Annotation Summary for Cell Line: TYK-nu  

Cell line primary name: TYK-nu
Cell line aliases:
Gender: F
Site Primary: ovary
Histology: carcinoma
Hist Subtype1: undifferentiated_carcinoma
Notes:
Source: HSRRB
Expression arrays: NIECE_p_NCLE_RNA3_HG-U133_Plus_2_A02_295992
SNP arrays: LIMPS_p_NCLE_DNA2N_GenomeWideSNP_6_E10_246724
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in TYK-nu

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ABL2 1 179076839 179076839 TYKNU_OVARY 37 3'UTR SNP C T uc001gmj.3 ABL2_uc010pnf.1... Hybrid_Cap... view
ADAM18 p.R726_splice 8 39581427 39581427 TYKNU_OVARY 37 Splice_Site_SNP SNP G C uc003xni.2 ADAM18_uc010lww... Hybrid_Cap... view
ADAM28 8 24211994 24211997 TYKNU_OVARY 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 TYKNU_OVARY 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ALK p.M1478T 2 29416520 29416520 TYKNU_OVARY 37 Missense_Mutation SNP A G uc002rmy.2 ALK_uc010ymo.1_... Hybrid_Cap... view
ALPK1 4 113347609 113347610 TYKNU_OVARY 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 TYKNU_OVARY 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ALS2 2 202587706 202587707 TYKNU_OVARY 37 Intron Ins - A rs3219165 uc002uyo.2 ALS2_uc002uyp.3... Hybrid_Cap...
ASPH p.A264_splice 8 62550924 62550925 TYKNU_OVARY 37 Splice_Site_Ins Ins - A rs5891816 uc003xuj.2 ASPH_uc011leg.1... Hybrid_Cap...
ASPH p.D194N 8 62559348 62559348 TYKNU_OVARY 37 Missense_Mutation SNP C T uc003xuj.2 ASPH_uc011leg.1... Hybrid_Cap... view
ASTN1 p.G283W 1 177001610 177001610 TYKNU_OVARY 37 Missense_Mutation SNP C A uc001glc.2 ASTN1_uc001glb.... Hybrid_Cap... view
ATRX p.I2390V X 76776298 76776298 TYKNU_OVARY 37 Missense_Mutation SNP T C uc004ecp.3 ATRX_uc004ecq.3... Hybrid_Cap... view
AURKC 19 57742494 57742507 TYKNU_OVARY 37 5'UTR Del GGACG... - rs67926438;rs112039303;rs59094959 uc002qoe.2 AURKC_uc002qoc.... Hybrid_Cap...
BCL11A p.M550V 2 60688399 60688399 TYKNU_OVARY 37 Missense_Mutation SNP T C uc002sae.1 BCL11A_uc002sab... Hybrid_Cap... view
BMP4 14 54416601 54416602 TYKNU_OVARY 37 3'UTR Ins - AT rs74495140;rs76335800 uc001xal.3 BMP4_uc010aoh.2... Hybrid_Cap...
BRD3 p.S715F 9 136898749 136898749 TYKNU_OVARY 37 Missense_Mutation SNP G A uc004cew.2 Hybrid_Cap... view
BRF2 8 37701957 37701957 TYKNU_OVARY 37 3'UTR SNP G A uc003xkk.2 Hybrid_Cap... view
CACNB2 10 18828721 18828722 TYKNU_OVARY 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CDC42BPG p.R695G 11 64602413 64602413 TYKNU_OVARY 37 Missense_Mutation SNP T C uc001obs.3 Hybrid_Cap... view
CDK12 p.P697S 17 37646967 37646967 TYKNU_OVARY 37 Missense_Mutation SNP C T uc010cvv.2 CDK12_uc010wef.... Hybrid_Cap... view
CDX2 13 28537245 28537245 TYKNU_OVARY 37 3'UTR SNP C T uc001urv.2 Hybrid_Cap... view
CHIC2 4 54876132 54876132 TYKNU_OVARY 37 3'UTR Del C - rs4437313 uc003haj.1 PDGFRA_uc003haa... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 TYKNU_OVARY 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN6 3 1339681 1339686 TYKNU_OVARY 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
CREB3L2 p.T100del 7 137612914 137612916 TYKNU_OVARY 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CSPP1 p.E823fs 8 68070818 68070821 TYKNU_OVARY 37 Frame_Shift_Del Del AGAA - uc003xxi.2 CSPP1_uc003xxg.... Hybrid_Cap...
