News / Events
Jun 15, 2015: Currently there is a problem loading the tdf file into IGV. We are working on the problem and in the meantime please download the file from the BROWSE/DATA page as a workaround
Jun 8, 2015: The CCLE will be unavailable Sunday June 14th 12 noon through Monday June 15th, 12 noon for maintenance.
Mar 11, 2015: The CCLE portal will be unavailable on Tuesday 3/24/2015 for scheduled maintenance.
Feb 24, 2015: An updated version of the pharmacological profiling data is now available in Download section.
Jul 23, 2014: The browse cell lines, differential expression and gene set enrichment analyses are currently off-line. We are working to restore this functionality.
Jun 6, 2014: The differential expression, GSEA and GeneNeighbors analyses are currently not working due to the recent maintenance.
Jun 3, 2014: The CCLE will be unavailable from 10AM through 1PM EST Friday June 6th for maintenance.
Please register for full access to the data and analyses tools CCLE provides.
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Tutorials / Manuals
Tutorials, analysis descriptions and other documentation is available at:
HELP > DOCUMENTS
Frequently Altered Genes
clouds summarizing genes frequently altered in the datasets of this
portal are available in the
Mutation tag cloud
Pharmacogenomic agreement between two cancer cell line data sets., The Cancer Cell Line Encyclopedia Consortium & The Genomics of Drug Sensitivity in Cancer Consortium, Nature doi:10.1038/nature15736, 2015
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity, Barretina Caponigro Stransky et al., Nature doi:10.1038/nature11003, 2012
Project Achilles is a systematic effort aimed at identifying and cataloging genetic vulnerabilities across hundreds of genomically characterized cancer cell lines.
The Cancer Therapeutic Response Portal provides profiles of the impact of a small-molecule collection of 185 compounds on a panel of 242 cancer cell lines
The Genotype-Tissue Expression project (GTEx) aims to create a comprehensive public atlas of gene expression and regulation across multiple human tissues