Construct: sgRNA BRDN0001145029
Construct Description:
- Construct Type:
- sgRNA
- Other Identifiers:
- n/a
- DNA Barcode:
- ACGGCATATGAACTGCTGAG
Original Target:
- Taxon:
-
Homo sapiens (human)
- Gene:
- STK32A (202374)
- Gene Description:
- n/a
- CRISPR Mechanism
- CRISPRko
Vector Information:
- Vector Backbone:
- pXPR_003
- Pol II Cassette 1:
- EF1A-PuroR
- Pol II Cassette 2:
- n/a
- Selection Marker:
- PuroR
- Visible Reporter:
- n/a
- Epitope Tag:
- n/a
Additional Information:
- Addgene ID:
- 76474
Gene matches for this target sequence (CRISPRko, PAM=NGG, human):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000005.10 |
5 |
147361605 |
+ |
STK32A |
NNNGCATATGAACTGCTGAG |
NGG |
0 |
1.0 |
Tier I |
2 |
NC_000009.12 |
9 |
69447927 |
- |
APBA1 |
NNNGCATGAGAACTGCTGAG |
NGG |
2 |
0.681 |
Tier II |
3 |
NC_000012.12 |
12 |
11789405 |
- |
ETV6 |
NNNGCATCTGAACTACTGAG |
NGG |
2 |
0.4034 |
Tier II |
4 |
NC_000017.11 |
17 |
81551326 |
- |
FAAP100 |
NNNGCAGATGGACTGCTGAG |
NGG |
2 |
0.3824 |
Tier II |
5 |
NC_000020.11 |
20 |
20177797 |
+ |
CFAP61 |
NNNGGATAGGAACTGCTGAG |
NGG |
2 |
0.3714 |
Tier II |
6 |
NC_000010.11 |
10 |
131215367 |
+ |
TCERG1L |
NNNACATATCAACTGCTGAG |
NGG |
2 |
0.36 |
Tier II |
7 |
NC_000003.12 |
3 |
52922870 |
+ |
SFMBT1 |
NNNGCCTATGGACTGCTGAG |
NGG |
2 |
0.2955 |
Tier II |
8 |
NC_000006.12 |
6 |
70828541 |
- |
SMAP1 |
NNNGCATATGAACTGCAGTG |
NGG |
2 |
0.2872 |
Tier II |
9 |
NC_000006.12 |
6 |
72064451 |
+ |
RIMS1 |
NNNGCATATGAATTGTTGAG |
NGG |
2 |
0.2154 |
Tier II |
10 |
NC_000004.12 |
4 |
152519962 |
+ |
FBXW7 |
NNNTCATATGAACTGCTGTG |
NGG |
2 |
0.1958 |
Tier II |
11 |
NC_000006.12 |
6 |
157184095 |
+ |
ARID1B |
NNNGCCTATGCACTGCTGAG |
NGG |
2 |
0.1818 |
Tier II |
12 |
NC_000005.10 |
5 |
116091706 |
- |
COMMD10 |
NNNGCATATGAACTGCTGAA |
NGA |
2 |
0.0651 |
Tier II |
13 |
NC_000014.9 |
14 |
68505911 |
+ |
RAD51B |
NNNGCATATGTACTGCTGAG |
NGA |
2 |
0.0214 |
Tier II |
14 |
NC_000013.11 |
13 |
91492637 |
- |
GPC5 |
NNNGCATATGAACTGGTGAG |
NTG |
2 |
0.006 |
Tier II |
15 |
NC_000010.11 |
10 |
95169213 |
- |
LOC107984257 |
NNNGTATATGAATTGCTGAG |
NGG |
2 |
0.4455 |
Tier III |
16 |
NC_000003.12 |
3 |
129321540 |
- |
H1-10-AS1 |
NNNGCATGTGAACTGGTGAG |
