Annotation Summary for Cell Line: SW620  

Cell line primary name: SW620
Cell line aliases:
Gender: M
Site Primary: large_intestine
Histology: carcinoma
Hist Subtype1: adenocarcinoma
Notes: Metastatic pair: SW620 and SW480 were derived from the same patient
Source: ATCC
Expression arrays: METIS_p_NCLE_RNA1_Human_U133_Plus_2.0_G04_241000
SNP arrays: LIMPS_p_NCLE_DNA2N_GenomeWideSNP_6_C04_246664
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in SW620

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ADAM17 2 9630245 9630245 SW620_LARGE_INT... 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM22 p.H872Y 7 87810869 87810869 SW620_LARGE_INT... 37 Missense_Mutation SNP C T uc003ujp.1 ADAM22_uc003ujk... Hybrid_Cap... view
ADAM28 8 24211994 24211997 SW620_LARGE_INT... 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADAM32 p.I662T 8 39112015 39112015 SW620_LARGE_INT... 37 Missense_Mutation SNP T C uc003xmt.3 ADAM32_uc011lch... Hybrid_Cap... view
ADAMTS19 p.Y319N 5 128862036 128862036 SW620_LARGE_INT... 37 Missense_Mutation SNP T A uc003kvb.1 ADAMTS19_uc003k... Hybrid_Cap... view
ADAMTS2 p.F773fs 5 178557071 178557071 SW620_LARGE_INT... 37 Frame_Shift_Del Del G - uc003mjw.2 Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 SW620_LARGE_INT... 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
APC p.Q1338* 5 112175303 112175303 SW620_LARGE_INT... 37 Nonsense_Mutation SNP C T uc010jby.2 APC_uc011cvt.1_... Hybrid_Cap... view
AURKC 19 57742494 57742507 SW620_LARGE_INT... 37 5'UTR Del GGACG... - rs67926438;rs112039303;rs59094959 uc002qoe.2 AURKC_uc002qoc.... Hybrid_Cap...
BCL9 p.P514fs 1 147091501 147091501 SW620_LARGE_INT... 37 Frame_Shift_Del Del C - uc001epq.2 BCL9_uc010ozr.1... Hybrid_Cap...
BMP4 14 54416601 54416602 SW620_LARGE_INT... 37 3'UTR Ins - AT rs74495140;rs76335800 uc001xal.3 BMP4_uc010aoh.2... Hybrid_Cap...
BTG1 12 92537706 92537707 SW620_LARGE_INT... 37 3'UTR Ins - T rs33983967 uc001tby.3 BTG1_uc001tbv.1... Hybrid_Cap...
BTRC p.H382Q 10 103294466 103294466 SW620_LARGE_INT... 37 Missense_Mutation SNP T G uc001kta.2 BTRC_uc001ktb.2... Hybrid_Cap... view
CAD p.E2194A 2 27466289 27466289 SW620_LARGE_INT... 37 Missense_Mutation SNP A C uc002rji.2 CAD_uc010eyw.2_... Hybrid_Cap... view
CARD10 p.KE272del 22 37906309 37906314 SW620_LARGE_INT... 37 In_Frame_Del Del CTCCT... - uc003asx.1 CARD10_uc003ast... Hybrid_Cap...
CCND2 p.V284M 12 4409155 4409155 SW620_LARGE_INT... 37 Missense_Mutation SNP G A uc001qmo.2 Hybrid_Cap... view
CDK11B 1 1654066 1654068 SW620_LARGE_INT... 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CHIC2 4 54876131 54876132 SW620_LARGE_INT... 37 3'UTR Del AC - rs68107873;rs4437313 uc003haj.1 PDGFRA_uc003haa... Hybrid_Cap...
CHUK p.W742* 10 101949368 101949368 SW620_LARGE_INT... 37 Nonsense_Mutation SNP C T uc001kqp.2 Hybrid_Cap... view
CLTC p.P1671S 17 57771184 57771184 SW620_LARGE_INT... 37 Missense_Mutation SNP C T uc002ixr.1 CLTC_uc002ixq.1... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 SW620_LARGE_INT... 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN5 p.A687V 11 100126546 100126546 SW620_LARGE_INT... 37 Missense_Mutation SNP C T uc001pga.2 CNTN5_uc001pfz.... Hybrid_Cap... view
CREB3L2 p.T100del 7 137612914 137612916 SW620_LARGE_INT... 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CSNK1A1L 13 37678315 37678315 SW620_LARGE_INT... 37 3'UTR SNP A G uc001uwm.1 Hybrid_Cap... view
CSNK1G3 p.Y64F 5 122888813 122888813 SW620_LARGE_INT... 37 Missense_Mutation SNP A T uc003ktl.2 CSNK1G3_uc003kt... Hybrid_Cap... view
CXCL12 10 44873992 44873993 SW620_LARGE_INT... 37 Intron Ins - CT rs117617571 uc001jbh.2 CXCL12_uc001jbf... Hybrid_Cap...
