Annotation Summary for Cell Line: T84  

Cell line primary name: T84
Cell line aliases:
Gender: M
Site Primary: large_intestine
Histology: carcinoma
Hist Subtype1: adenocarcinoma
Notes:
Source: ATCC
Expression arrays: PARES_p_NCLE_RNA_Redo_HG-U133_Plus_2_D06_257680
SNP arrays: LIMPS_p_NCLE_DNA2N_GenomeWideSNP_6_E12_246728
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in T84

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ABI1 p.V153F 10 27065999 27065999 T84_LARGE_INTES... 37 Missense_Mutation SNP C A uc001isx.2 ABI1_uc001ite.2... Hybrid_Cap... view
ADAM17 2 9630245 9630245 T84_LARGE_INTES... 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 T84_LARGE_INTES... 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AFF3 p.D393A 2 100289040 100289040 T84_LARGE_INTES... 37 Missense_Mutation SNP T G uc002taf.2 AFF3_uc002tag.2... Hybrid_Cap... view
AKAP12 p.1531_1532insE 6 151674116 151674117 T84_LARGE_INTES... 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP9 7 91570396 91570396 T84_LARGE_INTES... 37 5'UTR SNP G T uc003ulg.2 AKAP9_uc003uld.... Hybrid_Cap... view
ALPK2 p.EDTST1006del 18 56204388 56204402 T84_LARGE_INTES... 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ALS2 p.P192L 2 202626142 202626142 T84_LARGE_INTES... 37 Missense_Mutation SNP G A uc002uyo.2 ALS2_uc002uyp.3... Hybrid_Cap... view
ANAPC5 12 121746114 121746114 T84_LARGE_INTES... 37 3'UTR SNP G A uc001uag.2 ANAPC5_uc010szu... Hybrid_Cap... view
APC p.L1488fs 5 112175755 112175755 T84_LARGE_INTES... 37 Frame_Shift_Del Del A - uc010jby.2 APC_uc011cvt.1_... Hybrid_Cap...
AR X 66788777 66788777 T84_LARGE_INTES... 37 Intron SNP C A uc004dwu.1 AR_uc011mpd.1_I... Hybrid_Cap... view
ARID1A 1 27107263 27107264 T84_LARGE_INTES... 37 3'UTR Ins - C rs3841356 uc001bmv.1 ARID1A_uc001bmu... Hybrid_Cap...
ATR p.D2037G 3 142204093 142204093 T84_LARGE_INTES... 37 Missense_Mutation SNP T C uc003eux.3 Hybrid_Cap... view
BCL3 19 45262965 45262968 T84_LARGE_INTES... 37 3'UTR Del CCCC - uc010xxe.1 Hybrid_Cap...
BCR 22 23631813 23631814 T84_LARGE_INTES... 37 Intron Ins - C rs66503844 uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BIRC6 p.I3837V 2 32743899 32743899 T84_LARGE_INTES... 37 Missense_Mutation SNP A G uc010ezu.2 Hybrid_Cap... view
BLNK p.R49P 10 98002508 98002508 T84_LARGE_INTES... 37 Missense_Mutation SNP C G uc001kls.3 BLNK_uc001kme.3... Hybrid_Cap... view
BMPR1A p.L307W 10 88678980 88678980 T84_LARGE_INTES... 37 Missense_Mutation SNP T G uc001kdy.2 Hybrid_Cap... view
CACNB2 10 18828721 18828722 T84_LARGE_INTES... 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CCNT1 p.I244F 12 49089589 49089589 T84_LARGE_INTES... 37 Missense_Mutation SNP T A uc001rse.1 CCNT1_uc009zkz.... Hybrid_Cap... view
CD40 20 44751636 44751636 T84_LARGE_INTES... 37 Intron SNP C A uc002xrg.1 CD40_uc002xrf.1... Hybrid_Cap... view
CDC42BPA p.A1456V 1 227213814 227213814 T84_LARGE_INTES... 37 Missense_Mutation SNP G A rs55687355 uc001hqr.2 CDC42BPA_uc001h... Hybrid_Cap... view
CDK11B 1 1654066 1654068 T84_LARGE_INTES... 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CEP110 p.S1822* 9 123927262 123927262 T84_LARGE_INTES... 37 Nonsense_Mutation SNP C G uc004bkx.1 CEP110_uc004blb... Hybrid_Cap... view
CHIC2 4 54876132 54876132 T84_LARGE_INTES... 37 3'UTR Del C - rs4437313 uc003haj.1 PDGFRA_uc003haa... Hybrid_Cap...
