Annotation Summary for Cell Line: SU-DHL-4  

Cell line primary name: SU-DHL-4
Cell line aliases:
Gender: M
Site Primary: haematopoietic_and_lymphoid_tissue
Histology: lymphoid_neoplasm
Hist Subtype1: diffuse_large_B_cell_lymphoma
Notes:
Source: DSMZ
Expression arrays: SILOS_p_NCLE_RNA9_HG-U133_Plus_2_E04_523644
SNP arrays: AWASH_p_NCLE_DNAAffy10_GenomeWideSNP_6_D01_542858
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in SU-DHL-4

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 SUDHL4_HAEMATOP... 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
AATK p.1331_1332insTP 17 79093270 79093271 SUDHL4_HAEMATOP... 37 In_Frame_Ins Ins - GGGCGT rs55713566 uc010dia.2 AATK_uc010dhz.2... Hybrid_Cap...
ACACA p.R745Q 17 35605010 35605010 SUDHL4_HAEMATOP... 37 Missense_Mutation SNP C T uc002hno.2 ACACA_uc002hnk.... Hybrid_Cap... view
ADAM17 2 9630245 9630245 SUDHL4_HAEMATOP... 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 SUDHL4_HAEMATOP... 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP9 p.1335_1336insQ 7 91652178 91652179 SUDHL4_HAEMATOP... 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 SUDHL4_HAEMATOP... 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ALS2 p.E1592K 2 202569241 202569241 SUDHL4_HAEMATOP... 37 Missense_Mutation SNP C T uc002uyo.2 ALS2_uc010ftl.2... Hybrid_Cap... view
ARAF X 47430973 47430973 SUDHL4_HAEMATOP... 37 3'UTR SNP C T uc011mlq.1 Hybrid_Cap... view
ASPH p.K336* 8 62496559 62496559 SUDHL4_HAEMATOP... 37 Nonsense_Mutation SNP T A uc003xuj.2 ASPH_uc011leg.1... Hybrid_Cap... view
ATP13A5 p.W925_splice 3 193018999 193018999 SUDHL4_HAEMATOP... 37 Splice_Site_SNP SNP C A uc011bsq.1 Hybrid_Cap... view
BCL2 18 60795780 60795780 SUDHL4_HAEMATOP... 37 3'UTR SNP T A uc002lit.1 BCL2_uc002liu.1... Hybrid_Cap... view
BCL2 p.S117R 18 60985549 60985549 SUDHL4_HAEMATOP... 37 Missense_Mutation SNP G C uc002lit.1 BCL2_uc002liu.1... Hybrid_Cap... view
BCL3 19 45262965 45262968 SUDHL4_HAEMATOP... 37 3'UTR Del CCCC - uc010xxe.1 Hybrid_Cap...
CABC1 1 227171585 227171585 SUDHL4_HAEMATOP... 37 Intron Del T - uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CDC42BPB p.D946N 14 103426033 103426033 SUDHL4_HAEMATOP... 37 Missense_Mutation SNP C T uc001ymi.1 CDC42BPB_uc001y... Hybrid_Cap... view
CDK10 16 89758299 89758299 SUDHL4_HAEMATOP... 37 Intron SNP C T uc010cio.2 CDK10_uc002foa.... Hybrid_Cap... view
CDK20 p.P297fs 9 90582524 90582527 SUDHL4_HAEMATOP... 37 Frame_Shift_Del Del AGAT - uc004apr.2 CDK20_uc004aps.... Hybrid_Cap...
CHD1 p.P1684del 5 98192165 98192167 SUDHL4_HAEMATOP... 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CHD9 p.2164_2165SS>S 16 53338410 53338412 SUDHL4_HAEMATOP... 37 In_Frame_Del Del TTC - uc002ehb.2 CHD9_uc002egy.2... Hybrid_Cap...
CIITA p.P293S 16 10997689 10997689 SUDHL4_HAEMATOP... 37 Missense_Mutation SNP C T uc002daj.3 CIITA_uc002dai.... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 SUDHL4_HAEMATOP... 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN6 3 1339681 1339686 SUDHL4_HAEMATOP... 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
EHBP1 p.R863Q 2 63206345 63206345 SUDHL4_HAEMATOP... 37 Missense_Mutation SNP G A uc002sby.2 EHBP1_uc010fcp.... Hybrid_Cap... view
EP300 22 41574970 41574972 SUDHL4_HAEMATOP... 37 3'UTR Del GTA - rs76489032 uc003azl.3 Hybrid_Cap...
