Construct: sgRNA BRDN0001145146
Construct Description:
- Construct Type:
- sgRNA
- Other Identifiers:
- n/a
- DNA Barcode:
- TGACATGACCAGCAATAAAG
Original Target:
- Taxon:
-
Homo sapiens (human)
- Gene:
- STK36 (27148)
- Gene Description:
- n/a
- CRISPR Mechanism
- CRISPRko
Vector Information:
- Vector Backbone:
- pXPR_003
- Pol II Cassette 1:
- EF1A-PuroR
- Pol II Cassette 2:
- n/a
- Selection Marker:
- PuroR
- Visible Reporter:
- n/a
- Epitope Tag:
- n/a
Additional Information:
- Addgene ID:
- 77276
Gene matches for this target sequence (CRISPRko, PAM=NGG, human):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000002.12 |
2 |
218679242 |
- |
STK36 |
NNNCATGACCAGCAATAAAG |
NGG |
0 |
1.0 |
Tier I |
2 |
NC_000023.11 |
X |
31729661 |
- |
DMD |
NNNCAAGACCAGCAATCAAG |
NGG |
2 |
0.1529 |
Tier I |
3 |
NC_000017.11 |
17 |
29896637 |
- |
SSH2 |
NNNAAAGACCAGCAATAAAG |
NGG |
2 |
0.7298 |
Tier II |
4 |
NC_000023.11 |
X |
47878655 |
+ |
ZNF81 |
NNNAATGACAAGCAATAAAG |
NGG |
2 |
0.7298 |
Tier II |
5 |
NC_000001.11 |
1 |
183945267 |
- |
COLGALT2 |
NNNCAAGACCAGCAACAAAG |
NGG |
2 |
0.5778 |
Tier II |
6 |
NC_000019.10 |
19 |
57220172 |
- |
ZNF264 |
NNNCATGAGAAGCAATAAAG |
NGG |
2 |
0.5365 |
Tier II |
7 |
NC_000008.11 |
8 |
112900851 |
- |
CSMD3 |
NNNCATTAACAGCAATAAAG |
NGG |
2 |
0.4898 |
Tier II |
8 |
NC_000002.12 |
2 |
55528267 |
- |
CFAP36 |
NNNGATGATCAGCAATAAAG |
NGG |
2 |
0.4375 |
Tier II |
9 |
NC_000002.12 |
2 |
2105493 |
- |
MYT1L |
NNNCATGAGCAGAAATAAAG |
NGG |
2 |
0.2381 |
Tier II |
10 |
NC_000011.10 |
11 |
24618078 |
- |
LUZP2 |
NNNCATGCCCAGCAATAATG |
NGG |
2 |
0.2308 |
Tier II |
11 |
NC_000011.10 |
11 |
103215096 |
+ |
DYNC2H1 |
NNNCATGCCCAGCTATAAAG |
NGG |
2 |
0.2286 |
Tier II |
12 |
NC_000002.12 |
2 |
80498252 |
- |
CTNNA2 |
NNNCATGTCCAGCTATAAAG |
NGG |
2 |
0.2286 |
Tier II |
13 |
NC_000003.12 |
3 |
189880674 |
- |
TP63 |
NNNCATGACCAGCATTAAAA |
NGG |
2 |
0.1875 |
Tier II |
14 |
NC_000001.11 |
1 |
36970731 |
- |
GRIK3 |
NNNCATGACCAGCAATGAAG |
NGG |
1 |
0.1765 |
Tier II |
15 |
NC_000003.12 |
3 |
9247810 |
+ |
SRGAP3 |
NNNCATGACCAGAAAGAAAG |
NGG |
2 |
0.1331 |
Tier II |
16 |
NC_000008.11 |
8 |
78559315 |
+ |
PKIA |
NNNCATGATCAGCAATTAAG |
NGG |
2 |
0.1167 |
Tier II |
17 |
NC_000007.14 |
7 |
147935698 |
- |
CNTNAP2 |
NNNCATGACCAGAATTAAAG |
NGG |
2 |
0.0769 |
Tier II |
18 |
NC_000010.11 |
10 |
22941902 |
- |
ARMC3 |
NNNCATGACCAGCAATTGAG |
NGG |
2 |
