Annotation Summary for Cell Line: SUP-B15  

Cell line primary name: SUP-B15
Cell line aliases:
Gender: M
Site Primary: haematopoietic_and_lymphoid_tissue
Histology: lymphoid_neoplasm
Hist Subtype1: acute_lymphoblastic_B_cell_leukaemia
Notes:
Source: ATCC
Expression arrays: AGENT_p_NCLE_RNA6_HG-U133_Plus_2_G04_436500
SNP arrays: LOBBY_p_NCLE_DNAAffy6_GenomeWideSNP_6_G07_437372
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in SUP-B15

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 SUPB15_HAEMATOP... 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ABL2 1 179086419 179086420 SUPB15_HAEMATOP... 37 Intron Ins - A rs72207641 uc001gmj.3 ABL2_uc010pnf.1... Hybrid_Cap...
ACACA 17 35766564 35766564 SUPB15_HAEMATOP... 37 5'UTR Del A - uc002hno.2 ACACA_uc002hnn.... Hybrid_Cap...
ADAM17 2 9630245 9630245 SUPB15_HAEMATOP... 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 SUPB15_HAEMATOP... 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADAMTS18 16 77326941 77326941 SUPB15_HAEMATOP... 37 Intron SNP C G uc002ffc.3 ADAMTS18_uc010c... Hybrid_Cap... view
AKAP12 p.1531_1532insE 6 151674116 151674117 SUPB15_HAEMATOP... 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP9 p.1335_1336insQ 7 91652178 91652179 SUPB15_HAEMATOP... 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
APC p.R24R 5 112090659 112090659 SUPB15_HAEMATOP... 37 Silent SNP A G uc010jby.2 APC_uc011cvt.1_... Hybrid_Cap... view
ASPH p.A264_splice 8 62550924 62550925 SUPB15_HAEMATOP... 37 Splice_Site_Ins Ins - A rs5891816 uc003xuj.2 ASPH_uc011leg.1... Hybrid_Cap...
BCL3 19 45262965 45262965 SUPB15_HAEMATOP... 37 3'UTR Del C - uc010xxe.1 Hybrid_Cap...
BMP4 14 54416601 54416602 SUPB15_HAEMATOP... 37 3'UTR Ins - ATT rs74495140;rs76335800 uc001xal.3 BMP4_uc010aoh.2... Hybrid_Cap...
CABC1 1 227171585 227171585 SUPB15_HAEMATOP... 37 Intron Del T - uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CDK11B 1 1654066 1654068 SUPB15_HAEMATOP... 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CHD9 p.SS2191del 16 53338483 53338488 SUPB15_HAEMATOP... 37 In_Frame_Del Del TCTTC... - uc002ehb.2 CHD9_uc002egy.2... Hybrid_Cap...
CLK1 2 201717887 201717887 SUPB15_HAEMATOP... 37 3'UTR SNP T A uc010zhi.1 CLK1_uc002uwd.2... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 SUPB15_HAEMATOP... 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
DACH1 13 72014625 72014626 SUPB15_HAEMATOP... 37 3'UTR Ins - T rs117109529 uc010thn.1 DACH1_uc010tho.... Hybrid_Cap...
DGKB 7 14216345 14216346 SUPB15_HAEMATOP... 37 Intron Ins - AGACT uc003ssz.2 DGKB_uc011jxt.1... Hybrid_Cap...
DOCK3 p.V1962I 3 51418781 51418781 SUPB15_HAEMATOP... 37 Missense_Mutation SNP G A uc011bds.1 Hybrid_Cap... view
DYRK4 p.T152I 12 4700456 4700456 SUPB15_HAEMATOP... 37 Missense_Mutation SNP C T uc009zeh.1 DYRK4_uc001qmx.... Hybrid_Cap... view
DYRK4 p.Q547H 12 4721859 4721859 SUPB15_HAEMATOP... 37 Missense_Mutation SNP A C uc009zeh.1 DYRK4_uc001qmx.... Hybrid_Cap... view
EP300 22 41574970 41574972 SUPB15_HAEMATOP... 37 3'UTR Del GTA - rs76489032 uc003azl.3 Hybrid_Cap...
EPHA6 3 97367230 97367231 SUPB15_HAEMATOP... 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
EXT1 8 118811807 118811807 SUPB15_HAEMATOP... 37 3'UTR Del T - uc003yok.1 Hybrid_Cap...
EXT2 p.P276R 11 44135836 44135836 SUPB15_HAEMATOP... 37 Missense_Mutation SNP C G uc001mya.2 EXT2_uc010rfo.1... Hybrid_Cap... view
FANCC 9 97863893 97863893 SUPB15_HAEMATOP... 37 3'UTR SNP T C rs55687573 uc004avh.2 Hybrid_Cap... view
FBN2 5 127595046 127595048 SUPB15_HAEMATOP... 37 3'UTR Del TTA - uc003kuu.2 Hybrid_Cap...
FGFR1OP 6 167453519 167453520 SUPB15_HAEMATOP... 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 SUPB15_HAEMATOP... 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLI1 11 128564011 128564012 SUPB15_HAEMATOP... 37 5'UTR Ins - GCAGGGCGCTC uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLT4 5 180035183 180035185 SUPB15_HAEMATOP... 37 Intron Del AGT - uc003mlz.3 FLT4_uc003mma.3... Hybrid_Cap...