DGKG p.Q359* 3 185986631 185986631 SW620_LARGE_INT... 37 Nonsense_Mutation SNP G A uc003fqa.2 DGKG_uc003fqb.2... Hybrid_Cap... view
DNMT1 p.L603M 19 10265287 10265287 SW620_LARGE_INT... 37 Missense_Mutation SNP G T uc010xlc.1 DNMT1_uc002mng.... Hybrid_Cap... view
DPYD p.A818S 1 97658795 97658795 SW620_LARGE_INT... 37 Missense_Mutation SNP C A uc001drv.2 Hybrid_Cap... view
DYRK1A 21 38884966 38884967 SW620_LARGE_INT... 37 3'UTR Ins - T rs72430212 uc002ywk.2 DYRK1A_uc002ywi... Hybrid_Cap...
EIF3A p.E862K 10 120809387 120809387 SW620_LARGE_INT... 37 Missense_Mutation SNP C T uc001ldu.2 EIF3A_uc010qsu.... Hybrid_Cap... view
EP300 p.P1440L 22 41566442 41566442 SW620_LARGE_INT... 37 Missense_Mutation SNP C T uc003azl.3 Hybrid_Cap... view
EP300 22 41574970 41574972 SW620_LARGE_INT... 37 3'UTR Del GTA - rs76489032 uc003azl.3 Hybrid_Cap...
EPHA6 3 97367230 97367231 SW620_LARGE_INT... 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
EPHB1 p.V322V 3 134851560 134851560 SW620_LARGE_INT... 37 Silent SNP C T uc003eqt.2 EPHB1_uc010htz.... Hybrid_Cap... view
EPS15 1 51887719 51887719 SW620_LARGE_INT... 37 Intron Del A - uc001csq.1 EPS15_uc009vyz.... Hybrid_Cap...
ESR2 p.S39R 14 64749589 64749589 SW620_LARGE_INT... 37 Missense_Mutation SNP T G uc001xha.1 ESR2_uc001xgu.2... Hybrid_Cap... view
FASN p.A1102T 17 80045049 80045049 SW620_LARGE_INT... 37 Missense_Mutation SNP C T uc002kdu.2 FASN_uc002kdw.1... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 SW620_LARGE_INT... 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FIGF p.H335Y X 15364317 15364317 SW620_LARGE_INT... 37 Missense_Mutation SNP G A uc004cwt.1 Hybrid_Cap... view
FLI1 11 128638217 128638217 SW620_LARGE_INT... 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
GHR p.Q148K 5 42699928 42699928 SW620_LARGE_INT... 37 Missense_Mutation SNP C A uc003jmt.2 GHR_uc011cpq.1_... Hybrid_Cap... view
GRIA3 X 122318386 122318387 SW620_LARGE_INT... 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GRIK1 p.E218Q 21 31045377 31045377 SW620_LARGE_INT... 37 Missense_Mutation SNP C G uc011acs.1 GRIK1_uc002ynn.... Hybrid_Cap... view
GUCY2C 12 14827464 14827466 SW620_LARGE_INT... 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HDAC2 6 114262093 114262093 SW620_LARGE_INT... 37 3'UTR SNP G T uc003pwd.1 HDAC2_uc003pwc.... Hybrid_Cap... view
HERC2 p.A3358T 15 28414787 28414787 SW620_LARGE_INT... 37 Missense_Mutation SNP C T uc001zbj.2 Hybrid_Cap... view
HIF1A 14 62213929 62213930 SW620_LARGE_INT... 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
IL1R1 p.V432I 2 102792096 102792096 SW620_LARGE_INT... 37 Missense_Mutation SNP G A uc002tbq.2 IL1R1_uc010fix.... Hybrid_Cap... view
ILK 11 6630029 6630029 SW620_LARGE_INT... 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ISG15 p.A40T 1 949478 949478 SW620_LARGE_INT... 37 Missense_Mutation SNP G A uc001acj.3 Hybrid_Cap... view
ITPR2 p.R470_splice 12 26834804 26834805 SW620_LARGE_INT... 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KIAA2022 p.E725Q X 73962219 73962219 SW620_LARGE_INT... 37 Missense_Mutation SNP C G uc004eby.2 Hybrid_Cap... view
