Construct: sgRNA BRDN0001145169
Construct Description:
- Construct Type:
- sgRNA
- Other Identifiers:
- n/a
- DNA Barcode:
- CTCGGACCACATATTCAGGA
Original Target:
- Taxon:
-
Homo sapiens (human)
- Gene:
- MST1R (4486)
- Gene Description:
- n/a
- CRISPR Mechanism
- CRISPRko
Vector Information:
- Vector Backbone:
- pXPR_003
- Pol II Cassette 1:
- EF1A-PuroR
- Pol II Cassette 2:
- n/a
- Selection Marker:
- PuroR
- Visible Reporter:
- n/a
- Epitope Tag:
- n/a
Additional Information:
- Addgene ID:
- 78052
Gene matches for this target sequence (CRISPRko, PAM=NGG, human):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000003.12 |
3 |
49896364 |
+ |
MST1R |
NNNGGACCACATATTCAGGA |
NGG |
0 |
1.0 |
Tier I |
2 |
NC_000010.11 |
10 |
35148732 |
- |
CREM |
NNNGGATTACATATTCAGGA |
NGG |
2 |
0.7109 |
Tier II |
3 |
NC_000006.12 |
6 |
12081076 |
- |
HIVEP1 |
NNNGGACCAAATATACAGGA |
NGG |
2 |
0.5018 |
Tier II |
4 |
NC_000017.11 |
17 |
36493675 |
+ |
ZNHIT3 |
NNNGGACCACATATACAGTA |
NGG |
2 |
0.386 |
Tier II |
5 |
NC_000004.12 |
4 |
7253328 |
- |
SORCS2 |
NNNGGGCCACAGATTCAGGA |
NGG |
2 |
0.3571 |
Tier II |
6 |
NC_000007.14 |
7 |
129871034 |
- |
UBE2H |
NNNGGATCAGATATTCAGGA |
NGG |
2 |
0.316 |
Tier II |
7 |
NC_000020.11 |
20 |
49454557 |
+ |
KCNB1 |
NNNGGAGCACATATTCAGGT |
NGG |
2 |
0.2824 |
Tier II |
8 |
NC_000017.11 |
17 |
32670942 |
+ |
MYO1D |
NNNGGACCAGATATTCAGAA |
NGG |
2 |
0.2778 |
Tier II |
9 |
NC_000019.10 |
19 |
9533686 |
+ |
ZNF426 |
NNNGGACCACATTTTCAGAA |
NGG |
2 |
0.2143 |
Tier II |
10 |
NC_000017.11 |
17 |
2075304 |
+ |
SMG6 |
NNNGGACTACATCTTCAGGA |
NGG |
2 |
0.1842 |
Tier II |
11 |
NC_000007.14 |
7 |
158213292 |
+ |
PTPRN2 |
NNNGAACCACATATTCTGGA |
NGG |
2 |
0.1156 |
Tier II |
12 |
NC_000017.11 |
17 |
57427562 |
- |
MSI2 |
NNNGGACCACATAATGAGGA |
NGG |
2 |
0.0952 |
Tier II |
13 |
NC_000015.10 |
15 |
85047764 |
+ |
PDE8A |
NNNAGACCACATATTCAGGA |
NTG |
2 |
0.0351 |
Tier II |
14 |
NC_000011.10 |
11 |
89787257 |
+ |
TRIM49 |
NNNGGACCACATAGTCAGGA |
NGA |
2 |
0.0 |
Tier II |
15 |
NC_000011.10 |
11 |
90052421 |
- |
TRIM49C |
NNNGGACCACATAGTCAGGA |
NGA |
2 |
0.0 |
Tier II |
16 |
NC_000011.10 |
11 |
49048852 |
- |
ANKRD33BP3 |
NNNGGACCACATAGTCAGGA |
NGA |
2 |
0.0 |
Tier III |
17 |
NC_000011.10 |
11 |
89787257 |
+ |
ANKRD33BP7 |
NNNGGACCACATAGTCAGGA |
