hybrid_Cap...
CCNA1 13 37006632 37006632 SKLU1_LUNG 37 5'UTR SNP A G uc001uvr.3 CCNA1_uc010teo.... Hybrid_Cap... view
CDC73 1 193219931 193219931 SKLU1_LUNG 37 3'UTR SNP C A uc001gtb.2 Hybrid_Cap... view
CHD1 p.P1684del 5 98192165 98192167 SKLU1_LUNG 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 SKLU1_LUNG 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CLTCL1 22 19196673 19196674 SKLU1_LUNG 37 Intron Ins - A uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN1 p.R721K 12 41408078 41408078 SKLU1_LUNG 37 Missense_Mutation SNP G A uc001rmm.1 CNTN1_uc001rmn.... Hybrid_Cap... view
CREB3L2 p.T100del 7 137612914 137612916 SKLU1_LUNG 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CSMD3 p.S1486I 8 113563007 113563007 SKLU1_LUNG 37 Missense_Mutation SNP C A uc003ynu.2 CSMD3_uc003yns.... Hybrid_Cap... view
DCLK1 p.D593N 13 36382447 36382447 SKLU1_LUNG 37 Missense_Mutation SNP C T uc001uvf.2 DCLK1_uc001uve.... Hybrid_Cap... view
DNAH8 p.I3453N 6 38893877 38893877 SKLU1_LUNG 37 Missense_Mutation SNP T A uc003ooe.1 Hybrid_Cap... view
DNAH8 p.P4234S 6 38976726 38976726 SKLU1_LUNG 37 Missense_Mutation SNP C T uc003ooe.1 Hybrid_Cap... view
DST p.S2493P 6 56434698 56434698 SKLU1_LUNG 37 Missense_Mutation SNP A G uc003pdf.2 DST_uc003pcz.3_... Hybrid_Cap... view
DST p.Q1955E 6 56458967 56458967 SKLU1_LUNG 37 Missense_Mutation SNP G C uc003pdf.2 DST_uc003pcz.3_... Hybrid_Cap... view
DUSP6 p.E28K 12 89745735 89745735 SKLU1_LUNG 37 Missense_Mutation SNP C T uc001tay.2 DUSP6_uc001taz.... Hybrid_Cap... view
EIF2AK3 p.Y186H 2 88895064 88895064 SKLU1_LUNG 37 Missense_Mutation SNP A G uc002stc.3 Hybrid_Cap... view
EPHA6 p.E984K 3 97454784 97454784 SKLU1_LUNG 37 Missense_Mutation SNP G A uc010how.1 EPHA6_uc003drt.... Hybrid_Cap... view
EPHB1 p.P207S 3 134670708 134670708 SKLU1_LUNG 37 Missense_Mutation SNP C T uc003eqt.2 EPHB1_uc010htz.... Hybrid_Cap... view
EPHB4 p.G579R 7 100411295 100411295 SKLU1_LUNG 37 Missense_Mutation SNP C T uc003uwn.1 EPHB4_uc003uwm.... Hybrid_Cap... view
EPHB6 p.176_177insS 7 142562051 142562052 SKLU1_LUNG 37 In_Frame_Ins Ins - CCT rs72043374 uc011kst.1 EPHB6_uc011ksu.... Hybrid_Cap...
EXT1 8 118811807 118811807 SKLU1_LUNG 37 3'UTR Del T - uc003yok.1 Hybrid_Cap...
FAM123B p.P431Q X 63411875 63411875 SKLU1_LUNG 37 Missense_Mutation SNP G T uc004dvo.2 Hybrid_Cap... view
FAM132A 1 1177919 1177919 SKLU1_LUNG 37 3'UTR Del T - uc001adl.1 Hybrid_Cap...
FANCI p.L344del 15 89817450 89817452 SKLU1_LUNG 37 In_Frame_Del Del CTC - uc010bnp.1 FANCI_uc002bnm.... Hybrid_Cap...