EPHB6 7 142568771 142568771 SUDHL4_HAEMATOP... 37 3'UTR Del C - uc011kst.1 EPHB6_uc011ksu.... Hybrid_Cap...
ETV1 7 14028708 14028708 SUDHL4_HAEMATOP... 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FGFR1OP 6 167453519 167453520 SUDHL4_HAEMATOP... 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 SUDHL4_HAEMATOP... 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLI1 11 128638217 128638217 SUDHL4_HAEMATOP... 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLT4 5 180035183 180035185 SUDHL4_HAEMATOP... 37 Intron Del AGT - uc003mlz.3 FLT4_uc003mma.3... Hybrid_Cap...
GLYATL2 11 58601858 58601858 SUDHL4_HAEMATOP... 37 3'UTR Del T - uc001nnd.3 GLYATL2_uc009ym... Hybrid_Cap...
GRIA3 X 122318386 122318387 SUDHL4_HAEMATOP... 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
HERC2 15 28356801 28356801 SUDHL4_HAEMATOP... 37 3'UTR SNP G A uc001zbj.2 HERC2_uc001zbi.... Hybrid_Cap... view
HNF1A 12 121434630 121434631 SUDHL4_HAEMATOP... 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
ILK 11 6630029 6630029 SUDHL4_HAEMATOP... 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
KLK7 19 51480672 51480675 SUDHL4_HAEMATOP... 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LRP1B p.T2649I 2 141283493 141283493 SUDHL4_HAEMATOP... 37 Missense_Mutation SNP G A uc002tvj.1 Hybrid_Cap... view
LRP1B p.C962R 2 141739732 141739732 SUDHL4_HAEMATOP... 37 Missense_Mutation SNP A G uc002tvj.1 LRP1B_uc010fnl.... Hybrid_Cap... view
MAML2 p.604_607QQQQ>Q 11 95825375 95825383 SUDHL4_HAEMATOP... 37 In_Frame_Del Del TGCTG... - rs113349418 uc001pfw.1 Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 SUDHL4_HAEMATOP... 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP2K6 17 67516353 67516353 SUDHL4_HAEMATOP... 37 Intron SNP A T rs77138194 uc002jij.2 MAP2K6_uc002jii... Hybrid_Cap... view
MAP3K1 p.T949del 5 56177849 56177851 SUDHL4_HAEMATOP... 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 SUDHL4_HAEMATOP... 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAPK12 22 50695245 50695245 SUDHL4_HAEMATOP... 37 Intron SNP G A uc003bkm.1 MAPK12_uc003bkn... Hybrid_Cap... view
MAPKAPK3 3 50685575 50685575 SUDHL4_HAEMATOP... 37 3'UTR Del A - rs76026164 uc003day.1 MAPKAPK3_uc003d... Hybrid_Cap...
MAST2 p.D1093H 1 46497939 46497939 SUDHL4_HAEMATOP... 37 Missense_Mutation SNP G C uc001cov.2 MAST2_uc001cow.... Hybrid_Cap... view
MSH3 p.PPA66del 5 79950742 79950750 SUDHL4_HAEMATOP... 37 In_Frame_Del Del CCCCC... - rs60484572;rs1047489 uc003kgz.2 DHFR_uc011ctl.1... Hybrid_Cap...
NCAM1 11 112832307 112832308 SUDHL4_HAEMATOP... 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 SUDHL4_HAEMATOP... 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA2 8 71129001 71129001 SUDHL4_HAEMATOP... 37 Splice_Site_SNP SNP T A uc003xyn.1 Hybrid_Cap... view
NCOA3 p.QQQ1272del 20 46279815 46279823 SUDHL4_HAEMATOP... 37 In_Frame_Del Del GCAGC... - uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 SUDHL4_HAEMATOP... 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 SUDHL4_HAEMATOP... 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NR3C1 5 142780419 142780419 SUDHL4_HAEMATOP... 37 Splice_Site_SNP SNP T A uc003lmy.2 NR3C1_uc003lmz.... Hybrid_Cap... view
NRBP2 p.F488L 8 144917874 144917874 SUDHL4_HAEMATOP... 37 Missense_Mutation SNP G C uc011lkt.1 NRBP2_uc003yzv.... Hybrid_Cap... view
PAPPA p.R189H 9 118949583 118949583 SUDHL4_HAEMATOP... 37 Missense_Mutation SNP G A uc004bjn.2 PAPPA_uc011lxp.... Hybrid_Cap... view
PCDH15 p.S1957N 10 55581637 55581637 SUDHL4_HAEMATOP... 37 Missense_Mutation SNP C T uc010qhy.1 PCDH15_uc010qhq... Hybrid_Cap... view
PDE4DIP p.V486fs 1 144917828 144917828 SUDHL4_HAEMATOP... 37 Frame_Shift_Del Del A - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PI4KA p.R517_splice 22 21156259 21156259 SUDHL4_HAEMATOP... 37 Splice_Site_SNP SNP A G uc002zsz.3 PI4KA_uc010gsq.... Hybrid_Cap... view
PIK3C2G p.P129del 12 18435399 18435401 SUDHL4_HAEMATOP... 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PIK3CB p.I767F 3 138403483 138403483 SUDHL4_HAEMATOP... 37 Missense_Mutation SNP T A uc011bmq.1 PIK3CB_uc011bmn... Hybrid_Cap... view
PIM1 6 37138308 37138308 SUDHL4_HAEMATOP... 37 5'UTR SNP G A uc003onk.2 PIM1_uc011dtw.1... Hybrid_Cap... view
PKHD1 p.D3230fs 6 51612725 51612725 SUDHL4_HAEMATOP... 37 Frame_Shift_Del Del T - uc003pah.1 PKHD1_uc010jzn.... Hybrid_Cap...
