OG1577
Number of Orthologs: 65Number of Taxa: 23
 
protein sequences nucleotide sequences
reconstructed gene tree sequence-based gene tree
tree-assisted protein alignment tree-assisted nucleotide alignment
naive protein alignment naive nucleotide alignment
sequence profile
promoter sequences
Orthogroup Homologies
Homologous Orthogroups (HMMSEARCH): 24525  7331  8615  ... 
Homologous Orthogroups (FASTA): 24525  7331  8615  ... 
Outgroup Homologs: ... 
Fungal Orthogroups Home
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MEMBERS
SpeciesGeneDomains
123456
S. cerevisiae YFL041W (FET5) YGOB
YMR058W (FET3) YGOB
YDR506C (YDR506C) YGOB
S. paradoxus spar345-g1.1
spar174-g8.1
spar349-g1.1
S. mikatae smik514-g10.1
smik581-g4.1
smik650-g27.1
S. bayanus sbayc629-g10.1
sbayc588-g18.1
sbayc631-g14.1
C. glabrata CAGL0K12738g YGOB
CAGL0F06413g YGOB
CAGL0J08481g YGOB
S. castellii Scas660.40 YGOB
K. waltii Kwal14.1085 YGOB
Kwal33.14936 YGOB
Kwal33.13230 YGOB
K. lactis KLLA0D05489g YGOB
KLLA0F26400g YGOB
KLLA0C01694g YGOB
S. kluyveri SAKL0B00836g
SAKL0B12056g
A. gossypii ABR228C YGOB
ADR132W YGOB
C. lusitaniae CLUG05225
CLUG01565
CLUG00109
D. hansenii DEHA2E12738g
DEHA2G05082g
DEHA2B06974g
C. guilliermondii PGUG03360.1
PGUG02941.1
PGUG00759.1
C. tropicalis CTRG05266.3
CTRG02996.3
CTRG02995.3
C. albicans orf19.943 (orf19.943)
orf19.4211 (FET3)
orf19.4212 (FET99)
orf19.4215 (FET34)
orf19.4213 (ORF19.4213)
C. parapsilosis CPAG02162
CPAG03729
CPAG03730
L. elongosporus LELG03709
LELG04638
LELG04639
Y. lipolytica YALI0D07282g
YALI0D06754g
A. nidulans AN5397
AN6830
AN9170
AN0901
AN0878
AN6635
AN8581
AN7389
N. crassa NCU02201
NCU05604
NCU00526
S. japonicus SJAG04677
S. octosporus SOCG02962
S. pombe SPAC1F7.08 (FIO1)
YFL041W (FET5) Multicopper oxidase, integral membrane protein with similarity to Fet3p; may have a role in iron transport
YMR058W (FET3) Ferro-O2-oxidoreductase required for high-affinity iron uptake and involved in mediating resistance to copper ion toxicity, belongs to class of integral membrane multicopper oxidases
orf19.943 Putative multicopper ferro-O2-oxidoreductase; downregulated in core caspofungin response; fungal-specific (no human or murine homolog)
orf19.4211 (FET3) Multicopper oxidase; required for growth under low-iron conditions; null mutant shows decreased prostaglandin E2 production; functional homolog of S. cerevisiae Fet3p; ketoconazole, caspofungin, amphotericin B repressed
orf19.4212 (FET99) Protein of multicopper oxidase family; similar to S. cerevisiae Fet3p; does not functionally complement S. cerevisiae fet3 mutant growth under low-iron conditions; iron-repressed transcription; regulated by Tup1p, Rim101p
orf19.4215 (FET34) Protein similar to multicopper ferroxidase; expression greater in low iron and reduced in a fluconazole-resistant isolate; downregulated by Sfu1p, Hog1p; alkaline upregulated by Rim101p; ciclopirox olamine induced
SPAC1F7.08 (FIO1) iron transport multicopper oxidase Fio1

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