FASN p.I95M 17 80051643 80051643 SKLU1_LUNG 37 Missense_Mutation SNP G C uc002kdu.2 Hybrid_Cap... view
FBN1 p.E740K 15 48789538 48789538 SKLU1_LUNG 37 Missense_Mutation SNP C T uc001zwx.1 Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 SKLU1_LUNG 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 SKLU1_LUNG 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLI1 11 128638217 128638217 SKLU1_LUNG 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLT4 p.A644V 5 180048631 180048631 SKLU1_LUNG 37 Missense_Mutation SNP G A uc003mlz.3 FLT4_uc003mma.3... Hybrid_Cap... view
FN1 2 216244182 216244185 SKLU1_LUNG 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GAK p.H646Y 4 870916 870916 SKLU1_LUNG 37 Missense_Mutation SNP G A uc003gbm.3 GAK_uc003gbn.3_... Hybrid_Cap... view
GLYATL2 11 58601858 58601858 SKLU1_LUNG 37 3'UTR Del T - uc001nnd.3 GLYATL2_uc009ym... Hybrid_Cap...
GRIA3 X 122318386 122318387 SKLU1_LUNG 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GRK4 p.E295K 4 3021509 3021509 SKLU1_LUNG 37 Missense_Mutation SNP G A uc003ggn.1 GRK4_uc003ggo.1... Hybrid_Cap... view
GUCY2C 12 14827464 14827466 SKLU1_LUNG 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HDAC3 p.R345C 5 141005278 141005278 SKLU1_LUNG 37 Missense_Mutation SNP G A uc003llf.2 HDAC3_uc003lle.... Hybrid_Cap... view
HEPH p.S218T X 65408218 65408218 SKLU1_LUNG 37 Missense_Mutation SNP T A uc011moz.1 HEPH_uc004dwn.2... Hybrid_Cap... view
HIF1A 14 62213929 62213930 SKLU1_LUNG 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HNF1A 12 121434630 121434631 SKLU1_LUNG 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
ICK p.Q298* 6 52878720 52878720 SKLU1_LUNG 37 Nonsense_Mutation SNP G A uc003pbh.2 ICK_uc003pbi.2_... Hybrid_Cap... view
ILK 11 6630029 6630029 SKLU1_LUNG 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
INHBA 7 41729121 41729122 SKLU1_LUNG 37 3'UTR Ins - T uc003thq.2 INHBA_uc003thr.... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 SKLU1_LUNG 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KDM6A p.Q729* X 44928929 44928929 SKLU1_LUNG 37 Nonsense_Mutation SNP C T uc011mkz.1 KDM6A_uc010nhk.... Hybrid_Cap... view
KIT 4 55604761 55604761 SKLU1_LUNG 37 3'UTR SNP C G uc010igr.2 KIT_uc010igs.2_... Hybrid_Cap... view
KLK7 19 51480672 51480675 SKLU1_LUNG 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
KRAS p.G12D 12 25398284 25398284 SKLU1_LUNG 37 Missense_Mutation SNP C T uc001rgp.1 KRAS_uc001rgq.1... Hybrid_Cap... view
LDHA 11 18428842 18428842 SKLU1_LUNG 37 3'UTR SNP C T uc010rdd.1 LDHA_uc001mok.3... Hybrid_Cap... view
LRP1 p.E2920Q 12 57589926 57589926 SKLU1_LUNG 37 Missense_Mutation SNP G C uc001snd.2 Hybrid_Cap... view
LRRK1 p.R1438C 15 101595408 101595408 SKLU1_LUNG 37 Missense_Mutation SNP C T uc002bwr.2 LRRK1_uc010usb.... Hybrid_Cap... view
LSP1 p.P147H 11 1901319 1901319 SKLU1_LUNG 37 Missense_Mutation SNP C A uc001luj.2 LSP1_uc001lui.2... Hybrid_Cap... view
LTBR p.P397T 12 6499984 6499984 SKLU1_LUNG 37 Missense_Mutation SNP C A uc001qny.1 LTBR_uc010sfc.1... Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 SKLU1_LUNG 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAML3 p.I628F 4 140810696 140810696 SKLU1_LUNG 37 Missense_Mutation SNP T A uc003ihz.1 MAML3_uc011chd.... Hybrid_Cap... view
MAP3K14 p.R218_splice 17 43364293 43364294 SKLU1_LUNG 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MCM3APAS 21 47671275 47671276 SKLU1_LUNG 37 3'UTR Ins - AAT rs67797185 uc002zin.2 MCM3APAS_uc002z... Hybrid_Cap...
