Annotation Summary for Cell Line: Saos-2  

Cell line primary name: Saos-2
Cell line aliases:
Gender: F
Site Primary: bone
Histology: osteosarcoma
Hist Subtype1: NS
Notes:
Source: ATCC
Expression arrays: CASED_p_NCLE_RNA4_HG-U133_Plus_2_E08_383690
SNP arrays:
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in Saos-2

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ADAM17 17 35766564 35766564 SAOS2_BONE 37 5'UTR Del A - uc002hno.2 ACACA_uc002hnn.... Hybrid_Cap...
ADAM18 2 9630245 9630245 SAOS2_BONE 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 SAOS2_BONE 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 SAOS2_BONE 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ALPK1 p.1335_1336insQ 7 91652178 91652179 SAOS2_BONE 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ALPK2 4 113347609 113347610 SAOS2_BONE 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
ALPK3 12 92537706 92537707 SAOS2_BONE 37 3'UTR Ins - T rs33983967 uc001tby.3 BTG1_uc001tbv.1... Hybrid_Cap...
ASPH p.A175P 15 34640592 34640592 SAOS2_BONE 37 Missense_Mutation SNP G C uc010ucc.1 C15orf55_uc010u... Hybrid_Cap... view
BCR 10 18828721 18828722 SAOS2_BONE 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
BCR p.V1201_splice 22 19189003 19189004 SAOS2_BONE 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
BRD2 p.K974fs 10 126678123 126678123 SAOS2_BONE 37 Frame_Shift_Del Del T - uc001lie.3 CTBP2_uc009yak.... Hybrid_Cap...
BTG1 13 72014625 72014626 SAOS2_BONE 37 3'UTR Ins - T rs117109529 uc010thn.1 DACH1_uc010tho.... Hybrid_Cap...
CASC5 p.T412S 11 113281547 113281547 SAOS2_BONE 37 Missense_Mutation SNP T A uc001pnz.2 DRD2_uc010rwv.1... Hybrid_Cap... view
CHD1 21 38884966 38884967 SAOS2_BONE 37 3'UTR Ins - T rs72430212 uc002ywk.2 DYRK1A_uc002ywi... Hybrid_Cap...
CHD8 6 12296150 12296151 SAOS2_BONE 37 Intron Ins - T rs66570617 uc003nae.3 EDN1_uc003nad.2... Hybrid_Cap...
CIITA 8 117768048 117768048 SAOS2_BONE 37 Intron SNP G C uc003yob.2 EIF3H_uc003yoa.... Hybrid_Cap... view
CLTCL1 7 14028708 14028708 SAOS2_BONE 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
CTBP2 p.V670F 3 10106100 10106100 SAOS2_BONE 37 Missense_Mutation SNP G T uc003buw.2 FANCD2_uc003bux... Hybrid_Cap... view
CUBN p.I935L 3 10116301 10116301 SAOS2_BONE 37 Missense_Mutation SNP A C rs61751578 uc003buw.2 FANCD2_uc003bux... Hybrid_Cap... view
CXCR4 p.G2505A 15 48714205 48714205 SAOS2_BONE 37 Missense_Mutation SNP C G uc001zwx.1 FBN1_uc010beo.1... Hybrid_Cap... view
CYP27B1 2 216244182 216244185 SAOS2_BONE 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
DACH1 p.V2520I X 135453648 135453648 SAOS2_BONE 37 Missense_Mutation SNP G A uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap... view
DDR2 p.D2657del X 135474445 135474447 SAOS2_BONE 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
DIP2C X 122318386 122318387 SAOS2_BONE 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
DLC1 12 14827464 14827466 SAOS2_BONE 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
DST 14 62213929 62213930 SAOS2_BONE 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
DYRK1A 12 121434630 121434631 SAOS2_BONE 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
EIF4G1 11 6630029 6630029 SAOS2_BONE 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
EP300 10 33197131 33197134 SAOS2_BONE 37 Intron Del CTTT - rs116966876 uc001iwq.3 ITGB1_uc001iwp.... Hybrid_Cap...
