Construct: sgRNA BRDN0001144895
Construct Description:
- Construct Type:
- sgRNA
- Other Identifiers:
- n/a
- DNA Barcode:
- TATGGGAGACCTACCAGAGT
Original Target:
- Taxon:
-
Homo sapiens (human)
- Gene:
- CAMK1D (57118)
- Gene Description:
- n/a
- CRISPR Mechanism
- CRISPRko
Vector Information:
- Vector Backbone:
- pXPR_003
- Pol II Cassette 1:
- EF1A-PuroR
- Pol II Cassette 2:
- n/a
- Selection Marker:
- PuroR
- Visible Reporter:
- n/a
- Epitope Tag:
- n/a
Additional Information:
- Addgene ID:
- 77443
Gene matches for this target sequence (CRISPRko, PAM=NGG, human):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000010.11 |
10 |
12814305 |
- |
CAMK1D |
NNNGGGAGACCTACCAGAGT |
NGG |
0 |
1.0 |
Tier I |
2 |
NC_000015.10 |
15 |
48760215 |
- |
CEP152 |
NNNGGGAGAACTACCAGAGC |
NGG |
2 |
0.0788 |
Tier I |
3 |
NC_000001.11 |
1 |
15651791 |
+ |
DDI2 |
NNNGGGAGAGCTACCAGAGT |
NTG |
2 |
0.0152 |
Tier I |
4 |
NC_000012.12 |
12 |
53224592 |
- |
RARG |
NNNGGGAAACCTTCCAGAGT |
NGG |
2 |
0.3 |
Tier II |
5 |
NC_000022.11 |
22 |
31633968 |
- |
PISD |
NNNGGGAGTCCTAACAGAGT |
NGG |
2 |
0.21 |
Tier II |
6 |
NC_000019.10 |
19 |
4901858 |
- |
ARRDC5 |
NNNGGGAGACCTTCCAGAGA |
NGG |
2 |
0.1687 |
Tier II |
7 |
NC_000012.12 |
12 |
100504955 |
+ |
NR1H4 |
NNNGGCAGACCTCCCAGAGT |
NGG |
2 |
0.1435 |
Tier II |
8 |
NC_000012.12 |
12 |
3532961 |
+ |
PRMT8 |
NNNGGGAGGCCTCCCAGAGT |
NGG |
2 |
0.1404 |
Tier II |
9 |
NC_000015.10 |
15 |
33744615 |
+ |
RYR3 |
NNNGGGACACCTCCCAGAGT |
NGG |
2 |
0.1296 |
Tier II |
10 |
NC_000009.12 |
9 |
5114432 |
+ |
JAK2 |
NNNGGGAGACCTACCAGTGC |
NGG |
2 |
0.0455 |
Tier II |
11 |
NC_000009.12 |
9 |
5114432 |
+ |
INSL6 |
NNNGGGAGACCTACCAGTGC |
NGG |
2 |
0.0455 |
Tier II |
12 |
NC_000002.12 |
2 |
73269893 |
+ |
FBXO41 |
NNNGGGAGACCTCCCAGAGG |
NGG |
2 |
0.0372 |
Tier II |
13 |
NC_000003.12 |
3 |
89150504 |
+ |
EPHA3 |
NNNGGGAGACCTTCTAGAGT |
NGG |
2 |
0.02 |
Tier II |
14 |
NC_000017.11 |
17 |
18388458 |
+ |
EVPLL |
NNNGGGAGACCCAGCAGAGT |
NGG |
2 |
0.0 |
Tier II |
15 |
NC_000012.12 |
12 |
53341174 |
- |
SP7 |
NNNGGGAGACCTAGCAGAGA |
NGG |
2 |
0.0 |
Tier II |
16 |
NC_000002.12 |
2 |
217536778 |
+ |
DIRC3 |
NNNGGCAGCCCTACCAGAGT |
NGG |
2 |
0.3896 |
Tier III |
17 |
NC_000007.14 |
7 |
26617783 |
- |
LOC101928077 |
NNNGGGAGACCTCCCAGTGT |
NGG |
2 |
0.1053 |
Tier III |
18 |
NC_000022.11 |
22 |
34107779 |
- |
LINC01643 |
NNNGGGAGACCCACCAGAGC |
NGG |
2 |
0.0861 |
Tier III |
19 |
NC_000009.12 |
9 |
5114432 |
+ |
IGHEP2 |
NNNGGGAGACCTACCAGTGC |
NGG |
2 |
0.0455 |
Tier III |
20 |
NC_000014.9 |
14 |
105600542 |
- |
IGH |
NNNGGGAGACCTACCAGTGC |
NGG |
2 |
0.0455 |
Tier III |
21 |
NC_000014.9 |
14 |
105600542 |
- |
IGHE |
NNNGGGAGACCTACCAGTGC |
NGG |
2 |
0.0455 |
Tier III |
22 |
NC_000014.9 |
14 |
105722270 |
- |
IGH |
NNNGGGAGACCTACCAGTGC |
NGG |
2 |
0.0455 |
Tier III |
23 |
NC_000014.9 |
14 |
105722270 |
- |
IGHEP1 |
NNNGGGAGACCTACCAGTGC |
NGG |
2 |
0.0455 |
Tier III |
24 |
NC_000001.11 |
1 |
193520477 |
- |
LOC124904475 |
NNNGGGAGACCTACCAGTGT |
NGT |
2 |
0.0081 |
Tier III |
Gene matches for this target sequence (CRISPRko, PAM=NGG, mouse):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000067.6 |
1 |
74375819 |
+ |
Slc11a1 |
NNNGGGAGACCTACCTGAGT |
NAG |
2 |
0.0 |
Tier I |
2 |
NC_000086.7 |
X |
36851672 |
+ |
C330007P06Rik |
NNNAGGAGACCAACCAGAGT |
NGG |
2 |
0.72 |
Tier II |
3 |
NC_000078.6 |
12 |
73743252 |
- |
Prkch |
NNNGGGAGACCAATCAGAGT |
NGG |
2 |
0.5867 |
Tier II |
4 |
NC_000073.6 |
7 |
73941870 |
+ |
St8sia2 |
NNNGGGAGGCCTAACAGAGT |
NGG |
2 |
0.2333 |
Tier II |
5 |
NC_000080.6 |
14 |
12171815 |
+ |
Ptprg |
NNNTGGAGACCTACCAGGGT |
NGG |
2 |
0.1455 |
Tier II |
6 |
NC_000072.6 |
6 |
125051375 |
+ |
Acrbp |
NNNGTGAGACCTCCCAGAGT |
NGG |
2 |
0.0632 |
Tier II |
7 |
NC_000073.6 |
7 |
122392464 |
- |
Prkcb |
NNNGGCAGACCTACCAGAGT |
NTG |
2 |
0.0266 |
Tier II |
8 |
NC_000074.6 |
8 |
54892145 |
- |
Gpm6a |
NNNGGGAGACCTAGCAGAGT |
NGG |
1 |
0.0 |
Tier II |
9 |
NC_000078.6 |
12 |
53716562 |
+ |
Npas3 |
NNNGGGAGACCTAGCATAGT |
NGG |
2 |
0.0 |
Tier II |
10 |
NC_000081.6 |
15 |
52744512 |
+ |
Gm41323 |
NNNGGGAGACCCAGCAGAGT |
NGG |
2 |
0.0 |
Tier III |
Other clones with same target sequence:
(none)