MED13L 12 116399012 116399012 SKLU1_LUNG 37 3'UTR SNP C T uc001tvw.2 Hybrid_Cap... view
MLL3 p.F324L 7 151970830 151970830 SKLU1_LUNG 37 Missense_Mutation SNP G T uc003wla.2 Hybrid_Cap... view
MLLT1 p.E203Q 19 6222635 6222635 SKLU1_LUNG 37 Missense_Mutation SNP C G uc002mek.2 Hybrid_Cap... view
MTUS2 p.H762Y 13 29608070 29608070 SKLU1_LUNG 37 Missense_Mutation SNP C T uc001usl.3 Hybrid_Cap... view
MYO18B p.Q1968H 22 26348323 26348323 SKLU1_LUNG 37 Missense_Mutation SNP G T uc003abz.1 MYO18B_uc003aca... Hybrid_Cap... view
MYO3A p.Q382* 10 26357787 26357787 SKLU1_LUNG 37 Nonsense_Mutation SNP C T uc001isn.2 MYO3A_uc009xko.... Hybrid_Cap... view
NCAM1 11 112832307 112832308 SKLU1_LUNG 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 SKLU1_LUNG 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA3 p.Q1276del 20 46279864 46279866 SKLU1_LUNG 37 In_Frame_Del Del CAA - rs1132443;rs28529067 uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NIN 14 51190065 51190065 SKLU1_LUNG 37 3'UTR SNP A T uc001wyi.2 NIN_uc001wyj.2_... Hybrid_Cap... view
NIN p.E1911D 14 51204900 51204900 SKLU1_LUNG 37 Missense_Mutation SNP C G uc001wyi.2 NIN_uc001wyj.2_... Hybrid_Cap... view
NLRP10 p.L195V 11 7982576 7982576 SKLU1_LUNG 37 Missense_Mutation SNP G C uc001mfv.1 Hybrid_Cap... view
NUMA1 p.M2048I 11 71715125 71715125 SKLU1_LUNG 37 Missense_Mutation SNP C T uc001orl.1 IL18BP_uc009ysu... Hybrid_Cap... view
NUP133 p.S575F 1 229613376 229613376 SKLU1_LUNG 37 Missense_Mutation SNP G A uc001htn.2 Hybrid_Cap... view
OR2L13 1 248263675 248263675 SKLU1_LUNG 37 3'UTR SNP G A uc001ids.2 Hybrid_Cap... view
PAX3 2 223158653 223158653 SKLU1_LUNG 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PCDH15 p.Q396* 10 55955577 55955577 SKLU1_LUNG 37 Nonsense_Mutation SNP G A uc010qhy.1 PCDH15_uc010qhq... Hybrid_Cap... view
PCM1 8 17885407 17885408 SKLU1_LUNG 37 3'UTR Ins - T rs117750062 uc003wyi.3 PCM1_uc011kyh.1... Hybrid_Cap...
PDGFRA 4 55131002 55131002 SKLU1_LUNG 37 Intron Del A - uc003han.3 PDGFRA_uc003haa... Hybrid_Cap...