CIC p.Y249* 19 42791861 42791861 T84_LARGE_INTES... 37 Nonsense_Mutation SNP C A uc002otf.1 Hybrid_Cap... view
CIITA p.G32S 16 10989180 10989180 T84_LARGE_INTES... 37 Missense_Mutation SNP G A uc002daj.3 CIITA_uc002dai.... Hybrid_Cap... view
CIITA p.Q1118R 16 11017117 11017117 T84_LARGE_INTES... 37 Missense_Mutation SNP A G uc002daj.3 CIITA_uc002dai.... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 T84_LARGE_INTES... 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CSPG4 p.G191C 15 75982835 75982835 T84_LARGE_INTES... 37 Missense_Mutation SNP C A uc002baw.2 Hybrid_Cap... view
CXCL12 10 44873992 44873993 T84_LARGE_INTES... 37 Intron Ins - CT rs117617571 uc001jbh.2 CXCL12_uc001jbf... Hybrid_Cap...
DACH1 13 72014625 72014626 T84_LARGE_INTES... 37 3'UTR Ins - T rs117109529 uc010thn.1 DACH1_uc010tho.... Hybrid_Cap...
DACH1 p.T571S 13 72063139 72063139 T84_LARGE_INTES... 37 Missense_Mutation SNP G C uc010thn.1 DACH1_uc010tho.... Hybrid_Cap... view
DFNA5 7 24783982 24783982 T84_LARGE_INTES... 37 Intron Del C - uc010kus.1 DFNA5_uc003swz.... Hybrid_Cap...
DIP2C p.R1121L 10 390840 390840 T84_LARGE_INTES... 37 Missense_Mutation SNP C A uc001ifp.2 DIP2C_uc009xhi.... Hybrid_Cap... view
DPYD p.E666D 1 97839177 97839177 T84_LARGE_INTES... 37 Missense_Mutation SNP C G uc001drv.2 Hybrid_Cap... view
EP300 22 41574970 41574972 T84_LARGE_INTES... 37 3'UTR Del GTA - rs76489032 uc003azl.3 Hybrid_Cap...
EPHA6 3 97367230 97367231 T84_LARGE_INTES... 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
EPHA6 3 97467610 97467611 T84_LARGE_INTES... 37 3'UTR Ins - CT uc010how.1 Hybrid_Cap...
FANCB p.G63R X 14883446 14883446 T84_LARGE_INTES... 37 Missense_Mutation SNP C T uc004cwg.1 FANCB_uc004cwh.... Hybrid_Cap... view
FANCD2 3 10143086 10143087 T84_LARGE_INTES... 37 3'UTR Ins - A uc003bux.1 FANCD2_uc003buy... Hybrid_Cap...
