Annotation Summary for Cell Line: SNU-398  

Cell line primary name: SNU-398
Cell line aliases: NCI-SNU-398
Gender: M
Site Primary: liver
Histology: carcinoma
Hist Subtype1: hepatocellular_carcinoma
Notes:
Source: ATCC
Expression arrays: CASED_p_NCLE_RNA4_HG-U133_Plus_2_G05_383642
SNP arrays: LOBBY_p_NCLE_DNAAffy6_GenomeWideSNP_6_B07_437308
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in SNU-398

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 SNU398_LIVER 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ACVR1B 12 52380975 52380978 SNU398_LIVER 37 Intron Del AAAC - uc010snn.1 ACVR1B_uc001rzl... Hybrid_Cap...
ADAM28 8 24211994 24211997 SNU398_LIVER 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADAMTS20 p.I289M 12 43895955 43895955 SNU398_LIVER 37 Missense_Mutation SNP A C uc010skx.1 Hybrid_Cap... view
AKAP12 p.1531_1532insE 6 151674116 151674117 SNU398_LIVER 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ALPK1 4 113347609 113347610 SNU398_LIVER 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
ARNT p.P706L 1 150785811 150785811 SNU398_LIVER 37 Missense_Mutation SNP G A rs2275237 uc001evr.1 ARNT_uc010pck.1... Hybrid_Cap... view
ASTN1 p.V79A 1 177133577 177133577 SNU398_LIVER 37 Missense_Mutation SNP A G uc001glc.2 ASTN1_uc001glb.... Hybrid_Cap... view
AURKC 19 57742494 57742507 SNU398_LIVER 37 5'UTR Del GGACG... - rs67926438;rs112039303;rs59094959 uc002qoe.2 AURKC_uc002qoc.... Hybrid_Cap...
BCL3 19 45262965 45262965 SNU398_LIVER 37 3'UTR Del C - uc010xxe.1 Hybrid_Cap...
BRCA2 p.R2973C 13 32953616 32953616 SNU398_LIVER 37 Missense_Mutation SNP C T rs45469092 uc001uub.1 Hybrid_Cap... view
BRD4 19 15349135 15349135 SNU398_LIVER 37 3'UTR SNP T G uc002nar.2 Hybrid_Cap... view
CACNB2 10 18828721 18828722 SNU398_LIVER 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CARD10 p.KE272del 22 37906309 37906314 SNU398_LIVER 37 In_Frame_Del Del CTCCT... - uc003asx.1 CARD10_uc003ast... Hybrid_Cap...
CDK11B 1 1654066 1654068 SNU398_LIVER 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CHD8 14 21853630 21853630 SNU398_LIVER 37 3'UTR Del T - rs78520772 uc001was.1 CHD8_uc001war.1... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 SNU398_LIVER 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CREB3L2 p.T100del 7 137612914 137612916 SNU398_LIVER 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CTNNB1 p.S37C 3 41266113 41266113 SNU398_LIVER 37 Missense_Mutation SNP C G uc010hia.1 CTNNB1_uc003ckp... Hybrid_Cap... view
CYP1B1 2 38297654 38297655 SNU398_LIVER 37 3'UTR Ins - A rs9341258 uc002rqo.2 Hybrid_Cap...
DACH1 13 72014625 72014626 SNU398_LIVER 37 3'UTR Ins - T rs117109529 uc010thn.1 DACH1_uc010tho.... Hybrid_Cap...
DGKB 7 14216345 14216346 SNU398_LIVER 37 Intron Ins - AGACT uc003ssz.2 DGKB_uc011jxt.1... Hybrid_Cap...