KRAS p.G12V 12 25398284 25398284 SW620_LARGE_INT... 37 Missense_Mutation SNP C A uc001rgp.1 KRAS_uc001rgq.1... Hybrid_Cap... view
LRGUK p.R528C 7 133884008 133884008 SW620_LARGE_INT... 37 Missense_Mutation SNP C T uc003vrm.1 Hybrid_Cap... view
LRP1B p.R4062* 2 141092061 141092061 SW620_LARGE_INT... 37 Nonsense_Mutation SNP T A uc002tvj.1 Hybrid_Cap... view
MAF 16 79628537 79628537 SW620_LARGE_INT... 37 Intron Del T - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 SW620_LARGE_INT... 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP2K7 p.L312_splice 19 7976216 7976216 SW620_LARGE_INT... 37 Splice_Site_SNP SNP G A uc002miv.2 MAP2K7_uc010xka... Hybrid_Cap... view
MAP3K1 p.T949del 5 56177849 56177851 SW620_LARGE_INT... 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K1 5 56189586 56189586 SW620_LARGE_INT... 37 3'UTR SNP T G uc003jqw.3 Hybrid_Cap... view
MAP3K14 p.R218_splice 17 43364293 43364294 SW620_LARGE_INT... 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAP4K2 11 64569656 64569656 SW620_LARGE_INT... 37 Intron SNP C T uc001obh.2 MAP4K2_uc001obi... Hybrid_Cap... view
MAPK12 p.K155K 22 50695067 50695067 SW620_LARGE_INT... 37 Silent SNP C T uc003bkm.1 MAPK12_uc003bkn... Hybrid_Cap... view
MAPKAPK3 3 50685575 50685575 SW620_LARGE_INT... 37 3'UTR Del A - rs76026164 uc003day.1 MAPKAPK3_uc003d... Hybrid_Cap...
MARK1 p.Q410H 1 220808825 220808825 SW620_LARGE_INT... 37 Missense_Mutation SNP G T uc009xdw.2 MARK1_uc001hmn.... Hybrid_Cap... view
MLL3 p.K832E 7 151945025 151945025 SW620_LARGE_INT... 37 Missense_Mutation SNP T C uc003wla.2 Hybrid_Cap... view
MLLT6 17 36881873 36881873 SW620_LARGE_INT... 37 3'UTR Del C - uc002hqi.3 MLLT6_uc002hqk.... Hybrid_Cap...
MSH3 p.PPA66del 5 79950742 79950750 SW620_LARGE_INT... 37 In_Frame_Del Del CCCCC... - rs60484572;rs1047489 uc003kgz.2 DHFR_uc011ctl.1... Hybrid_Cap...
MSH6 p.E221D 2 48025785 48025785 SW620_LARGE_INT... 37 Missense_Mutation SNP A C rs41557217 uc002rwd.3 MSH6_uc002rwc.2... Hybrid_Cap... view
MYST4 p.1104_1105insE 10 76781905 76781906 SW620_LARGE_INT... 37 In_Frame_Ins Ins - GAA rs111976843 uc001jwn.1 MYST4_uc001jwm.... Hybrid_Cap...
NCAM1 11 112832307 112832308 SW620_LARGE_INT... 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 SW620_LARGE_INT... 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 SW620_LARGE_INT... 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NFIA p.P146S 1 61554094 61554094 SW620_LARGE_INT... 37 Missense_Mutation SNP C T uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap... view
NONO p.D422Y X 70518649 70518649 SW620_LARGE_INT... 37 Missense_Mutation SNP G T uc004dzo.2 BCYRN1_uc011mpt... Hybrid_Cap... view
NPR1 1 153665919 153665920 SW620_LARGE_INT... 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 SW620_LARGE_INT... 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
OBSCN p.E5974K 1 228529201 228529201 SW620_LARGE_INT... 37 Missense_Mutation SNP G A uc009xez.1 OBSCN_uc001hsn.... Hybrid_Cap... view
PAX3 2 223158653 223158653 SW620_LARGE_INT... 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PGGT1B 5 114548071 114548072 SW620_LARGE_INT... 37 3'UTR Ins - C uc003kqw.3 PGGT1B_uc003kqx... Hybrid_Cap...