NGG |
2 |
0.1128 |
Tier III |
Gene matches for this target sequence (CRISPRko, PAM=NGG, mouse):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000084.6 |
18 |
43305088 |
+ |
Stk32a |
NNNGCTTACGAACTGCTGAG |
NGG |
2 |
0.6593 |
Tier I |
2 |
NC_000079.6 |
13 |
57744394 |
- |
Spock1 |
NNNACATGTGAACTGCTGAG |
NGG |
2 |
0.66 |
Tier II |
3 |
NC_000072.6 |
6 |
72672827 |
- |
Tcf7l1 |
NNNGCATAGGAACTGCTGAG |
NGG |
1 |
0.619 |
Tier II |
4 |
NC_000071.6 |
5 |
38281214 |
+ |
Otop1 |
NNNGCATATTAACTGCTTAG |
NGG |
2 |
0.5417 |
Tier II |
5 |
NC_000078.6 |
12 |
110637949 |
+ |
Dync1h1 |
NNNGCAGATGAGCTGCTGAG |
NGG |
2 |
0.4248 |
Tier II |
6 |
NC_000076.6 |
10 |
73463084 |
- |
Pcdh15 |
NNNGGACATGAACTGCTGAG |
NGG |
2 |
0.4125 |
Tier II |
7 |
NC_000069.6 |
3 |
82114922 |
- |
Gucy1a1 |
NNNGCAGAGGAACTGCTGAG |
NGG |
2 |
0.3641 |
Tier II |
8 |
NC_000079.6 |
13 |
33006760 |
+ |
Serpinb9 |
NNNGCATAAGAACTGCTGAG |
NAG |
2 |
0.2407 |
Tier II |
9 |
NC_000069.6 |
3 |
36643265 |
+ |
Trpc3 |
NNNTCATATGAACTGCTGTG |
NGG |
2 |
0.1958 |
Tier II |
10 |
NC_000068.7 |
2 |
101575794 |
- |
Iftap |
NNNGCATATGAACTGCTCAG |
NAG |
2 |
0.1235 |
Tier II |
11 |
NC_000072.6 |
6 |
89673479 |
+ |
Txnrd3 |
NNNGCATATGGAGTGCTGAG |
NGG |
2 |
0.0886 |
Tier II |
12 |
NC_000079.6 |
13 |
43083190 |
- |
Phactr1 |
NNNGCATATGAACTACTGAG |
NGA |
2 |
0.0654 |
Tier II |
13 |
NC_000080.6 |
14 |
14983058 |
- |
Nek10 |
NNNGCATAAGAACTGCTGAG |
NGA |
2 |
0.0645 |
Tier II |
14 |
NC_000073.6 |
7 |
19880555 |
+ |
Ceacam19 |
NNNGCATAAGAACTGCTGAG |
NTG |
2 |
0.0362 |
Tier II |
15 |
NC_000081.6 |
15 |
81954885 |
+ |
Pmm1 |
NNNGCATTTGAACTGCTGAG |
NGA |
2 |
0.0298 |
Tier II |
16 |
NC_000070.6 |
4 |
18878938 |
- |
Cnbd1 |
NNNGCATATGAACTGTTGAG |
NGA |
2 |
0.0214 |
Tier II |
17 |
NC_000072.6 |
6 |
72672827 |
- |
Gm31391 |
NNNGCATAGGAACTGCTGAG |
NGG |
1 |
0.619 |
Tier III |
18 |
NC_000079.6 |
13 |
16164018 |
+ |
Gm31711 |
NNNGCATATGAACTGGTCAG |
NGG |
2 |
0.0733 |
Tier III |
19 |
NC_000077.6 |
11 |
75268740 |
- |
Gm35117 |
NNNGCATATGAGCTGCTGAG |
NGA |
2 |
0.0502 |
Tier III |
20 |
NC_000083.6 |
17 |
19840162 |
- |
Vmn2r-ps123 |
NNNGCACATGAACTGCTGAG |
NGT |
2 |
0.0111 |
Tier III |
Other clones with same target sequence:
(none)