DMPK 19 46273643 46273643 SNU398_LIVER 37 3'UTR SNP T A uc002pdi.1 SIX5_uc002pdb.2... Hybrid_Cap... view
DPYD p.Y304H 1 98060663 98060663 SNU398_LIVER 37 Missense_Mutation SNP A G uc001drv.2 Hybrid_Cap... view
DST p.H2425R 6 56436988 56436988 SNU398_LIVER 37 Missense_Mutation SNP T C uc003pdf.2 DST_uc003pcz.3_... Hybrid_Cap... view
EIF3A 10 120795546 120795546 SNU398_LIVER 37 3'UTR SNP G A uc001ldu.2 EIF3A_uc010qsu.... Hybrid_Cap... view
EML4 p.L970R 2 42557310 42557310 SNU398_LIVER 37 Missense_Mutation SNP T G uc002rsi.2 EML4_uc010fap.2... Hybrid_Cap... view
EPHA6 3 97367230 97367231 SNU398_LIVER 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
ESR1 p.D232fs 6 152201836 152201836 SNU398_LIVER 37 Frame_Shift_Del Del T - uc010kio.2 ESR1_uc003qom.3... Hybrid_Cap...
ETV1 7 14028708 14028708 SNU398_LIVER 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FGFR1OP 6 167453519 167453520 SNU398_LIVER 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 SNU398_LIVER 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLT4 p.H1291N 5 180035990 180035990 SNU398_LIVER 37 Missense_Mutation SNP G T uc003mlz.3 FLT4_uc003mma.3... Hybrid_Cap... view
FN1 2 216244182 216244185 SNU398_LIVER 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
FOXP1 3 71008341 71008342 SNU398_LIVER 37 3'UTR Ins - T rs11433724;rs114233617 uc003dol.2 FOXP1_uc003dom.... Hybrid_Cap...
GCNT2 p.G350E 6 10626680 10626680 SNU398_LIVER 37 Missense_Mutation SNP G A rs56141211 uc010joo.2 GCNT2_uc010jol.... Hybrid_Cap... view
GLI3 p.T615S 7 42012196 42012196 SNU398_LIVER 37 Missense_Mutation SNP T A uc011kbh.1 GLI3_uc011kbg.1... Hybrid_Cap... view
GPR112 p.D2657del X 135474445 135474447 SNU398_LIVER 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 SNU398_LIVER 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GTSE1 p.L723V 22 46725974 46725974 SNU398_LIVER 37 Missense_Mutation SNP C G uc011aqy.1 GTSE1_uc011aqz.... Hybrid_Cap... view
GUCY2C 12 14827464 14827466 SNU398_LIVER 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HNF1A 12 121434630 121434631 SNU398_LIVER 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
IL17RD p.K72K 3 57148814 57148814 SNU398_LIVER 37 Silent SNP C T uc003dil.2 IL17RD_uc003dik... Hybrid_Cap... view
ILK 11 6630029 6630029 SNU398_LIVER 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITGB1 10 33197131 33197134 SNU398_LIVER 37 Intron Del CTTT - rs116966876 uc001iwq.3 ITGB1_uc001iwp.... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 SNU398_LIVER 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
LEMD1 1 205350658 205350658 SNU398_LIVER 37 3'UTR SNP C T uc001hci.1 LEMD1_uc001hcj.... Hybrid_Cap... view
LMO2 p.I92V 11 33886338 33886338 SNU398_LIVER 37 Missense_Mutation SNP T C uc010rem.1 LMO2_uc001mvc.2... Hybrid_Cap... view
LSP1 p.D169Y 11 1901384 1901384 SNU398_LIVER 37 Missense_Mutation SNP G T uc001luj.2 LSP1_uc001lui.2... Hybrid_Cap... view
MAF 16 79628537 79628537 SNU398_LIVER 37 Intron Del T - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 SNU398_LIVER 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP2K1 15 66679649 66679650 SNU398_LIVER 37 5'UTR Ins - C rs67229745 uc010bhq.2 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 SNU398_LIVER 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MECOM p.G1143R 3 168806946 168806946 SNU398_LIVER 37 Missense_Mutation SNP C T uc011bpj.1 MECOM_uc010hwk.... Hybrid_Cap... view
MED13L p.V1444I 12 116424079 116424079 SNU398_LIVER 37 Missense_Mutation SNP C T uc001tvw.2 Hybrid_Cap... view
MYB p.T212I 6 135513569 135513569 SNU398_LIVER 37 Missense_Mutation SNP C T uc003qfh.2 MYB_uc003qfc.2_... Hybrid_Cap... view
MYLK3 p.D435H 16 46766279 46766279 SNU398_LIVER 37 Missense_Mutation SNP C G uc002eei.3 MYLK3_uc010vge.... Hybrid_Cap... view
NCAM1 11 112832307 112832308 SNU398_LIVER 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 SNU398_LIVER 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 SNU398_LIVER 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NLRP3 p.I297M 1 247587636 247587636 SNU398_LIVER 37 Missense_Mutation SNP C G uc001icr.2 NLRP3_uc001ics.... Hybrid_Cap... view
NLRP3 p.L701H 1 247588847 247588847 SNU398_LIVER 37 Missense_Mutation SNP T A rs104895415 uc001icr.2 NLRP3_uc001ics.... Hybrid_Cap... view
NOTCH4 6 32170465 32170465 SNU398_LIVER 37 Intron Del G - uc003obb.2 NOTCH4_uc003oba... Hybrid_Cap...