CUBN p.R828C 10 17113568 17113568 TYKNU_OVARY 37 Missense_Mutation SNP G A uc001ioo.2 Hybrid_Cap... view
DCLK3 3 36780342 36780342 TYKNU_OVARY 37 5'UTR SNP G A uc003cgi.2 Hybrid_Cap... view
DDR1 p.A196S 6 30859177 30859177 TYKNU_OVARY 37 Missense_Mutation SNP G T uc003nrv.2 DDR1_uc010jse.2... Hybrid_Cap... view
DGKB 7 14216345 14216346 TYKNU_OVARY 37 Intron Ins - AGACT uc003ssz.2 DGKB_uc011jxt.1... Hybrid_Cap...
DLL1 p.R146H 6 170597560 170597560 TYKNU_OVARY 37 Missense_Mutation SNP C T uc003qxm.2 DLL1_uc011ehc.1... Hybrid_Cap... view
DYRK1A 21 38884966 38884967 TYKNU_OVARY 37 3'UTR Ins - T rs72430212 uc002ywk.2 DYRK1A_uc002ywi... Hybrid_Cap...
DYRK3 p.S349G 1 206821588 206821588 TYKNU_OVARY 37 Missense_Mutation SNP A G uc001hej.2 DYRK3_uc001hek.... Hybrid_Cap... view
EDN1 6 12290729 12290729 TYKNU_OVARY 37 5'UTR Del A - uc003nae.3 EDN1_uc010jpb.2... Hybrid_Cap...
EPHA3 p.P384A 3 89391084 89391084 TYKNU_OVARY 37 Missense_Mutation SNP C G uc003dqy.2 EPHA3_uc003dqx.... Hybrid_Cap... view
EPHA6 3 97367230 97367231 TYKNU_OVARY 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
EPHA7 p.M893R 6 93956558 93956558 TYKNU_OVARY 37 Missense_Mutation SNP A C uc003poe.2 EPHA7_uc003pof.... Hybrid_Cap... view
ERCC4 p.R670Q 16 14038684 14038684 TYKNU_OVARY 37 Missense_Mutation SNP G A rs56129764 uc002dce.2 ERCC4_uc010uyz.... Hybrid_Cap... view
ETV1 7 14028708 14028708 TYKNU_OVARY 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FANCE 6 35434338 35434338 TYKNU_OVARY 37 3'UTR Del C - rs79295372 uc003oko.1 FANCE_uc010jvw.... Hybrid_Cap...
FGFR1OP 6 167453519 167453520 TYKNU_OVARY 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 TYKNU_OVARY 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLI1 11 128638217 128638217 TYKNU_OVARY 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLNC p.G2536R 7 128497216 128497216 TYKNU_OVARY 37 Missense_Mutation SNP G A uc003vnz.3 FLNC_uc003voa.3... Hybrid_Cap... view
FN1 2 216244182 216244185 TYKNU_OVARY 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
FOXP1 3 71008341 71008342 TYKNU_OVARY 37 3'UTR Ins - T rs11433724;rs114233617 uc003dol.2 FOXP1_uc003dom.... Hybrid_Cap...
GPR112 p.D2657del X 135474445 135474447 TYKNU_OVARY 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 TYKNU_OVARY 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 TYKNU_OVARY 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HNF1A 12 121434630 121434631 TYKNU_OVARY 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
HSP90B1 p.E791del 12 104341188 104341190 TYKNU_OVARY 37 In_Frame_Del Del GAA - rs117491163 uc001tkb.1 HSP90B1_uc010sw... Hybrid_Cap...
ILK 11 6630029 6630029 TYKNU_OVARY 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 TYKNU_OVARY 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KLK7 19 51480672 51480675 TYKNU_OVARY 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LRP2 p.R3192Q 2 170042283 170042283 TYKNU_OVARY 37 Missense_Mutation SNP C T uc002ues.2 Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 TYKNU_OVARY 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP2K1 15 66679649 66679650 TYKNU_OVARY 37 5'UTR Ins - C rs67229745 uc010bhq.2 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 TYKNU_OVARY 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAP3K7 6 91246267 91246268 TYKNU_OVARY 37 Intron Ins - A rs114677180 uc003pnz.1 MAP3K7_uc003pny... Hybrid_Cap...
MLL3 p.L4575F 7 151845289 151845289 TYKNU_OVARY 37 Missense_Mutation SNP G A uc003wla.2 MLL3_uc003wkz.2... Hybrid_Cap... view
MLL3 p.R2481_splice 7 151875096 151875097 TYKNU_OVARY 37 Splice_Site_Ins Ins - T uc003wla.2 MLL3_uc003wkz.2... Hybrid_Cap...