FGFR1OP 6 167453519 167453520 T84_LARGE_INTES... 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FLNA X 153599616 153599616 T84_LARGE_INTES... 37 5'UTR SNP T G uc004fkk.2 FLNA_uc010nuu.1... Hybrid_Cap... view
FN1 p.R2150W 2 216236898 216236898 T84_LARGE_INTES... 37 Missense_Mutation SNP G A uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap... view
GPR112 p.D2657del X 135474445 135474447 T84_LARGE_INTES... 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 T84_LARGE_INTES... 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 T84_LARGE_INTES... 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HIF1A 14 62213929 62213930 T84_LARGE_INTES... 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HNF1A 12 121434630 121434631 T84_LARGE_INTES... 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
ILK 11 6630029 6630029 T84_LARGE_INTES... 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITGB1 10 33197112 33197112 T84_LARGE_INTES... 37 Intron SNP A G uc001iwq.3 ITGB1_uc001iwp.... Hybrid_Cap... view
ITIH5L p.T1148S X 54777724 54777724 T84_LARGE_INTES... 37 Missense_Mutation SNP T A uc004dtj.2 Hybrid_Cap... view
KIAA1409 p.Q1793H 14 94103572 94103572 T84_LARGE_INTES... 37 Missense_Mutation SNP G T uc001ybv.1 KIAA1409_uc001y... Hybrid_Cap... view
KLK7 19 51480672 51480675 T84_LARGE_INTES... 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
KRAS p.G13D 12 25398281 25398281 T84_LARGE_INTES... 37 Missense_Mutation SNP C T rs112445441 uc001rgp.1 KRAS_uc001rgq.1... Hybrid_Cap... view
LDHA p.I164M 11 18422544 18422544 T84_LARGE_INTES... 37 Missense_Mutation SNP T G uc010rdd.1 LDHA_uc001mok.3... Hybrid_Cap... view
MAF 16 79628537 79628537 T84_LARGE_INTES... 37 Intron Del T - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 T84_LARGE_INTES... 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 T84_LARGE_INTES... 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 T84_LARGE_INTES... 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MCM3AP p.S1939L 21 47655309 47655309 T84_LARGE_INTES... 37 Missense_Mutation SNP G A rs10229 uc002zir.1 MCM3APAS_uc002z... Hybrid_Cap... view
MLLT4 p.R1487C 6 168352517 168352517 T84_LARGE_INTES... 37 Missense_Mutation SNP C T uc003qwd.2 MLLT4_uc003qwb.... Hybrid_Cap... view
MYLK p.E1430_splice 3 123368043 123368044 T84_LARGE_INTES... 37 Splice_Site_Ins Ins - G rs41431347 uc003ego.2 MYLK_uc010hrr.2... Hybrid_Cap...
NCAM1 11 112832307 112832308 T84_LARGE_INTES... 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 T84_LARGE_INTES... 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAPD3 p.C1039F 11 134038935 134038935 T84_LARGE_INTES... 37 Missense_Mutation SNP C A uc001qhd.1 NCAPD3_uc010scm... Hybrid_Cap... view
NFATC1 18 77287653 77287654 T84_LARGE_INTES... 37 3'UTR Del AA - uc010xfg.1 NFATC1_uc002lnd... Hybrid_Cap...
NFIA 1 61921185 61921186 T84_LARGE_INTES... 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 T84_LARGE_INTES... 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NRK p.R1387W X 105189963 105189963 T84_LARGE_INTES... 37 Missense_Mutation SNP C T uc004emd.2 NRK_uc011msi.1_... Hybrid_Cap... view
PAX3 2 223158653 223158653 T84_LARGE_INTES... 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAX5 9 37034095 37034095 T84_LARGE_INTES... 37 5'UTR Del C - uc003zzo.1 PAX5_uc011lpw.1... Hybrid_Cap...
PAX5 9 37034103 37034103 T84_LARGE_INTES... 37 5'UTR SNP T C rs112221838 uc003zzo.1 PAX5_uc011lpw.1... Hybrid_Cap... view
PDE4DIP p.V486fs 1 144917828 144917828 T84_LARGE_INTES... 37 Frame_Shift_Del Del A - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDK4 7 95221928 95221928 T84_LARGE_INTES... 37 Intron Del A - uc003uoa.2 PDK4_uc003unz.2... Hybrid_Cap...