EPHA5 p.R470_splice 12 26834804 26834805 SAOS2_BONE 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
EPHA6 p.A415V 3 124044984 124044984 SAOS2_BONE 37 Missense_Mutation SNP C T uc003ehg.2 KALRN_uc010hrv.... Hybrid_Cap... view
EPHB1 p.G671E 4 55968651 55968651 SAOS2_BONE 37 Missense_Mutation SNP C T uc003has.2 KDR_uc003hat.1_... Hybrid_Cap... view
EPHB4 p.V166M 19 51483154 51483154 SAOS2_BONE 37 Missense_Mutation SNP C T uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap... view
ETV1 16 79628325 79628325 SAOS2_BONE 37 3'UTR Del A - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
FANCF p.A548D 11 95825552 95825552 SAOS2_BONE 37 Missense_Mutation SNP G T uc001pfw.1 Hybrid_Cap... view
FASLG p.Q767_splice 4 140651585 140651587 SAOS2_BONE 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
FGFR1OP p.R218_splice 17 43364293 43364294 SAOS2_BONE 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
FN1 p.N372K 2 39535087 39535087 SAOS2_BONE 37 Missense_Mutation SNP A T uc002rro.2 MAP4K3_uc002rrp... Hybrid_Cap... view
GHR 3 50685575 50685575 SAOS2_BONE 37 3'UTR Del A - rs76026164 uc003day.1 MAPKAPK3_uc003d... Hybrid_Cap...
GPR112 p.L1411R 1 46500573 46500573 SAOS2_BONE 37 Missense_Mutation SNP T G uc001cov.2 MAST2_uc001cow.... Hybrid_Cap... view
GUCY2C p.L1622H 1 46501206 46501206 SAOS2_BONE 37 Missense_Mutation SNP T A uc001cov.2 MAST2_uc001cow.... Hybrid_Cap... view
IDH1 17 36881873 36881873 SAOS2_BONE 37 3'UTR Del C - uc002hqi.3 MLLT6_uc002hqk.... Hybrid_Cap...
KSR2 p.C717F 6 31729310 31729310 SAOS2_BONE 37 Missense_Mutation SNP G T uc003nwt.1 MSH5_uc003nwu.1... Hybrid_Cap... view
MAF p.T716A 2 48027268 48027268 SAOS2_BONE 37 Missense_Mutation SNP A G uc002rwd.3 MSH6_uc002rwc.2... Hybrid_Cap... view
MAML3 17 55709256 55709256 SAOS2_BONE 37 Intron SNP C A uc002iuz.1 MSI2_uc010wnm.1... Hybrid_Cap... view
MAP2K3 p.R666* 16 46746678 46746678 SAOS2_BONE 37 Nonsense_Mutation SNP G A uc002eei.3 MYLK3_uc010vge.... Hybrid_Cap... view
MAP3K1 p.G439G 22 26165200 26165200 SAOS2_BONE 37 Silent SNP A G uc003abz.1 MYO18B_uc003aca... Hybrid_Cap... view
MAP3K14 11 112832307 112832308 SAOS2_BONE 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
MAP3K4 11 112832340 112832340 SAOS2_BONE 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
MSH3 p.Q1276del 20 46279864 46279866 SAOS2_BONE 37 In_Frame_Del Del CAA - rs1132443;rs28529067 uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
MYST4 10 51589331 51589335 SAOS2_BONE 37 3'UTR Del TTAGC - uc009xon.2 PARG_uc001jih.2... Hybrid_Cap...
NCAM1 p.K313_splice 13 52718050 52718051 SAOS2_BONE 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NCAM1 p.E12G 14 24687621 24687621 SAOS2_BONE 37 Missense_Mutation SNP T C uc001wnn.2 CHMP4A_uc001wnj... Hybrid_Cap... view
NEK3 1 61921185 61921186 SAOS2_BONE 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NF1 p.R765K 5 36985576 36985576 SAOS2_BONE 37 Missense_Mutation SNP G A rs116491215 uc003jkl.3 NIPBL_uc003jkk.... Hybrid_Cap... view
NPAT 1 153665919 153665920 SAOS2_BONE 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NPM1 p.176_177insQ 19 50881822 50881823 SAOS2_BONE 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NR1H2 2 223158653 223158653 SAOS2_BONE 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
NR1H2 p.S1187W 11 71724989 71724989 SAOS2_BONE 37 Missense_Mutation SNP G C uc001orl.1 NUMA1_uc009ysw.... Hybrid_Cap... view
NSD1 p.V486fs 1 144917828 144917828 SAOS2_BONE 37 Frame_Shift_Del Del A - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
OR4E2 7 95221928 95221928 SAOS2_BONE 37 Intron Del A - uc003uoa.2 PDK4_uc003unz.2... Hybrid_Cap...
