Annotation Summary for Cell Line: SK-OV-3  

Cell line primary name: SK-OV-3
Cell line aliases:
Gender: F
Site Primary: ovary
Histology: carcinoma
Hist Subtype1: adenocarcinoma
Notes:
Source: ATCC
Expression arrays: CASED_p_NCLE_RNA4_HG-U133_Plus_2_A05_383732
SNP arrays: BOWER_p_NCLE_DNAAffy8_GenomeWideSNP_6_E07_464704
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in SK-OV-3

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ABL2 1 179086419 179086420 SKOV3_OVARY 37 Intron Ins - A rs72207641 uc001gmj.3 ABL2_uc010pnf.1... Hybrid_Cap...
ADAM17 2 9630245 9630245 SKOV3_OVARY 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 SKOV3_OVARY 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP9 p.1335_1336insQ 7 91652178 91652179 SKOV3_OVARY 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ALPK1 p.S194L 4 113346866 113346866 SKOV3_OVARY 37 Missense_Mutation SNP C T uc003iap.3 ALPK1_uc011cfw.... Hybrid_Cap... view
ARID1A p.Q586* 1 27058048 27058048 SKOV3_OVARY 37 Nonsense_Mutation SNP C T uc001bmv.1 ARID1A_uc001bmt... Hybrid_Cap... view
ATM p.D1413_splice 11 108160327 108160327 SKOV3_OVARY 37 Splice_Site_SNP SNP A G uc001pkb.1 ATM_uc009yxr.1_... Hybrid_Cap... view
AURKC 19 57742494 57742507 SKOV3_OVARY 37 5'UTR Del GGACG... - rs67926438;rs112039303;rs59094959 uc002qoe.2 AURKC_uc002qoc.... Hybrid_Cap...
BCL11B p.D885V 14 99640519 99640519 SKOV3_OVARY 37 Missense_Mutation SNP T A uc001yga.2 BCL11B_uc001ygb... Hybrid_Cap... view
BCL2A1 15 80259989 80259989 SKOV3_OVARY 37 Intron Del G - uc002bfc.3 BCL2A1_uc002bfd... Hybrid_Cap...
BIRC5 17 76219784 76219785 SKOV3_OVARY 37 3'UTR Ins - AA uc002jvf.2 BIRC5_uc002jvg.... Hybrid_Cap...
BMPR1B 4 96075907 96075907 SKOV3_OVARY 37 3'UTR SNP C G uc003htm.3 BMPR1B_uc010ilb... Hybrid_Cap... view
BTG1 12 92537706 92537707 SKOV3_OVARY 37 3'UTR Ins - T rs33983967 uc001tby.3 BTG1_uc001tbv.1... Hybrid_Cap...
CACNB2 10 18828721 18828722 SKOV3_OVARY 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CAMK2A 5 149602223 149602224 SKOV3_OVARY 37 3'UTR Del AC - uc003lrt.2 CAMK2A_uc003lrs... Hybrid_Cap...
CCL4 17 34432828 34432829 SKOV3_OVARY 37 3'UTR Ins - T uc002hkw.1 CCL4_uc002hkx.1... Hybrid_Cap...