MMP9 p.P497S 20 44642052 44642052 TYKNU_OVARY 37 Missense_Mutation SNP C T uc002xqz.2 Hybrid_Cap... view
MSH2 p.Q419K 2 47657059 47657059 TYKNU_OVARY 37 Missense_Mutation SNP C A uc002rvz.2 MSH2_uc010yoh.1... Hybrid_Cap... view
MSH6 p.T1355fs 2 48033981 48033982 TYKNU_OVARY 37 Frame_Shift_Ins Ins - TTGA uc002rwd.3 MSH6_uc010fbj.2... Hybrid_Cap...
MYLK p.E1066del 3 123419117 123419119 TYKNU_OVARY 37 In_Frame_Del Del TTC - rs72491150 uc003ego.2 MYLK_uc011bjw.1... Hybrid_Cap...
MYST4 p.E1104del 10 76781906 76781908 TYKNU_OVARY 37 In_Frame_Del Del GAA - rs79644703 uc001jwn.1 MYST4_uc001jwm.... Hybrid_Cap...
NAV3 p.T1815M 12 78573389 78573389 TYKNU_OVARY 37 Missense_Mutation SNP C T uc001syp.2 NAV3_uc001syo.2... Hybrid_Cap... view
NCAM1 11 112832307 112832308 TYKNU_OVARY 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 TYKNU_OVARY 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 113092076 113092076 TYKNU_OVARY 37 Intron SNP T G uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap... view
NEK3 p.K313_splice 13 52718050 52718051 TYKNU_OVARY 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NFKB1 p.D917_splice 4 103534740 103534741 TYKNU_OVARY 37 Splice_Site_Ins Ins - A rs35795162 uc011cep.1 NFKB1_uc011ceq.... Hybrid_Cap...
NPM1 p.A186V 5 170827189 170827189 TYKNU_OVARY 37 Missense_Mutation SNP C T uc011dex.1 NPM1_uc003mbh.2... Hybrid_Cap... view
NPRL2 3 50384978 50384978 TYKNU_OVARY 37 3'UTR Del C - rs75013672 uc003daj.1 ZMYND10_uc003da... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 TYKNU_OVARY 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NRAS p.Q61K 1 115256530 115256530 TYKNU_OVARY 37 Missense_Mutation SNP G T uc009wgu.2 Hybrid_Cap... view
NRAS p.G12D 1 115258747 115258747 TYKNU_OVARY 37 Missense_Mutation SNP C T uc009wgu.2 Hybrid_Cap... view
NUP133 1 229577475 229577475 TYKNU_OVARY 37 3'UTR SNP T C uc001htn.2 Hybrid_Cap... view
NUP98 11 3697276 3697276 TYKNU_OVARY 37 3'UTR SNP G A uc001lyh.2 NUP98_uc001lyi.... Hybrid_Cap... view
OLFM4 p.D231H 13 53617360 53617360 TYKNU_OVARY 37 Missense_Mutation SNP G C uc001vhl.2 OLFM4_uc001vhk.... Hybrid_Cap... view
PAX3 2 223066017 223066018 TYKNU_OVARY 37 Intron Ins - C rs115619343 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAX3 2 223158653 223158653 TYKNU_OVARY 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PDE4DIP p.L601fs 1 144915624 144915624 TYKNU_OVARY 37 Frame_Shift_Del Del G - rs1778112 uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDE4DIP p.E243fs 1 144923729 144923729 TYKNU_OVARY 37 Frame_Shift_Del Del T - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDK4 7 95221928 95221928 TYKNU_OVARY 37 Intron Del A - uc003uoa.2 PDK4_uc003unz.2... Hybrid_Cap...
PGR 11 100933598 100933599 TYKNU_OVARY 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PHKG2 16 30762837 30762840 TYKNU_OVARY 37 Intron Del TCTG - uc002dzi.1 PHKG2_uc002dzj.... Hybrid_Cap...