PLK2 p.I329M 5 57753029 57753029 SUDHL4_HAEMATOP... 37 Missense_Mutation SNP A C uc003jrn.2 Hybrid_Cap... view
PPARGC1A 4 23797328 23797328 SUDHL4_HAEMATOP... 37 3'UTR SNP A G uc003gqs.2 PPARGC1A_uc003g... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 SUDHL4_HAEMATOP... 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PTPRC p.C226Y 1 198673625 198673625 SUDHL4_HAEMATOP... 37 Missense_Mutation SNP G A uc001gur.1 PTPRC_uc001gus.... Hybrid_Cap... view
PTPRC p.R660Q 1 198701439 198701439 SUDHL4_HAEMATOP... 37 Missense_Mutation SNP G A uc001gur.1 PTPRC_uc001gus.... Hybrid_Cap... view
PTPRC p.Q1050* 1 198719701 198719702 SUDHL4_HAEMATOP... 37 Nonsense_Mutation DNP CC TT uc001gur.1 PTPRC_uc001gus.... Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 SUDHL4_HAEMATOP... 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
ROBO2 p.N705K 3 77623781 77623781 SUDHL4_HAEMATOP... 37 Missense_Mutation SNP C A uc003dpz.2 ROBO2_uc003dpy.... Hybrid_Cap... view
ROBO2 3 77666937 77666937 SUDHL4_HAEMATOP... 37 Intron Del A - rs78745603 uc003dpz.2 ROBO2_uc003dpy.... Hybrid_Cap...
SMG1 p.Y1858D 16 18860590 18860590 SUDHL4_HAEMATOP... 37 Missense_Mutation SNP A C uc002dfm.2 SMG1_uc010bwb.2... Hybrid_Cap... view
SORL1 p.R1490C 11 121466430 121466430 SUDHL4_HAEMATOP... 37 Missense_Mutation SNP C T uc001pxx.2 SORL1_uc010rzp.... Hybrid_Cap... view
STK31 7 23872024 23872025 SUDHL4_HAEMATOP... 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TAF1L 9 32629916 32629916 SUDHL4_HAEMATOP... 37 3'UTR SNP A G uc003zrg.1 Hybrid_Cap... view
TBK1 p.I334L 12 64878090 64878090 SUDHL4_HAEMATOP... 37 Missense_Mutation SNP A C uc001ssc.1 Hybrid_Cap... view
TG p.P1923S 8 133980119 133980119 SUDHL4_HAEMATOP... 37 Missense_Mutation SNP C T uc003ytw.2 TG_uc010mdw.2_M... Hybrid_Cap... view
TLK2 p.T78A 17 60600503 60600503 SUDHL4_HAEMATOP... 37 Missense_Mutation SNP A G uc010ddp.2 TLK2_uc002izx.3... Hybrid_Cap... view
TP53 p.R273C 17 7577121 7577121 SUDHL4_HAEMATOP... 37 Missense_Mutation SNP G A uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TP63 3 189507518 189507519 SUDHL4_HAEMATOP... 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TRRAP p.I2813V 7 98575906 98575906 SUDHL4_HAEMATOP... 37 Missense_Mutation SNP A G uc003upp.2 TRRAP_uc011kis.... Hybrid_Cap... view
VCPIP1 p.K390E 8 67578026 67578026 SUDHL4_HAEMATOP... 37 Missense_Mutation SNP T C uc003xwn.2 SGK3_uc003xwp.2... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 SUDHL4_HAEMATOP... 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...