CDK11B 1 1654066 1654068 SKOV3_OVARY 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CDK16 X 47088199 47088199 SKOV3_OVARY 37 3'UTR SNP T C uc011mll.1 CDK16_uc011mli.... Hybrid_Cap... view
CDK20 p.Q62R 9 90588841 90588841 SKOV3_OVARY 37 Missense_Mutation SNP T C uc004apr.2 CDK20_uc004aps.... Hybrid_Cap... view
CDX2 p.V285M 13 28537341 28537341 SKOV3_OVARY 37 Missense_Mutation SNP C T uc001urv.2 Hybrid_Cap... view
CHD1 p.P1684del 5 98192165 98192167 SKOV3_OVARY 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CHL1 3 447495 447495 SKOV3_OVARY 37 3'UTR SNP C T uc003bot.2 CHL1_uc003bou.2... Hybrid_Cap... view
CHUK p.I150fs 10 101980369 101980370 SKOV3_OVARY 37 Frame_Shift_Del Del TA - uc001kqp.2 Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 SKOV3_OVARY 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CPNE5 p.L96V 6 36767745 36767745 SKOV3_OVARY 37 Missense_Mutation SNP G C uc003omr.1 CPNE5_uc003oms.... Hybrid_Cap... view
CREB3L2 p.T100del 7 137612914 137612916 SKOV3_OVARY 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CSMD3 p.M3537T 8 113249436 113249436 SKOV3_OVARY 37 Missense_Mutation SNP A G uc003ynu.2 CSMD3_uc003yns.... Hybrid_Cap... view
CSMD3 p.N2862K 8 113308090 113308090 SKOV3_OVARY 37 Missense_Mutation SNP A T uc003ynu.2 CSMD3_uc003yns.... Hybrid_Cap... view
CSMD3 p.C1568Y 8 113529316 113529316 SKOV3_OVARY 37 Missense_Mutation SNP C T uc003ynu.2 CSMD3_uc003yns.... Hybrid_Cap... view
CSNK1G2 19 1980256 1980256 SKOV3_OVARY 37 3'UTR SNP A G uc002lul.3 CSNK1G2_uc010ds... Hybrid_Cap... view
DLL1 6 170597591 170597591 SKOV3_OVARY 37 Intron SNP G A uc003qxm.2 DLL1_uc011ehc.1... Hybrid_Cap... view
DST p.S3875C 6 56391308 56391308 SKOV3_OVARY 37 Missense_Mutation SNP T A uc003pdf.2 DST_uc003pcz.3_... Hybrid_Cap... view
DYRK1A 21 38884966 38884967 SKOV3_OVARY 37 3'UTR Ins - T rs72430212 uc002ywk.2 DYRK1A_uc002ywi... Hybrid_Cap...
EP300 p.Y1414C 22 41565575 41565575 SKOV3_OVARY 37 Missense_Mutation SNP A G uc003azl.3 Hybrid_Cap... view
EPHA6 3 97367230 97367231 SKOV3_OVARY 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
ERC1 p.Y747* 12 1299108 1299108 SKOV3_OVARY 37 Nonsense_Mutation SNP C G uc001qjb.2 ERC1_uc001qiz.2... Hybrid_Cap... view
ERN2 16 23712041 23712041 SKOV3_OVARY 37 Intron SNP C T uc002dma.3 ERN2_uc010bxp.2... Hybrid_Cap... view
FANCM p.A205V 14 45606377 45606377 SKOV3_OVARY 37 Missense_Mutation SNP C T uc001wwd.3 FANCM_uc001wwc.... Hybrid_Cap... view
FBLN5 p.R455Q 14 92336674 92336674 SKOV3_OVARY 37 Missense_Mutation SNP C T uc010aue.2 TC2N_uc001xzv.3... Hybrid_Cap... view
FBXW7 p.R505L 4 153247288 153247288 SKOV3_OVARY 37 Missense_Mutation SNP C A uc003ims.2 FBXW7_uc011cii.... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 SKOV3_OVARY 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FLI1 11 128638217 128638217 SKOV3_OVARY 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FMN2 p.R1454Q 1 240492680 240492680 SKOV3_OVARY 37 Missense_Mutation SNP G A uc010pye.1 FMN2_uc010pyd.1... Hybrid_Cap... view
FN1 2 216244182 216244185 SKOV3_OVARY 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
FN1 p.P1683S 2 216248054 216248054 SKOV3_OVARY 37 Missense_Mutation SNP G A uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap... view
GLTSCR1 p.A1264V 19 48204780 48204780 SKOV3_OVARY 37 Missense_Mutation SNP C T uc002phh.3 GLTSCR1_uc002ph... Hybrid_Cap... view