NGA |
2 |
0.0 |
Tier III |
18 |
NC_000011.10 |
11 |
90052421 |
- |
ANKRD33BP10 |
NNNGGACCACATAGTCAGGA |
NGA |
2 |
0.0 |
Tier III |
Gene matches for this target sequence (CRISPRko, PAM=NGG, mouse):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000077.6 |
11 |
80374122 |
+ |
5730455P16Rik |
NNNAGACCACATATTCAGAA |
NGG |
2 |
0.6429 |
Tier I |
2 |
NC_000073.6 |
7 |
107934198 |
- |
Olfr473 |
NNNGGAGCGCATATTCAGGA |
NGG |
2 |
0.3137 |
Tier I |
3 |
NC_000073.6 |
7 |
107991043 |
- |
Olfr477 |
NNNGGAGCGCATATTCAGGA |
NGG |
2 |
0.3137 |
Tier I |
4 |
NC_000079.6 |
13 |
73511326 |
- |
Lpcat1 |
NNNCGACCACATATTCACGA |
NGG |
2 |
0.2521 |
Tier I |
5 |
NC_000075.6 |
9 |
107914759 |
- |
Mst1r |
NNNGGACCACATATTCAGGC |
NGG |
1 |
0.2273 |
Tier I |
6 |
NC_000069.6 |
3 |
103836156 |
- |
Bcl2l15 |
NNNGGACCACATATTCAAGA |
NGT |
2 |
0.0112 |
Tier I |
7 |
NC_000067.6 |
1 |
158290496 |
+ |
Brinp2 |
NNNGAACCACACATTCAGGA |
NGG |
2 |
0.8211 |
Tier II |
8 |
NC_000082.6 |
16 |
6004188 |
+ |
Rbfox1 |
NNNGGATCACAAATTCAGGA |
NGG |
2 |
0.65 |
Tier II |
9 |
NC_000069.6 |
3 |
35974345 |
+ |
Mccc1 |
NNNGGACAACACATTCAGGA |
NGG |
2 |
0.6158 |
Tier II |
10 |
NC_000083.6 |
17 |
52745671 |
+ |
Kcnh8 |
NNNGGAACACATATTCAGTA |
NGG |
2 |
0.5 |
Tier II |
11 |
NC_000081.6 |
15 |
91534211 |
+ |
Slc2a13 |
NNNGGACAACATAATCAGGA |
NGG |
2 |
0.4024 |
Tier II |
12 |
NC_000071.6 |
5 |
62812316 |
+ |
Dthd1 |
NNNGGACCACATTTTAAGGA |
NGG |
2 |
0.3 |
Tier II |
13 |
NC_000074.6 |
8 |
78584564 |
+ |
Slc10a7 |
NNNGGACCACAGATACAGGA |
NGG |
2 |
0.2895 |
Tier II |
14 |
NC_000067.6 |
1 |
37400976 |
+ |
Inpp4a |
NNNGGGCCACATATTTAGGA |
NGG |
2 |
0.2198 |
Tier II |
15 |
NC_000073.6 |
7 |
96384840 |
+ |
Tenm4 |
NNNGGACCACATATTCATGC |
NGG |
2 |
0.1515 |
Tier II |
16 |
NC_000067.6 |
1 |
193235910 |
+ |
Hsd11b1 |
NNNGGACCACACATTGAGGA |
NGG |
2 |
0.1457 |
Tier II |
17 |
NC_000068.7 |
2 |
119542134 |
+ |
Exd1 |
NNNGGACCACAGCTTCAGGA |
NGG |
2 |
0.1053 |
Tier II |
18 |
NC_000082.6 |
16 |
96317095 |
- |
B3galt5 |
NNNGGACCACAGATTCAGGA |
NGA |
2 |
0.0347 |
Tier II |
19 |
NC_000067.6 |
1 |
9191805 |
- |
Sntg1 |
NNNGGACCACATATCCAGGA |
NTG |
2 |
0.0106 |
Tier II |
20 |
NC_000071.6 |
5 |
50155419 |
- |
4930448I18Rik |
NNNGGGCCACATATGCAGGA |
NGG |
2 |
0.0357 |
Tier III |
Other clones with same target sequence:
(none)