0.0533 |
Tier II |
19 |
NC_000003.12 |
3 |
107320895 |
+ |
DUBR |
NNNTATGACCAACAATAAAG |
NGG |
2 |
0.7467 |
Tier III |
20 |
NC_000003.12 |
3 |
28018475 |
+ |
LINC01967 |
NNNCATGTCCAGCAATAAAA |
NGG |
2 |
0.4018 |
Tier III |
21 |
NC_000017.11 |
17 |
32428675 |
- |
NUDT15P2 |
NNNCATGACCAGCAACAGAG |
NGG |
2 |
0.2667 |
Tier III |
22 |
NC_000001.11 |
1 |
209373538 |
+ |
LINC01698 |
NNNCATGACCAGCAAGAGAG |
NGG |
2 |
0.1385 |
Tier III |
23 |
NC_000008.11 |
8 |
78559315 |
+ |
LOC105375911 |
NNNCATGATCAGCAATTAAG |
NGG |
2 |
0.1167 |
Tier III |
Gene matches for this target sequence (CRISPRko, PAM=NGG, mouse):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000076.6 |
10 |
33780361 |
- |
Sult3a2 |
NNNCATGAACAACAATAAAG |
NGG |
2 |
0.8 |
Tier II |
2 |
NC_000070.6 |
4 |
43659634 |
- |
Fam221b |
NNNCAAGATCAGCAATAAAG |
NGG |
2 |
0.7583 |
Tier II |
3 |
NC_000070.6 |
4 |
145140307 |
+ |
Vps13d |
NNNTATGACCAGCAACAAAG |
NGG |
2 |
0.5333 |
Tier II |
4 |
NC_000084.6 |
18 |
7411887 |
- |
Mpp7 |
NNNCATGACCAGAAATAAAG |
NGG |
1 |
0.3846 |
Tier II |
5 |
NC_000074.6 |
8 |
88574678 |
+ |
Nkd1 |
NNNTATGACCAGCAATAGAG |
NGG |
2 |
0.32 |
Tier II |
6 |
NC_000068.7 |
2 |
70288835 |
- |
Myo3b |
NNNCATGAACAGCAAGAAAG |
NGG |
2 |
0.2967 |
Tier II |
7 |
NC_000074.6 |
8 |
45313378 |
+ |
Cyp4v3 |
NNNCATGACCATCTATAAAG |
NGG |
2 |
0.2051 |
Tier II |
8 |
NC_000086.7 |
X |
137927358 |
- |
Il1rapl2 |
NNNCATGACAAGGAATAAAG |
NGG |
2 |
0.1182 |
Tier II |
9 |
NC_000071.6 |
5 |
107345971 |
- |
Brdt |
NNNCATGACCAGCGATAAAG |
NGT |
2 |
0.0075 |
Tier II |
10 |
NC_000086.7 |
X |
7295530 |
+ |
Clcn5 |
NNNCATGCCCAGCAATAAAG |
NGT |
2 |
0.0069 |
Tier II |
11 |
NC_000082.6 |
16 |
6157405 |
- |
Rbfox1 |
NNNCATGACCAGCAATAAAG |
NAC |
2 |
0.0 |
Tier II |
12 |
NC_000070.6 |
4 |
43659634 |
- |
Gm4748 |
NNNCAAGATCAGCAATAAAG |
NGG |
2 |
0.7583 |
Tier III |
13 |
NC_000074.6 |
8 |
45313378 |
+ |
Gm30504 |
NNNCATGACCATCTATAAAG |
NGG |
2 |
0.2051 |
Tier III |
14 |
NC_000071.6 |
5 |
43180325 |
+ |
Gm7854 |
NNNCATGACCAGCAAAACAG |
NGG |
2 |
0.1732 |
Tier III |
15 |
NC_000078.6 |
12 |
32932619 |
+ |
4933406C10Rik |
NNNCCTGACCAGCAAGAAAG |
NGG |
2 |
0.1731 |
Tier III |
16 |
NC_000074.6 |
8 |
103297624 |
+ |
Gm39234 |
NNNCATGAGCAGCCATAAAG |
NGG |
2 |
0.1327 |
Tier III |
17 |
NC_000068.7 |
2 |
132642874 |
- |
AU019990 |
NNNCATGACCACCAATGAAG |
NGG |
2 |
0.0934 |
Tier III |
Other clones with same target sequence:
(none)