GPC3 X 132670099 132670099 SKOV3_OVARY 37 3'UTR SNP C T uc010nrn.1 GPC3_uc004exd.1... Hybrid_Cap... view
GPR112 p.D2657del X 135474445 135474447 SKOV3_OVARY 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GPR87 p.P11L 3 151017857 151017857 SKOV3_OVARY 37 Missense_Mutation SNP G A uc003eyt.2 MED12L_uc011bnz... Hybrid_Cap... view
GRAMD1B p.D121_splice 11 123465442 123465442 SKOV3_OVARY 37 Splice_Site_SNP SNP G C uc001pyw.2 GRAMD1B_uc001py... Hybrid_Cap... view
GRIA3 X 122318386 122318387 SKOV3_OVARY 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GRIK1 p.S339F 21 31015228 31015228 SKOV3_OVARY 37 Missense_Mutation SNP G A uc011acs.1 GRIK1_uc002ynn.... Hybrid_Cap... view
GSG2 p.G278E 17 3628062 3628062 SKOV3_OVARY 37 Missense_Mutation SNP G A uc002fwp.2 ITGAE_uc002fwo.... Hybrid_Cap... view
GUCY2F p.V297L X 108708514 108708514 SKOV3_OVARY 37 Missense_Mutation SNP C G uc004eod.3 GUCY2F_uc011msq... Hybrid_Cap... view
HDAC4 2 240048384 240048384 SKOV3_OVARY 37 Intron SNP T C uc002vyk.3 HDAC4_uc010fyz.... Hybrid_Cap... view
HERC2 p.A476V 15 28514413 28514413 SKOV3_OVARY 37 Missense_Mutation SNP G A uc001zbj.2 HERC2_uc001zbl.... Hybrid_Cap... view
HERC2 p.V177M 15 28525227 28525227 SKOV3_OVARY 37 Missense_Mutation SNP C T uc001zbj.2 HERC2_uc001zbl.... Hybrid_Cap... view
HIF1A 14 62213929 62213930 SKOV3_OVARY 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HMGA2 12 66345301 66345301 SKOV3_OVARY 37 3'UTR SNP G A uc001ssw.1 HMGA2_uc001ssx.... Hybrid_Cap... view
HSF1 p.N65I 8 145532668 145532668 SKOV3_OVARY 37 Missense_Mutation SNP A T uc003zbt.3 HSF1_uc003zbu.3... Hybrid_Cap... view
HSP90AB1 p.M617R 6 44220900 44220900 SKOV3_OVARY 37 Missense_Mutation SNP T G uc003oxa.1 HSP90AB1_uc011d... Hybrid_Cap... view
IL1R1 2 102792123 102792123 SKOV3_OVARY 37 Intron SNP C T uc002tbq.2 IL1R1_uc010fix.... Hybrid_Cap... view
IL1R1 2 102792195 102792195 SKOV3_OVARY 37 Intron SNP A G uc002tbq.2 IL1R1_uc010fix.... Hybrid_Cap... view
ILK 11 6630029 6630029 SKOV3_OVARY 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ING1 p.P390H 13 111372179 111372179 SKOV3_OVARY 37 Missense_Mutation SNP C A uc001vri.2 ING1_uc001vrf.2... Hybrid_Cap... view
INSRR p.D1139Y 1 156811569 156811569 SKOV3_OVARY 37 Missense_Mutation SNP C A uc010pht.1 NTRK1_uc001fqf.... Hybrid_Cap... view
KIAA2022 p.K397N X 73963201 73963201 SKOV3_OVARY 37 Missense_Mutation SNP C A uc004eby.2 Hybrid_Cap... view
KLK7 19 51480672 51480675 SKOV3_OVARY 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LIMK2 p.G499V 22 31669438 31669438 SKOV3_OVARY 37 Missense_Mutation SNP G T uc003akj.2 LIMK2_uc003akg.... Hybrid_Cap... view
LRP2 p.D3540N 2 170031853 170031853 SKOV3_OVARY 37 Missense_Mutation SNP C T uc002ues.2 Hybrid_Cap... view
LRP2 p.D3154H 2 170042398 170042398 SKOV3_OVARY 37 Missense_Mutation SNP C G uc002ues.2 Hybrid_Cap... view
MAF 16 79628609 79628610 SKOV3_OVARY 37 Intron Ins - A rs36052284 uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MALT1 p.K272fs 18 56376774 56376774 SKOV3_OVARY 37 Frame_Shift_Del Del A - uc002lhm.1 MALT1_uc002lhn.... Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 SKOV3_OVARY 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 SKOV3_OVARY 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 SKOV3_OVARY 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MASTL p.K65fs 10 27447484 27447484 SKOV3_OVARY 37 Frame_Shift_Del Del A - uc001itm.2 MASTL_uc001itl.... Hybrid_Cap...
