Gene: Human HLA-C (3107)
major histocompatibility complex, class I, C
- Source:
- NCBI, updated 2019-10-01
- Taxon:
- Homo sapiens (human)
- Chromosome:
- 6
- Wildtype Transcripts:
- NM_001243042.1, NM_002117.6
shRNA constructs with 100% match to this gene
Matching is performed using the Specificity-Defining Region (SDR)[?]The SDR or "Specificity-Defining Region" encompasses the 19 bases within the shRNA stem region that are retained during siRNA processing/production. These are thus the bases that define the target specificity of the shRNA. Note that, while our shRNA designs nearly always extend the stem by two additional bases matching the intended target transcript (reported in the "Target Seq" column), these additional bases are not relevant to target specificity. of the shRNAs. This list includes matches to any current transcript from gene 3107 (HLA-C), regardless of what transcript the shRNAs were originally designed to target. For example, some shRNAs in this list may have been originally designed to target: (i) a transcript of an orthologous gene (in this collection, generally human-to-mouse or mouse-to-human), or (ii) a transcript of a different gene from the same or different taxon.
shRNA constructs with at least a near match to this gene
This list includes shRNAs that have a >84% (16 of 19 bases) SDR[?]The SDR or "Specificity-Defining Region" encompasses the 19 bases within the shRNA stem region that are retained during siRNA processing/production. These are thus the bases that define the target specificity of the shRNA. Note that, while our shRNA designs nearly always extend the stem by two additional bases matching the intended target transcript (reported in the "Target Seq" column), these additional bases are not relevant to target specificity.match to transcripts from gene 3107 (HLA-C), regardless of what transcript they were originally designed to target. For example, this list can include shRNAs that were originally designed to target: (i) a transcript of an orthologous gene (in this collection, generally human-to-mouse or mouse-to-human), or (ii) a transcript of a different gene from the same or different taxon.