FN1 2 216244182 216244185 SUPB15_HAEMATOP... 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GPR112 p.D2657del X 135474445 135474447 SUPB15_HAEMATOP... 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 SUPB15_HAEMATOP... 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
ILK 11 6630029 6630029 SUPB15_HAEMATOP... 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
INPP4B p.Q464L 4 143081683 143081683 SUPB15_HAEMATOP... 37 Missense_Mutation SNP T A uc003iix.3 INPP4B_uc003iiw... Hybrid_Cap... view
ITGAV p.S924N 2 187540395 187540395 SUPB15_HAEMATOP... 37 Missense_Mutation SNP G A rs56316527 uc002upq.2 ITGAV_uc010frs.... Hybrid_Cap... view
ITGB1 10 33197131 33197134 SUPB15_HAEMATOP... 37 Intron Del CTTT - rs116966876 uc001iwq.3 ITGB1_uc001iwp.... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 SUPB15_HAEMATOP... 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KIAA1549 p.V553M 7 138602715 138602715 SUPB15_HAEMATOP... 37 Missense_Mutation SNP C T uc011kql.1 KIAA1549_uc003v... Hybrid_Cap... view
KLK7 19 51480672 51480675 SUPB15_HAEMATOP... 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LRP1B p.S4375G 2 141032012 141032012 SUPB15_HAEMATOP... 37 Missense_Mutation SNP T C uc002tvj.1 Hybrid_Cap... view
LRP2 p.G4493V 2 169995127 169995127 SUPB15_HAEMATOP... 37 Missense_Mutation SNP C A uc002ues.2 Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 SUPB15_HAEMATOP... 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 SUPB15_HAEMATOP... 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 SUPB15_HAEMATOP... 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAP3K5 p.P1080L 6 136904865 136904865 SUPB15_HAEMATOP... 37 Missense_Mutation SNP G A uc003qhc.2 MAP3K5_uc011edj... Hybrid_Cap... view
MAPKAPK3 3 50685575 50685575 SUPB15_HAEMATOP... 37 3'UTR Del A - rs76026164 uc003day.1 MAPKAPK3_uc003d... Hybrid_Cap...
MCM3APAS 21 47671275 47671276 SUPB15_HAEMATOP... 37 3'UTR Ins - AAT rs67797185 uc002zin.2 MCM3APAS_uc002z... Hybrid_Cap...
MSH3 p.PPA66del 5 79950742 79950750 SUPB15_HAEMATOP... 37 In_Frame_Del Del CCCCC... - rs60484572;rs1047489 uc003kgz.2 DHFR_uc011ctl.1... Hybrid_Cap...
NCAM1 11 112832307 112832308 SUPB15_HAEMATOP... 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 SUPB15_HAEMATOP... 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA3 p.Q1276del 20 46279837 46279839 SUPB15_HAEMATOP... 37 In_Frame_Del Del CAG - rs2664555 uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NLRP1 p.V1398D 17 5418303 5418303 SUPB15_HAEMATOP... 37 Missense_Mutation SNP A T uc002gci.2 NLRP1_uc002gcg.... Hybrid_Cap... view
NPM1 5 170837734 170837734 SUPB15_HAEMATOP... 37 3'UTR Del T - uc011dex.1 NPM1_uc003mbi.2... Hybrid_Cap...
NPR1 1 153665919 153665920 SUPB15_HAEMATOP... 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 SUPB15_HAEMATOP... 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NR1H3 p.A175G 11 47282951 47282951 SUPB15_HAEMATOP... 37 Missense_Mutation SNP C G uc001nel.2 NR1H3_uc009yll.... Hybrid_Cap... view
PAX3 2 223158653 223158653 SUPB15_HAEMATOP... 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PKHD1 p.V881A 6 51909837 51909837 SUPB15_HAEMATOP... 37 Missense_Mutation SNP A G uc003pah.1 PKHD1_uc003pai.... Hybrid_Cap... view
PRKCZ p.D452N 1 2105404 2105404 SUPB15_HAEMATOP... 37 Missense_Mutation SNP G A uc001aiq.2 PRKCZ_uc001air.... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 SUPB15_HAEMATOP... 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 SUPB15_HAEMATOP... 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
ROCK2 p.D1203_splice 2 11334379 11334385 SUPB15_HAEMATOP... 37 Splice_Site_Del Del TACTC... - rs55839233 uc002rbd.1 Hybrid_Cap...
RPN1 p.L11V 3 128369613 128369613 SUPB15_HAEMATOP... 37 Missense_Mutation SNP G C uc003ekr.1 RPN1_uc011bkq.1... Hybrid_Cap... view
RXRA 9 137313735 137313737 SUPB15_HAEMATOP... 37 Intron TNP GCA TAC uc004cfb.2 RXRA_uc004cfc.1... Hybrid_Cap...
STK31 7 23872024 23872025 SUPB15_HAEMATOP... 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TAF1 p.G68D X 70587371 70587371 SUPB15_HAEMATOP... 37 Missense_Mutation SNP G A uc004dzt.3 BCYRN1_uc011mpt... Hybrid_Cap... view
TCF21 6 134210497 134210498 SUPB15_HAEMATOP... 37 5'UTR Ins - TCTC rs35199378 uc003qei.3 TCF21_uc003qej.... Hybrid_Cap...
TEC 4 48139307 48139310 SUPB15_HAEMATOP... 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TMEM123 11 102269398 102269398 SUPB15_HAEMATOP... 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TTBK1 p.E771del 6 43250726 43250728 SUPB15_HAEMATOP... 37 In_Frame_Del Del GAA - uc003ouq.1 Hybrid_Cap...
TTN 2 179391639 179391640 SUPB15_HAEMATOP... 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
VEGFC p.S419_splice 4 177605082 177605084 SUPB15_HAEMATOP... 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
XPO4 p.S498_splice 13 21382722 21382722 SUPB15_HAEMATOP... 37 Splice_Site_SNP SNP T A uc001unq.3 Hybrid_Cap... view