PGR 11 100933598 100933599 T84_LARGE_INTES... 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PIK3C2B p.S677F 1 204423833 204423833 T84_LARGE_INTES... 37 Missense_Mutation SNP G A uc001haw.2 PIK3C2B_uc010pq... Hybrid_Cap... view
PIK3C2G p.P129del 12 18435399 18435401 T84_LARGE_INTES... 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PIK3CA p.E542K 3 178936082 178936082 T84_LARGE_INTES... 37 Missense_Mutation SNP G A uc003fjk.2 Hybrid_Cap... view
PIKFYVE p.T283T 2 209153480 209153480 T84_LARGE_INTES... 37 Silent SNP T G uc002vcz.2 PIKFYVE_uc010fu... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 T84_LARGE_INTES... 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PRPF4B p.S381P 6 4032892 4032892 T84_LARGE_INTES... 37 Missense_Mutation SNP T C uc003mvv.2 PRPF4B_uc011dhv... Hybrid_Cap... view
PTPN22 p.R510H 1 114380493 114380493 T84_LARGE_INTES... 37 Missense_Mutation SNP C T uc001eds.2 PTPN22_uc009wgq... Hybrid_Cap... view
RECQL4 p.R766fs 8 145738768 145738768 T84_LARGE_INTES... 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RET p.R189H 10 43598018 43598018 T84_LARGE_INTES... 37 Missense_Mutation SNP G A uc001jal.2 RET_uc001jak.1_... Hybrid_Cap... view
RET p.S561I 10 43608334 43608334 T84_LARGE_INTES... 37 Missense_Mutation SNP G T uc001jal.2 RET_uc001jak.1_... Hybrid_Cap... view
RPN1 3 128339072 128339072 T84_LARGE_INTES... 37 3'UTR Del G - uc003ekr.1 RPN1_uc011bkq.1... Hybrid_Cap...
RPS6KA4 p.A516G 11 64137036 64137036 T84_LARGE_INTES... 37 Missense_Mutation SNP C G uc001oae.2 RPS6KA4_uc001oa... Hybrid_Cap... view
SIRT1 p.D379N 10 69667847 69667847 T84_LARGE_INTES... 37 Missense_Mutation SNP G A uc001jnd.2 SIRT1_uc010qis.... Hybrid_Cap... view
SMAD4 p.K340N 18 48591857 48591857 T84_LARGE_INTES... 37 Missense_Mutation SNP G C uc010xdp.1 SMAD4_uc002lfb.... Hybrid_Cap... view
SMG1 p.H3376D 16 18827800 18827800 T84_LARGE_INTES... 37 Missense_Mutation SNP G C uc002dfm.2 SMG1_uc010bwb.2... Hybrid_Cap... view
SNX19 p.E331del 11 130784841 130784843 T84_LARGE_INTES... 37 In_Frame_Del Del CTT - uc001qgk.3 SNX19_uc010sce.... Hybrid_Cap...
STAT1 2 191840353 191840353 T84_LARGE_INTES... 37 Intron Del T - uc002usj.2 STAT1_uc010fse.... Hybrid_Cap...
SULF2 20 46286967 46286967 T84_LARGE_INTES... 37 3'UTR SNP T C uc002xto.2 SULF2_uc002xtr.... Hybrid_Cap... view
TLK1 2 171850178 171850179 T84_LARGE_INTES... 37 3'UTR Ins - AA rs71008739 uc002ugo.2 TLK1_uc002ugn.2... Hybrid_Cap...
TMEM123 11 102269398 102269398 T84_LARGE_INTES... 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TNFRSF12A p.E120Q 16 3071795 3071795 T84_LARGE_INTES... 37 Missense_Mutation SNP G C uc002csv.3 TNFRSF12A_uc002... Hybrid_Cap... view
TP53 p.G187_splice 17 7578290 7578290 T84_LARGE_INTES... 37 Splice_Site_SNP SNP C A uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TP63 3 189507518 189507519 T84_LARGE_INTES... 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TPO p.W233* 2 1459933 1459933 T84_LARGE_INTES... 37 Nonsense_Mutation SNP G A uc002qww.2 TPO_uc010ewj.2_... Hybrid_Cap... view
TTN p.Q19245L 2 179448471 179448471 T84_LARGE_INTES... 37 Missense_Mutation SNP T A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 T84_LARGE_INTES... 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...