PIK3C2B p.L819P 1 204416597 204416597 TYKNU_OVARY 37 Missense_Mutation SNP A G uc001haw.2 PIK3C2B_uc010pq... Hybrid_Cap... view
PIK3C2G p.P129del 12 18435399 18435401 TYKNU_OVARY 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PIKFYVE 2 209136235 209136235 TYKNU_OVARY 37 5'UTR SNP A G uc002vcz.2 PIKFYVE_uc010fu... Hybrid_Cap... view
PKHD1 p.W1725S 6 51889434 51889434 TYKNU_OVARY 37 Missense_Mutation SNP C G uc003pah.1 PKHD1_uc003pai.... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 TYKNU_OVARY 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
RGL2 6 33261359 33261359 TYKNU_OVARY 37 Intron SNP C T uc003odv.2 RGL2_uc003odu.2... Hybrid_Cap... view
RIMS2 p.P27S 8 104513193 104513193 TYKNU_OVARY 37 Missense_Mutation SNP C T uc003ylp.2 Hybrid_Cap... view
ROBO2 3 77666937 77666937 TYKNU_OVARY 37 Intron Del A - rs78745603 uc003dpz.2 ROBO2_uc003dpy.... Hybrid_Cap...
RPN1 3 128339057 128339057 TYKNU_OVARY 37 3'UTR Del A - rs3182459 uc003ekr.1 RPN1_uc011bkq.1... Hybrid_Cap...
RPS6KA5 14 91360733 91360734 TYKNU_OVARY 37 Intron Ins - T rs77438853 uc001xys.2 RPS6KA5_uc010tw... Hybrid_Cap...
RPS6KB1 17 58024224 58024225 TYKNU_OVARY 37 3'UTR Ins - AA rs67846207 uc002ixy.2 RPS6KB1_uc010dd... Hybrid_Cap...
RPS6KL1 14 75373626 75373627 TYKNU_OVARY 37 3'UTR Ins - TGAT uc001xqx.1 RPS6KL1_uc001xq... Hybrid_Cap...
SLC22A15 p.S319I 1 116577819 116577819 TYKNU_OVARY 37 Missense_Mutation SNP G T uc001egb.3 Hybrid_Cap... view
SLC22A3 p.T251A 6 160829847 160829847 TYKNU_OVARY 37 Missense_Mutation SNP A G uc003qti.2 SLC22A3_uc011ef... Hybrid_Cap... view
SMAD7 18 46447623 46447624 TYKNU_OVARY 37 3'UTR Ins - A uc002ldg.2 SMAD7_uc002ldf.... Hybrid_Cap...
SPTAN1 p.E1127K 9 131356617 131356617 TYKNU_OVARY 37 Missense_Mutation SNP G A uc004bvm.3 SPTAN1_uc011mbg... Hybrid_Cap... view
SRPK1 p.R126Q 6 35855814 35855814 TYKNU_OVARY 37 Missense_Mutation SNP C T uc003olj.2 SRPK1_uc011dtg.... Hybrid_Cap... view
STK25 2 242435659 242435662 TYKNU_OVARY 37 Intron Del AAGG - rs3215138;rs75497042 uc002wbm.2 STK25_uc002wbk.... Hybrid_Cap...
STK31 7 23872024 23872025 TYKNU_OVARY 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
STRADA 17 61781331 61781332 TYKNU_OVARY 37 Intron Ins - AGAACC rs66701913 uc002jbm.2 STRADA_uc002jbn... Hybrid_Cap...
TACC3 4 1739519 1739527 TYKNU_OVARY 37 Intron Del GCCAT... - rs114226356 uc003gdo.2 TACC3_uc010ibz.... Hybrid_Cap...
TAOK2 p.I853M 16 29998131 29998131 TYKNU_OVARY 37 Missense_Mutation SNP A G uc010bzm.1 BOLA2_uc010bzb.... Hybrid_Cap... view
TEC 4 48139307 48139310 TYKNU_OVARY 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TLK1 2 171850178 171850179 TYKNU_OVARY 37 3'UTR Ins - AA rs71008739 uc002ugo.2 TLK1_uc002ugn.2... Hybrid_Cap...
TMEM123 11 102269398 102269398 TYKNU_OVARY 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TP53 p.R175H 17 7578406 7578406 TYKNU_OVARY 37 Missense_Mutation SNP C T rs28934578 uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TRIM36 p.W576L 5 114466394 114466394 TYKNU_OVARY 37 Missense_Mutation SNP C A uc003kqs.2 TRIM36_uc011cwc... Hybrid_Cap... view
TRIM67 p.K522* 1 231339642 231339642 TYKNU_OVARY 37 Nonsense_Mutation SNP A T uc009xfn.1 Hybrid_Cap... view
TRPS1 8 116635872 116635873 TYKNU_OVARY 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TTN 2 179391639 179391640 TYKNU_OVARY 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
UBE3B 12 109972591 109972591 TYKNU_OVARY 37 3'UTR SNP C G uc001top.2 UBE3B_uc001toq.... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 TYKNU_OVARY 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...