NPM1 5 170837734 170837734 SNU398_LIVER 37 3'UTR Del T - uc011dex.1 NPM1_uc003mbi.2... Hybrid_Cap...
NPR1 1 153665919 153665920 SNU398_LIVER 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 SNU398_LIVER 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 SNU398_LIVER 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NR4A3 p.A17T 9 102590340 102590340 SNU398_LIVER 37 Missense_Mutation SNP G A uc004bai.2 NR4A3_uc004bae.... Hybrid_Cap... view
NTRK1 p.D738N 1 156851255 156851255 SNU398_LIVER 37 Missense_Mutation SNP G A uc001fqh.1 NTRK1_uc001fqf.... Hybrid_Cap... view
NUP133 1 229577475 229577475 SNU398_LIVER 37 3'UTR SNP T C uc001htn.2 Hybrid_Cap... view
NUP98 11 3697276 3697276 SNU398_LIVER 37 3'UTR SNP G A uc001lyh.2 NUP98_uc001lyi.... Hybrid_Cap... view
NYNRIN p.S297R 14 24877889 24877889 SNU398_LIVER 37 Missense_Mutation SNP A C uc001wpf.3 Hybrid_Cap... view
PAX3 2 223158653 223158653 SNU398_LIVER 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAXIP1 p.A221T 7 154767819 154767819 SNU398_LIVER 37 Missense_Mutation SNP C T uc003wlp.2 PAXIP1_uc003wlq... Hybrid_Cap... view
PDCD11 p.H880Y 10 105182885 105182885 SNU398_LIVER 37 Missense_Mutation SNP C T uc001kwy.1 Hybrid_Cap... view
PDE4DIP 1 144863531 144863531 SNU398_LIVER 37 Intron SNP G A uc001elw.3 NBPF10_uc009wir... Hybrid_Cap... view
PDK4 7 95221928 95221928 SNU398_LIVER 37 Intron Del A - uc003uoa.2 PDK4_uc003unz.2... Hybrid_Cap...
PER1 p.D372N 17 8051512 8051512 SNU398_LIVER 37 Missense_Mutation SNP C T uc002gkd.2 PER1_uc010vuq.1... Hybrid_Cap... view
PGR 11 100933598 100933599 SNU398_LIVER 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PIK3C2G p.P129del 12 18435399 18435401 SNU398_LIVER 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PIK3C2G 12 18800990 18800990 SNU398_LIVER 37 3'UTR Del A - rs16914368 uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PLCG1 p.E758K 20 39795470 39795470 SNU398_LIVER 37 Missense_Mutation SNP G A uc002xjo.1 PLCG1_uc002xjp.... Hybrid_Cap... view
PRKCA 17 64298959 64298960 SNU398_LIVER 37 5'UTR Ins - G rs71160558 uc002jfp.1 PRKCA_uc002jfo.... Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 SNU398_LIVER 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
RBPJ 4 26431822 26431822 SNU398_LIVER 37 Intron Del A - rs76214390 uc003grx.1 RBPJ_uc003gry.1... Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 SNU398_LIVER 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RHPN2 p.T120T 19 33512507 33512507 SNU398_LIVER 37 Silent SNP C T uc002nuf.2 RHPN2_uc010xro.... Hybrid_Cap... view
ROBO2 3 77695399 77695399 SNU398_LIVER 37 3'UTR SNP C A uc003dpz.2 ROBO2_uc003dpy.... Hybrid_Cap... view
RPS6KA5 14 91360733 91360734 SNU398_LIVER 37 Intron Ins - T rs77438853 uc001xys.2 RPS6KA5_uc010tw... Hybrid_Cap...