MED13L p.T28M 12 116675500 116675500 SKOV3_OVARY 37 Missense_Mutation SNP G A uc001tvw.2 Hybrid_Cap... view
MYH11 p.A913T 16 15835463 15835463 SKOV3_OVARY 37 Missense_Mutation SNP C T uc002ddx.2 MYH11_uc002ddv.... Hybrid_Cap... view
NCAM1 11 112832307 112832308 SKOV3_OVARY 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 SKOV3_OVARY 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 p.A93V 11 113146105 113146105 SKOV3_OVARY 37 Missense_Mutation SNP C T uc001pnt.2 NCAM1_uc001pns.... Hybrid_Cap... view
NCOA1 p.E1242K 2 24974868 24974868 SKOV3_OVARY 37 Missense_Mutation SNP G A uc002rfk.2 NCOA1_uc010eye.... Hybrid_Cap... view
NCOA3 p.Y319D 20 46262371 46262371 SKOV3_OVARY 37 Missense_Mutation SNP T G uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap... view
NEK3 p.M53V 13 52730233 52730233 SKOV3_OVARY 37 Missense_Mutation SNP T C uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap... view
NF1 p.G1702C 17 29653106 29653106 SKOV3_OVARY 37 Missense_Mutation SNP G T uc002hgg.2 NF1_uc002hgh.2_... Hybrid_Cap... view
NFATC1 18 77287653 77287654 SKOV3_OVARY 37 3'UTR Del AA - uc010xfg.1 NFATC1_uc002lnd... Hybrid_Cap...
NLRP3 1 247611982 247611982 SKOV3_OVARY 37 3'UTR Del C - uc001icr.2 NLRP3_uc001ics.... Hybrid_Cap...
NOTCH2 p.R1604fs 1 120466308 120466309 SKOV3_OVARY 37 Frame_Shift_Del Del CT - uc001eik.2 Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 SKOV3_OVARY 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NUP210 p.M538T 3 13413507 13413507 SKOV3_OVARY 37 Missense_Mutation SNP A G uc003bxv.1 NUP210_uc003bxx... Hybrid_Cap... view
PAX3 2 223066017 223066018 SKOV3_OVARY 37 Intron Ins - C rs115619343 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAX3 2 223158653 223158653 SKOV3_OVARY 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PDGFRA 4 55130162 55130162 SKOV3_OVARY 37 Intron Del T - uc003han.3 PDGFRA_uc003haa... Hybrid_Cap...
PGR 11 100933598 100933599 SKOV3_OVARY 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PHF3 p.L1573* 6 64422202 64422202 SKOV3_OVARY 37 Nonsense_Mutation SNP T A uc003pep.1 PHF3_uc003pen.2... Hybrid_Cap... view
PHIP p.D1684V 6 79650825 79650825 SKOV3_OVARY 37 Missense_Mutation SNP T A uc003pir.2 PHIP_uc003piq.2... Hybrid_Cap... view
PIK3CA p.H1047R 3 178952085 178952085 SKOV3_OVARY 37 Missense_Mutation SNP A G uc003fjk.2 Hybrid_Cap... view
PKDCC 2 42284932 42284932 SKOV3_OVARY 37 3'UTR SNP C T uc002rsg.2 Hybrid_Cap... view
PLK1 p.K474E 16 23700708 23700708 SKOV3_OVARY 37 Missense_Mutation SNP A G uc002dlz.1 Hybrid_Cap... view
PSKH1 p.R151H 16 67943104 67943104 SKOV3_OVARY 37 Missense_Mutation SNP G A uc002euv.2 PSKH1_uc010cet.... Hybrid_Cap... view
RASGRF1 p.V552fs 15 79310201 79310201 SKOV3_OVARY 37 Frame_Shift_Del Del C - uc002beq.2 RASGRF1_uc002be... Hybrid_Cap...