PGR 11 100933598 100933599 SKLU1_LUNG 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PKHD1 6 51483772 51483772 SKLU1_LUNG 37 3'UTR SNP C G uc003pah.1 Hybrid_Cap... view
POU5F1B 8 128429240 128429240 SKLU1_LUNG 37 3'UTR SNP G A uc003ysf.2 LOC727677_uc003... Hybrid_Cap... view
PRKCE p.E581K 2 46378189 46378189 SKLU1_LUNG 37 Missense_Mutation SNP G A uc002rut.2 Hybrid_Cap... view
PRKD3 2 37480319 37480320 SKLU1_LUNG 37 Stop_Codon_Ins Ins - T rs79875666 uc002rqd.2 Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 SKLU1_LUNG 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PTPRD p.P967Q 9 8485917 8485917 SKLU1_LUNG 37 Missense_Mutation SNP G T uc003zkk.2 PTPRD_uc003zkp.... Hybrid_Cap... view
PXDN p.R100G 2 1695746 1695746 SKLU1_LUNG 37 Missense_Mutation SNP T C uc002qxa.2 PXDN_uc002qxb.1... Hybrid_Cap... view
RAPGEF2 p.S1301C 4 160274932 160274932 SKLU1_LUNG 37 Missense_Mutation SNP C G uc003iqg.3 Hybrid_Cap... view
RASGRF1 15 79277150 79277151 SKLU1_LUNG 37 Intron Ins - C rs67045840;rs77640668 uc002beq.2 RASGRF1_uc002be... Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 SKLU1_LUNG 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RIMS2 p.A407V 8 104927796 104927796 SKLU1_LUNG 37 Missense_Mutation SNP C T uc003yls.2 RIMS2_uc003ylp.... Hybrid_Cap... view
ROBO2 p.D797H 3 77629146 77629146 SKLU1_LUNG 37 Missense_Mutation SNP G C uc003dpz.2 ROBO2_uc003dpy.... Hybrid_Cap... view
SCRIB p.P620H 8 144891035 144891035 SKLU1_LUNG 37 Missense_Mutation SNP G T uc003yzo.1 SCRIB_uc003yzp.... Hybrid_Cap... view
SEPT9 17 75494787 75494788 SKLU1_LUNG 37 3'UTR Ins - C rs5822173 uc002jts.3 SEPT9_uc010wtk.... Hybrid_Cap...
SLC6A8 X 152957656 152957657 SKLU1_LUNG 37 Intron Ins - A uc004fib.3 SLC6A8_uc004fic... Hybrid_Cap...
SOS1 p.R989_splice 2 39224180 39224180 SKLU1_LUNG 37 Splice_Site_SNP SNP C G uc002rrk.3 SOS1_uc002rrj.3... Hybrid_Cap... view
TAF1L p.D58H 9 32635406 32635406 SKLU1_LUNG 37 Missense_Mutation SNP C G uc003zrg.1 Hybrid_Cap... view
TMEM123 11 102269398 102269398 SKLU1_LUNG 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TMEM200A p.S282L 6 130762412 130762412 SKLU1_LUNG 37 Missense_Mutation SNP C T uc003qca.2 TMEM200A_uc010k... Hybrid_Cap... view
TNN p.S71L 1 175046766 175046766 SKLU1_LUNG 37 Missense_Mutation SNP C T uc001gkl.1 TNN_uc010pmx.1_... Hybrid_Cap... view
TP53 p.H193R 17 7578271 7578271 SKLU1_LUNG 37 Missense_Mutation SNP T C uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TRIM33 p.E938Q 1 114945462 114945462 SKLU1_LUNG 37 Missense_Mutation SNP C G uc001eew.2 TRIM33_uc010owr... Hybrid_Cap... view
TRPS1 8 116635872 116635873 SKLU1_LUNG 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TTN 2 179391639 179391640 SKLU1_LUNG 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.D30397H 2 179403769 179403769 SKLU1_LUNG 37 Missense_Mutation SNP C G uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.G27601V 2 179417121 179417121 SKLU1_LUNG 37 Missense_Mutation SNP C A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 SKLU1_LUNG 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
WNK1 p.S289P 12 922913 922913 SKLU1_LUNG 37 Missense_Mutation SNP T C uc001qio.3 WNK1_uc001qin.2... Hybrid_Cap... view
XPO5 p.Q1139P 6 43492270 43492270 SKLU1_LUNG 37 Missense_Mutation SNP T G uc003ovp.2 POLR1C_uc003ovo... Hybrid_Cap... view
ZNF423 p.R953Q 16 49670205 49670205 SKLU1_LUNG 37 Missense_Mutation SNP C T uc002efs.2 ZNF423_uc010vgn... Hybrid_Cap... view