PIK3C2G 12 18800990 18800990 SW620_LARGE_INT... 37 3'UTR Del A - rs16914368 uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PML 15 74326962 74326962 SW620_LARGE_INT... 37 Intron SNP G A uc002awv.2 PML_uc002awm.2_... Hybrid_Cap... view
PRKDC p.A1302G 8 48802984 48802984 SW620_LARGE_INT... 37 Missense_Mutation SNP G C uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 SW620_LARGE_INT... 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PRKG2 p.G392S 4 82065465 82065465 SW620_LARGE_INT... 37 Missense_Mutation SNP C T uc003hmh.2 PRKG2_uc011ccf.... Hybrid_Cap... view
PRKX p.I252T X 3544520 3544520 SW620_LARGE_INT... 37 Missense_Mutation SNP A G uc010nde.2 Hybrid_Cap... view
RAG1 p.R34Q 11 36594955 36594955 SW620_LARGE_INT... 37 Missense_Mutation SNP G A uc001mwu.3 RAG1_uc001mwt.2... Hybrid_Cap... view
RAPGEF2 4 160189200 160189201 SW620_LARGE_INT... 37 5'UTR Ins - T rs72011511 uc003iqg.3 Hybrid_Cap...
RASGRF1 p.R220Q 15 79339307 79339307 SW620_LARGE_INT... 37 Missense_Mutation SNP C T uc002beq.2 RASGRF1_uc002be... Hybrid_Cap... view
RHPN2 p.Q30fs 19 33535248 33535251 SW620_LARGE_INT... 37 Frame_Shift_Del Del GTTT - uc002nuf.2 RHPN2_uc010xro.... Hybrid_Cap...
RIOK1 p.R534S 6 7417569 7417569 SW620_LARGE_INT... 37 Missense_Mutation SNP A C uc003mxn.2 RIOK1_uc003mxo.... Hybrid_Cap... view
RIPK2 p.P228A 8 90784009 90784009 SW620_LARGE_INT... 37 Missense_Mutation SNP C G uc003yee.2 RIPK2_uc003yef.... Hybrid_Cap... view
RPS6KA5 14 91360733 91360734 SW620_LARGE_INT... 37 Intron Ins - T rs77438853 uc001xys.2 RPS6KA5_uc010tw... Hybrid_Cap...
SIRT1 p.V383I 10 69667859 69667859 SW620_LARGE_INT... 37 Missense_Mutation SNP G A uc001jnd.2 SIRT1_uc010qis.... Hybrid_Cap... view
SPP1 p.A248S 4 88903806 88903806 SW620_LARGE_INT... 37 Missense_Mutation SNP G T uc011cde.1 SPP1_uc003hra.2... Hybrid_Cap... view
STARD3 p.D218N 17 37815309 37815309 SW620_LARGE_INT... 37 Missense_Mutation SNP G A uc002hsd.2 STARD3_uc010weh... Hybrid_Cap... view
STK31 7 23872024 23872025 SW620_LARGE_INT... 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
STK36 p.G13V 2 219537590 219537590 SW620_LARGE_INT... 37 Missense_Mutation SNP G T uc002viu.2 STK36_uc002viv.... Hybrid_Cap... view
STRADB 2 202319467 202319468 SW620_LARGE_INT... 37 Splice_Site_DNP DNP AG TT uc002uyd.3 Hybrid_Cap...
TG p.S1235S 8 133919003 133919003 SW620_LARGE_INT... 37 Silent SNP G A uc003ytw.2 TG_uc010mdw.2_5... Hybrid_Cap... view
TRIM33 1 114940215 114940216 SW620_LARGE_INT... 37 3'UTR Ins - G rs68133208 uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TRIO p.A1611T 5 14406071 14406071 SW620_LARGE_INT... 37 Missense_Mutation SNP G A uc003jff.2 TRIO_uc003jfg.2... Hybrid_Cap... view
TRPM7 15 50853851 50853851 SW620_LARGE_INT... 37 3'UTR SNP A T uc001zyt.3 TRPM7_uc001zyr.... Hybrid_Cap... view
TRPS1 8 116635872 116635873 SW620_LARGE_INT... 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TSC1 9 135771333 135771333 SW620_LARGE_INT... 37 3'UTR Del A - rs115091888 uc004cca.2 TSC1_uc004ccb.3... Hybrid_Cap...
TTN p.T14025N 2 179477670 179477670 SW620_LARGE_INT... 37 Missense_Mutation SNP G T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.C5376Y 2 179592446 179592446 SW620_LARGE_INT... 37 Missense_Mutation SNP C T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
UNC13C p.L546R 15 54306737 54306737 SW620_LARGE_INT... 37 Missense_Mutation SNP T G uc002ack.2 Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 SW620_LARGE_INT... 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
VRK2 2 58386880 58386880 SW620_LARGE_INT... 37 3'UTR SNP C T uc002rzo.2 VRK2_uc010fcb.2... Hybrid_Cap... view
WNK3 p.S905N X 54276067 54276067 SW620_LARGE_INT... 37 Missense_Mutation SNP C T uc004dtc.1 WNK3_uc004dtd.1... Hybrid_Cap... view