PCM1 5 114548071 114548072 SAOS2_BONE 37 3'UTR Ins - C uc003kqw.3 PGGT1B_uc003kqx... Hybrid_Cap...
PIK3R1 11 100933598 100933599 SAOS2_BONE 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PKHD1 p.P129del 12 18435399 18435401 SAOS2_BONE 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PLCB2 16 81954996 81954997 SAOS2_BONE 37 Intron Ins - T uc002fgt.2 PLCG2_uc010chg.... Hybrid_Cap...
RPS6KC1 p.S809N 8 69009309 69009309 SAOS2_BONE 37 Missense_Mutation SNP G A uc003xxv.1 PREX2_uc003xxu.... Hybrid_Cap... view
RPS6KL1 p.N401T 16 67961472 67961472 SAOS2_BONE 37 Missense_Mutation SNP A C uc002euv.2 Hybrid_Cap... view
STK25 p.M605_splice 13 49027249 49027249 SAOS2_BONE 37 Splice_Site_SNP SNP T C uc001vcb.2 Hybrid_Cap... view
STK31 p.R766fs 8 145738768 145738768 SAOS2_BONE 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
TEC p.R928W 11 116729081 116729081 SAOS2_BONE 37 Missense_Mutation SNP G A uc001ppy.2 SIK3_uc001ppz.2... Hybrid_Cap... view
TIAM1 p.V1208G 1 16256358 16256358 SAOS2_BONE 37 Missense_Mutation SNP T G uc001axk.1 SPEN_uc010obp.1... Hybrid_Cap... view
TMEM123 7 23872024 23872025 SAOS2_BONE 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TNKS2 6 134210497 134210498 SAOS2_BONE 37 5'UTR Ins - TCTC rs35199378 uc003qei.3 TCF21_uc003qej.... Hybrid_Cap...
TP53 4 48139307 48139310 SAOS2_BONE 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TRIM33 9 84303263 84303263 SAOS2_BONE 37 5'UTR SNP G A uc004alz.2 TLE1_uc004aly.2... Hybrid_Cap... view
TRPS1 8 116635872 116635873 SAOS2_BONE 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TTBK1 2 171850178 171850179 SAOS2_BONE 37 3'UTR Ins - AA rs71008739 uc002ugo.2 TLK1_uc002ugn.2... Hybrid_Cap...
TTN 11 102269398 102269398 SAOS2_BONE 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TTN 11 102269461 102269461 SAOS2_BONE 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TTN 3 189507518 189507519 SAOS2_BONE 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TYRO3 p.H157P 11 18051059 18051059 SAOS2_BONE 37 Missense_Mutation SNP T G uc001mnp.2 TPH1_uc009yhe.2... Hybrid_Cap... view
UBE2O p.N581S 17 74394959 74394959 SAOS2_BONE 37 Missense_Mutation SNP T C uc002jrm.3 UBE2O_uc002jrn.... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 SAOS2_BONE 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
VEGFC 5 114462096 114462096 SAOS2_BONE 37 3'UTR SNP G A uc003kqs.2 TRIM36_uc011cwc... Hybrid_Cap... view
WHSC1 p.R501H 4 1932444 1932444 SAOS2_BONE 37 Missense_Mutation SNP G A uc003gdz.3 WHSC1_uc003geb.... Hybrid_Cap... view
WHSC1 4 1944104 1944104 SAOS2_BONE 37 Intron SNP C A uc003gdz.3 WHSC1_uc003geb.... Hybrid_Cap... view
ZNF423 p.C755* 16 49670798 49670798 SAOS2_BONE 37 Nonsense_Mutation SNP G T uc002efs.2 ZNF423_uc010vgn... Hybrid_Cap... view