SEPT9 17 75494787 75494788 SNU398_LIVER 37 3'UTR Ins - C rs5822173 uc002jts.3 SEPT9_uc010wtk.... Hybrid_Cap...
SGK269 15 77406377 77406377 SNU398_LIVER 37 3'UTR SNP G A uc002bcm.2 Hybrid_Cap... view
SLCO4A1 p.P494P 20 61299106 61299106 SNU398_LIVER 37 Silent SNP C T uc002ydb.1 SLCO4A1_uc002yd... Hybrid_Cap... view
SS18L1 20 60754484 60754488 SNU398_LIVER 37 3'UTR Del GTATT - uc002ycb.2 SS18L1_uc002ybz... Hybrid_Cap...
STK24 p.D104N 13 99134575 99134575 SNU398_LIVER 37 Missense_Mutation SNP C T uc001vnm.1 STK24_uc001vnn.... Hybrid_Cap... view
STK25 2 242435680 242435680 SNU398_LIVER 37 Intron SNP C T uc002wbm.2 STK25_uc002wbk.... Hybrid_Cap... view
STK31 7 23872024 23872025 SNU398_LIVER 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TEC 4 48139307 48139310 SNU398_LIVER 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TLK1 2 171850178 171850179 SNU398_LIVER 37 3'UTR Ins - AA rs71008739 uc002ugo.2 TLK1_uc002ugn.2... Hybrid_Cap...
TMEM123 11 102269398 102269398 SNU398_LIVER 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TNFSF11 13 43181212 43181212 SNU398_LIVER 37 3'UTR SNP C T uc001uyu.2 TNFSF11_uc001uy... Hybrid_Cap... view
TOP2B p.D1613H 3 25639827 25639827 SNU398_LIVER 37 Missense_Mutation SNP C G uc003cdj.2 TOP2B_uc011awm.... Hybrid_Cap... view
TP63 3 189507518 189507519 SNU398_LIVER 37 Intron Ins - AG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TRIM28 p.P814L 19 59061853 59061853 SNU398_LIVER 37 Missense_Mutation SNP C T uc002qtg.1 TRIM28_uc010eut... Hybrid_Cap... view
TRIP11 p.M1690L 14 92460245 92460245 SNU398_LIVER 37 Missense_Mutation SNP T A uc001xzy.2 TRIP11_uc010auf... Hybrid_Cap... view
TTBK1 p.E771del 6 43250726 43250728 SNU398_LIVER 37 In_Frame_Del Del GAA - uc003ouq.1 Hybrid_Cap...
TTN 2 179391639 179391640 SNU398_LIVER 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
VEGFC p.S419_splice 4 177605082 177605084 SNU398_LIVER 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
WDHD1 p.N73S 14 55477150 55477150 SNU398_LIVER 37 Missense_Mutation SNP T C uc001xbm.1 WDHD1_uc001xbn.... Hybrid_Cap... view
WEE2 p.I345T 7 141423747 141423747 SNU398_LIVER 37 Missense_Mutation SNP T C uc003vwn.2 FLJ40852_uc011k... Hybrid_Cap... view
ZNF521 p.P516S 18 22806336 22806336 SNU398_LIVER 37 Missense_Mutation SNP G A rs114749105 uc002kvk.2 ZNF521_uc010xbe... Hybrid_Cap... view