RBL1 20 35632029 35632030 SKOV3_OVARY 37 Intron Del AA - uc002xgi.2 RBL1_uc010zvt.1... Hybrid_Cap...
RBPJ p.K82fs 4 26417146 26417146 SKOV3_OVARY 37 Frame_Shift_Del Del A - uc003grx.1 RBPJ_uc003gry.1... Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 SKOV3_OVARY 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
ROS1 p.L139V 6 117725466 117725466 SKOV3_OVARY 37 Missense_Mutation SNP G C uc003pxp.1 ROS1_uc011ebi.1... Hybrid_Cap... view
SNRK p.S599T 3 43389547 43389547 SKOV3_OVARY 37 Missense_Mutation SNP G C uc003cms.3 SNRK_uc003cmt.3... Hybrid_Cap... view
STRADB 2 202344919 202344919 SKOV3_OVARY 37 3'UTR SNP T G uc002uyd.3 Hybrid_Cap... view
TFG 3 100432487 100432487 SKOV3_OVARY 37 5'UTR SNP T G uc003due.2 TFG_uc003duf.2_... Hybrid_Cap... view
TFRC 3 195778752 195778752 SKOV3_OVARY 37 3'UTR SNP T C uc003fvz.3 TFRC_uc003fwa.3... Hybrid_Cap... view
TGFB2 1 218519928 218519929 SKOV3_OVARY 37 5'UTR Ins - AAAC uc001hln.2 TGFB2_uc001hll.... Hybrid_Cap...
TLK1 2 171850178 171850179 SKOV3_OVARY 37 3'UTR Ins - AA rs71008739 uc002ugo.2 TLK1_uc002ugn.2... Hybrid_Cap...
TLN1 p.D1852N 9 35705806 35705806 SKOV3_OVARY 37 Missense_Mutation SNP C T uc003zxt.2 Hybrid_Cap... view
TP63 p.E33Q 3 189455563 189455563 SKOV3_OVARY 37 Missense_Mutation SNP G C uc003fry.2 TP63_uc003frx.2... Hybrid_Cap... view
TP63 3 189507518 189507519 SKOV3_OVARY 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TP63 p.S560A 3 189608603 189608603 SKOV3_OVARY 37 Missense_Mutation SNP T G uc003fry.2 TP63_uc003frz.2... Hybrid_Cap... view
TRIB2 p.G169fs 2 12863620 12863620 SKOV3_OVARY 37 Frame_Shift_Del Del G - uc002rbv.3 TRIB2_uc010yjp.... Hybrid_Cap...
TRIM33 1 114940215 114940216 SKOV3_OVARY 37 3'UTR Ins - G rs68133208 uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TRPS1 8 116635872 116635873 SKOV3_OVARY 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TTN p.V10609_splice 2 179517075 179517075 SKOV3_OVARY 37 Splice_Site_SNP SNP C T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
UNC13C p.S561P 15 54306781 54306781 SKOV3_OVARY 37 Missense_Mutation SNP T C uc002ack.2 Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 SKOV3_OVARY 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
WNK1 p.P1061Q 12 990928 990928 SKOV3_OVARY 37 Missense_Mutation SNP C A uc001qio.3 WNK1_uc001qip.3... Hybrid_Cap... view
YES1 18 724362 724362 SKOV3_OVARY 37 3'UTR SNP G C uc002kky.2 YES1_uc002kkz.2... Hybrid_Cap... view